Fluoride and arsenic exposure impairs learning and memory and decreases mGluR5 expression in the hippocampus and cortex in rats

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Jiang, Shoufang ^a,b   Su, Jing ^b   Yao, Sanqiao ^b   Zhang, Yanshu ^b   Cao, Fuyuan ^b   Wang, Fei ^a   Wang, Huihui ^a   Li, Jun ^b   Xi, Shuhua ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b HEBEI UNITED UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC; ARSENITE SODIUM; FLUORIDE; MESSENGER RNA; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; SODIUM FLUORIDE; ARSENOUS ACID DERIVATIVE; GLUTAMIC ACID; GRM5 PROTEIN, RAT; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR; SODIUM DERIVATIVE; WATER POLLUTANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN FUNCTION; CONTROLLED STUDY; DISEASE ACTIVITY; GENE EXPRESSION; GROWTH RATE; HIPPOCAMPUS; IN VIVO STUDY; LEARNING DISORDER; MALE; MEMORY DISORDER; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPATIAL LEARNING; SPATIAL MEMORY; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; BLOOD; DRUG EFFECTS; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; MAZE TEST; METABOLISM; SPRAGUE DAWLEY RAT; WATER POLLUTANT;

ANIMALS; ARSENITES; CEREBRAL CORTEX; DRUG SYNERGISM; GENE EXPRESSION REGULATION; GLUTAMIC ACID; HIPPOCAMPUS; MAZE LEARNING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, METABOTROPIC GLUTAMATE 5; RECEPTORS, METABOTROPIC GLUTAMATE; SODIUM COMPOUNDS; SODIUM FLUORIDE; SPATIAL MEMORY; WATER POLLUTANTS, CHEMICAL;

EID: 84899758176     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096041     Document Type: Article

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