High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

Journal of Nutritional Biochemistry

Volumn 25, Issue 6, 2014, Pages 634-641

  Takalo, Mari ^a   Haapasalo, Annakaisa ^a   Martiskainen, Henna ^a   Kurkinen, Kaisa M A ^a   Koivisto, Henna ^a   Miettinen, Pasi ^a   Khandelwal, Vinoth K M ^a   Kemppainen, Susanna ^a   Kaminska, Dorota ^a   Mäkinen, Petra ^a   Leinonen, Ville ^a,b   Pihlajamäki, Jussi ^a,b   Soininen, Hilkka ^a,b   Laakso, Markku ^a   Tanila, Heikki ^a,b   Hiltunen, Mikko ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Alternative splicing; Alzheimer's disease; High fat diet; Tau; Type 2 diabetes

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; MESSENGER RNA; PROTEIN KINASE B; SOMATOMEDIN B; TAU PROTEIN; ANTIDIABETIC AGENT; MAPT PROTEIN, MOUSE;

ALTERNATIVE RNA SPLICING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN TISSUE; CONTROLLED STUDY; ENHANCER REGION; EXON; GENE EXPRESSION; GENE OVEREXPRESSION; GENOTYPE; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPID DIET; METABOLISM; MOUSE; MOUSE MODEL; NERVOUS SYSTEM INFLAMMATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE REPEAT; PHENOTYPE; REARING; SIGNAL TRANSDUCTION; TEMPORAL CORTEX; ADVERSE EFFECTS; AMINO ACID SEQUENCE; ANIMAL; ANIMAL BEHAVIOR; BLOOD; C57BL MOUSE; CHEMISTRY; COMPLICATION; CROSS BREEDING; DIABETES MELLITUS, TYPE 2; FEMALE; GENETICS; HYPERINSULINISM; NERVE CELL; TEMPORAL LOBE; TRANSGENIC MOUSE; UPREGULATION;

MUS;

ALTERNATIVE SPLICING; ALZHEIMER DISEASE; ANIMALS; BEHAVIOR, ANIMAL; CROSSES, GENETIC; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; FEMALE; HYPERGLYCEMIA; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; REPETITIVE SEQUENCES, AMINO ACID; TAU PROTEINS; TEMPORAL LOBE; UP-REGULATION;

EID: 84899924078     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2014.02.003     Document Type: Article

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