메뉴 건너뛰기




Volumn 71, Issue 10, 2014, Pages 1907-1916

Remodeling and dedifferentiation of adult cardiomyocytes during disease and regeneration

Author keywords

Dilative cardiomyopathy; Hibernating myocardium; Hypertrophy; Hypoxia inducible transcription factor; Myocardial infarction; Myocardial remodeling; Myoglobin; Oncostatin M

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ONCOSTATIN M;

EID: 84900341024     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1535-6     Document Type: Review
Times cited : (64)

References (66)
  • 1
    • 77955980416 scopus 로고    scopus 로고
    • Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation
    • 10.1097/FJC.0b013e3181e74a14 20505524
    • Lopaschuk GD, Jaswal JS (2010) Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation. J Cardiovasc Pharmacol 56(2):130-140. doi: 10.1097/FJC.0b013e3181e74a14
    • (2010) J Cardiovasc Pharmacol , vol.56 , Issue.2 , pp. 130-140
    • Lopaschuk, G.D.1    Jaswal, J.S.2
  • 2
    • 84864929483 scopus 로고    scopus 로고
    • Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response
    • 10.1093/nar/gks301 3413112 22508755
    • Pohjoismaki JL, Boettger T, Liu Z, Goffart S, Szibor M, Braun T (2012) Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response. Nucleic Acids Res 40(14):6595-6607. doi: 10.1093/nar/gks301
    • (2012) Nucleic Acids Res , vol.40 , Issue.14 , pp. 6595-6607
    • Pohjoismaki, J.L.1    Boettger, T.2    Liu, Z.3    Goffart, S.4    Szibor, M.5    Braun, T.6
  • 3
    • 84877759551 scopus 로고    scopus 로고
    • Postnatal cardiomyocyte growth and mitochondrial reorganization cause multiple changes in the proteome of human cardiomyocytes
    • 10.1039/c3mb25556e 23459711
    • Pohjoismaki JL, Kruger M, Al-Furoukh N, Lagerstedt A, Karhunen PJ, Braun T (2013) Postnatal cardiomyocyte growth and mitochondrial reorganization cause multiple changes in the proteome of human cardiomyocytes. Mol BioSyst. doi: 10.1039/c3mb25556e
    • (2013) Mol BioSyst
    • Pohjoismaki, J.L.1    Kruger, M.2    Al-Furoukh, N.3    Lagerstedt, A.4    Karhunen, P.J.5    Braun, T.6
  • 4
    • 35848955451 scopus 로고    scopus 로고
    • Return to the fetal gene program protects the stressed heart: A strong hypothesis
    • 10.1007/s10741-007-9034-1 17516164
    • Rajabi M, Kassiotis C, Razeghi P, Taegtmeyer H (2007) Return to the fetal gene program protects the stressed heart: a strong hypothesis. Heart Fail Rev 12(3-4):331-343. doi: 10.1007/s10741-007-9034-1
    • (2007) Heart Fail Rev , vol.12 , Issue.3-4 , pp. 331-343
    • Rajabi, M.1    Kassiotis, C.2    Razeghi, P.3    Taegtmeyer, H.4
  • 5
    • 0034162004 scopus 로고    scopus 로고
    • Cardiac remodeling-concepts and clinical implications: A consensus paper from an international forum on cardiac remodeling. Behalf of an international forum on cardiac remodeling
    • 10716457
    • Cohn JN, Ferrari R, Sharpe N (2000) Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an international forum on cardiac remodeling. J Am Coll Cardiol 35(3):569-582
    • (2000) J Am Coll Cardiol , vol.35 , Issue.3 , pp. 569-582
    • Cohn, J.N.1    Ferrari, R.2    Sharpe, N.3
  • 6
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • 10.1016/j.cell.2009.04.060 19632177
    • Bersell K, Arab S, Haring B, Kuhn B (2009) Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 138(2):257-270. doi: 10.1016/j.cell.2009.04.060
    • (2009) Cell , vol.138 , Issue.2 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3    Kuhn, B.4
  • 7
    • 18844383961 scopus 로고    scopus 로고
    • P38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes
    • 10.1101/gad.1306705 1132004 15870258
    • Engel FB, Schebesta M, Duong MT, Lu G, Ren S, Madwed JB, Jiang H, Wang Y, Keating MT (2005) p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev 19(10):1175-1187. doi: 10.1101/gad.1306705
    • (2005) Genes Dev , vol.19 , Issue.10 , pp. 1175-1187
    • Engel, F.B.1    Schebesta, M.2    Duong, M.T.3    Lu, G.4    Ren, S.5    Madwed, J.B.6    Jiang, H.7    Wang, Y.8    Keating, M.T.9
  • 9
    • 77649087980 scopus 로고    scopus 로고
    • Return to the fetal gene program: A suggested metabolic link to gene expression in the heart
    • 10.1111/j.1749-6632.2009.05100.x 3625436 20201903
    • Taegtmeyer H, Sen S, Vela D (2010) Return to the fetal gene program: a suggested metabolic link to gene expression in the heart. Ann N Y Acad Sci 1188:191-198. doi: 10.1111/j.1749-6632.2009.05100.x
    • (2010) Ann N y Acad Sci , vol.1188 , pp. 191-198
    • Taegtmeyer, H.1    Sen, S.2    Vela, D.3
  • 10
    • 77950200829 scopus 로고    scopus 로고
    • Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
    • 10.1038/nature08899 2846535 20336145
    • Jopling C, Sleep E, Raya M, Marti M, Raya A, Izpisua Belmonte JC (2010) Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464(7288):606-609. doi: 10.1038/nature08899
    • (2010) Nature , vol.464 , Issue.7288 , pp. 606-609
    • Jopling, C.1    Sleep, E.2    Raya, M.3    Marti, M.4    Raya, A.5    Izpisua Belmonte, J.C.6
  • 11
    • 33845708407 scopus 로고    scopus 로고
    • Re-programming of newt cardiomyocytes is induced by tissue regeneration
    • 10.1242/jcs.03252 17077121
    • Laube F, Heister M, Scholz C, Borchardt T, Braun T (2006) Re-programming of newt cardiomyocytes is induced by tissue regeneration. J Cell Sci 119(Pt 22):4719-4729. doi: 10.1242/jcs.03252
    • (2006) J Cell Sci , vol.119 , Issue.PART 22 , pp. 4719-4729
    • Laube, F.1    Heister, M.2    Scholz, C.3    Borchardt, T.4    Braun, T.5
  • 14
    • 15044351753 scopus 로고    scopus 로고
    • Cardiac remodeling and failure from molecules to man (Part II)
    • 10.1016/j.carpath.2005.01.005
    • Fedak PW, Verma S, Weisel RD, Li RK (2005) Cardiac remodeling and failure from molecules to man (Part II). Cardiovasc pathol: Off J Soc Cardiovasc Pathol 14(2):49-60. doi: 10.1016/j.carpath.2005.01.005
    • (2005) Cardiovasc Pathol: Off J Soc Cardiovasc Pathol , vol.14 , Issue.2 , pp. 49-60
    • Fedak, P.W.1    Verma, S.2    Weisel, R.D.3    Li, R.K.4
  • 15
    • 0037465434 scopus 로고    scopus 로고
    • Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: Structural deterioration and compensatory mechanisms
    • 12600911
    • Hein S, Arnon E, Kostin S, Schonburg M, Elsasser A, Polyakova V, Bauer EP, Klovekorn WP, Schaper J (2003) Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation 107(7):984-991
    • (2003) Circulation , vol.107 , Issue.7 , pp. 984-991
    • Hein, S.1    Arnon, E.2    Kostin, S.3    Schonburg, M.4    Elsasser, A.5    Polyakova, V.6    Bauer, E.P.7    Klovekorn, W.P.8    Schaper, J.9
  • 16
    • 84873806643 scopus 로고    scopus 로고
    • Regenerating new heart with stem cells
    • 10.1172/JCI63068 3533279 23281411
    • Anversa P, Kajstura J, Rota M, Leri A (2013) Regenerating new heart with stem cells. J Clin Investig 123(1):62-70. doi: 10.1172/JCI63068
    • (2013) J Clin Investig , vol.123 , Issue.1 , pp. 62-70
    • Anversa, P.1    Kajstura, J.2    Rota, M.3    Leri, A.4
  • 17
    • 84865586758 scopus 로고    scopus 로고
    • Translational findings from cardiovascular stem cell research
    • 10.1016/j.tcm.2012.05.017 3563254 22940024
    • Mazhari R, Hare JM (2012) Translational findings from cardiovascular stem cell research. Trends Cardiovasc Med 22(1):1-6. doi: 10.1016/j.tcm.2012.05.017
    • (2012) Trends Cardiovasc Med , vol.22 , Issue.1 , pp. 1-6
    • Mazhari, R.1    Hare, J.M.2
  • 20
    • 0344825953 scopus 로고    scopus 로고
    • Athlete's heart
    • 1767992 14617564
    • Fagard R (2003) Athlete's heart. Heart 89(12):1455-1461
    • (2003) Heart , vol.89 , Issue.12 , pp. 1455-1461
    • Fagard, R.1
  • 21
    • 0023770873 scopus 로고
    • Left ventricular mass as determined by magnetic resonance imaging in male endurance athletes
    • 2969673
    • Milliken MC, Stray-Gundersen J, Peshock RM, Katz J, Mitchell JH (1988) Left ventricular mass as determined by magnetic resonance imaging in male endurance athletes. Am J Cardiol 62(4):301-305
    • (1988) Am J Cardiol , vol.62 , Issue.4 , pp. 301-305
    • Milliken, M.C.1    Stray-Gundersen, J.2    Peshock, R.M.3    Katz, J.4    Mitchell, J.H.5
  • 22
    • 79955161098 scopus 로고    scopus 로고
    • The athlete's heart vs the failing heart: Can signaling explain the two distinct outcomes?
    • 10.1152/physiol.00043.2010 21487028
    • Weeks KL, McMullen JR (2011) The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes? Physiology 26(2):97-105. doi: 10.1152/physiol.00043.2010
    • (2011) Physiology , vol.26 , Issue.2 , pp. 97-105
    • Weeks, K.L.1    McMullen, J.R.2
  • 23
    • 84870200989 scopus 로고    scopus 로고
    • Can exercise teach us how to treat heart disease?
    • 10.1161/CIRCULATIONAHA.111.060376 23184282
    • Mann N, Rosenzweig A (2012) Can exercise teach us how to treat heart disease? Circulation 126(22):2625-2635. doi: 10.1161/CIRCULATIONAHA.111.060376
    • (2012) Circulation , vol.126 , Issue.22 , pp. 2625-2635
    • Mann, N.1    Rosenzweig, A.2
  • 24
    • 84864451460 scopus 로고    scopus 로고
    • Regression of pathological cardiac hypertrophy: Signaling pathways and therapeutic targets
    • 10.1016/j.pharmthera.2012.06.006 3458709 22750195
    • Hou J, Kang YJ (2012) Regression of pathological cardiac hypertrophy: signaling pathways and therapeutic targets. Pharmacol Ther 135(3):337-354. doi: 10.1016/j.pharmthera.2012.06.006
    • (2012) Pharmacol Ther , vol.135 , Issue.3 , pp. 337-354
    • Hou, J.1    Kang, Y.J.2
  • 25
    • 0033678504 scopus 로고    scopus 로고
    • The cytoskeleton and related proteins in the human failing heart
    • 10.1023/A:1009813621103 16228910
    • Kostin S, Hein S, Arnon E, Scholz D, Schaper J (2000) The cytoskeleton and related proteins in the human failing heart. Heart Fail Rev 5(3):271-280. doi: 10.1023/A:1009813621103
    • (2000) Heart Fail Rev , vol.5 , Issue.3 , pp. 271-280
    • Kostin, S.1    Hein, S.2    Arnon, E.3    Scholz, D.4    Schaper, J.5
  • 27
    • 0025341362 scopus 로고
    • Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats
    • 2364493
    • Olivetti G, Capasso JM, Sonnenblick EH, Anversa P (1990) Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats. Circ Res 67(1):23-34
    • (1990) Circ Res , vol.67 , Issue.1 , pp. 23-34
    • Olivetti, G.1    Capasso, J.M.2    Sonnenblick, E.H.3    Anversa, P.4
  • 28
    • 14044279226 scopus 로고    scopus 로고
    • High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction
    • 10.1161/01.CIR.0000155616.07901.35 15699250
    • Kuhl U, Pauschinger M, Noutsias M, Seeberg B, Bock T, Lassner D, Poller W, Kandolf R, Schultheiss HP (2005) High prevalence of viral genomes and multiple viral infections in the myocardium of adults with " idiopathic" left ventricular dysfunction. Circulation 111(7):887-893. doi: 10.1161/01.CIR.0000155616.07901.35
    • (2005) Circulation , vol.111 , Issue.7 , pp. 887-893
    • Kuhl, U.1    Pauschinger, M.2    Noutsias, M.3    Seeberg, B.4    Bock, T.5    Lassner, D.6    Poller, W.7    Kandolf, R.8    Schultheiss, H.P.9
  • 29
    • 23844518111 scopus 로고    scopus 로고
    • Genome-environment interactions in the molecular pathogenesis of dilated cardiomyopathy
    • 10.1007/s00109-005-0664-2 15931504
    • Poller W, Kuhl U, Tschoepe C, Pauschinger M, Fechner H, Schultheiss HP (2005) Genome-environment interactions in the molecular pathogenesis of dilated cardiomyopathy. J Mol Med 83(8):579-586. doi: 10.1007/s00109-005-0664-2
    • (2005) J Mol Med , vol.83 , Issue.8 , pp. 579-586
    • Poller, W.1    Kuhl, U.2    Tschoepe, C.3    Pauschinger, M.4    Fechner, H.5    Schultheiss, H.P.6
  • 30
    • 0030665762 scopus 로고    scopus 로고
    • Increased expression of interleukin-1 beta and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in the hypertrophied and failing heart with pressure overload
    • 9351439
    • Shioi T, Matsumori A, Kihara Y, Inoko M, Ono K, Iwanaga Y, Yamada T, Iwasaki A, Matsushima K, Sasayama S (1997) Increased expression of interleukin-1 beta and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in the hypertrophied and failing heart with pressure overload. Circ Res 81(5):664-671
    • (1997) Circ Res , vol.81 , Issue.5 , pp. 664-671
    • Shioi, T.1    Matsumori, A.2    Kihara, Y.3    Inoko, M.4    Ono, K.5    Iwanaga, Y.6    Yamada, T.7    Iwasaki, A.8    Matsushima, K.9    Sasayama, S.10
  • 31
    • 0034086692 scopus 로고    scopus 로고
    • Pancreatic expression of interferon-gamma protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis
    • 10.1038/76277 10835688
    • Horwitz MS, La Cava A, Fine C, Rodriguez E, Ilic A, Sarvetnick N (2000) Pancreatic expression of interferon-gamma protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis. Nat Med 6(6):693-697. doi: 10.1038/76277
    • (2000) Nat Med , vol.6 , Issue.6 , pp. 693-697
    • Horwitz, M.S.1    La Cava, A.2    Fine, C.3    Rodriguez, E.4    Ilic, A.5    Sarvetnick, N.6
  • 32
    • 0029797142 scopus 로고    scopus 로고
    • Persistent expression of cytokine in the chronic stage of viral myocarditis in mice
    • 8941123
    • Shioi T, Matsumori A, Sasayama S (1996) Persistent expression of cytokine in the chronic stage of viral myocarditis in mice. Circulation 94(11):2930-2937
    • (1996) Circulation , vol.94 , Issue.11 , pp. 2930-2937
    • Shioi, T.1    Matsumori, A.2    Sasayama, S.3
  • 33
    • 0029051198 scopus 로고
    • Expression of leukocyte chemotactic cytokines in myocardial tissue
    • 10.1006/cyto.1995.0037 7640350
    • Seino Y, Ikeda U, Sekiguchi H, Morita M, Konishi K, Kasahara T, Shimada K (1995) Expression of leukocyte chemotactic cytokines in myocardial tissue. Cytokine 7(3):301-304. doi: 10.1006/cyto.1995.0037
    • (1995) Cytokine , vol.7 , Issue.3 , pp. 301-304
    • Seino, Y.1    Ikeda, U.2    Sekiguchi, H.3    Morita, M.4    Konishi, K.5    Kasahara, T.6    Shimada, K.7
  • 34
    • 76749168479 scopus 로고    scopus 로고
    • Monocytes in heart failure: Relationship to a deteriorating immune overreaction or a desperate attempt for tissue repair?
    • 10.1093/cvr/cvp327 19805399
    • Apostolakis S, Lip GY, Shantsila E (2010) Monocytes in heart failure: relationship to a deteriorating immune overreaction or a desperate attempt for tissue repair? Cardiovasc Res 85(4):649-660. doi: 10.1093/cvr/cvp327
    • (2010) Cardiovasc Res , vol.85 , Issue.4 , pp. 649-660
    • Apostolakis, S.1    Lip, G.Y.2    Shantsila, E.3
  • 35
    • 34247849521 scopus 로고    scopus 로고
    • Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice
    • 10.2353/ajpath.2007.060547 1864893 17322368
    • van Amerongen MJ, Harmsen MC, van Rooijen N, Petersen AH, van Luyn MJ (2007) Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J pathol 170(3):818-829. doi: 10.2353/ajpath.2007.060547
    • (2007) Am J Pathol , vol.170 , Issue.3 , pp. 818-829
    • Van Amerongen, M.J.1    Harmsen, M.C.2    Van Rooijen, N.3    Petersen, A.H.4    Van Luyn, M.J.5
  • 38
    • 84857219301 scopus 로고    scopus 로고
    • The Janus face of OSM-mediated cardiomyocyte dedifferentiation during cardiac repair and disease
    • 10.4161/cc.11.3.19024 22262173
    • Poling J, Gajawada P, Lorchner H, Polyakova V, Szibor M, Bottger T, Warnecke H, Kubin T, Braun T (2012) The Janus face of OSM-mediated cardiomyocyte dedifferentiation during cardiac repair and disease. Cell Cycle 11(3):439-445. doi: 10.4161/cc.11.3.19024
    • (2012) Cell Cycle , vol.11 , Issue.3 , pp. 439-445
    • Poling, J.1    Gajawada, P.2    Lorchner, H.3    Polyakova, V.4    Szibor, M.5    Bottger, T.6    Warnecke, H.7    Kubin, T.8    Braun, T.9
  • 40
    • 2642558605 scopus 로고    scopus 로고
    • Oncostatin-M in myocardial ischemia/reperfusion injury may regulate tissue repair
    • 15103750
    • Gwechenberger M, Moertl D, Pacher R, Huelsmann M (2004) Oncostatin-M in myocardial ischemia/reperfusion injury may regulate tissue repair. Croat Med J 45(2):149-157
    • (2004) Croat Med J , vol.45 , Issue.2 , pp. 149-157
    • Gwechenberger, M.1    Moertl, D.2    Pacher, R.3    Huelsmann, M.4
  • 41
    • 0025924392 scopus 로고
    • Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation
    • 1999010
    • Ross J Jr (1991) Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation. Circulation 83(3):1076-1083
    • (1991) Circulation , vol.83 , Issue.3 , pp. 1076-1083
    • Ross, Jr.J.1
  • 42
    • 0028324080 scopus 로고
    • Insulin-like growth factor i stimulates myofibril development and decreases smooth muscle alpha-actin of adult cardiomyocytes
    • 43228 8127866
    • Donath MY, Zapf J, Eppenberger-Eberhardt M, Froesch ER, Eppenberger HM (1994) Insulin-like growth factor I stimulates myofibril development and decreases smooth muscle alpha-actin of adult cardiomyocytes. Proc Natl Acad Sci USA 91(5):1686-1690
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.5 , pp. 1686-1690
    • Donath, M.Y.1    Zapf, J.2    Eppenberger-Eberhardt, M.3    Froesch, E.R.4    Eppenberger, H.M.5
  • 43
    • 0028831539 scopus 로고
    • Chronic ischemic viable myocardium in man: Aspects of dedifferentiation. Cardiovasc Pathol
    • Ausma J, Schaart G, Thoné F, Shivalkar B, Flameng W, Depre C, Vanoverschelde J-L, Ramaekers F, Borgers M (1995) Chronic ischemic viable myocardium in man: aspects of dedifferentiation. Cardiovasc Pathol: Off J Soc Cardiovasc Pathol 4(1):29-37. http://dx.doi.org/10.1016/1054-8807(94)00028-P
    • (1995) J Soc Cardiovasc Pathol , vol.4 , Issue.1 , pp. 29-37
    • Ausma J, S.1
  • 44
    • 0036290206 scopus 로고    scopus 로고
    • Dissociation of cardiomyocyte apoptosis and dedifferentiation in infarct border zones
    • 10.1053/euhj.2001.2963 12042006
    • Dispersyn GD, Mesotten L, Meuris B, Maes A, Mortelmans L, Flameng W, Ramaekers F, Borgers M (2002) Dissociation of cardiomyocyte apoptosis and dedifferentiation in infarct border zones. Eur Heart J 23(11):849-857. doi: 10.1053/euhj.2001.2963
    • (2002) Eur Heart J , vol.23 , Issue.11 , pp. 849-857
    • Dispersyn, G.D.1    Mesotten, L.2    Meuris, B.3    Maes, A.4    Mortelmans, L.5    Flameng, W.6    Ramaekers, F.7    Borgers, M.8
  • 45
    • 0024191263 scopus 로고
    • Sequential activation of alpha-actin genes during avian cardiogenesis: Vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation
    • 3204121
    • Ruzicka DL, Schwartz RJ (1988) Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation. J cell biol 107(6 Pt 2):2575-2586
    • (1988) J Cell Biol , vol.107 , Issue.6 PART 2 , pp. 2575-2586
    • Ruzicka, D.L.1    Schwartz, R.J.2
  • 46
    • 70349213385 scopus 로고    scopus 로고
    • Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster
    • 10.1172/JCI38864 2735940 19690389
    • Boettger T, Beetz N, Kostin S, Schneider J, Kruger M, Hein L, Braun T (2009) Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Investig 119(9):2634-2647. doi: 10.1172/JCI38864
    • (2009) J Clin Investig , vol.119 , Issue.9 , pp. 2634-2647
    • Boettger, T.1    Beetz, N.2    Kostin, S.3    Schneider, J.4    Kruger, M.5    Hein, L.6    Braun, T.7
  • 47
    • 0031717006 scopus 로고    scopus 로고
    • Differential protein localization in sarcomeric and nonsarcomeric contractile structures of cultured cardiomyocytes
    • 10.1006/jsbi.1998.3981 9724617
    • Harder BA, Hefti MA, Eppenberger HM, Schaub MC (1998) Differential protein localization in sarcomeric and nonsarcomeric contractile structures of cultured cardiomyocytes. J Struct Biol 122(1-2):162-175. doi: 10.1006/jsbi.1998.3981
    • (1998) J Struct Biol , vol.122 , Issue.1-2 , pp. 162-175
    • Harder, B.A.1    Hefti, M.A.2    Eppenberger, H.M.3    Schaub, M.C.4
  • 50
    • 0029967959 scopus 로고    scopus 로고
    • Triiodothyronine induces over-expression of alpha-smooth muscle actin, restricts myofibrillar expansion and is permissive for the action of basic fibroblast growth factor and insulin-like growth factor i in adult rat cardiomyocytes
    • 10.1172/JCI118972 507611 8878423
    • Gosteli-Peter MA, Harder BA, Eppenberger HM, Zapf J, Schaub MC (1996) Triiodothyronine induces over-expression of alpha-smooth muscle actin, restricts myofibrillar expansion and is permissive for the action of basic fibroblast growth factor and insulin-like growth factor I in adult rat cardiomyocytes. J Clin Investig 98(8):1737-1744. doi: 10.1172/JCI118972
    • (1996) J Clin Investig , vol.98 , Issue.8 , pp. 1737-1744
    • Gosteli-Peter, M.A.1    Harder, B.A.2    Eppenberger, H.M.3    Zapf, J.4    Schaub, M.C.5
  • 51
    • 0033677831 scopus 로고    scopus 로고
    • Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture
    • 11034912
    • Person V, Kostin S, Suzuki K, Labeit S, Schaper J (2000) Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture. J Cell Sci 113(Pt 21):3851-3859
    • (2000) J Cell Sci , vol.113 , Issue.PART 21 , pp. 3851-3859
    • Person, V.1    Kostin, S.2    Suzuki, K.3    Labeit, S.4    Schaper, J.5
  • 53
    • 0024369465 scopus 로고
    • Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate
    • 2481569
    • Kubin T, Yanagida M, Mori S, Hayashi Y, Gohda E, Yamamoto I (1989) Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate. Cell Biol Int Rep 13(11):907-917
    • (1989) Cell Biol Int Rep , vol.13 , Issue.11 , pp. 907-917
    • Kubin, T.1    Yanagida, M.2    Mori, S.3    Hayashi, Y.4    Gohda, E.5    Yamamoto, I.6
  • 54
    • 34548695952 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in heart development and diseases
    • 10.1161/CIRCULATIONAHA.106.679589 17875982
    • Wang Y (2007) Mitogen-activated protein kinases in heart development and diseases. Circulation 116(12):1413-1423. doi: 10.1161/CIRCULATIONAHA.106.679589
    • (2007) Circulation , vol.116 , Issue.12 , pp. 1413-1423
    • Wang, Y.1
  • 56
    • 59449110495 scopus 로고    scopus 로고
    • Metabolic remodelling of the failing heart: Beneficial or detrimental?
    • 10.1093/cvr/cvn282 18854380
    • van Bilsen M, van Nieuwenhoven FA, van der Vusse GJ (2009) Metabolic remodelling of the failing heart: beneficial or detrimental? Cardiovasc Res 81(3):420-428. doi: 10.1093/cvr/cvn282
    • (2009) Cardiovasc Res , vol.81 , Issue.3 , pp. 420-428
    • Van Bilsen, M.1    Van Nieuwenhoven, F.A.2    Van Der Vusse, G.J.3
  • 57
    • 0025032710 scopus 로고
    • Future perspectives in basic science understanding of congestive heart failure
    • 2201184
    • Katz AM (1990) Future perspectives in basic science understanding of congestive heart failure. Am J Cardiol 66(4):468-471
    • (1990) Am J Cardiol , vol.66 , Issue.4 , pp. 468-471
    • Katz, A.M.1
  • 58
    • 0029049337 scopus 로고
    • Myocardial Ca(2 +)- and ATP-cycling imbalances in end-stage dilated and ischemic cardiomyopathies
    • 7585831
    • O'Brien PJ, Gwathmey JK (1995) Myocardial Ca(2 +)- and ATP-cycling imbalances in end-stage dilated and ischemic cardiomyopathies. Cardiovasc Res 30(3):394-404
    • (1995) Cardiovasc Res , vol.30 , Issue.3 , pp. 394-404
    • O'Brien, P.J.1    Gwathmey, J.K.2
  • 62
    • 77951152823 scopus 로고    scopus 로고
    • Myoglobin-deficient mice activate a distinct cardiac gene expression program in response to isoproterenol-induced hypertrophy
    • 10.1152/physiolgenomics.90297.2008 20145201
    • Molojavyi A, Lindecke A, Raupach A, Moellendorf S, Kohrer K, Godecke A (2010) Myoglobin-deficient mice activate a distinct cardiac gene expression program in response to isoproterenol-induced hypertrophy. Physiol Genomics 41(2):137-145. doi: 10.1152/physiolgenomics.90297.2008
    • (2010) Physiol Genomics , vol.41 , Issue.2 , pp. 137-145
    • Molojavyi, A.1    Lindecke, A.2    Raupach, A.3    Moellendorf, S.4    Kohrer, K.5    Godecke, A.6
  • 63
    • 84856739946 scopus 로고    scopus 로고
    • Hypoxia-inducible factors in physiology and medicine
    • 10.1016/j.cell.2012.01.021 3437543 22304911
    • Semenza GL (2012) Hypoxia-inducible factors in physiology and medicine. Cell 148(3):399-408. doi: 10.1016/j.cell.2012.01.021
    • (2012) Cell , vol.148 , Issue.3 , pp. 399-408
    • Semenza, G.L.1
  • 64
    • 79957960940 scopus 로고    scopus 로고
    • Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
    • 10.1016/j.bbamcr.2010.09.019 3035754 20933024
    • Scarpulla RC (2011) Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim Biophys Acta 1813(7):1269-1278. doi: 10.1016/j.bbamcr.2010.09.019
    • (2011) Biochim Biophys Acta , vol.1813 , Issue.7 , pp. 1269-1278
    • Scarpulla, R.C.1
  • 65
    • 0036118875 scopus 로고    scopus 로고
    • Mitochondrial proteins in hypertrophy and atrophy: A transcript analysis in rat heart
    • 11985548
    • Taegtmeyer H, Razeghi P, Young ME (2002) Mitochondrial proteins in hypertrophy and atrophy: a transcript analysis in rat heart. Clin Exp Pharmacol Physiol 29(4):346-350
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , Issue.4 , pp. 346-350
    • Taegtmeyer, H.1    Razeghi, P.2    Young, M.E.3
  • 66
    • 80255129364 scopus 로고    scopus 로고
    • Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart
    • 10.1016/j.biocel.2011.08.008 21871578
    • Lemieux H, Semsroth S, Antretter H, Hofer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43(12):1729-1738. doi: 10.1016/j.biocel.2011.08.008
    • (2011) Int J Biochem Cell Biol , vol.43 , Issue.12 , pp. 1729-1738
    • Lemieux, H.1    Semsroth, S.2    Antretter, H.3    Hofer, D.4    Gnaiger, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.