Transforming growth factor β1 induction of tissue inhibitor of metalloProteinases 3 in articular chondrocytes is mediated by reactive oxygen species

Free Radical Biology and Medicine

Volumn 37, Issue 2, 2004, Pages 196-207

  Li, Wen Qing ^a   Qureshi, Hamid Yaqoob ^a   Liacini, Abdelhamid ^a   Dehnade, Faramaze ^a   Zafarullah, Muhammad ^a  

^a NOTRE DAME HOSPITAL   (Canada)

Author keywords

Chondrocytes; Free radicals; Growth factor; Metalloproteinase inhibitors; Redox sensitivity; Smad

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; ASCORBIC ACID; EBSELEN; HYDROGEN PEROXIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SMAD2 PROTEIN; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS;

ACETYLCYSTEINE; ANIMALS; ASCORBIC ACID; AZOLES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHONDROCYTES; CULTURE MEDIA, SERUM-FREE; CYCLOHEXIMIDE; DNA-BINDING PROTEINS; DOWN-REGULATION; FREE RADICALS; GROWTH SUBSTANCES; HUMANS; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OLIGONUCLEOTIDES, ANTISENSE; ORGANOSELENIUM COMPOUNDS; OXIDATION-REDUCTION; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RNA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SPECIES SPECIFICITY; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TRANS-ACTIVATORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

BOVINAE;

EID: 2942564047     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.04.028     Document Type: Article

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