Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 5, 2014, Pages

  Varma, Saaket ^a   Mahavadi, Poornima ^b   Sasikumar, Satish ^a   Cushing, Leah ^c   Hyland, Tessa ^a   Rosser, Ann E ^d   Riccardi, Daniela ^e   Lu, Jining ^c   Kalin, Tanya V ^f   Kalinichenko, Vladimir V ^f   Guenther, Andreas ^b,g   Ramirez, Maria I ^c   Pardo, Annie ^h   Selman, Moisés ⁱ   Warburton, David ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d LLANDOUGH HOSPITAL   (United Kingdom)

^e CARDIFF UNIVERSITY   (United Kingdom)

^f CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^g Agaplesion Lung Clinic Waldhof Elgerhausen   (Germany)

^h UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

ⁱ INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

Author keywords

Cell flattening; Epithelial integrity; Epithelial plasticity; GRHL2; Idiopathic pulmonary fibrosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GRAINYHEAD LIKE 2 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VIMENTIN; DNA BINDING PROTEIN; GRAINY HEAD LIKE 2 PROTEIN, MOUSE; GRAINY HEAD-LIKE 2 PROTEIN, MOUSE; GRHL2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FIBROSING ALVEOLITIS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IN VITRO STUDY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; MALE; MOUSE; NONHUMAN; OPEN LUNG BIOPSY; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PURIFICATION; TIGHT JUNCTION; ANIMAL; CELL FLATTENING; COMPARATIVE STUDY; CYTOLOGY; DISEASE MODEL; EPITHELIAL INTEGRITY; EPITHELIAL PLASTICITY; FEMALE; FETUS; GENE EXPRESSION REGULATION; GENETICS; GRHL2; LUNG ALVEOLUS; MESODERM; METABOLISM; MIDDLE AGED; MUTANT MOUSE STRAIN; PHYSIOLOGY; PREGNANCY; RESPIRATORY TRACT MUCOSA; SPECIES DIFFERENCE;

CELL FLATTENING; EPITHELIAL INTEGRITY; EPITHELIAL PLASTICITY; GRHL2; IDIOPATHIC PULMONARY FIBROSIS;

ANIMALS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; MESODERM; MICE; MICE, MUTANT STRAINS; MIDDLE AGED; PREGNANCY; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 84900562074     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00143.2013     Document Type: Article

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