Crosstalk and competition in signaling networks

Biophysical Journal

Volumn 103, Issue 11, 2012, Pages 2389-2398

  Rowland, Michael A ^a   Fontana, Walter ^b   Deeds, Eric J ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MULTIENZYME COMPLEX;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL COMMUNICATION; COMPUTER SIMULATION; HUMAN; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL COMMUNICATION; COMPUTER SIMULATION; HUMANS; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; SIGNAL TRANSDUCTION;

EID: 84870539840     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.10.006     Document Type: Article

References (49)

1. B.J. Mayer, M.L. Blinov, and L.M. Loew Molecular machines or pleiomorphic ensembles: signaling complexes revisited J. Biol. 8 2009 81
2. M. Thomson, and J. Gunawardena Unlimited multistability in multisite phosphorylation systems Nature 460 2009 274 277
3. D. Danielpour, and K. Song Cross-talk between IGF-I and TGF-β signaling pathways Cytokine Growth Factor Rev. 17 2006 59 74
4. S.M. Hill Receptor crosstalk: communication through cell signaling pathways Anat. Rec. 253 1998 42 48
5. D. Javelaud, and A. Mauviel Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: implications for carcinogenesis Oncogene 24 2005 5742 5750
6. M.R. Junttila, S.P. Li, and J. Westermarck Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival FASEB J. 22 2008 954 965
7. Q.H. Liu, and P.A. Hofmann Protein phosphatase 2A-mediated cross-talk between p38 MAPK and ERK in apoptosis of cardiac myocytes Am. J. Physiol. Heart Circ. Physiol. 286 2004 H2204 H2212
8. D.P. Brazil, and B.A. Hemmings Ten years of protein kinase B signalling: a hard Akt to follow Trends Biochem. Sci. 26 2001 657 664
9. G. MacBeath Protein microarrays and proteomics Nat. Genet. 32 Suppl 2002 526 532
10. D.M. Virshup, and S. Shenolikar From promiscuity to precision: protein phosphatases get a makeover Mol. Cell 33 2009 537 545
11. B.P. Eliceiri Integrin and growth factor receptor crosstalk Circ. Res. 89 2001 1104 1110
12. C. Gomez-Uribe, G.C. Verghese, and L.A. Mirny Operating regimes of signaling cycles: statics, dynamics, and noise filtering PLOS Comput. Biol. 3 2007 e246
13. M. Behar, H.G. Dohlman, and T.C. Elston Kinetic insulation as an effective mechanism for achieving pathway specificity in intracellular signaling networks Proc. Natl. Acad. Sci. USA 104 2007 16146 16151
14. Y. Kim, and Z. Paroush S.Y. Shvartsman Substrate-dependent control of MAPK phosphorylation in vivo Mol. Syst. Biol. 7 2011 467
15. M.N. McClean, and A. Mody S. Ramanathan Cross-talk and decision making in MAP kinase pathways Nat. Genet. 39 2007 409 414
16. S.Y. Kim, and J.E. Ferrell Jr. Substrate competition as a source of ultrasensitivity in the inactivation of Wee1 Cell 128 2007 1133 1145
17. A. Belle, and A. Tanay E.K. O'Shea Quantification of protein half-lives in the budding yeast proteome Proc. Natl. Acad. Sci. USA 103 2006 13004 13009
18. A. Goldbeter, and D.E. Koshland Jr. An amplified sensitivity arising from covalent modification in biological systems Proc. Natl. Acad. Sci. USA 78 1981 6840 6844
19. C.P. Bagowski, J. Besser, C.R. Frey, and J.E. Ferrell Jr. The JNK cascade as a biochemical switch in mammalian cells: ultrasensitive and all-or-none responses Curr. Biol. 13 2003 315 320
20. D.G. Hardie, and I.P. Salt S.P. Davies AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge Biochem. J. 338 1999 717 722
21. C.Y. Huang, and J.E. Ferrell Jr. Ultrasensitivity in the mitogen-activated protein kinase cascade Proc. Natl. Acad. Sci. USA 93 1996 10078 10083
22. D.C. LaPorte, and D.E. Koshland Jr. Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation Nature 305 1983 286 290
23. M.H. Meinke, J.S. Bishop, and R.D. Edstrom Zero-order ultrasensitivity in the regulation of glycogen phosphorylase Proc. Natl. Acad. Sci. USA 83 1986 2865 2868
24. J. Zhang, P.L. Yang, and N.S. Gray Targeting cancer with small molecule kinase inhibitors Nat. Rev. Cancer 9 2009 28 39
25. A.C. Hindmarsh, and P.N. Brown C.S. Woodward SUNDIALS: suite of nonlinear and differential/algebraic equation solvers ACM Trans. Math. Software 31 2005 363 396
26. R.L. Khandelwal, J.R. Vandenheede, and E.G. Krebs Purification, properties, and substrate specificities of phosphoprotein phosphatase(s) from rabbit liver J. Biol. Chem. 251 1976 4850 4858
27. Y. Radhakrishnan, and W.H. Busby Jr. D.R. Clemmons Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells J. Biol. Chem. 285 2010 15682 15695
28. D. Voet, and J.G. Voet Biochemistry 2011 John Wiley & Sons Hoboken, NJ
29. J. Gunawardena Multisite protein phosphorylation makes a good threshold but can be a poor switch Proc. Natl. Acad. Sci. USA 102 2005 14617 14622
30. N.I. Markevich, J.B. Hoek, and B.N. Kholodenko Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades J. Cell Biol. 164 2004 353 359
31. J.A. Ubersax, and E.L. Woodbury D.O. Morgan Targets of the cyclin-dependent kinase Cdk1 Nature 425 2003 859 864
32. J. Ptacek, and G. Devgan M. Snyder Global analysis of protein phosphorylation in yeast Nature 438 2005 679 684
33. A. Kaushansky, and A. Gordus G. MacBeath System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties Chem. Biol. 15 2008 808 817
34. T. Hunter The age of crosstalk: phosphorylation, ubiquitination, and beyond Mol. Cell 28 2007 730 738
35. S. Arena, S. Benvenuti, and A. Bardelli Genetic analysis of the kinome and phosphatome in cancer Cell. Mol. Life Sci. 62 2005 2092 2099
36. G. Manning, and D.B. Whyte S. Sudarsanam The protein kinase complement of the human genome Science 298 2002 1912 1934
37. C. Walsh Posttranslational Modification of Proteins: Expanding Nature's Inventory 2006 Roberts and Co. Publishers Greenwood Village, CO
38. B.N. Kholodenko Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades Eur. J. Biochem. 267 2000 1583 1588
39. B. Schoeberl, and C. Eichler-Jonsson G. Müller Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors Nat. Biotechnol. 20 2002 370 375
40. D. Shao, and W. Zheng C. Tang Dynamic studies of scaffold-dependent mating pathway in yeast Biophys. J. 91 2006 3986 4001
41. D.L. Nelson, A.L. Lehninger, and M.M. Cox Lehninger Principles of Biochemistry 2008 W.H. Freeman New York
42. J.A. Wells, and C.L. McClendon Reaching for high-hanging fruit in drug discovery at protein-protein interfaces Nature 450 2007 1001 1009
43. Wolfram Research Mathematica 2010 Wolfram Research Champaign, IL
44. M. Loog, and D.O. Morgan Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates Nature 434 2005 104 108
45. Z. Yan, and S.A. Fedorov R.S. Williams PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells Mol. Cell. Biol. 20 2000 1021 1029
46. E.L. Woodbury, and D.O. Morgan Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase Nat. Cell Biol. 9 2007 106 112
47. J. Bloom, and I.M. Cristea F.R. Cross Global analysis of Cdc14 phosphatase reveals diverse roles in mitotic processes J. Biol. Chem. 286 2011 5434 5445
48. D. Matheos, and M. Metodiev M.D. Rose Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p J. Cell Biol. 165 2004 99 109
49. J.M. Enserink, and R.D. Kolodner An overview of Cdk1-controlled targets and processes Cell Div. 5 2010 11