Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo

Respiratory Research

Volumn 15, Issue 1, 2014, Pages

  Luo, Fayong ^a   Zhuang, Yan ^a   Sides, Mark D ^a   Sanchez, Cecilia G ^a   Shan, Bin ^a   White, Eric S ^b   Lasky, Joseph A ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Arsenic trioxide; Bleomycin; IPF; PML; Pulmonary fibrosis; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ARSENIC TRIOXIDE; BETA ACTIN; COLLAGEN TYPE 1; FIBRONECTIN; MESSENGER RNA; PROMYELOCYTIC LEUKEMIA PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; BLEOMYCIN; ORGANOARSENIC DERIVATIVE; OXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MYOFIBROBLAST; NONHUMAN; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL TRANSDIFFERENTIATION; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; LUNG; LUNG FIBROSIS; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ARSENICALS; BLEOMYCIN; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; FIBROBLASTS; HUMANS; LUNG; MICE; MICE, INBRED C57BL; MYOFIBROBLASTS; OXIDES; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84900429738     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-15-51     Document Type: Article

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