Allosteric modulator desformylflustrabromine relieves the inhibition of α2β2 and α4β2 nicotinic acetylcholine receptors by β-amyloid 1-42 peptide

Journal of Molecular Neuroscience

Volumn 45, Issue 1, 2011, Pages 42-47

  Pandya, Anshul ^a   Yakel, Jerrel L ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alzheimer's disease (AD); Beta amyloid (A 1 42); Desformylflustrabromine (dFBr); Electrophysiology; Nicotinic acetylcholine receptors (nAChRs); Positive allosteric modulators (PAMs)

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BROMINE DERIVATIVE; CHOLINERGIC RECEPTOR; DESFORMYLFLUSTRABROMINE; ISOPROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ARTICLE; FEMALE; FROG; NONHUMAN; OOCYTE; RAT; RECEPTOR BLOCKING; XENOPUS;

ALLOSTERIC REGULATION; AMYLOID BETA-PEPTIDES; ANIMALS; FEMALE; HYDROCARBONS, BROMINATED; INDOLE ALKALOIDS; NICOTINIC ANTAGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; RATS; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 79960968745     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-011-9509-3     Document Type: Article

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