Arsenic speciation transported through the placenta from mother mice to their newborn pups

Environmental Research

Volumn 101, Issue 3, 2006, Pages 349-355

  Jin, Yaping ^a   Xi, Shuhua ^b   Li, Xin ^a   Lu, Chunwei ^a   Li, Gexin ^a   Xu, Yuanyuan ^a   Qu, Chunqing ^a   Niu, Yuhong ^a   Sun, Guifan ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SHENYANG MEDICAL COLLEGE   (China)

Author keywords

Arsenate; Arsenic species; Arsenite; Disposition; Metabolism; Methylation; Mice; Repeated exposure

Indexed keywords

ARSENIC; CACODYLIC ACID; DRINKING WATER; METHANEARSONIC ACID; TRIMETHYLARSINE OXIDE;

ARSENIC; BIOTRANSFORMATION; BRAIN; DRINKING WATER; HEALTH IMPACT; POLLUTION; SMALL MAMMAL;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; GESTATIONAL AGE; LIPID BILAYER; LIPID SOLUBILITY; LIVER; LIVER METABOLISM; MOUSE; NEWBORN; NONHUMAN; PLACENTAL TRANSFER; PRIORITY JOURNAL; SPECIES DIFFERENTIATION; TISSUE DISTRIBUTION; TISSUE LEVEL; TISSUE SECTION; VERTICAL TRANSMISSION;

ANIMALS; ANIMALS, NEWBORN; ARSENIC; ARSENICALS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN CHEMISTRY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; FEMALE; LIVER; MATERNAL-FETAL EXCHANGE; MICE; PLACENTA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RANDOM ALLOCATION; TISSUE DISTRIBUTION; WATER POLLUTANTS, CHEMICAL;

EID: 33646864496     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2005.11.006     Document Type: Article

References (40)

1. Anderson L.M., Diwan B.A., Fear N.T., and Roman E. Critical windows of exposure for children's health: cancer in human epidemiological studies and neoplasm in experimental animal models. Environ. Health Perspect. 108 Suppl. 3 (2000) 573-594
2. Aposhian H.V. Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity. Annu. Rev. Pharmacol. Toxicol. 37 (1997) 397-419
3. Buchet J.P., Lauwerys R., and Roels H. Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethyarsenate, or dimethylarsenate in man. Int. Arch. Occup. Environ. Health 48 (1981) 71-79
4. Chattopadhyay S., Bhaumik S., NagChaudhury A., and Das Gupta S. Arsenic induced changes in growth development and apoptosis in neonatal and adult brain cells in vivo and in tissue culture. Toxicol. Lett. 128 (2002) 73-84
5. Concha G., Vogler G., Lezcano D., Nermell B., and Vahter M. Exposure to inorganic arsenic metabolites during early human development. Toxicol. Sci. 44 (1998) 185-190
6. Cui X., Kobayashi Y., Hayakawa T., and Hirano S. Arsenic speciation in bile and urine following oral and intravenous exposure to inorganic and organic arsenics in rats. Toxicol. Sci. 82 (2004) 478-487
7. Cullen W.R., and Reimer K.J. Arsenic speciation in the environment. Chem. Rev. 89 (1989) 713-764
8. Dopp E., Hartmann L.M., Florea A.M., et al. Uptake of inorganic and organic derivatives of arsenic associated with induced cytotoxic and genotoxic effects in Chinese hamster ovary (CHO) cells. Toxicol. Appl. Pharmacol. 201 (2004) 156-165
9. Fujino Y., Guo X., Liu J., et al. Mental health burden amongst inhabitants of an arsenic affected area in Inner Mongolia, China. Soc. Sci. Med. 59 (2004) 1969-1973
10. Hughes M.F., Kenynon E.M., Edwards B.C., Mitchell C.T., Del Razo L.M., and Thomas D.J. Accumulation and metabolism of arsenic in mice after repeated oral administration of arsenate. Toxicol. Appl. Pharmacol. 191 (2003) 202-210
11. Jin Y.P., Sun G.F., Li X., et al. Study on the toxic effects induced by different arsenicals in primary cultured rat astroglia. Toxicol. Appl. Pharmacol. 196 (2004) 396-403
12. Kenyon E.M., Del Razo L.M., and Hughes M.F. Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in mice following acute oral administration of arsenate. Toxicol. Sci. 85 (2005) 468-475
13. Kenyon E.M., Del Razo L.M., Hughes M.F., and Kitchin K.T. An integrated pharmacokinetic and pharmacodynamic study of arsenite action. 2. Heme oxygenase induction in mice. Toxicology 206 (2005) 389-401
14. Kitchin K.T. Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites. Toxicol. Appl. Pharmacol. 172 (2001) 249-261
15. Kitchin K.T., Del Razo L.M., Brown J.M., Anderson W.L., and Kenyon E.M. An integrated pharmacokinetic and pharmacodynamic study of arsenite action. Teratog. Carcinog. Mutagen. 19 (1999) 385-402
16. Mandal B.K., Ogra Y., Anzai K., and Suzuki K.T. Speciation of arsenic in biological samples. Toxicol. Appl. Pharmacol. 198 (2004) 307-318
17. Mass M.J., Tennant A., Roop B.C., et al. Methylated trivalent arsenic species are genotoxic. Chem. Res. Toxicol. 14 (2001) 355-361
18. Morikawa T., Wanibuchi H., Morimura K., Ogawa M., and Fukushima S. Promotion of skin carcinogenesis by dimethylarsinic acid in keratin (K6)/ODC transgenic mice. Jpn. J. Cancer Res. 91 (2000) 579-581
19. Namgung U., and Xia Z. Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases. Toxicol. Appl. Pharmacol. 174 (2001) 130-138
20. Petrick J.S., Ayala-Fierro F., Cullen W.R., Carter D.E., and Aposhian H.V. Mono-methylarsonous acid (MMA(III)) is more toxic than arsenite in Chang human hepatocytes. Toxicol. Appl. Pharmacol. 163 (2000) 203-207
21. Petrick J.S., Jagadish B., Mash E.A., and Aposhian H.V. Monomethylarsonous acid (MMAIII) and arsenite: LD50 in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chem. Res. Toxicol. 14 (2001) 651-656
22. Pott W.A., Benjamin S.A., and Yang R.S.H. Pharmacokinetics, metabolism and carcinogenicity of arsenic. Rev. Environ. Contam. Toxicol. 169 (2001) 165-214
23. Rodriguez V.M., Del Razo L.M., Limon-Pacheco J.H., and Giordano M. Glutathione reductase inhibition and methylated arsenic distribution in Cd1 mice brain and liver. Toxicol. Sci. 84 (2005) 157-166
24. Salim E.I., Wanibuchi H., Morimura K., Wei M., et al. Carcinogenicity of dimethylarsinic acid in p53 heterozygous knockout and wild-type C57BL/6J mice. Carcinogenesis 24 (2003) 335-342
25. Styblo M., Yamauchi H., and Thomas D.J. Comparative in vitro methylation of trivalent and pentavalent arsenicals. Toxicol. Appl. Pharmacol. 135 (1995) 172-178
26. Styblo M., Del Razo L.M., Vega L., Germolec D.R., LeCluyse E.L., Hamilton G.A., Wang C., Cullen W.R., and Thomas D.J. Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in human cells. Arch. Toxicol. 74 (2000) 289-299
27. Thomas D.J., Styblo M., and Lin S. The cellular metabolism and systemic toxicity of arsenic. Toxicol. Appl. Pharmacol. 176 (2001) 127-144
28. Thomas D.J., Waters S.B., and Styblo M. Elucidating the pathway for arsenic methylation. Toxicol. Appl. Pharmacol. 198 (2004) 319-326
29. Tomatis L., Narod S., and Yamasaki H. Transgeneration transmission of carcinogenic risk. Carcinogenesis 13 (1992) 145-151
30. Tsuji J.S., Benson R., Schoof R.A., and Hook G.C. Health effect levels for risk assessment of childhood exposure to arsenic. Regul. Toxicol. Pharmacol. 39 (2004) 99-110
31. Vahter M., and Marafante E. Intracellular interaction and metabolic fate of arsenite and arsenate in mice and rabbits. Chem. Biol. Interact. 47 (1983) 29-44
32. Vega L., Styblo M., Patterson R., Cullen W., Wang C., and Germolec D. Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes. Toxicol. Appl. Phramacol. 172 (2001) 225-232
33. Waalkes M.P., Ward J.M., Liu J., and Diwan B.A. Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in mice. Toxicol. Appl. Pharmacol. 186 (2003) 7-17
34. Waalkes M.P., Liu J., Ward J.M., and Diwan B.A. Mechanisms underlying arsenic carcinogenesis: hypersensitivity of mice exposed to inorganic arsenic during gestation. Toxicology 198 (2004) 31-38
35. Wasserman G.A., Liu X., Parvez ., et al. Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ. Health Perspect. 112 (2004) 1329-1333
36. Watanabe C., Inaoka T., Matsui T., Ishigaki K., Murayama N., and Ohtsuka R. Effects of arsenic on younger generations. J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng. 38 (2003) 129-139
37. Wei M., Wanibuchi H., Morimura K., et al. Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors. Carcinogenesis 23 (2002) 1387-1397
38. Yamanaka K., Katsumata K., Ikuma K., Hasegawa A., Nakano M., and Okada S. The role of orally administered dimethylarsinic acid, a main metabolite of inorganic arsenics, in the promotion and progression of UVB-induced skin tumorigenesis in hairless mice. Cancer Lett. 152 (2000) 79-85
39. Yamanaka K., Mizol M., Kato K., Hasegawa A., Nakano M., and Okada S. Oral administration of dimethylarsinic acid, a main metabolite of inorganic arsenic, in mice promotes skin tumorigenesis initiated by dimethylbenz(a)anthracene with or without ultraviolet B as a promoter. Biol. Pharm. Bull. 24 (2001) 510-514
40. Yamauchi H., and Yamamura Y. Metabolism and excretion of orally administered dimethylarsinic acid in the hamster. Toxicol. Appl. Pharmacol. 174 (1984) 134-140