Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertension

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 6, 2014, Pages

  Zhang, Ruifeng ^a   Shi, Liuhong ^a   Zhou, Lin ^b   Zhang, Gensheng ^c   Wu, Xiaohong ^a   Shao, Fangchun ^a   Ma, Guofeng ^a   Ying, Kejing ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

HIF 2 ; Hypoxic pulmonary hypertension; Remodeling; Transgelin

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LENTIVIRUS VECTOR; MESSENGER RNA; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; TRANSGELIN; ACTIN BINDING PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; MUSCLE PROTEIN; SMAD3 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; HEART RIGHT VENTRICLE PRESSURE; HUMAN; HUMAN CELL; HYPOXIA; HYPOXIC PULMONARY HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; LUCIFERASE ASSAY; LUNG BLOOD VESSEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RAT; REGULATORY MECHANISM; RNA INTERFERENCE; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; CELL CULTURE; CELL HYPOXIA; GENETICS; HIF-2Α; METABOLISM; PROMOTER REGION; PROTEIN BINDING; PULMONARY ARTERY; PULMONARY VEIN; REMODELING; SMOOTH MUSCLE FIBER; SPRAGUE DAWLEY RAT;

HIF-2Α; HYPOXIC PULMONARY HYPERTENSION; REMODELING; TRANSGELIN;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOOD PRESSURE; CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; HUMANS; HYPERTENSION, PULMONARY; MALE; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MYOCYTES, SMOOTH MUSCLE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PULMONARY ARTERY; PULMONARY VEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; RNA, SMALL INTERFERING; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84900036465     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00327.2013     Document Type: Article

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