Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells

Cell Death and Differentiation

Volumn 17, Issue 12, 2010, Pages 1867-1881

  Smith, D M ^a   Patel, S ^a   Raffoul, F ^a   Haller, E ^a   Mills, G B ^b   Nanjundan, M ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

arsenic trioxide (As 2O3); autophagy; ecotropic viral integration site 1 (EVI1); ovarian cancer; SnoN SkiL; transforming growth factor (TGF )

Indexed keywords

ACETYLCYSTEINE; ARSENIC TRIOXIDE; BECLIN 1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; SKI RELATED NOVEL TRANSFORMING GROWTH FACTOR BETA; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OVARY CANCER; PHAGOSOME; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ACETYLCYSTEINE; APOPTOSIS REGULATORY PROTEINS; ARSENICALS; AUTOPHAGY; CARCINOMA; CELL LINE, TUMOR; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OVARIAN NEOPLASMS; OXIDES; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN-ACTIVATING ENZYMES;

EID: 78349311964     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.53     Document Type: Article

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