Subunit-dependent modulation of neuronal nicotinic receptors by zinc

Journal of Neuroscience

Volumn 21, Issue 6, 2001, Pages 1848-1856

  Hsiao, Bernard ^a   Dweck, David ^a   Luetje, Charles W ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Acetylcholine; Inhibition; Modulation; Neuronal nicotinic receptors; Potentiation; Zinc

Indexed keywords

ACETYLCHOLINE; CADMIUM; HISTIDINE; NICKEL; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; ZINC;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; XENOPUS LAEVIS;

EID: 0035869550     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-06-01848.2001     Document Type: Article

References (46)

1. Mechanism for modulation of nicotinic acetylcholine receptors that can influence synaptic transmission
2. Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure
3. 2+ from brain tissue during activity
4. Biphasic modulation of the strychnine-sensitive glycine receptor by zinc
5. Unusual pharmacology of (+)-tubocurarine with rat neuronal nicotinic acetylcholine receptors containing β4 subunits
6. The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit
7. Zinc potentiates ATP-activated currents in rat sympathetic neurons
8. Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions
9. Pentameric structure and subunit stoichiometry of a neuronal nicotinic ucetylcholine receptor
10. Nicotinic receptors at the amino acid level
11. 2+
12. Neuronal α-bungarotoxin receptors are α7 subunit homomers
13. A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is up-regulated by chronic nicotine treatment
14. Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat
15. Importance of zinc in the central nervous system: The zinc-containing neuron
16. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor
17. A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors
18. Subunit interactions in coordination of nickel in cyclic nucleotide-gated channels
19. Multiple determinants of dihydro-β-erythroidine sensitivity on rat neuronal nicotinic receptor α subunits
20. 2+ binding site on the human glycine receptor α1 subunit
21. Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor
22. Stimulation-induced uptake and release of zinc in hippocampal slices
23. Metal ions and synaptic transmission: Think zinc
24. A receptors
25. 2+ modulation of recombinant human inhibitory glycine receptors
26. The modification of histidine residues
27. Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones
28. Modification of histidyl residues in proteins with diethylpyrocarbonate
29. Calcium influx through nicotinic receptors in rat central neurons: Its relevance to cellular regulation
30. Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia
31. 2+ on wild and mutant neuronal α7 nicotinic receptors
32. High-affinity zinc inhibition of NMDA NR1-NR2A receptors
33. Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons
34. Physostigmine and galanthamine: Probes for a novel binding site on the α4β2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells
35. Individual rat intrinsic cardiac neurons display variable nicotinic pharmacologies and neuronal nAChR β subunit mRNA expression patterns
36. Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia
37. Zinc has opposite effects on NMDA and non-NMDA receptors expressed in Xenopus oocytes
38. Diversity in primary structure and function of neuronal nicotinic acetylcholine receptor channels
39. Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands
40. Stoichiometry and arrangement of subunits in rod cyclic nucleotide-gated channels
41. Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit
42. Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors
43. Expression of nicotinic acetylcholine receptor subtypes in brain and retina
44. Differential modulation by copper and zinc of P2X2 and P2X4 receptor function
45. Potentiation and inhibition of neuronal nicotinic receptors by atropine: Competitive and noncompetitive effects
46. 2+