Adaptive mechanisms that preserve cardiac function in mice without myoglobin

Circulation Research

Volumn 88, Issue 7, 2001, Pages 713-720

  Meeson, A P ^a   Radford, N ^a   Shelton, J M ^a   Mammen, P P A ^a   DiMaio, J M ^a   Hutcheson, K ^a   Kong, Y ^a   Elterman, J ^a   Williams, R S ^a   Garry, D J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Hypoxia; Metabolism; Myoglobin; Transgenic mice; Vasculature

Indexed keywords

HEAT SHOCK PROTEIN 27; MYOGLOBIN; TRANSCRIPTION FACTOR; VASCULOTROPIN;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; FETUS DEATH; GENE INDUCTION; GESTATIONAL AGE; HEART FUNCTION; HEART MUSCLE OXYGEN CONSUMPTION; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; STRESS; SURVIVAL; VASCULARIZATION;

EID: 0035853389     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh0701.089753     Document Type: Article

References (30)

1. Transport of oxygen in muscle
2. Postnatal development and plasticity of specialized muscle fiber characteristics in the hindlimb
3. Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart
4. The metabolic implications of intracellular circulation
5. 2 in myocardium as determined by 1H nuclear magnetic resonance signal of myoglobin
6. Myoglobin function and energy metabolism of isolated cardiac myocytes: Effect of sodium nitrite
7. Myoglobin content and oxygen diffusion: Model analysis of horse and steer muscle
8. Mice without myoglobin
9. Persistent expression of MNF identifies myogenic stem cells in postnatal muscles
10. Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo
11. A work-performing heart preparation for myocardial performance analysis in murine hearts
12. Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations
13. Analysis of tricarboxylic acid cycle of the heart using 13C isotope isomers
14. Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy
15. Assessment of cardiomyocyte DNA synthesis during hypertrophy in adult mice
16. Tumor suppressor gene expression during normal and pathologic myocardial growth
17. Disruption of myoglobin in mice induces multiple compensatory mechanisms
18. Motoneuron and muscle fiber succinate dehydrogenase activity in control and overloaded plantaris
19. In vivo assessment of embryonic cardiovascular dimensions and function in day-10.5 to 14.5 mouse embryos
20. Oxygen uptake during early cardiogenesis of the chick
21. Species differences in cardiac energetics
22. Oxygen, genes, and development: An analysis of the role of hypoxic gene regulation during murine vascular development
23. Cardiovascular lesions and skeletal myopathy in mice lacking desmin
24. Muscle creatine kinase-deficient mice
25. Impaired cardiac energetics in mice lacking muscle-specific isoenzymes of creatine kinase
26. Perspectives on oxygen sensing
27. Hypoxia response elements in the aldolase A, enolase 1 and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
28. HIF-1α is required for solid tumor formation and embryonic vascularization
29. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
30. Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α