Evaluation of the protective effect of Rhei Radix et Rhizoma against α-naphthylisothiocyanate induced liver injury based on metabolic profile of bile acids

Journal of Ethnopharmacology

Volumn 144, Issue 3, 2012, Pages 599-604

  Yang, Fan ^a   Xu, Ying ^a,b   Xiong, Aizhen ^a   He, Yugi ^c   Yang, Li ^a,b   Wan, Yu Jui Yvonne ^c   Wang, Zhengtao ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai R and D Center for Standardization of Chinese Medicines   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

naphthylisothiocyanate; Bile acids; Hepatoprotective effect; Multivariate statistical analysis; Rhei radix et Rhizoma; Rhubarb

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; GLYCOCHENODEOXYCHOLIC ACID; GLYCOCHOLIC ACID; RHUBARB EXTRACT; TAUROCHOLIC ACID; TAUROHYODESOXYCHOLIC ACID; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID METABOLISM; CONTROLLED STUDY; LIVER INJURY; LIVER PROTECTION; MALE; MASS SPECTROMETRY; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; RAT; RHIZOME; RHUBARB; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

1-NAPHTHYLISOTHIOCYANATE; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BILE ACIDS AND SALTS; BILIRUBIN; CHOLESTASIS; DRUG-INDUCED LIVER INJURY; MALE; PLANT EXTRACTS; PLANT ROOTS; PROTECTIVE AGENTS; RATS; RATS, WISTAR; RHEUM; RHIZOME;

RHEUM X HYBRIDUM;

EID: 84870302967     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.09.049     Document Type: Article

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