Biochemical changes in brain and other tissues of young adult female mice from fluoride in their drinking water

Fluoride

Volumn 39, Issue 4, 2006, Pages 280-284

  Bhatnagar, M ^a,b   Rao, P ^a   Saxena, A ^a   Bhatnagar, R ^a,c   Meena, P ^a   Barbar, S ^a   Chouhan, A ^a   Vimal, S ^a  

^a Mohan Lal Sukhadia ^*

^b RNT MEDICAL COLLEGE   (India)

^c M L SUKHADIA UNIVERSITY   (India)

Author keywords

Acetylcholinesterase; Ascorbic acid; Catalase; Cholinesterase; Female mice; Liver; Malondialdehyde; Mouse brain; Muscles; Superoxide dismutase

Indexed keywords

ACETYLCHOLINESTERASE; ASCORBIC ACID; CATALASE; CHOLINESTERASE; DRINKING WATER; FLUORIDE SODIUM; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL COMPOSITION; BRAIN TISSUE; CONTROLLED STUDY; FEMALE; GASTROCNEMIUS MUSCLE; LIPID PEROXIDATION; MOUSE; NONHUMAN; WATER ANALYSIS;

MAMMALIA; MUS;

EID: 33846605161     PISSN: 00154725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Spittle B. Psychopharmacology of fluoride: a review. Clin Psychopharmacol 1994;9:79-82.
2. Singh KB, Dominic CJ. Sodium fluoride induced changes in the hypothalamic neurosecretory system of the spotted owlet (Alhene brama temminick). Endocrinol Exp 1975;9:149-55.
3. Mullenix PJ, Denbesten PK, Schunior A, Kernan WJ. Neurotoxicity of sodium fluoride in rats. Neurotoxicol Teratol 1995;17:169-77.
4. Varner JA, Huie C, Horvath W, Jenson KF, Issacson RL. Chronic AIF3 administration: II selected histological observations. Neurosci Res Commun 1993;13:99-104.
5. Varner JA, Jensen KF, Horvath W, Issacon RL. Chronic administration of aluminium fluoride or sodium fluoride to rats in drinking water: Alterations in neuronal and cerebrovascular integrity. Brain Res 1998;784:284-98.
6. Lu X-H, Li G-S, Sun B. Study of the mechanism of neurone apoptosis in rats from chronic fluorosis. Chinese J Epidem 2000;19:96-108.
7. Vani LM, Reddy PK. Effect of fluoride accumulation on some enzymes of brain and gastrocnemius muscles of mice. Fluoride 2000;33:17-26.
8. Shivarajashankara YM, Shivashankara AR, Bhat GP, Rao SM, Rao SH. Histological changes in rat brain of young fluoride intoxicated rats. Fluoride 2002;35:12-21.
9. Ge Y, Ning H, Wang S, Wang J. Effects of high fluoride and low iodine on brain effects of high fluoride and low iodine on brain histopathology in offspring rats. Fluoride 2005;38:127-32.
10. Ge Y, Ning W, Wang S, Wang J. Comet assay of DNA damage in brain cells of adult rats exposed to high fluoride and low iodine. Fluoride 2005;38:209-14.
11. Tsunoda M, Aizawa Y, Nakana K, Liu Y, Horuchi T, Hai K, Tsunoda H. Changes in fluoride levels in the liver, kidney and brain and in neurotransmitters of mice after subacute administration of fluoride. Fluoride 2005;38:284-92.
12. Inkielewicz I, Rogowaska M, Krechniak J. Lipid peroxidation and antioxidant enzyme activity in rats exposed to fluoride and ethanol. Fluoride 2006;39:53-9.
13. Byers DM, Irwin LN, Moss DE, Somaya IC, Hohmann CF. Prenatal exposure to acetylcholinesterase inhibitor methanosulfonyl fluoride alters forebrain morphology and gene expression. Brain Res Dev Brain Res 2005;158:13-22.
14. Blaylock RL. Excitotoxicity: a possible central mechanism in fluoride neurotoxicity. Fluoride 2004;37:301-14.
15. Chlubeck D, Nowacki P, Mikolajek W, Lagoska R, Jakubowaska K, Rzeuski R. Neurotoxicity of fluoride in rats-neuropathological studies. Fluoride, 1998;31:324.
16. Monsour PA, Kruger BJ. Effect of fluoride on soft tissue in vertebrates (A Review). Fluoride 1985;18:53-61.
17. Chinoy NJ, Nair SB, Zhala DD. Arsenic and fluoride induced toxicity in gastrocnemius muscle of mice and its reversal by therapeutic agents. Fluoride 2004;37:243-8.
18. Shuangxiu W, Zhang J, Wang J. Effects of high fluoride on sperm quality and testicular histology in male rats. Fluoride 2006;39:17-21.
19. Ge Y, Ning H, Wang S, Wang J. DNA damage in thyroid gland cells of rats exposed to long term intake of high fluoride and low iodide. Fluoride 2005;38:318-23.
20. Patel D, Chinoy NJ. Influence of fluoride on biological free radical reactions in ovary of mice and its reversal. Fluoride 1998;31:S27.
21. Bhatnagar M, Rao P, Shukla S, Jain S. Neurotoxicity of fluoride: evidence of neurodegeneration in hippocampus of female mice. Ind J Exp Biol 2002;40:546-54.
22. Bhatnagar M, Rao P, Bhatnagar C, Bhatnagar R. Trace element concentration in various tissues following fluoride administration to female mice. Ind J Exp Biol 2003;41:652-4.
23. Chinoy NJ, Patel TN. The influence of fluoride and/or aluminium on free radical toxicity in the brain of female mice and beneficial effects of some antidotes. Fluoride 2000;33:S8.
24. Shanthakumari D, Srinivalasalu S, Subramanian S. Effect of fluoride intoxication on lipid peroxidation and antioxidant status in experimental rats. Toxicology 2004;204:219-28.
25. Shivrajashankra YM, Shivashankra AR, Bhat GP, Rao SH. Brain lipid peroxidation and antioxidant systems of young rats in chronic fluoride intoxication. Fluoride 2002;35:197-203.
26. Sun G, Qui L, Ding G, Qian C, Zheng Q. Effect of carotene and SOD on lipid peroxidation and antioxidation of the offsprings of rats. Zhonghua Yu Fang Yi Xue Za Zhi 2000;34:134-5. [in Chinese].
27. Shivarajashankara YM, Shivashankara AR, Bhat GP, Rao SH. Effect of fluoride intoxication on lipid peroxidation and antioxidant systems in rats. Fluoride 2001;34:108-13.
28. Shao Q, Wang Y, Guan Z. Influence of free radical inducer on the level of oxidative stress in brain of rats with fluorosis. Zhonghua Yu Fang Yi Xue Za Zhi 2000;34:330-2. [in Chinese].
29. Wang JD, Ge YM, Ning HM, Wang SL. Effect of high fluoride and low iodine on oxidative stress and antioxidant defense of the brain in offspring rats. Fluoride 2004;37:264-70.
30. Zhang Z, Xu X, Shen X, Xu X. Effect of fluoride exposure on synaptic structure of brain areas related to learning-memory in mice. Wei Sheng Yan Jiu 1999;28:210-12. [in Chinese].
31. Zhang Z, Shen X, Xu-X. Effects of selenium on the damage of learning -memory ability of mice induced by fluoride. Wei Sheng Yan Jiu 2001;30:144-6. [in Chinese]
32. Malin DH, Plotner RE, Radulescu SJ, Ferebee RN, Lake JR, Negrete PG, Schaefer PJ, Crothers MK, Moss D. Chronic methyl sulfonyl fluoride enhances one trial per day reward learning in aged rats. Neurobiol Ageing 1993;14:393-5.
33. Wang JD, Ge YM, Ning HM, Wang SL. Effects of high fluoride and low iodine on biochemical indexes of the brain and learning-memory of offspring rats. Fluoride 2004;37:201-8.
34. Susheela AK. A treatise on fluorosis. Delhi: Fluorosis Research and Rural Development Foundation; 2001.
35. Ellman GL, Courney UD, Andres Junior V, Featherstone RM. A new and rapid colorimetric determination of AchE activity. Biochem Pharmacol 1961;7:88-95.
36. Winterbourn CC, Hawkins RE, Brain M, Charrell RW. The estimation of red cell superoxide dismutase activity. J Lab Clin Med 1974;85:337-41.
37. Sinha AK. Colorimetric assay of Catalase. Annl Biochem 1972;47:389-90.
38. Netelson S. Techniques of clinical chemistry, 3rd ed. Springfield, IL: Charles C Thomas;1971.
39. Buege JA, Aust SD. The thiobarbituric acid assay. Methods of enzymol 1978;52:306-7.
40. Lowry OH, Rosenbrough N, Randal RJ. Protein measurement with Folin phenol reagent. J Biol Chem 1951;193:265-75.
41. Zhao X, Wa JH. Actions of sodium fluoride on acetylcholinesterase activities in rats. Biomed Env Sci 1998;11:1-6.
42. Zhai JX, Guo ZY, Hu CL, Wang QN, Zhu QX. Studies on fluoride concentration and cholinesterase activity in rat hippocampus. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2003;21:102-4. [in Chinese].
43. Sun Z-R, Liu F-Z, Wu L-N et al. Effects of high fluoride drinking water on the cerebral functions of mice. Chin J of Epidem 2000;19:262-3.
44. Chandalia A. A study on fluoride toxicity before and after intervention. PhD dissertation submitted to MLS University, Udaipur, India; 2004.
45. Xun YL, Lu CHSH, Zhan XN. The effect of fluoride on intelligence quotient of children. Endem Dis Bull 1994;9:83-4. [in Chinese].
46. Hong FG, Cao YX, Yang D, Wang H. The effect of fluoride on intelligence of children exposed to different environments. Chin Prim Health Care 2001;15:56-7. [in Chinese].
47. Shashi A, Singh JP, Thaper SP. Effect of long-term administration of fluoride on levels of protein free amino acids and RNA in rabbit brain. Fluoride 1994;27:155-9.