Glypicans

Genome Biology

Volumn 9, Issue 5, 2009, Pages

  Filmus, Jorge ^a   Capurro, Mariana ^a   Rast, Jonathan ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; FRIZZLED PROTEIN; GLYPICAN; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; ANIMAL; CELL MEMBRANE; CHEMISTRY; GENETICS; MOLECULAR EVOLUTION; PHYSIOLOGY;

ERINACEIDAE; EUMETAZOA; MAMMALIA;

ANIMALS; CELL MEMBRANE; EVOLUTION, MOLECULAR; GLYPICANS; HUMANS;

EID: 66249084507     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2008-9-5-224     Document Type: Review

References (48)

1. Filmus J Selleck SB Glypicans: Proteoglycans with a surprise. J Clin Invest 2001, 108:497-501. 209407 11518720
2. Fico A Maina F Dono R Fine-tuning of cell signalling by glypicans. Cell Mol Life Sci 18087675
3. Ensembl http://www.ensembl.org/index.html
4. Veugelers M De Cat B Ceulemans H Bruystens AM Coomans C Durr J Vermeesch J Marynen P David G Glypican-6, a new member of the glypican family of cell surface proteoglycans. J Biol Chem 1999, 274:26968-26977. 10.1074/ jbc.274.38.26968 10480909
5. Topczewsky J Sepich DS Myers DC Walker C Amores A Lele Z Hammerschmidt M Postlethwait J Solnica-Krezel L The zebrafish glypican Knypek controls cell polarity during gastrulation movements of convergent extension. Dev Cell 2001, 1:251-264. 10.1016/S1534-5807(01)00005-3 11702784
6. Eugster C Panakova D Mahmoud A Eaton S Lipoprotein-heparan sulfate interactions in the Hh pathway. Dev Cell 2007, 13:57-71. 10.1016/ j.devcel.2007.04.019 17609110
7. De Cat B Muyldermans SY Coomans C Degeest G Vander-schueren B Creemers J Biemar F Peers B David G Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements. J Cell Biol 2003, 163:625-635. 2173654 14610063 10.1083/jcb.200302152
8. Hagihara K Watanabe K Chun J Yamaguchi Y Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells. Dev Dyn 2000, 219:353-367. 10.1002/ 1097-0177(2000)9999:9999<::AID-DVDY1059>3.0.CO;2-# 11066092
9. Watanabe K Yamada H Yamaguchi Y K-glypican: A novel GPI-linked heparan sulfate proteoglycan that is highly expressed in developing brain and kidney. J Cell Biol 1995, 130:1207-1218. 2120559 7657705 10.1083/ jcb.130.5.1207
10. Capurro MI Shi W Sandal S Filmus J Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma. J Biol Chem 2005, 280:41201-41206. 10.1074/jbc.M507004200 16227623
11. Saunders S Paine-Saunders S Lander AD Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. Dev Biol 1997, 190:78-93. 10.1006/dbio.1997.8690 9331333
12. Mayor S Riezman H Sorting GPI-anchored proteins. Nat Rev Mol Cell Biol 2004, 5:110-120. 10.1038/nrm1309 15040444
13. Hancock JF Lipid rafts: Contentious only from simplistic standpoints. Nat Rev Mol Cell Biol 2006, 7:456-462. 10.1038/nrm1925 16625153
14. Mertens G Schueren Van den B Berghe Van Den H David G Heparan sulfate expression in polarized epithelial cells: The apical sorting of glypican (GPI-anchored proteoglycan) is inversely related to its heparan sulfate content. J Cell Biol 1996, 132:487-497. 2120721 8636224 10.1083/ jcb.132.3.487
15. Lin X Perrimon N Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signaling. Nature 1999, 400:281-284. 10.1038/22343 10421372
16. Song HH Shi W Xiang Y Filmus J The loss of Glypican-3 induces alterations in Wnt signaling. J Biol Chem 2005, 280:2116-2125. 10.1074/ jbc.M410090200 15537637
17. Yan D Lin X Drosophila glypican Dally-like acts in FGF-receiving cells to modulate FGF signaling during tracheal morphogenesis. Dev Biol 2007, 312:203-216. 2151973 17959166 10.1016/j.ydbio.2007.09.015
18. Ohkawara B Yamamoto TS Tada M Ueno N Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 2003, 130:2129-2138. 10.1242/dev.00435 12668627
19. Capurro MI Xu P Shi W Li F Jia A Filmus J Glypican-3 inhibits hedgehog signaling during development by competing with Patched for Hedgehog binding. Dev Cell 2008, 14:700-711. 10.1016/j.devcel.2008.03.006 18477453
20. Desbordes SC Sanson B The glypican Dally-like is required for hedgehog signalling in the embryonic epidermis of Drosophila. Development 2003, 130:6245-6255. 10.1242/dev.00874 14602684
21. Jackson SM Nakato H Sugiura M Jannuzi A Oakes R Kaluza V Golden C Selleck SB dally, a Drosophila glypican, controls celular responses to the TGF-beta-related morphogen Dpp. Development 1997, 124:4113-4120. 9374407
22. Capurro M Xiang YY Lobe C Filmus J Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res 2005, 65:6245-6254. 10.1158/0008-5472.CAN-04-4244 16024626
23. Johnson KG Tenney AP Ghose A Duckworth AM Higashi ME Parfitt K Marcu O Heslip TR Marsh JL Schwarz TL Flanagan JG Van Vactor D The HSPGs syndecan and Dallylike bind the receptor phophatase LAR and exert distinct effects on synaptic development. Neuron 2006, 49:517-531. 10.1016/j.neuron.2006.01.026 16476662
24. Fransson LA Glypicans. Int J Biochem Cell Biol 2003, 35:125-129. 10.1016/ S1357-2725(02)00095-X 12479862
25. Kreuger J Perez L Giraldez AJ Cohen SM Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev Cell 2004, 7:503-512. 10.1016/j.devcel.2004.08.005 15469839
26. Traister A Shi W Filmus J Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface. Biochem J 2008, 410:503-511. 10.1042/BJ20070511
27. Fujise M Takeo S Kamimura K Matsuo T Aigaki T Izumi S Nakato H Dally regulates Dpp morphogen gradient formation in the Drosophila wing. Development 2003, 130:1515-1522. 10.1242/dev.00379 12620978
28. Han C Belenkaya TY Wang B Lin X Drosophila glypicans control the cell-to-cell movement of hedgehog by a dynamin-independent process. Development 2004, 131:601-611. 10.1242/dev.00958 14729575
29. Kirkpatrick CA Dimitroff BD Rawson JM Selleck SB Spatial regulation of wingless morphogen distribution and signaling by Dally-like protein. Dev Cell 2004, 7:513-523. 10.1016/j.devcel.2004.08.004 15469840
30. Belenkaya TY Han C Yan D Opoka RJ Khodoun M Liu H Lin X Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell 2004, 119:231-244. 10.1016/j.cell.2004.09.031 15479640
31. Han C Yan D Belenkaya TY Lin X Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disk. Development 2005, 132:667-679. 10.1242/dev.01636 15647319
32. Akiyama T Kamimura K Firkus C Takeo S Shimmi O Nakato H Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface. Dev Biol 2008, 313:408-419. 10.1016/j.ydbio.2007.10.035 18054902
33. Willnow TE Hammes A Eaton S Lipoproteins and their receptors in embryonic development: More than cholesterol clearance. Development 2007, 134:3239-3249. 10.1242/dev.004408 17720693
34. Capurro M Wanless IR Sherman M Deboer G Shi W Miyoshi E Filmus J Glypican-3: A novel serum and histochemical marker for hepatocellular carcinoma. Gastroenterology 2003, 125:81-90. 10.1016/ S0016-5085(03)00689-9
35. Ligato S Mandich D Cartun RW Utility of glypican-3 in differentiating hepatocellular carcinoma from other primary and metastatic lesions in FNA of the liver: An imunocytochemical study. Modern Pathol 2008, 21:626-631. 10.1038/modpathol.2008.26
36. Ai X Do AT Lozynska O Kusche-Gullberg M Lindhal U Emerson CP QSulf1 remodels the 6-O sulfation states of cell surface proteoglycans to promote Wnt signaling. J Cell Biol 2003, 162:341-351. 2172803 12860968 10.1083/jcb.200212083
37. Lum L Yao S Mozer B Rovescalli A Von Kessler D Nirenberg M Beachy PA Identification of hedgehog pathway components by RNAi in Drosophila cultured cells. Science 2003, 299:2039-2045. 10.1126/science.1081403 12663920
38. Song HH Shi W Filmus J OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2. J Biol Chem 1997, 272:7574-7577. 10.1074/jbc.272.12.7574 9065409
39. Kirkpatrick CA Knox SM Staatz WD Fox B Lercher DM Selleck SB The function of a Drosophila glypican does not depend entirely on heparan sulfate modification. Dev Biol 2006, 300:570-582. 10.1016/ j.ydbio.2006.09.011 17055473
40. David G Lories V Decock B Marynen P Cassiman J Berghe Van Den H Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts. J Cell Biol 1990, 111:3165-3176. 2116352 2148568 10.1083/jcb.111.6.3165
41. Stipp CS Litwac ED Lander AD Cerebroglycan: An integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation. J Cell Biol 1994, 124:149-160. 2119891 8294498 10.1083/jcb.124.1.149
42. Filmus J Church J Buick RN Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine. Mol Cell Biol 1988, 8:4243-4249. 365496 3185547
43. Veugelers M Vermeesch J Reekmans G Steinfeld R Marynen P David G Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family. Genomics 1997, 40:24-30. 10.1006/geno.1996.4518 9070915
44. Paine-Saunders S Viviano BL Saunders S GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13. Genomics 1999, 57:455-458. 10.1006/geno.1999.5793 10329016
45. Nakato H Futch TA Selleck SB The division abnormally delayed (dally) gene: A putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila. Development 1995, 121:3687-3702. 8582281
46. Baeg GH Lin X Khare N Baumgartner S Perrimon N Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 2001, 128:87-94. 11092814
47. Tamura K Dudley J Nei M Kumar S MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007, 24:1596-1599. 10.1093/molbev/msm092 17488738
48. Sea Urchin Genome Project http://www.hgsc.bcm.tmc.edu/projects/seaurchin