Allosteric modulation of alpha4beta2 nicotinic acetylcholine receptors by HEPES

European Journal of Pharmacology

Volumn 732, Issue 1, 2014, Pages 159-168

  Weltzin, Maegan M ^a   Huang, Yanzhou ^a   Schulte, Marvin K ^a  

^a UNIVERSITY OF ALASKA FAIRBANKS   (United States)

Author keywords

Alpha4beta2; Alpha7; desformylflustrabromine; dFbr; HEPES; Ligand gated ion channels; Mutagenesis; Nicotinic acetylcholine receptor; Positive allosteric modulation; Two electrode voltage clamp

Indexed keywords

4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; ACETYLCHOLINE; BUNGAROTOXIN RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; BROMINATED HYDROCARBON; DESFORMYLFLUSTRABROMINE; INDOLE ALKALOID; NICOTINIC AGENT; NICOTINIC RECEPTOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; STOICHIOMETRY; VOLTAGE CLAMP TECHNIQUE; XENOPUS LAEVIS; ANIMAL; DRUG EFFECTS; FEMALE; HUMAN; METABOLISM; PATCH CLAMP TECHNIQUE;

ACETYLCHOLINE; ANIMALS; FEMALE; HEPES; HUMANS; HYDROCARBONS, BROMINATED; INDOLE ALKALOIDS; NICOTINIC AGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 84899981632     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.06.001     Document Type: Article

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