STAT3-Mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious

Cancer Research

Volumn 74, Issue 9, 2014, Pages 2579-2590

  Maycotte, Paola ^a   Gearheart, Christy M ^b   Barnard, Rebecca ^c   Aryal, Suraj ^a   Levy, Jean M Mulcahy ^b   Fosmire, Susan P ^b   Hansen, Ryan J ^c   Morgan, Michael J ^a   Porter, Christopher C ^b   Gustafson, Daniel L ^c   Thorburn, Andrew ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Children's Hospital Colorado   (United States)

^c Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SHORT HAIRPIN RNA; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CANCER CLASSIFICATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; CHLOROQUINE; DOXORUBICIN; FEMALE; HUMANS; MEMBRANE PROTEINS; MICE; MICE, NUDE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA INTERFERENCE; RNA, SMALL INTERFERING; STAT3 TRANSCRIPTION FACTOR; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR BURDEN; UBIQUITIN-ACTIVATING ENZYMES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84900013820     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3470     Document Type: Article

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