메뉴 건너뛰기




Volumn 6, Issue 2, 2014, Pages 179-191

DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/β-catenin signaling pathway genes

Author keywords

CpG; DNA repair genes; Infinium Human Methylation 450 BeadChip; methylation status; sporadic colorectal cancer; Wnt catenin signaling pathway

Indexed keywords

BETA CATENIN; BIOLOGICAL MARKER; CASPASE 8; CYCLIN H; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; MESSENGER RNA; SMAD2 PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 1; WNT PROTEIN; WNT2 PROTEIN; WNT3A PROTEIN; WNT6 PROTEIN; DCLRE1C PROTEIN, HUMAN; GLYPICAN; GPC6 PROTEIN, HUMAN; NUCLEAR PROTEIN;

EID: 84900412412     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.14.7     Document Type: Article
Times cited : (55)

References (51)
  • 2
    • 63749119744 scopus 로고    scopus 로고
    • Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic
    • Polakova V, Pardini B, Naccarati A et al. Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic. Hum. Mutat.30(4), 661-668 (2009).
    • (2009) Hum. Mutat , vol.30 , Issue.4 , pp. 661-668
    • Polakova, V.1    Pardini, B.2    Naccarati, A.3
  • 3
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • DOI 10.1111/j.1365-2559.2006.02549.x
    • Jass JR. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology50(1), 113-130 (2007). (Pubitemid 44953403)
    • (2007) Histopathology , vol.50 , Issue.1 , pp. 113-130
    • Jass, J.R.1
  • 4
    • 84888012302 scopus 로고    scopus 로고
    • A study of genomic instability in early preneoplastic colonic lesions
    • Beggs AD, Domingo E, Abulafi M, Hodgson SV, Tomlinson IP. A study of genomic instability in early preneoplastic colonic lesions. Oncogene.32(46), 5333-5337 (2013).
    • (2013) Oncogene , vol.32 , Issue.46 , pp. 5333-5337
    • Beggs, A.D.1    Domingo, E.2    Abulafi, M.3    Hodgson, S.V.4    Tomlinson, I.P.5
  • 5
    • 79751531115 scopus 로고    scopus 로고
    • The American College of Gastroenterology Emily Couric Lecture-the adenoma-carcinoma sequence revisited: Has the era of genetic tailoring finally arrived?
    • Ahnen DJ. The American College of Gastroenterology Emily Couric Lecture-the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived? Am. J. Gastroenterol.106(2), 190-198 (2011).
    • (2011) Am. J. Gastroenterol , vol.106 , Issue.2 , pp. 190-198
    • Ahnen, D.J.1
  • 6
    • 5444255150 scopus 로고    scopus 로고
    • The epigenetics of cancer etiology
    • DOI 10.1016/j.semcancer.2004.06.005, PII S1044579X04000483
    • Feinberg AP. The epigenetics of cancer etiology. Semin. Cancer Biol.14(6), 427-432 (2004). (Pubitemid 39360990)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.6 , pp. 427-432
    • Feinberg, A.P.1
  • 7
    • 0035522894 scopus 로고    scopus 로고
    • Two genetic hits (more or less) to cancer
    • Knudson AG. Two genetic hits (more or less) to cancer. Nat. Rev. Cancer1(2), 157-162 (2001). (Pubitemid 33741891)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.2 , pp. 157-162
    • Knudson, A.G.1
  • 8
    • 58149337352 scopus 로고    scopus 로고
    • APC and the three-hit hypothesis
    • Segditsas S, Rowan AJ, Howarth K et al. APC and the three-hit hypothesis. Oncogene28(1), 146-155 (2009).
    • (2009) Oncogene , vol.28 , Issue.1 , pp. 146-155
    • Segditsas, S.1    Rowan, A.J.2    Howarth, K.3
  • 9
    • 33847355677 scopus 로고    scopus 로고
    • DNA methylation in colorectal cancer - Impact on screening and therapy monitoring modalities?
    • Epigenetic Markers
    • Zitt M, Müller HM. DNA methylation in colorectal cancer-impact on screening and therapy monitoring modalities? Dis. Markers.23(1-2), 51-71 (2007). (Pubitemid 46333641)
    • (2007) Disease Markers , vol.23 , Issue.1-2 , pp. 51-71
    • Zitt, M.1    Zitt, M.2    Muller, H.M.3
  • 10
    • 84883520928 scopus 로고    scopus 로고
    • Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips
    • Naumov VA, Generozov EV, Zaharjevskaya NB et al. Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics.8(9), 921-934 (2013).
    • (2013) Epigenetics , vol.8 , Issue.9 , pp. 921-934
    • Naumov, V.A.1    Generozov, E.V.2    Zaharjevskaya, N.B.3
  • 12
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Network CGA. Comprehensive molecular characterization of human colon and rectal cancer. Nature.487(7407), 330-337 (2012).
    • (2012) Nature , vol.487 , Issue.7407 , pp. 330-337
    • Network, C.G.A.1
  • 13
    • 84856549042 scopus 로고    scopus 로고
    • Genome-scale analysis of aberrant DNA methylation in colorectal cancer
    • Hinoue T, Weisenberger DJ, Lange CP et al. Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Res.22(2), 271-282 (2012).
    • (2012) Genome Res , vol.22 , Issue.2 , pp. 271-282
    • Hinoue, T.1    Weisenberger, D.J.2    Lange, C.P.3
  • 14
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores
    • Irizarry R, Ladd-Acosta C, Wen B et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat. Genet.41(2), 178-186 (2009).
    • (2009) Nat. Genet , vol.41 , Issue.2 , pp. 178-186
    • Irizarry, R.1    Ladd-Acosta, C.2    Wen, B.3
  • 15
    • 84868581612 scopus 로고    scopus 로고
    • Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas
    • Slyskova J, Korenkova V, Collins AR et al. Functional, genetic, and epigenetic aspects of base and nucleotide excision repair in colorectal carcinomas. Clin. Cancer Res.18(21), 5878-5887 (2012).
    • (2012) Clin. Cancer Res , vol.18 , Issue.21 , pp. 5878-5887
    • Slyskova, J.1    Korenkova, V.2    Collins, A.R.3
  • 16
    • 79958754527 scopus 로고    scopus 로고
    • Validation of a DNA methylation microarray for 450, 000 CpG sites in the human genome
    • Sandoval J, Heyn HA, Moran S et al. Validation of a DNA methylation microarray for 450, 000 CpG sites in the human genome. Epigenetics6(6), 692-702 (2011).
    • (2011) Epigenetics , vol.6 , Issue.6 , pp. 692-702
    • Sandoval, J.1    Heyn, H.A.2    Moran, S.3
  • 17
    • 80053304450 scopus 로고    scopus 로고
    • High density DNA methylation array with single CpG site resolution
    • Bibikova M, Barnes B, Tsan C et al. High density DNA methylation array with single CpG site resolution. Genomics98(4), 288-295 (2011).
    • (2011) Genomics , vol.98 , Issue.4 , pp. 288-295
    • Bibikova, M.1    Barnes, B.2    Tsan, C.3
  • 19
    • 84900463804 scopus 로고    scopus 로고
    • Human DNA repair genes
    • Human DNA repair genes. http://sciencepark.mdanderson.org/labs/wood/dna- repair-genes.html
  • 20
    • 30344454706 scopus 로고    scopus 로고
    • A genotype calling algorithm for affymetrix SNP arrays
    • DOI 10.1093/bioinformatics/bti741
    • Rabbee N, Speed TP. A genotype calling algorithm for affymetrix SNP arrays. Bioinformatics22(1), 7-12 (2006). (Pubitemid 43057002)
    • (2006) Bioinformatics , vol.22 , Issue.1 , pp. 7-12
    • Rabbee, N.1    Speed, T.P.2
  • 21
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based DNA copy number data
    • DOI 10.1093/biostatistics/kxh008
    • Olshen AB, Venkatraman ES, Lucito R, Wigler M. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics5(4), 557-572 (2004). (Pubitemid 41180205)
    • (2004) Biostatistics , vol.5 , Issue.4 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3    Wigler, M.4
  • 22
    • 80054799330 scopus 로고    scopus 로고
    • Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
    • Rasmussen M, Sundstrom M, Kultima HG et al. Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity. Genome Biol. 12(10), R108 (2011).
    • (2011) Genome Biol. , vol.12 , Issue.10
    • Rasmussen, M.1    Sundstrom, M.2    Kultima, H.G.3
  • 23
    • 79951831756 scopus 로고    scopus 로고
    • Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy
    • Uddin S, Ahmed M, Hussain A et al. Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy. Am J. Pathol.178(2), 537-547 (2011).
    • (2011) Am J. Pathol , vol.178 , Issue.2 , pp. 537-547
    • Uddin, S.1    Ahmed, M.2    Hussain, A.3
  • 24
    • 84900397645 scopus 로고    scopus 로고
    • NCBI
    • NCBI. www.ncbi.nlm.nih.gov/geo/geo2r
  • 25
    • 84863230488 scopus 로고    scopus 로고
    • IMA: An R package for high-throughput analysis of Illumina's 450K Infinium methylation data
    • Wang D, Yan L, Hu Q et al. IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data. Bioinformatics28(5), 729-730 (2012).
    • (2012) Bioinformatics , vol.28 , Issue.5 , pp. 729-730
    • Wang, D.1    Yan, L.2
  • 26
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol.3, (2004). Article3
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3
    • Smyth, G.K.1
  • 27
    • 79952532412 scopus 로고    scopus 로고
    • Cancer epigenetics: Linking basic biology to clinical medicine
    • Tsai HC, Baylin SB. Cancer epigenetics: linking basic biology to clinical medicine. Cell Res. 21(3), 502-517 (2011).
    • (2011) Cell Res. , vol.21 , Issue.3 , pp. 502-517
    • Tsai, H.C.1    Baylin, S.B.2
  • 28
    • 84880063991 scopus 로고    scopus 로고
    • DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer
    • Carmona FJ, Azuara D, Berenguer-Llergo A et al. DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer. Cancer Prev. Res. (Phila.)6(7), 656-665 (2013).
    • (2013) Cancer Prev. Res. (Phila.) , vol.6 , Issue.7 , pp. 656-665
    • Carmona, F.J.1    Azuara, D.2    Berenguer-Llergo, A.3
  • 30
    • 84893647957 scopus 로고    scopus 로고
    • Global alterations of DNA methylation in cholangiocarcinoma targets the Wnt signaling pathway
    • Goeppert B, Konermann C, Schmidt CR et al. Global alterations of DNA methylation in cholangiocarcinoma targets the Wnt signaling pathway. Hepatology59(2), 544-554 (2014).
    • (2014) Hepatology , vol.59 , Issue.2 , pp. 544-554
    • Goeppert, B.1    Konermann, C.2    Schmidt, C.R.3
  • 31
    • 84890128817 scopus 로고    scopus 로고
    • The low-abundance transcriptome reveals novel biomarkers, specific intracellular pathways and targetable genes associated with advanced gastric cancer
    • Bizama C, Benavente F, Salvatierra E et al. The low-abundance transcriptome reveals novel biomarkers, specific intracellular pathways and targetable genes associated with advanced gastric cancer. Int. J. Cancer134(4), 755-764 (2014).
    • (2014) Int. J. Cancer , vol.V134 , Issue.4 , pp. 755-764
    • Bizama, C.1    Benavente, F.2    Salvatierra, E.3
  • 33
    • 84873683996 scopus 로고    scopus 로고
    • DNA methylation of the p14ARF RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients
    • Nilsson TK, Löf-Öhlin ZM, Sun XF. DNA methylation of the p14ARF, RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients. Int. J. Oncol.42(1), 127-133 (2013).
    • (2013) Int. J. Oncol , vol.42 , Issue.1 , pp. 127-133
    • Nilsson, T.K.1    Löf-Öhlin, Z.M.2    Sun, X.F.3
  • 34
    • 33645299092 scopus 로고    scopus 로고
    • Caspases at the crossroads of immune-cell life and death
    • Siegel RM. Caspases at the crossroads of immune-cell life and death. Nat. Rev. Immunol.6(4), 308-317 (2006).
    • (2006) Nat. Rev. Immunol , vol.6 , Issue.4 , pp. 308-317
    • Siegel, R.M.1
  • 36
    • 12444281807 scopus 로고    scopus 로고
    • Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225-1226delTG in hepatocellular carcinomas
    • DOI 10.1038/sj.onc.1208244
    • Soung YH, Lee JW, Kim SY et al. Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225-1226delTG in hepatocellular carcinomas. Oncogene24(1), 141-147 (2005). (Pubitemid 40143873)
    • (2005) Oncogene , vol.24 , Issue.1 , pp. 141-147
    • Soung, Y.H.1    Lee, J.W.2    Kim, S.Y.3    Sung, Y.J.4    Park, W.S.5    Nam, S.W.6    Kim, S.H.7    Lee, J.Y.8    Yoo, N.J.9    Lee, S.H.10
  • 37
    • 77649169154 scopus 로고    scopus 로고
    • Epigenetic methylation and expression of caspase 8 and survivin in hepatocellular carcinoma
    • Cho S, Lee JH, Cho SB et al. Epigenetic methylation and expression of caspase 8 and survivin in hepatocellular carcinoma. Pathol. Int.60(3), 203-211 (2010).
    • (2010) Pathol. Int. , vol.60 , Issue.3 , pp. 203-211
    • Cho, S.1    Lee, J.H.2    Cho, S.B.3
  • 38
    • 84861792883 scopus 로고    scopus 로고
    • MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma
    • Skiriute D, Vaitkiene P, Saferis V et al. MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma. BMC Cancer12, 218 (2012).
    • (2012) BMC Cancer , vol.12 , pp. 218
    • Skiriute, D.1    Vaitkiene, P.2    Saferis, V.3
  • 39
    • 77349089525 scopus 로고    scopus 로고
    • Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
    • Wu Y, Alvarez M, Slamon DJ, Koeffler P, Vadgama JV. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer10, 32 (2010).
    • (2010) BMC Cancer , vol.10 , pp. 32
    • Wu, Y.1    Alvarez, M.2    Slamon, D.J.3    Koeffler, P.4    Vadgama, J.V.5
  • 40
    • 84888810517 scopus 로고    scopus 로고
    • Recurrent patterns of DNA methylation in the ZNF154,CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines
    • Sánchez-Vega F, Gotea V, Petrykowska HM et al. Recurrent patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines. Epigenetics8(12), 1355-1372 (2013).
    • (2013) Epigenetics , vol.8 , Issue.12 , pp. 1355-1372
    • Sánchez-Vega, F.1    Gotea, V.2    Petrykowska, H.M.3
  • 41
    • 84855201521 scopus 로고    scopus 로고
    • Novel mutations of endothelin-B receptor gene in Pakistani patients with Waardenburg syndrome
    • Jabeen R, Babar ME, Ahmad J, Awan AR. Novel mutations of endothelin-B receptor gene in Pakistani patients with Waardenburg syndrome. Mol. Biol. Rep.39(1), 785-788 (2012).
    • (2012) Mol. Biol. Rep. , vol.39 , Issue.1 , pp. 785-788
    • Jabeen, R.1    Babar, M.E.2    Ahmad, J.3    Awan, A.R.4
  • 43
    • 84864069479 scopus 로고    scopus 로고
    • Quantitative analysis of promoter methylation of the EDNRB gene in gastric cancer
    • Tao K, Wu C, Wu K et al. Quantitative analysis of promoter methylation of the EDNRB gene in gastric cancer. Med. Oncol.29(1), 107-112 (2012).
    • (2012) Med. Oncol , vol.29 , Issue.1 , pp. 107-112
    • Tao, K.1    Wu, C.2    Wu, K.3
  • 44
    • 33744475913 scopus 로고    scopus 로고
    • Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan
    • Hsu LS, Lee HC, Chau GY, Yin PH, Chi CW, Lui WY. Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan. Oncol. Rep.15(2), 507-511 (2006).
    • (2006) Oncol. Rep. , vol.15 , Issue.2 , pp. 507-511
    • Hsu, L.S.1    Lee, H.C.2    Chau, G.Y.3    Yin, P.H.4    Chi, C.W.5    Lui, W.Y.6
  • 46
    • 77949529656 scopus 로고    scopus 로고
    • Allelic imbalance at 13q31 is associated with reduced GPC6 in Chinese with sporadic retinoblastoma
    • Lau CS, Yu CB, Wong HK et al. Allelic imbalance at 13q31 is associated with reduced GPC6 in Chinese with sporadic retinoblastoma. Br. J. Ophthalmol.94(3), 357-362 (2010).
    • (2010) Br. J. Ophthalmol. , vol.94 , Issue.3 , pp. 357-362
    • Lau, C.S.1    Yu, C.B.2    Wong, H.K.3
  • 47
    • 80054942842 scopus 로고    scopus 로고
    • NFAT promotes carcinoma invasive migration through glypican-6
    • Yiu GK, Kaunisto A, Chin YR, Toker A. NFAT promotes carcinoma invasive migration through glypican-6. Biochem. J.440(1), 157-166 (2011).
    • (2011) Biochem. J. , vol.440 , Issue.1 , pp. 157-166
    • Yiu, G.K.1    Kaunisto, A.2    Chin, Y.R.3    Toker, A.4
  • 48
    • 84872510974 scopus 로고    scopus 로고
    • SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer
    • Fleming NI, Jorissen RN, Mouradov D et al. SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res.73(2), 725-735 (2013).
    • (2013) Cancer Res. , vol.73 , Issue.2 , pp. 725-735
    • Fleming, N.I.1    Jorissen, R.N.2    Mouradov, D.3
  • 49
    • 76249084838 scopus 로고    scopus 로고
    • Smad signaling is required to maintain epigenetic silencing during breast cancer progression
    • Papageorgis P, Lambert AW, Ozturk S et al. Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Res.70(3), 968-978 (2010).
    • (2010) Cancer Res , vol.70 , Issue.3 , pp. 968-978
    • Papageorgis, P.1    Lambert, A.W.2    Ozturk, S.3
  • 50
    • 84884759753 scopus 로고    scopus 로고
    • Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer
    • Kulis M, Queirós AC, Beekman R, Martín-Subero JI. Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer. Biochim. Biophys. Acta1829(11), 1161-1174 (2013).
    • (2013) Biochim. Biophys. Acta , vol.1829 , Issue.11 , pp. 1161-1174
    • Kulis, M.1    Queirós, A.C.2    Beekman, R.3    Martín-Subero, J.I.4
  • 51
    • 84884898098 scopus 로고    scopus 로고
    • Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
    • Nordlund J, Bäcklin CL, Wahlberg P et al. Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia. Genome Biol.14(9), r105 (2013).
    • (2013) Genome Biol , vol.14 , Issue.9
    • Nordlund, J.1    Bäcklin, C.L.2    Wahlberg, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.