Porcine aortic endothelial cells show little effects on smooth muscle cells but are potent stimulators of cardiomyocyte growth

Molecular and Cellular Biochemistry

Volumn 242, Issue 1-2, 2003, Pages 39-45

  Kubin, Thomas ^a   Vogel, Sabina ^b   Wetzel, Jutta ^a   Hein, Stefan ^a   Pipp, Frederic ^b   Herold, Jörg ^b   Heil, Matthias ^b   Kampmann, Andreas ^a   Hehlgans, Stephanie ^a   von der Ahe, Dietmar ^a   Schaper, Wolfgang ^b   Zimmermann, René ^a  

^a KERCKHOFF HEART CENTER   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Cardiomyocytes; Endothelial cells; Growth; Proliferation; Remodeling; Smooth muscle cells

Indexed keywords

ALPHA ACTIN; ALPHA ACTININ; CD31 ANTIGEN; DESMIN; DNA; PLATELET DERIVED GROWTH FACTOR AB; TRITIUM; TROPOMYOSIN;

ANGIOGENESIS; ANIMAL CELL; AORTA; ARTICLE; ATHEROSCLEROSIS; BLOOD; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DNA SYNTHESIS; ENDOTHELIUM CELL; FETAL CALF SERUM; FLUORESCENCE ACTIVATED CELL SORTING; FORCE; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; MORPHOGENESIS; NEWBORN; NONHUMAN; PHENOTYPE; PROTEIN SYNTHESIS; SMOOTH MUSCLE FIBER; SUPERNATANT; SWINE;

ANIMALS; ANIMALS, NEWBORN; AORTA; CELL DIVISION; CELLS, CULTURED; DNA; ENDOTHELIUM, VASCULAR; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, CARDIAC; MYOCYTES, SMOOTH MUSCLE; PROTEIN BIOSYNTHESIS; RATS; RATS, WISTAR; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0037281379     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021177326151     Document Type: Article

References (13)

1. Schaper W, Piek JJ, Munoz-Chapuli R, Wolf C, Ito W: Collateral circulation of the heart. In: J.A. Ware, M. Simons (eds). Angiogenesis and Cardiovascular Disease. Oxford University Press, New York, Oxford, 1999, pp 159-198
2. Kubin T, Ando, H, Scholz D, Bramlage P, Kostin S, van Veen A, Hein S, Fischer S, Breier A, Schaper J, Schaper W: Microvascular endothelial cells remodel cultured adult cardiomyocytes and increase survival. Am J Physiol 45: H2179-H2187, 1999
3. Ando H, Kubin T, Schaper W, Schaper J: Porcine coronary microvascular endothelial cells express α-smooth muscle actin and show low NOS III activity. Am J Physiol 45: H1755-H1768, 1999
4. Smirnov VN, Orekhov AN: Smooth muscle cells from adult human aorta. In: H.M. Piper (ed). Cell Culture Techniques in Heart and Vessel Research. Springer, Berlin, 1990, pp 271-289
5. Shah AM: Paracrine modulation of heart cell function by endothelial cells. Cardiovasc Res 31: 847-867, 1996
6. Elsässer A, Schlepper M, Klövekorn WP, Cai WJ, Zimmermann R, Müller KD, Strasser R, Kostin S, Gagel C, Münkel B, Schaper W, Schaper J: Hibernating myocardium. Circulation 96: 2920-2931, 1997
7. Schwartz SM, deBlois D, O'Brien ERM: The intima-soil for atherosclerosis and restenosis. Circ Res 77: 445-465, 1995
8. Owens GK: Regulation of differentiation of vascular smooth muscle cells. Physiol Rev 75: 487-517, 1995
9. Kassab GS, Rider CA, Tang NJ, Fung YCB: Morphometry of pig coronary arterial trees. Am J Physiol 265: H350-H365, 1993
10. Kassab GS, Fung YCB: Topology and dimensions of pig coronary capillary network. Am J Physiol 267: H319-H325, 1994
11. Shay JW, Wright WE: Hayflick, his limit, and cellular aging. Nature Rev 1: 72-76, 2000
12. Hughes AD, Clunn GF, Refson J, Demoliou-Mason C: Platelet-derived growth factor (PDGF): Actions and mechanisms in vascular smooth muscle. Gen Pharmac 27: 1079-1089, 1996
13. Bowen-Pope DF, Hart CE, Seifert RA: Sera and conditioned media contain different isoforms of platelet-derived growth factor (PDGF) which bind to different classes of PDGF receptor. J Biol Chem 264: 2502-2508, 1989