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Volumn 960, Issue , 2014, Pages 116-125
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Simultaneous determination of two iridoid glycosides, two anthraquinones and four flavonoid glycosides of Zhi-Zi-Da-Huang decoction in rat plasma by UFLC-MS/MS: Application to a comparative pharmacokinetic study in normal and cholestatic liver injury rats
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Author keywords
Cholestatic liver injury; Pharmacokinetics; Rat plasma; UFLC MS MS; Zhi Zi Da Huang decoction
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Indexed keywords
BODY FLUIDS;
FLAVONOIDS;
KETONES;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
PHARMACOKINETICS;
RATS;
SUGARS;
LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;
LIVER INJURIES;
MULTIPLE-REACTION MONITORING MODES;
RAT PLASMA;
RELATIVE STANDARD DEVIATIONS;
SIMULTANEOUS DETERMINATIONS;
UFLC-MS/MS;
ZHI-ZI-DA-HUANG DECOCTION;
GLYCOSIDES;
2 PROPANOL;
ACETIC ACID ETHYL ESTER;
ACETONITRILE;
ANTHRAQUINONE DERIVATIVE;
AURANTIIN;
CHINESE DRUG;
EMODIN;
FLAVONOID GLYCOSIDE;
FORMIC ACID;
GENIPIN;
GENIPIN GENTIOBIOSIDE;
GENIPOSIDE;
HESPERIDIN;
IRIDOID;
NARIRUTIN;
NEOHESPERIDIN;
PAEONIFLORIN;
RHEIN;
UNCLASSIFIED DRUG;
WATER;
ZHI ZI DA HUANG DECOCTION;
FLAVONOID;
HERBACEOUS AGENT;
ACCURACY;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ARTICLE;
CHOLESTATIC LIVER INJURY;
COMPARATIVE STUDY;
CONTROLLED STUDY;
ELUTION;
FLOW RATE;
GRADIENT ELUTION;
IONIZATION;
LIMIT OF QUANTITATION;
LIQUID CHROMATOGRAPHY;
LIQUID LIQUID EXTRACTION;
LIVER INJURY;
MASS SPECTROMETRY;
NONHUMAN;
PLASMA;
PRIORITY JOURNAL;
RAT;
TANDEM MASS SPECTROMETRY;
ULTRAFAST LIQUID CHROMATOGRAPHY;
ANIMAL;
BLOOD;
CHEMISTRY;
DRUG STABILITY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
INTRAHEPATIC CHOLESTASIS;
MALE;
METABOLISM;
PROCEDURES;
REPRODUCIBILITY;
SENSITIVITY AND SPECIFICITY;
SPRAGUE DAWLEY RAT;
STATISTICAL MODEL;
ANIMALS;
ANTHRAQUINONES;
CHOLESTASIS, INTRAHEPATIC;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
DRUGS, CHINESE HERBAL;
FLAVONOIDS;
IRIDOID GLYCOSIDES;
LINEAR MODELS;
MALE;
RATS;
RATS, SPRAGUE-DAWLEY;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
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EID: 84899833125
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2014.04.031 Document Type: Article |
Times cited : (25)
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References (34)
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