Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 9, 2014, Pages

  van der Velden, Jos L J ^a   Hoffman, Sidra M ^a   Alcorn, John F ^b   Tully, Jane E ^a   Chapman, David G ^a   Lahue, Karolyn G ^a   Guala, Amy S ^a   Lundblad, Lennart K A ^a   Aliyeva, Minara ^a   Daphtary, Nirav ^a   Irvin, Charles G ^a   Janssen Heininger, Yvonne M W ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

Airway; Epithelial to mesenchymal transition; Epithelium; Fibrosis; Lung

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COLLAGEN 1A1; COLLAGEN TYPE 1; HIGH MOBILITY GROUP AT HOOK 2 PROTEIN; HIGH MOBILITY GROUP PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA LET 7; MICRORNA LET 7G; MUCIN 5AC; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AIRWAY REMODELING; ALLERGIC AIRWAY INFLAMMATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERMATOPHAGOIDES; DISEASE ASSOCIATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE OVEREXPRESSION; HOUSE DUST ALLERGY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG LAVAGE; LUNG MUCUS METAPLASIA; LUNG PARENCHYMA; METAPLASIA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; RESPIRATORY TRACT MUCOSA; TISSUE LEVEL;

AIRWAY; EPITHELIAL-TO-MESENCHYMAL TRANSITION; EPITHELIUM; FIBROSIS; LUNG;

AIRWAY REMODELING; ANIMALS; BLOTTING, WESTERN; BRONCHIAL HYPERREACTIVITY; CYTOKINES; DERMATOPHAGOIDES PTERONYSSINUS; IMMUNOENZYME TECHNIQUES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PNEUMONIA; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84900535223     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00153.2013     Document Type: Article

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