-
1
-
-
0035830498
-
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae
-
Myung K, Datta A, Kolodner RD (2001) Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 104: 397-408.
-
(2001)
Cell
, vol.104
, pp. 397-408
-
-
Myung, K.1
Datta, A.2
Kolodner, R.D.3
-
2
-
-
58549092765
-
Mechanisms of dealing with DNA damage-induced replication problems
-
Budzowska M, Kanaar R (2009) Mechanisms of dealing with DNA damage-induced replication problems. Cell Biochem Biophys 53: 17-31.
-
(2009)
Cell Biochem Biophys
, vol.53
, pp. 17-31
-
-
Budzowska, M.1
Kanaar, R.2
-
3
-
-
0034102337
-
ATR disruption leads to chromosomal fragmentation and early embryonic lethality
-
Brown EJ, Baltimore D (2000) ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev 14: 397-402.
-
(2000)
Genes Dev
, vol.14
, pp. 397-402
-
-
Brown, E.J.1
Baltimore, D.2
-
4
-
-
0034177408
-
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
-
de Klein A, Muijtjens M, van Os R, Verhoeven Y, Smit B, et al. (2000) Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr Biol 10: 479-482.
-
(2000)
Curr Biol
, vol.10
, pp. 479-482
-
-
De Klein, A.1
Muijtjens, M.2
Van Os, R.3
Verhoeven, Y.4
Smit, B.5
-
5
-
-
3543079922
-
Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation
-
Garg R, Callens S, Lim DS, Canman CE, Kastan MB, et al. (2004) Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation. Mol Cancer Res 2: 362-369.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 362-369
-
-
Garg, R.1
Callens, S.2
Lim, D.S.3
Canman, C.E.4
Kastan, M.B.5
-
6
-
-
0033637170
-
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
-
Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, et al. (2000) Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev 14: 2989-3002.
-
(2000)
Genes Dev
, vol.14
, pp. 2989-3002
-
-
Tibbetts, R.S.1
Cortez, D.2
Brumbaugh, K.M.3
Scully, R.4
Livingston, D.5
-
7
-
-
0035797383
-
The DNA replication checkpoint response stabilizes stalled replication forks
-
Lopes M, Cotta-Ramusino C, Pellicioli A, Liberi G, Plevani P, et al. (2001) The DNA replication checkpoint response stabilizes stalled replication forks. Nature 412: 557-561.
-
(2001)
Nature
, vol.412
, pp. 557-561
-
-
Lopes, M.1
Cotta-Ramusino, C.2
Pellicioli, A.3
Liberi, G.4
Plevani, P.5
-
8
-
-
0037178723
-
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
-
Cha RS, Kleckner N (2002) ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 297: 602-606.
-
(2002)
Science
, vol.297
, pp. 602-606
-
-
Cha, R.S.1
Kleckner, N.2
-
9
-
-
0037335861
-
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
-
Brown EJ, Baltimore D (2003) Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Genes Dev 17: 615-628.
-
(2003)
Genes Dev
, vol.17
, pp. 615-628
-
-
Brown, E.J.1
Baltimore, D.2
-
10
-
-
34249945536
-
DNA double-strand break repair: From mechanistic understanding to cancer treatment
-
Helleday T, Lo J, van Gent DC, Engelward BP (2007) DNA double-strand break repair: from mechanistic understanding to cancer treatment. DNA Repair (Amst) 6: 923-935.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 923-935
-
-
Helleday, T.1
Lo, J.2
Van Gent, D.C.3
Engelward, B.P.4
-
11
-
-
0037435026
-
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle
-
Pichierri P, Rosselli F, Franchitto A (2003) Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle. Oncogene 22: 1491-1500.
-
(2003)
Oncogene
, vol.22
, pp. 1491-1500
-
-
Pichierri, P.1
Rosselli, F.2
Franchitto, A.3
-
12
-
-
1642458364
-
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest
-
Davies SL, North PS, Dart A, Lakin ND, Hickson ID (2004) Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Mol Cell Biol 24: 1279-1291.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1279-1291
-
-
Davies, S.L.1
North, P.S.2
Dart, A.3
Lakin, N.D.4
Hickson, I.D.5
-
13
-
-
3042597013
-
Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases
-
Li W, Kim SM, Lee J, Dunphy WG (2004) Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases. J Cell Biol 165: 801-812.
-
(2004)
J Cell Biol
, vol.165
, pp. 801-812
-
-
Li, W.1
Kim, S.M.2
Lee, J.3
Dunphy, W.G.4
-
14
-
-
25444462208
-
Fhit and CHK1 have opposing effects on homologous recombination repair
-
Hu B, Wang H, Wang X, Lu HR, Huang C, et al. (2005) Fhit and CHK1 have opposing effects on homologous recombination repair. Cancer Res 65: 8613-8616.
-
(2005)
Cancer Res
, vol.65
, pp. 8613-8616
-
-
Hu, B.1
Wang, H.2
Wang, X.3
Lu, H.R.4
Huang, C.5
-
15
-
-
13944266820
-
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
-
Sorensen CS, Hansen LT, Dziegielewski J, Syljuasen RG, Lundin C, et al. (2005) The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat Cell Biol 7: 195-201.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 195-201
-
-
Sorensen, C.S.1
Hansen, L.T.2
Dziegielewski, J.3
Syljuasen, R.G.4
Lundin, C.5
-
16
-
-
33748065304
-
Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition
-
McCabe N, Turner NC, Lord CJ, Kluzek K, Bialkowska A, et al. (2006) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. Cancer Res 66: 8109-8115.
-
(2006)
Cancer Res
, vol.66
, pp. 8109-8115
-
-
McCabe, N.1
Turner, N.C.2
Lord, C.J.3
Kluzek, K.4
Bialkowska, A.5
-
17
-
-
4944257913
-
ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining
-
Wang H, Wang H, Powell SN, Iliakis G, Wang Y (2004) ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining. Cancer Res 64: 7139-7143.
-
(2004)
Cancer Res
, vol.64
, pp. 7139-7143
-
-
Wang, H.1
Wang, H.2
Powell, S.N.3
Iliakis, G.4
Wang, Y.5
-
18
-
-
65549088533
-
ATR and H2AX cooperate in maintaining genome stability under replication stress
-
Chanoux RA, Yin B, Urtishak KA, Asare A, Bassing CH, et al. (2009) ATR and H2AX cooperate in maintaining genome stability under replication stress. J Biol Chem 284: 5994-6003.
-
(2009)
J Biol Chem
, vol.284
, pp. 5994-6003
-
-
Chanoux, R.A.1
Yin, B.2
Urtishak, K.A.3
Asare, A.4
Bassing, C.H.5
-
19
-
-
0035088810
-
The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pH
-
Brilliant MH (2001) The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pH. Pigment Cell Res 14: 86-93.
-
(2001)
Pigment Cell Res
, vol.14
, pp. 86-93
-
-
Brilliant, M.H.1
-
20
-
-
0026431967
-
Direct molecular identification of the mouse pink-eyed unstable mutation by genome scanning
-
Brilliant MH, Gondo Y, Eicher EM (1991) Direct molecular identification of the mouse pink-eyed unstable mutation by genome scanning. Science 252: 566-569.
-
(1991)
Science
, vol.252
, pp. 566-569
-
-
Brilliant, M.H.1
Gondo, Y.2
Eicher, E.M.3
-
21
-
-
0032913013
-
Molecular basis of albinism: Mutations and polymorphisms of pigmentation genes associated with albinism
-
Oetting WS, King RA (1999) Molecular basis of albinism: mutations and polymorphisms of pigmentation genes associated with albinism. Hum Mutat 13: 99-115.
-
(1999)
Hum Mutat
, vol.13
, pp. 99-115
-
-
Oetting, W.S.1
King, R.A.2
-
22
-
-
0028978607
-
On the mechanism of UV and gamma-ray-induced intrachromosomal recombination in yeast cells synchronized in different stages of the cell cycle
-
Galli A, Schiestl RH (1995) On the mechanism of UV and gamma-ray-induced intrachromosomal recombination in yeast cells synchronized in different stages of the cell cycle. Mol Gen Genet 248: 301-310.
-
(1995)
Mol Gen Genet
, vol.248
, pp. 301-310
-
-
Galli, A.1
Schiestl, R.H.2
-
23
-
-
84887199705
-
Induction of homologous recombination following in utero exposure to DNA-damaging agents
-
Karia B, Martinez JA, Bishop AJ (2013) Induction of homologous recombination following in utero exposure to DNA-damaging agents. DNA Repair (Amst).
-
(2013)
DNA Repair (Amst)
-
-
Karia, B.1
Martinez, J.A.2
Bishop, A.J.3
-
24
-
-
80052341227
-
A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes
-
Brown AD, Claybon AB, Bishop AJ (2011) A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes. Mol Cell Biol 31: 3593-3602.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3593-3602
-
-
Brown, A.D.1
Claybon, A.B.2
Bishop, A.J.3
-
25
-
-
78649831343
-
PARP1 suppresses homologous recombination events in mice in vivo
-
Claybon A, Karia B, Bruce C, Bishop AJ (2010) PARP1 suppresses homologous recombination events in mice in vivo. Nucleic Acids Res 38: 7538-7545.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 7538-7545
-
-
Claybon, A.1
Karia, B.2
Bruce, C.3
Bishop, A.J.4
-
26
-
-
33646068370
-
Assembly of the brainstem cochlear nuclear complex is revealed by intersectional and subtractive genetic fate maps
-
Farago AF, Awatramani RB, Dymecki SM (2006) Assembly of the brainstem cochlear nuclear complex is revealed by intersectional and subtractive genetic fate maps. Neuron 50: 205-218.
-
(2006)
Neuron
, vol.50
, pp. 205-218
-
-
Farago, A.F.1
Awatramani, R.B.2
Dymecki, S.M.3
-
27
-
-
85047656203
-
Dissection of a mouse eye for a whole mount of the retinal pigment epithelium
-
Claybon A, Bishop AJ (2011) Dissection of a mouse eye for a whole mount of the retinal pigment epithelium. J Vis Exp.
-
(2011)
J Vis Exp
-
-
Claybon, A.1
Bishop, A.J.2
-
28
-
-
0035070264
-
Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice
-
Bishop AJ, Kosaras B, Carls N, Sidman RL, Schiestl RH (2001) Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice. Carcinogenesis 22: 641-649.
-
(2001)
Carcinogenesis
, vol.22
, pp. 641-649
-
-
Bishop, A.J.1
Kosaras, B.2
Carls, N.3
Sidman, R.L.4
Schiestl, R.H.5
-
29
-
-
82755183606
-
Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context
-
Gunn A, Bennardo N, Cheng A, Stark JM (2011) Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context. J Biol Chem 286: 42470-42482.
-
(2011)
J Biol Chem
, vol.286
, pp. 42470-42482
-
-
Gunn, A.1
Bennardo, N.2
Cheng, A.3
Stark, J.M.4
-
30
-
-
0033569684
-
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
-
Pierce AJ, Johnson RD, Thompson LH, Jasin M (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev 13: 2633-2638.
-
(1999)
Genes Dev
, vol.13
, pp. 2633-2638
-
-
Pierce, A.J.1
Johnson, R.D.2
Thompson, L.H.3
Jasin, M.4
-
31
-
-
34249885603
-
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss
-
Ruzankina Y, Pinzon-Guzman C, Asare A, Ong T, Pontano L, et al. (2007) Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell 1: 113-126.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 113-126
-
-
Ruzankina, Y.1
Pinzon-Guzman, C.2
Asare, A.3
Ong, T.4
Pontano, L.5
-
32
-
-
0036240961
-
Site-specific somatic mutagenesis in the retinal pigment epithelium
-
Mori M, Metzger D, Garnier JM, Chambon P, Mark M (2002) Site-specific somatic mutagenesis in the retinal pigment epithelium. Invest Ophthalmol Vis Sci 43: 1384-1388.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 1384-1388
-
-
Mori, M.1
Metzger, D.2
Garnier, J.M.3
Chambon, P.4
Mark, M.5
-
33
-
-
0141816840
-
Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development
-
Bishop AJ, Hollander MC, Kosaras B, Sidman RL, Fornace AJ Jr., et al. (2003) Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res 63: 5335-5343.
-
(2003)
Cancer Res
, vol.63
, pp. 5335-5343
-
-
Bishop, A.J.1
Hollander, M.C.2
Kosaras, B.3
Sidman, R.L.4
Fornace Jr., A.J.5
-
34
-
-
11044234004
-
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway
-
Alderton GK, Joenje H, Varon R, Borglum AD, Jeggo PA, et al. (2004) Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. Hum Mol Genet 13: 3127-3138.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 3127-3138
-
-
Alderton, G.K.1
Joenje, H.2
Varon, R.3
Borglum, A.D.4
Jeggo, P.A.5
-
35
-
-
33745200945
-
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2
-
Xia B, Sheng Q, Nakanishi K, Ohashi A, Wu J, et al. (2006) Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell 22: 719-729.
-
(2006)
Mol Cell
, vol.22
, pp. 719-729
-
-
Xia, B.1
Sheng, Q.2
Nakanishi, K.3
Ohashi, A.4
Wu, J.5
-
36
-
-
84863415403
-
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair
-
Polo SE, Blackford AN, Chapman JR, Baskcomb L, Gravel S, et al. (2012) Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair. Mol Cell 45: 505-516.
-
(2012)
Mol Cell
, vol.45
, pp. 505-516
-
-
Polo, S.E.1
Blackford, A.N.2
Chapman, J.R.3
Baskcomb, L.4
Gravel, S.5
-
37
-
-
0034650582
-
Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice
-
Bishop AJ, Barlow C, Wynshaw-Boris AJ, Schiestl RH (2000) Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice. Cancer Res 60: 395-399.
-
(2000)
Cancer Res
, vol.60
, pp. 395-399
-
-
Bishop, A.J.1
Barlow, C.2
Wynshaw-Boris, A.J.3
Schiestl, R.H.4
-
38
-
-
0346729824
-
Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice
-
Reliene R, Bishop AJ, Li G, Schiestl RH (2004) Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst) 3: 103-111.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 103-111
-
-
Reliene, R.1
Bishop, A.J.2
Li, G.3
Schiestl, R.H.4
-
39
-
-
23344444636
-
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
-
Saleh-Gohari N, Bryant HE, Schultz N, Parker KM, Cassel TN, et al. (2005) Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol Cell Biol 25: 7158-7169.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7158-7169
-
-
Saleh-Gohari, N.1
Bryant, H.E.2
Schultz, N.3
Parker, K.M.4
Cassel, T.N.5
-
40
-
-
84859047067
-
Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination
-
Yeung PL, Denissova NG, Nasello C, Hakhverdyan Z, Chen JD, et al. (2012) Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination. J Cell Biochem 113: 1787-1799.
-
(2012)
J Cell Biochem
, vol.113
, pp. 1787-1799
-
-
Yeung, P.L.1
Denissova, N.G.2
Nasello, C.3
Hakhverdyan, Z.4
Chen, J.D.5
-
41
-
-
84889563685
-
ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA
-
Toledo LI, Altmeyer M, Rask MB, Lukas C, Larsen DH, et al. (2013) ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA. Cell 155: 1088-1103.
-
(2013)
Cell
, vol.155
, pp. 1088-1103
-
-
Toledo, L.I.1
Altmeyer, M.2
Rask, M.B.3
Lukas, C.4
Larsen, D.H.5
-
42
-
-
0029768921
-
Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells
-
Park MS, Ludwig DL, Stigger E, Lee SH (1996) Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells. J Biol Chem 271: 18996-19000.
-
(1996)
J Biol Chem
, vol.271
, pp. 18996-19000
-
-
Park, M.S.1
Ludwig, D.L.2
Stigger, E.3
Lee, S.H.4
-
43
-
-
30344455023
-
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7
-
Friedberg EC, Meira LB (2006) Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7. DNA Repair (Amst) 5: 189-209.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 189-209
-
-
Friedberg, E.C.1
Meira, L.B.2
-
44
-
-
84860239954
-
Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse
-
Thanos A, Morizane Y, Murakami Y, Giani A, Mantopoulos D, et al. (2012) Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse. Am J Pathol 180: 1917-1927.
-
(2012)
Am J Pathol
, vol.180
, pp. 1917-1927
-
-
Thanos, A.1
Morizane, Y.2
Murakami, Y.3
Giani, A.4
Mantopoulos, D.5
-
45
-
-
0035979247
-
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells
-
Loonstra A, Vooijs M, Beverloo HB, Allak BA, van Drunen E, et al. (2001) Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells. Proc Natl Acad Sci U S A 98: 9209-9214.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9209-9214
-
-
Loonstra, A.1
Vooijs, M.2
Beverloo, H.B.3
Allak, B.A.4
Van Drunen, E.5
-
46
-
-
84888437263
-
ATR activates the S-M checkpoint during unperturbed growth to ensure sufficient replication prior to mitotic onset
-
Eykelenboom JK, Harte EC, Canavan L, Pastor-Peidro A, Calvo-Asensio I, et al. (2013) ATR activates the S-M checkpoint during unperturbed growth to ensure sufficient replication prior to mitotic onset. Cell Rep 5: 1095-1107.
-
(2013)
Cell Rep
, vol.5
, pp. 1095-1107
-
-
Eykelenboom, J.K.1
Harte, E.C.2
Canavan, L.3
Pastor-Peidro, A.4
Calvo-Asensio, I.5
-
47
-
-
0345073699
-
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
-
O'Driscoll M, Ruiz-Perez VL, Woods CG, Jeggo PA, Goodship JA (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet 33: 497-501.
-
(2003)
Nat Genet
, vol.33
, pp. 497-501
-
-
O'Driscoll, M.1
Ruiz-Perez, V.L.2
Woods, C.G.3
Jeggo, P.A.4
Goodship, J.A.5
|