Cardiac remodeling and failure: From molecules to man (Part II)

Cardiovascular Pathology

Volumn 14, Issue 2, 2005, Pages 49-60

  Fedak, Paul W M ^a   Verma, Subodh ^a   Weisel, Richard D ^a   Li, Ren Ke ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cardiac remodeling; Congestive heart failure; Extracellular matrix; Matrix metalloproteinases; Tissue inhibitor of matrix metalloproteinases

Indexed keywords

COLLAGEN; DISINTEGRIN; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

DISEASE COURSE; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME REGULATION; EXTRACELLULAR MATRIX; HEART DISEASE; HEART FAILURE; HEART FUNCTION; HEART MUSCLE; HEART SIZE; HEART VENTRICLE REMODELING; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; TISSUE INJURY; TRANSGENIC MOUSE;

EID: 15044351753     PISSN: 10548807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carpath.2005.01.005     Document Type: Article

References (115)

1. P Libby, and RT Lee Matrix matters Circulation 102 16 2000 1874 1876
2. KT Weber Cardiac interstitium in health and disease: the fibrillar collagen network J Am Coll Cardiol 13 7 1989 1637 1652
3. BR Olsen New insights into the function of collagens from genetic analysis Curr Opin Cell Biol 7 5 1995 720 727
4. BS Burlew, and KT Weber Connective tissue and the heart. Functional significance and regulatory mechanisms Cardiol Clin 18 3 2000 435 442
5. ME Lukashev, and Z Werb ECM signalling: orchestrating cell behaviour and misbehaviour Trends Cell Biol 8 11 1998 437 441
6. RS Ross, and TK Borg Integrins and the myocardium Circ Res 88 11 2001 1112 1119
7. RK Assoian, and EE Marcantonio The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis J Clin Invest 100 11 Suppl 1997 S15 S18
8. CA Buck, HS Baldwin, H DeLisser, C Mickanin, HM Shen, G Kennedy, A Chen, JM Edelman, and SM Albelda Cell adhesion receptors and early mammalian heart development: an overview C R Acad Sci III 316 9 1993 838 859
9. E Ogawa, Y Saito, M Harada, S Kamitani, K Kuwahara, Y Miyamoto, M Ishikawa, I Hamanaka, N Kajiyama, N Takahashi, O Nakagawa, I Masuda, I Kishimoto, and K Nakao Outside-in signalling of fibronectin stimulates cardiomyocyte hypertrophy in cultured neonatal rat ventricular myocytes J Mol Cell Cardiol 32 5 2000 765 776
10. DG Simpson, L Terracio, M Terracio, RL Price, DC Turner, and TK Borg Modulation of cardiac myocyte phenotype in vitro by the composition and orientation of the extracellular matrix J Cell Physiol 161 1 1994 89 105
11. LK Hornberger, S Singhroy, T Cavalle-Garrido, W Tsang, F Keeley, and M Rabinovitch Synthesis of extracellular matrix and adhesion through beta(1) integrins are critical for fetal ventricular myocyte proliferation Circ Res 87 6 2000 508 515
12. RS Ross, C Pham, SY Shai, JI Goldhaber, C Fenczik, CC Glembotski, MH Ginsberg, and JC Loftus Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes Circ Res 82 11 1998 1160 1172
13. B Ding, RL Price, EC Goldsmith, TK Borg, X Yan, PS Douglas, EO Weinberg, J Bartunek, T Thielen, VV Didenko, and BH Lorell Left ventricular hypertrophy in ascending aortic stenosis mice: anoikis and the progression to early failure Circulation 101 24 2000 2854 2862
14. R Zak Cell proliferation during cardiac growth Am J Cardiol 31 2 1973 211 219
15. M Eghbali, MJ Czaja, M Zeydel, FR Weiner, MA Zern, S Seifter, and OO Blumenfeld Collagen chain mRNAs in isolated heart cells from young and adult rats J Mol Cell Cardiol 20 3 1988 267 276
16. JB Caulfield, and TK Borg The collagen network of the heart Lab Invest 40 3 1979 364 372
17. TF Robinson, L Cohen-Gould, and SM Factor Skeletal framework of mammalian heart muscle. Arrangement of inter- and pericellular connective tissue structures Lab Invest 49 4 1983 482 498
18. KT Weber, Y Sun, SC Tyagi, and JP Cleutjens Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms J Mol Cell Cardiol 26 3 1994 279 292
19. M Komeda, TE David, V Rao, Z Sun, RD Weisel, and RJ Burns Late hemodynamic effects of the preserved papillary muscles during mitral valve replacement Circulation 90 5 Pt 2 1994 II190 II194
20. TF Robinson, MA Geraci, EH Sonnenblick, and SM Factor Coiled perimysial fibers of papillary muscle in rat heart: morphology, distribution, and changes in configuration Circ Res 63 3 1988 577 592
21. TF Robinson, SM Factor, JM Capasso, BA Wittenberg, OO Blumenfeld, and S Seifter Morphology, composition, and function of struts between cardiac myocytes of rat and hamster Cell Tissue Res 249 2 1987 247 255
22. SM Factor, and TF Robinson Comparative connective tissue structure-function relationships in biologic pumps Lab Invest 58 2 1988 150 156
23. HM Spotnitz Macro design, structure, and mechanics of the left ventricle J Thorac Cardiovasc Surg 119 5 2000 1053 1077
24. H Ju, and IM Dixon Extracellular matrix and cardiovascular diseases Can J Cardiol 12 12 1996 1259 1267
25. Y Sun, and KT Weber Infarct scar: a dynamic tissue Cardiovasc Res 46 2 2000 250 256
26. KT Weber, JE Jalil, JS Janicki, and R Pick Myocardial collagen remodeling in pressure overload hypertrophy. A case for interstitial heart disease Am J Hypertens 2 12 Pt 1 1989 931 940
27. MA Silver, R Pick, CG Brilla, JE Jalil, JS Janicki, and KT Weber Reactive and reparative fibrillar collagen remodelling in the hypertrophied rat left ventricle: two experimental models of myocardial fibrosis Cardiovasc Res 24 9 1990 741 747
28. B Swynghedauw Molecular mechanisms of myocardial remodeling Physiol Rev 79 1 1999 215 262
29. CA Beltrami, N Finato, M Rocco, GA Feruglio, C Puricelli, E Cigola, F Quaini, EH Sonnenblick, G Olivetti, and P Anversa Structural basis of end-stage failure in ischemic cardiomyopathy in humans Circulation 89 1 1994 151 163
30. MA Rossi Patterns of myocardial fibrosis in idiopathic cardiomyopathies and chronic chagasic cardiopathy Can J Cardiol 7 7 1991 287 294
31. MM Marijianowski, P Teeling, and AE Becker Remodeling after myocardial infarction in humans is not associated with interstitial fibrosis of noninfarcted myocardium J Am Coll Cardiol 30 1 1997 76 82
32. KT Weber, CG Brilla, and JS Janicki Myocardial fibrosis: functional significance and regulatory factors Cardiovasc Res 27 3 1993 341 348
33. FG Spinale, M Tomita, JL Zellner, JC Cook, FA Crawford, and MR Zile Collagen remodeling and changes in LV function during development and recovery from supraventricular tachycardia Am J Physiol 261 2 Pt 2 1991 H308 H318
34. FG Spinale, JL Zellner, WS Johnson, DM Eble, and PD Munyer Cellular and extracellular remodeling with the development and recovery from tachycardia-induced cardiomyopathy: changes in fibrillar collagen, myocyte adhesion capacity and proteoglycans J Mol Cell Cardiol 28 8 1996 1591 1608
35. AJ Woodiwiss, OJ Tsotetsi, S Sprott, EJ Lancaster, T Mela, ES Chung, TE Meyer, and GR Norton Reduction in myocardial collagen cross-linking parallels left ventricular dilatation in rat models of systolic chamber dysfunction Circulation 103 1 2001 155 160
36. Z Gunja-Smith, AR Morales, R Romanelli, and JF Woessner Remodeling of human myocardial collagen in idiopathic dilated cardiomyopathy. Role of metalloproteinases and pyridinoline cross-links Am J Pathol 148 5 1996 1639 1648
37. MM Marijianowski, P Teeling, J Mann, and AE Becker Dilated cardiomyopathy is associated with an increase in the type I/type III collagen ratio: a quantitative assessment J Am Coll Cardiol 25 6 1995 1263 1272
38. ML Burgess, J Buggy, RL Price, FL Abel, L Terracio, AM Samarel, and TK Borg Exercise- and hypertension-induced collagen changes are related to left ventricular function in rat hearts Am J Physiol 270 1 Pt 2 1996 H151 H159
39. GR Norton, J Tsotetsi, B Trifunovic, C Hartford, GP Candy, and AJ Woodiwiss Myocardial stiffness is attributed to alterations in cross-linked collagen rather than total collagen or phenotypes in spontaneously hypertensive rats Circulation 96 6 1997 1991 1998
40. K Reiser, RJ McCormick, and RB Rucker Enzymatic and nonenzymatic cross-linking of collagen and elastin FASEB J 6 7 1992 2439 2449
41. KL Herrmann, AD McCulloch, and JH Omens Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy Am J Physiol Heart Circ Physiol 284 4 2003 H1277 H1284
42. J Harper, E Harper, and JW Covell Collagen characterization in volume-overload- and pressure-overload-induced cardiac hypertrophy in minipigs Am J Physiol 265 2 Pt 2 1993 H434 H438
43. DS Iimoto, JW Covell, and E Harper Increase in cross-linking of type I and type III collagens associated with volume-overload hypertrophy Circ Res 63 2 1988 399 408
44. JM Capasso, TF Robinson, and P Anversa Alterations in collagen cross-linking impair myocardial contractility in the mouse heart Circ Res 65 6 1989 1657 1664
45. S Kato, FG Spinale, R Tanaka, W Johnson, G Cooper, and MR Zile Inhibition of collagen cross-linking: effects on fibrillar collagen and ventricular diastolic function Am J Physiol 269 3 Pt 2 1995 H863 H868
46. MA Rossi, MA Abreu, and LB Santoro Images in cardiovascular medicine. Connective tissue skeleton of the human heart: a demonstration by cell-maceration scanning electron microscope method Circulation 97 9 1998 934 935
47. JS Janicki, and GL Brower The role of myocardial fibrillar collagen in ventricular remodeling and function J Card Fail 8 6 Suppl 2002 S319 S325
48. FG Spinale, ML Coker, CV Thomas, JD Walker, R Mukherjee, and L Hebbar Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function Circ Res 82 4 1998 482 495
49. EC Goldsmith, and TK Borg The dynamic interaction of the extracellular matrix in cardiac remodeling J Card Fail 8 6 Suppl 2002 S314 S318
50. SM Weis, JL Emery, KD Becker, DJ McBride, JH Omens, and AD McCulloch Myocardial mechanics and collagen structure in the osteogenesis imperfecta murine (oim) Circ Res 87 8 2000 663 669
51. DA MacKenna, SM Vaplon, and AD McCulloch Microstructural model of perimysial collagen fibers for resting myocardial mechanics during ventricular filling Am J Physiol 273 3 Pt 2 1997 H1576 H1586
52. KT Weber, R Pick, JS Janicki, G Gadodia, and JB Lakier Inadequate collagen tethers in dilated cardiopathy Am Heart J 116 6 Pt 1 1988 1641 1646
53. N Boudreau, Z Werb, and MJ Bissell Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle Proc Natl Acad Sci U S A 93 8 1996 3509 3513
54. CM Bonnin, MP Sparrow, and RR Taylor Collagen synthesis and content in right ventricular hypertrophy in the dog Am J Physiol 241 5 1981 H708 H713
55. SC Tyagi Proteinases and myocardial extracellular matrix turnover Mol Cell Biochem 168 1-2 1997 1 12
56. SC Tyagi, A Ratajska, and KT Weber Myocardial matrix metalloproteinase(s) : localization and activation Mol Cell Biochem 126 1 1993 49 59
57. H Nagase, and JF Woessner Matrix metalloproteinases J Biol Chem 274 31 1999 21491 21494
58. FG Spinale Matrix metalloproteinases: regulation and dysregulation in the failing heart Circ Res 90 5 2002 520 530
59. ZS Galis, and JJ Khatri Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly Circ Res 90 3 2002 251 262
60. J Schlondorff, and CP Blobel Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding J Cell Sci 112 Pt 21 1999 3603 3617
61. M Asakura, M Kitakaze, S Takashima, Y Liao, F Ishikura, T Yoshinaka, H Ohmoto, K Node, K Yoshino, H Ishiguro, H Asanuma, S Sanada, Y Matsumura, H Takeda, S Beppu, M Tada, M Hori, and S Higashiyama Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy Nat Med 8 1 2002 35 40
62. M Satoh, M Nakamura, H Saitoh, H Satoh, C Maesawa, I Segawa, A Tashiro, and K Hiramori Tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human dilated cardiomyopathy Circulation 99 25 1999 3260 3265
63. GL Brower, AL Chancey, S Thanigaraj, BB Matsubara, and JS Janicki Cause and effect relationship between myocardial mast cell number and matrix metalloproteinase activity Am J Physiol Heart Circ Physiol 283 2 2002 H518 H525
64. AL Chancey, GL Brower, and JS Janicki Cardiac mast cell-mediated activation of gelatinase and alteration of ventricular diastolic function Am J Physiol Heart Circ Physiol 282 6 2002 H2152 H2158
65. GL Brower, and JS Janicki Contribution of ventricular remodeling to pathogenesis of heart failure in rats Am J Physiol Heart Circ Physiol 280 2 2001 H674 H683
66. ML Coker, CV Thomas, MJ Clair, JW Hendrick, RS Krombach, ZS Galis, and FG Spinale Myocardial matrix metalloproteinase activity and abundance with congestive heart failure Am J Physiol 274 5 Pt 2 1998 H1516 H1523
67. IM Dixon, H Ju, NL Reid, T Scammell-La Fleur, JP Werner, and G Jasmin Cardiac collagen remodeling in the cardiomyopathic Syrian hamster and the effect of losartan J Mol Cell Cardiol 29 7 1997 1837 1850
68. AM Feldman, YY Li, and CF McTiernan Matrix metalloproteinases in pathophysiology and treatment of heart failure Lancet 357 9257 2001 654 655
69. RT Lee, and P Libby Matrix metalloproteinases: not-so-innocent bystanders in heart failure J Clin Invest 106 7 2000 827 828
70. YY Li, CF McTiernan, and AM Feldman Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling Cardiovasc Res 46 2 2000 214 224
71. YY Li, and AM Feldman Matrix metalloproteinases in the progression of heart failure: potential therapeutic implications Drugs 61 9 2001 1239 1252
72. DL Mann, and FG Spinale Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds Circulation 98 17 1998 1699 1702
73. Y Nagatomo, BA Carabello, ML Coker, PJ McDermott, S Nemoto, M Hamawaki, and FG Spinale Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control Am J Physiol Heart Circ Physiol 278 1 2000 H151 H161
74. AM Romanic, CL Burns-Kurtis, B Gout, I Berrebi-Bertrand, and EH Ohlstein Matrix metalloproteinase expression in cardiac myocytes following myocardial infarction in the rabbit Life Sci 68 7 2001 799 814
75. FG Spinale, ML Coker, BR Bond, and JL Zellner Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target Cardiovasc Res 46 2 2000 225 238
76. FG Spinale, ML Coker, LJ Heung, BR Bond, HR Gunasinghe, T Etoh, AT Goldberg, JL Zellner, and AJ Crumbley A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure Circulation 102 16 2000 1944 1949
77. CV Thomas, ML Coker, JL Zellner, JR Handy, AJ Crumbley, and FG Spinale Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy Circulation 97 17 1998 1708 1715
78. O Yokoseki, Y Yazaki, J Suzuki, H Imamura, H Takenaka, and M Isobe Association of matrix metalloproteinase expression and left ventricular function in idiopathic dilated cardiomyopathy Jpn Circ J 64 5 2000 352 357
79. K Masutomo, N Makino, M Sugano, S Miyamoto, T Hata, and T Yanaga Extracellular matrix regulation in the development of Syrian cardiomyopathic Bio 14.6 and Bio 53.58 hamsters J Mol Cell Cardiol 31 9 1999 1607 1615
80. MM Thompson, and IB Squire Matrix metalloproteinase-9 expression after myocardial infarction: physiological or pathological? Cardiovasc Res 54 3 2002 495 498
81. HE Kim, SS Dalal, E Young, MJ Legato, ML Weisfeldt, and J D'Armiento Disruption of the myocardial extracellular matrix leads to cardiac dysfunction J Clin Invest 106 7 2000 857 866
82. A Ducharme, S Frantz, M Aikawa, E Rabkin, M Lindsey, LE Rohde, FJ Schoen, RA Kelly, Z Werb, P Libby, and RT Lee Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction J Clin Invest 106 1 2000 55 62
83. AM Romanic, SM Harrison, W Bao, CL Burns-Kurtis, S Pickering, J Gu, E Grau, J Mao, GM Sathe, EH Ohlstein, and TL Yue Myocardial protection from ischemia/reperfusion injury by targeted deletion of matrix metalloproteinase-9 Cardiovasc Res 54 3 2002 549 558
84. S Heymans, A Luttun, D Nuyens, G Theilmeier, E Creemers, L Moons, GD Dyspersin, JP Cleutjens, M Shipley, A Angellilo, M Levi, O Nube, A Baker, E Keshet, F Lupu, JM Herbert, JF Smits, SD Shapiro, M Baes, M Borgers, D Collen, MJ Daemen, and P Carmeliet Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure Nat Med 5 10 1999 1135 1142
85. LE Rohde, A Ducharme, LH Arroyo, M Aikawa, GH Sukhova, A Lopez-Anaya, KF McClure, PG Mitchell, P Libby, and RT Lee Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice Circulation 99 23 1999 3063 3070
86. FG Spinale, ML Coker, SR Krombach, R Mukherjee, H Hallak, WV Houck, MJ Clair, SB Kribbs, LL Johnson, JT Peterson, and MR Zile Matrix metalloproteinase inhibition during the development of congestive heart failure: effects on left ventricular dimensions and function Circ Res 85 4 1999 364 376
87. ML Lindsey, J Gannon, M Aikawa, FJ Schoen, E Rabkin, L Lopresti-Morrow, J Crawford, S Black, P Libby, PG Mitchell, and RT Lee Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction Circulation 105 6 2002 753 758
88. WM Yarbrough, R Mukherjee, TA Brinsa, KB Dowdy, AA Scott, GP Escobar, C Joffs, DG Lucas, FA Crawford, and FG Spinale Matrix metalloproteinase inhibition modifies left ventricular remodeling after myocardial infarction in pigs J Thorac Cardiovasc Surg 125 3 2003 602 610
89. MK King, ML Coker, A Goldberg, JH McElmurray, HR Gunasinghe, R Mukherjee, MR Zile, TP O'Neill, and FG Spinale Selective matrix metalloproteinase inhibition with developing heart failure: effects on left ventricular function and structure Circ Res 92 2 2003 177 185
90. R Mukherjee, TA Brinsa, KB Dowdy, AA Scott, JM Baskin, AM Deschamps, AS Lowry, GP Escobar, DG Lucas, WM Yarbrough, MR Zile, and FG Spinale Myocardial infarct expansion and matrix metalloproteinase inhibition Circulation 107 4 2003 618 625
91. CF Baicu, JD Stroud, VA Livesay, E Hapke, J Holder, FG Spinale, and MR Zile Changes in extracellular collagen matrix alter myocardial systolic performance Am J Physiol Heart Circ Physiol 284 1 2003 H122 H132
92. W Wang, CJ Schulze, WL Suarez-Pinzon, JR Dyck, G Sawicki, and R Schulz Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury Circulation 106 12 2002 1543 1549
93. EE Creemers, JP Cleutjens, JF Smits, and MJ Daemen Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure? Circ Res 89 3 2001 201 210
94. YY Li, CF McTiernan, and AM Feldman Proinflammatory cytokines regulate tissue inhibitors of metalloproteinases and disintegrin metalloproteinase in cardiac cells Cardiovasc Res 42 1 1999 162 172
95. YY Li, YQ Feng, T Kadokami, CF McTiernan, R Draviam, SC Watkins, and AM Feldman Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy Proc Natl Acad Sci U S A 97 23 2000 12746 12751
96. K Brew, D Dinakarpandian, and H Nagase Tissue inhibitors of metalloproteinases: evolution, structure and function Biochim Biophys Acta 1477 1-2 2000 267 283
97. AH Baker, DR Edwards, and G Murphy Metalloproteinase inhibitors: biological actions and therapeutic opportunities Cell Sci 115 Pt 19 2002 3719 3727
98. Y Jiang, ID Goldberg, and YE Shi Complex roles of tissue inhibitors of metalloproteinases in cancer Oncogene 21 14 2002 2245 2252
99. T Hayakawa Multiple functions of tissue inhibitors of metalloproteinases (TIMPs): a new aspect involving osteoclastic bone resorption J Bone Miner Metab 20 1 2002 1 13
100. F Mannello, and G Gazzanelli Tissue inhibitors of metalloproteinases and programmed cell death: conundrums, controversies and potential implications Apoptosis 6 6 2001 479 482
101. G Fassina, N Ferrari, C Brigati, R Benelli, L Santi, DM Noonan, and A Albini Tissue inhibitors of metalloproteases: regulation and biological activities Clin Exp Metastasis 18 2 2000 111 120
102. PR Brauer, and DH Cai Expression of tissue inhibitor of metalloproteinases (TIMPs) during early cardiac development Mech Dev 113 2 2002 175 179
103. J Greene, M Wang, YE Liu, LA Raymond, C Rosen, and YE Shi Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4 J Biol Chem 271 48 1996 30375 30380
104. K Baghelai, R Marktanner, JB Dattilo, MP Dattilo, ER Jakoi, DR Yager, RG Makhoul, and AS Wechsler Decreased expression of tissue inhibitor of metalloproteinase 1 in stunned myocardium J Surg Res 77 1 1998 35 39
105. SC Tyagi, S Kumar, DJ Voelker, HK Reddy, JS Janicki, and JJ Curtis Differential gene expression of extracellular matrix components in dilated cardiomyopathy J Cell Biochem 63 2 1996 185 198
106. VS Mujumdar, and SC Tyagi Temporal regulation of extracellular matrix components in transition from compensatory hypertrophy to decompensatory heart failure J Hypertens 17 2 1999 261 270
107. YY Li, AM Feldman, Y Sun, and CF McTiernan Differential expression of tissue inhibitors of metalloproteinases in the failing human heart Circulation 98 17 1998 1728 1734
108. L Roten, S Nemoto, J Simsic, ML Coker, V Rao, S Baicu, G Defreyte, PJ Soloway, MR Zile, and FG Spinale Effects of gene deletion of the tissue inhibitor of the matrix metalloproteinase-type 1 (TIMP-1) on left ventricular geometry and function in mice J Mol Cell Cardiol 32 1 2000 109 120
109. EE Creemers, JN Davis, AM Parkhurst, P Leenders, KB Dowdy, E Hapke, AM Hauet, PG Escobar, JP Cleutjens, JF Smits, MJ Daemen, MR Zile, and FG Spinale Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice Am J Physiol Heart Circ Physiol 284 1 2003 H364 H371
110. R Visse, and H Nagase Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry Circ Res 92 8 2003 827
111. JF Woessner That impish TIMP: the tissue inhibitor of metalloproteinases-3 J Clin Invest 108 6 2001 799 800
112. A Amour, PM Slocombe, A Webster, M Butler, CG Knight, BJ Smith, PE Stephens, C Shelley, M Hutton, V Knauper, AJ Docherty, and G Murphy TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3 FEBS Lett 435 1 1998 39 44
113. MD Sternlicht, and Z Werb How matrix metalloproteinases regulate cell behavior Annu Rev Cell Dev Biol 17 2001 463 516
114. PW Fedak, SM Altamentova, RD Weisel, N Nili, N Ohno, S Verma, TY Lee, C Kiani, DA Mickle, BH Strauss, and RK Li Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3 Am J Physiol Heart Circ Physiol 284 2 2003 H626 H634
115. PW Fedak, DS Smookler, Z Kassiri, N Ohno, KJ Leco, S Verma, DA Mickle, KL Watson, CV Hojilla, W Cruz, RD Weisel, RK Li, and R Khokha TIMP-3 deficiency leads to dilated cardiomyopathy Circulation 110 16 2004 2401 2409