Expression of ABCA3 in developing lung and other tissues

Journal of Histochemistry and Cytochemistry

Volumn 55, Issue 1, 2007, Pages 71-83

  Stahlman, Mildred T ^b   Besnard, Valérie ^a   Wert, Susan E ^a   Weaver, Timothy E ^a   Dingle, Sharon ^a   Xu, Yan ^a   Von Zychlin, Kara ^a   Olson, Sandra J ^b   Whitsett, Jeffrey A ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

ABC transporters; Bronchopulmonary dysplasia; Immunohistochemistry; Lamellar body; Pulmonary surfactant; Thyroid transcription factor 1

Indexed keywords

ABC TRANSPORTER; LUNG SURFACTANT; MESSENGER RNA; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN ABCA3; RECOMBINANT PROTEIN; THYROID TRANSCRIPTION FACTOR 1; UNCLASSIFIED DRUG;

ADAPTATION; ADRENAL CORTEX; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL HYPERPLASIA; CELL ORGANELLE; CHRONIC LUNG DISEASE; CONTROLLED STUDY; FETUS LUNG; GESTATION PERIOD; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY CELL; LAMELLAR BODY; LIVER CELL; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; LUNG INJURY; MOUSE; NONHUMAN; PANCREAS; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; RESPIRATORY TRACT INFLAMMATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH; TISSUE GROWTH; TRACHEA;

ADULT; AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BRONCHOPULMONARY DYSPLASIA; CHILD; EPITHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; INFANT, NEWBORN; LUNG; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; RETROSPECTIVE STUDIES; RNA, MESSENGER;

EID: 33845931619     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.6A6962.2006     Document Type: Article

References (51)

1. Akiyama M, Sugiyama-Nakagiri Y, Sakai K, McMillan JR, Goto M, Arita K, Tsuji-Abe Y, et al. (2005) Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer. J Clin Invest 115:1777-1784
2. Allikmets R, Shroyer NF, Singh N, Seddon JM, Lewis RA, Bernstein PS, Peiffer A, et al. (1997) Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science 277:1805-1807
3. Bohinski RJ, DiLauro R, Whitsett JA (1994) Lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3 indicating common factors for organ-specific gene expression along the foregut axis. Mol Cell Biol 14:5671-5681
4. Brooks-Wilson A, Marcil M, Clee SM, Zhang LH, Roomp K, van Dam M, Yu L, et al. (1999) Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet 22:336-345
5. Bullard JE, Wert SE, Whitsett JA, Dean M, Nogee LM (2005) ABCA3 mutations associated with pediatric interstitial lung disease. Am J Respir Crit Care Med 172:1026-1031
6. Cheong N, Madesh M, Gonzales LW, Zaho M, Yu K, Ballard PL, Shuman H (2006) Functional and trafficking defects in ATP binding cassette A3 mutants associated with respiratory distress syndrome. J Biol Chem 281:9791-9800
7. Connors TD, Van Raay TJ, Petry LR, Klinger KW, Landes GM, Burn TC (1997) The cloning of a human ABC gene (ABC3) mapping to chromosome 16p13.3. Genomics 39:231-234
8. Dean M, Rzhetsky A, Allikmets R (2001) The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 11:1156-1166
9. deFelice M, Silberschmidt D, DiLauro R, Xu Y, Wert SE, Weaver TE, Bachurski CJ, et al. (2003) TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue specific gene expression. J Biol Chem 278:35574-35583
10. Edwards V, Cutz E, Viero S, Moore AM, Nogee L (2005) Ultrastructure of lamellar bodies in congenital surfactant deficiency. Ultrastruct Pathol 29:503-509
11. Elferink RO, Groen AK (2002) Genetic defects in hepatobiliary transport. Biochim Biophys Acta 1586:129-145 Review
12. Garmany TH, Moxley MA, White FV, Dean M, Hull WM, Whitsett JA, Nogee LM, et al. (2006) Surfactant composition and function in patients with ABCA3 mutations. Pediatr Res 59:801-805
13. Higgins CF (1992) ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8:67-113
14. Hilfer SR (1983) Development of terminal buds in the fetal mouse lung. Scan Electron Microsc (Pt 3):1387-1401
15. Holzinger A, Dingle S, Bejarano PA, Miller M-A, Weaver TE, DiLauro R, Whitsett JA (1996) Monoclonal antibody to thyroid transcription factor-1: production, characterization and usefulness in tumor diagnosis. Hybridoma 15:49-53
16. Jacobs H, Jobe A, Ikegami M, Jones S (1982) Surfactant phosphatidylcholine source, fluxes, and turnover times in 3-day-old, 10-day-old, and adult rabbits. J Biol Chem 257:1805-1810
17. Khoor A, Gray ME, Hull WM, Whitsett JA, Stahlman MT (1993) Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn. J Histochem Cytochem 41:1311-1319
18. Khoor A, Stahlman MT, Gray ME, Whitsett JA (1994) Temporal-spatial distribution of SP-B and SP-C proteins and mRNAs in the developing respiratory epithelium of human lung. J Histochem Cytochem 42:1187-1199
19. Klugbauer N, Hofmann F (1996) Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein. FEBS Lett 391:61-65
20. Lefevre C, Audebert S, Jobard F, Bouadjar B, Lakhdar H, Boughdene-Stambouli O, Blanchet-Bardon C, et al. (2003) Mutations in the transporter ABCA12 are associated with lamellar ichthyosis type 2. Hum Mol Genet 12:2369-2378
21. Mulugeta S, Gray JM, Notarfrancesco KL, Gonzales LW, Koval M, Feinstein SI, Ballard PL, et al. (2002) Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3. J Biol Chem 277:22147-22155
22. Nogee LM (2004a) Genetic mechanisms of surfactant deficiency. Biol Neonate 85:314-318
23. Nogee LM (2004b) Alterations in SP-B and SP-C expression in neonatal lung disease. Annu Rev Physiol 66:601-623
24. Nogee LM (2006) Genetics of pediatric interstitial lung disease. Curr Opin Pediatr 18:287-292
25. Pryhuber GS, Hull WM, Fink I, McMahan MJ, Whitsett JA (1991) Ontogeny of surfactant proteins A and B in human amniotic fluid as indices of fetal lung maturity. Pediatr Res 30:597-605
26. Rebhan M, Chalifa-Caspi V, Prilusky J, Lancet D (1997) GeneCards: integrating information about genes, proteins and diseases. Trends Genet 13:163
27. Rice WR, Conkright JJ, Na CL, Ikegami M, Shannon JM, Weaver TE (2002) Maintenance of the mouse type II cell phenotype in vitro. Am J Physiol 283:L256-264
28. Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, et al. (1989) Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245:1066-1073
29. Rugh R (1993) The Mouse. Oxford, Oxford University Press, 302
30. Shulenin S, Nogee LM, Annilo T, Wert SE, Whitsett JA, Dean M (2004) ABCA3 gene mutations in newborns with fatal surfactant deficiency. N Engl J Med 350:1296-1303
31. Stahlman MT, Gray ME, Hull WM, Whitsett JA (2002) Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues. J Histochem Cytochem 50:651-660
32. Stahlman MT, Gray ME, Whitsett JA (1992) The ontogeny and distribution of surfactant protein B in human fetuses and newborns. J Histochem Cytochem 40:1471-1480
33. Stahlman MT, Gray ME, Whitsett JA (1996) Expression of thyroid transcription factor-1 (TTF-1) in fetal and neonatal human lung. J Histochem Cytochem 44:673-678
34. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 101:6062-6067
35. Voorhout WF, Veenendaal T, Haagsman HP, Weaver TE, Whitsett JA, van Golde LM, Geuze HJ (1992) Intracellular processing of pulmonary surfactant protein B in an endosomal/lysosomal compartment. Am J Physiol 263:L479-486
36. Voorhout WF, Weaver TE, Haagsman HP, Geuze HJ, Van Golde LM (1993) Biosynthetic routing of pulmonary surfactant proteins in alveolar type II cells. Microsc Res Tech 26:366-373
37. Vorbroker DK, Profitt SA, Nogee LM, Whitsett JA (1995a) Aberrant processing of surfactant protein C (SP-C) in hereditary SP-B deficiency. Am J Physiol 268:L647-656
38. Vorbroker DK, Voorhout WF, Weaver TE, Whitsett JA (1995b) Post-translational processing of surfactant protein C in rat Type II cells. Am J Physiol 269:L727-733
39. Wan H, Xu Y, Ikegami M, Stahlman MT, Kaestner KH, Ang S-L, Whitsett JA (2004) Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci USA 101:14449-14454
40. Weaver TE (1998) Synthesis, processing and secretion of surfactant proteins B and C. Biochim Biophys Acta 1408:173-179
41. Weaver TE, Na CL, Stahlman M (2002) Biogenesis of lamellar bodies, lysosome-related organelles involved in storage and secretion of pulmonary surfactant. Semin Cell Dev Biol 13:263-270
42. Wert SE, Glasser SW, Korfhagen TR, Whitsett JA (1993) Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev Biol 156:426-443
43. Whitsett JA (2006) Genetic disorders of surfactant homeostasis. Paediatr Respir Rev 7:5240-242
44. Whitsett JA, Weaver TE (2002) Hydrophobic surfactant proteins in lung function and disease. N Engl J Med 347:2141-2148
45. Whitsett JA, Wert SE, Trapnell BC (2004) Genetic disorders influencing lung formation and function at birth. Hum Mol Genet 13:R207-215
46. Whitsett JA, Wert SE, Xu Y (2005) Genetic disorders of surfactant homeostasis. Biol Neonate 87:283-287
47. Wikenheiser KA, Vorbroker DK, Rice WR, Clark JC, Bachurski CJ, Oie HK, Whitsett JA (1993) Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice. Proc Natl Acad Sci USA 90:11029-11033
48. Yamano G, Funahashi H, Kawanami O, Zhao LX, Ban N, Uchida Y, Morohoshi T, et al. (2001) ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells. FEBS Lett 508:221-225
49. Yoshida I, Ban N, Inagaki N (2004) Expression of ABCA3, a causative gene for fatal surfactant deficiency, is up-regulated by glucocorticoids in lung alveolar type II cells. Biochem Biophys Res Commun 323:547-555
50. Zen K, Notarfrancesco K, Oorschot V, Slot JW, Fisher AB, Shuman H (1998) Generation and characterization of monoclonal antibodies to alveolar type II cell lamellar body membrane. Am J Physiol 275:L172-183
51. Zhou L, Lim L, Costa RH, Whitsett JA (1996) Thyroid transcription factor-1, hepatocyte nuclear factor-3β, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem 44:1183-1193