Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia

American Journal of Respiratory and Critical Care Medicine

Volumn 182, Issue 2, 2010, Pages 207-219

  Mahavadi, Poornima ^a   Korfei, Martina ^a   Henneke, Ingrid ^a   Liebisch, Gerhard ^b   Schmitz, Gerd ^b   Gochuico, Bernadette R ^c   Markart, Philipp ^a   Bellusci, Saverio ^a   Seeger, Werner ^a   Ruppert, Clemens ^a   Guenther, Andreas ^a,d  

^a JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d Lung Clinic Waldhof Elgershausen   (Germany)

Author keywords

Adaptor protein 3; Apoptosis; Biogenesis of lysosome related organelle complex; Cathepsin D; Pulmonary surfactant

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 3; CATHEPSIN D; PHOSPHOLIPID; SURFACTANT PHOSPHOLIPID; SURFACTANT PROTEIN B; SURFACTANT PROTEIN C; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CTSD PROTEIN, MOUSE; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PEPTIDE; SFTPC PROTEIN, MOUSE; TCF4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL INFILTRATION; CELL PROLIFERATION; CELL STRESS; DISEASE ASSOCIATION; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERSTITIAL PNEUMONIA; LIPIDOMICS; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LYSOSOME; MORPHOMETRICS; MOUSE; NONHUMAN; OCULAR ALBINISM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DISEASE MODEL; ENDOPLASMIC RETICULUM; EPITHELIUM CELL; FIBROSIS; INTERSTITIAL LUNG DISEASE; LUNG; LUNG ALVEOLUS; LUNG LAVAGE; MACROPHAGE; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BRONCHOALVEOLAR LAVAGE FLUID; CATHEPSIN D; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; FIBROSIS; HERMANSKI-PUDLAK SYNDROME; LUNG; LUNG DISEASES, INTERSTITIAL; LYSOSOMES; MACROPHAGES; MICE; PEPTIDES; PHOSPHOLIPIDS; PULMONARY ALVEOLI; PULMONARY SURFACTANT-ASSOCIATED PROTEIN B; TRANSCRIPTION FACTOR CHOP; UP-REGULATION;

EID: 77956633080     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200909-1414OC     Document Type: Article

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