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Volumn 5, Issue , 2014, Pages

Hepatocyte toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 4; TLR4 PROTEIN, MOUSE;

EID: 84900457238     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4878     Document Type: Article
Times cited : (239)

References (45)
  • 3
    • 84860441011 scopus 로고    scopus 로고
    • Inflammation and lipid signaling in the etiology of insulin resistance
    • Glass, C. K. & Olefsky, J. M. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 15, 635-645 (2012).
    • (2012) Cell Metab. , vol.15 , pp. 635-645
    • Glass, C.K.1    Olefsky, J.M.2
  • 5
    • 36249005027 scopus 로고    scopus 로고
    • A high-fat meal induces low-grade endotoxemia: Evidence of a novel mechanism of postprandial inflammation
    • Erridge, C., Attina, T., Spickett, C. M. & Webb, D. J. A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation. Am. J. Clin. Nutr. 86, 1286-1292 (2007). (Pubitemid 350126229)
    • (2007) American Journal of Clinical Nutrition , vol.86 , Issue.5 , pp. 1286-1292
    • Erridge, C.1    Attina, T.2    Spickett, C.M.3    Webb, D.J.4
  • 6
    • 84878232476 scopus 로고    scopus 로고
    • The history of toll-like receptors-redefining innate immunity
    • O'Neill, L. A., Golenbock, D. & Bowie, A. G. The history of Toll-like receptors-redefining innate immunity. Na. Rev. Immunol. 13, 453-460 (2013).
    • (2013) Na. Rev. Immunol. , vol.13 , pp. 453-460
    • O'Neill, L.A.1    Golenbock, D.2    Bowie, A.G.3
  • 10
  • 14
    • 0033779915 scopus 로고    scopus 로고
    • Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes
    • Matsumura, T., Ito, A., Takii, T., Hayashi, H. & Onozaki, K. Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes. J. Interferon Cytokine Res. 20, 915-921 (2000).
    • (2000) J. Interferon Cytokine Res. , vol.20 , pp. 915-921
    • Matsumura, T.1    Ito, A.2    Takii, T.3    Hayashi, H.4    Onozaki, K.5
  • 15
    • 60849102149 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker nanog
    • Machida, K. et al. Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog. Proc. Natl Acad. Sci. USA 106, 1548-1553 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 1548-1553
    • Machida, K.1
  • 20
    • 22444442654 scopus 로고    scopus 로고
    • Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis
    • Wang, A. P. et al. Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis. J. Autoimmun. 25, 85-91 (2005).
    • (2005) J. Autoimmun. , vol.25 , pp. 85-91
    • Wang, A.P.1
  • 21
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky, J. M. & Glass, C. K. Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 72, 219-246 (2010).
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 22
    • 70350389389 scopus 로고    scopus 로고
    • Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice
    • Saberi, M. et al. Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metabol. 10, 419-429 (2009).
    • (2009) Cell Metabol. , vol.10 , pp. 419-429
    • Saberi, M.1
  • 23
    • 84868026167 scopus 로고    scopus 로고
    • Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages
    • Orr, J. S. et al. Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. Diabetes 61, 2718-2727 (2012).
    • (2012) Diabetes , vol.61 , pp. 2718-2727
    • Orr, J.S.1
  • 24
    • 0034019920 scopus 로고    scopus 로고
    • Expression of Cre recombinase in mouse oocytes: A means to study maternal effect genes
    • DOI 10.1002/(SICI)1526-968X(200002) 26:2<110::AID-GENE2>3.0.CO;2-8
    • de Vries, W. N. et al. Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes. Genesis 26, 110-112 (2000). (Pubitemid 30158090)
    • (2000) Genesis , vol.26 , Issue.2 , pp. 110-112
    • De Vries, W.N.1    Binns, L.T.2    Fancher, K.S.3    Dean, J.4    Moore, R.5    Kemler, R.6    Knowles, B.B.7
  • 25
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide evidence for TLR4 as the Lps gene product
    • Hoshino, K. et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162, 3749-3752 (1999). (Pubitemid 29314747)
    • (1999) Journal of Immunology , vol.162 , Issue.7 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6    Takeda, K.7    Akira, S.8
  • 26
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • DOI 10.1016/S1074-7613(00)80119-3
    • Takeuchi, O. et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-451 (1999). (Pubitemid 29504199)
    • (1999) Immunity , vol.11 , Issue.4 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 27
    • 84896341078 scopus 로고    scopus 로고
    • The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling
    • Uchimura, K. et al. The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling. Nat. Commun. 5, 3428 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 3428
    • Uchimura, K.1
  • 28
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • DOI 10.1023/A:1008942828960
    • Clausen, B. E., Burkhardt, C., Reith, W., Renkawitz, R. & Forster, I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8, 265-277 (1999). (Pubitemid 29523965)
    • (1999) Transgenic Research , vol.8 , Issue.4 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Forster, I.5
  • 29
    • 84865108051 scopus 로고    scopus 로고
    • Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance
    • Reynolds, C. M. et al. Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance. Mol. Nutr. Food Res. 56, 1212-1222 (2012).
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 1212-1222
    • Reynolds, C.M.1
  • 30
    • 65249083921 scopus 로고    scopus 로고
    • B cells from periodontal disease patients express surface toll-like receptor 4
    • Shin, H. et al. B cells from periodontal disease patients express surface Toll-like receptor 4. J. Leukoc. Biol. 85, 648-655 (2009).
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 648-655
    • Shin, H.1
  • 31
    • 78650077214 scopus 로고    scopus 로고
    • Systemic toll-like receptor ligands modify B-cell responses in human inflammatory bowel disease
    • McDonnell, M. et al. Systemic Toll-like receptor ligands modify B-cell responses in human inflammatory bowel disease. Inflamm. Bowel Dis. 17, 298-307 (2011).
    • (2011) Inflamm. Bowel Dis. , vol.17 , pp. 298-307
    • McDonnell, M.1
  • 32
    • 0029243372 scopus 로고
    • The role of nitric oxide in kupffer cell-hepatocyte interactions
    • Harbrecht, B. G. & Billiar, T. R. The role of nitric oxide in Kupffer cell-hepatocyte interactions. Shock 3, 79-87 (1995).
    • (1995) Shock , vol.3 , pp. 79-87
    • Harbrecht, B.G.1    Billiar, T.R.2
  • 33
    • 34447116244 scopus 로고    scopus 로고
    • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
    • Chen, C. J. et al. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat. Med. 13, 851-856 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 851-856
    • Chen, C.J.1
  • 34
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • Samuel, V. T. & Shulman, G. I. Mechanisms for insulin resistance: common threads and missing links. Cell 148, 852-871 (2012).
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 35
    • 25644448266 scopus 로고    scopus 로고
    • Fat in the liver and insulin resistance
    • DOI 10.1080/07853890510037383
    • Yki-Jarvinen, H. Fat in the liver and insulin resistance. Ann. Med. 37, 347-356 (2005). (Pubitemid 41379841)
    • (2005) Annals of Medicine , vol.37 , Issue.5 , pp. 347-356
    • Yki-Jarvinen, H.1
  • 36
    • 79955487247 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
    • Holland, W. L. et al. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J. Clin. Invest. 121, 1858-1870 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 1858-1870
    • Holland, W.L.1
  • 37
    • 84881098074 scopus 로고    scopus 로고
    • Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signalling and ceramide synthesis in vivo
    • Galbo, T. et al. Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signalling and ceramide synthesis in vivo. Proc. Natl Acad. Sci. USA 110, 12780-12785 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 12780-12785
    • Galbo, T.1
  • 38
    • 77956335194 scopus 로고    scopus 로고
    • Interleukin-6 signalling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action
    • Wunderlich, F. T. et al. Interleukin-6 signalling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action. Cell Metab. 12, 237-249 (2010).
    • (2010) Cell Metab. , vol.12 , pp. 237-249
    • Wunderlich, F.T.1
  • 39
    • 78049428301 scopus 로고    scopus 로고
    • A liver-derived secretory protein, selenoprotein P, causes insulin resistance
    • Misu, H. et al. A liver-derived secretory protein, selenoprotein P, causes insulin resistance. Cell Metab. 12, 483-495 (2010).
    • (2010) Cell Metab. , vol.12 , pp. 483-495
    • Misu, H.1
  • 40
    • 84874241199 scopus 로고    scopus 로고
    • Liver-derived systemic factors drive beta cell hyperplasia in insulin-resistant states
    • El Ouaamari, A. et al. Liver-derived systemic factors drive beta cell hyperplasia in insulin-resistant states. Cell Rep. 3, 401-410 (2013).
    • (2013) Cell Rep. , vol.3 , pp. 401-410
    • El Ouaamari, A.1
  • 41
    • 37549013749 scopus 로고    scopus 로고
    • Inhibition or deletion of the lipopolysaccharide receptor toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle
    • Radin, M. S., Sinha, S., Bhatt, B. A., Dedousis, N. & O'Doherty, R. M. Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle. Diabetologia 51, 336-346 (2008).
    • (2008) Diabetologia , vol.51 , pp. 336-346
    • Radin, M.S.1    Sinha, S.2    Bhatt, B.A.3    Dedousis, N.4    O'Doherty, R.M.5
  • 45
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • Lee, E. C. et al. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73, 56-65 (2001).
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1


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