Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Codeluppi, Simone ^a   Fernandez Zafra, Teresa ^a   Sandor, Katalin ^a   Kjell, Jacob ^a   Liu, Qingsong ^b,c,d   Abrams, Mathew ^a   Olson, Lars ^a   Gray, Nathanael S ^b,c   Svensson, Camilla I ^a   Uhlén, Per ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; SYNAPTOPHYSIN; TORIN2; UNCLASSIFIED DRUG; MTOR PROTEIN, RAT; NERVE PROTEIN; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; HYPERSENSITIVITY; MALE; MECHANICAL HYPERSENSITIVITY; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SCAR; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; SECRETION (PROCESS); SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; CALCIUM SIGNALING; CELLS, CULTURED; GENE EXPRESSION REGULATION; INTERLEUKIN-6; MALE; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; TOR SERINE-THREONINE KINASES;

EID: 84899870506     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092649     Document Type: Article

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