Decreased nitric oxide markers and morphological changes in the brain of arsenic-exposed rats

Toxicology

Volumn 261, Issue 1-2, 2009, Pages 68-75

  Rios R ^a   Zarazua S ^a   Santoyo, M E ^a   Sepulveda Saavedra J ^b   Romero Diaz V ^b   Jimenez V ^a   Perez Severiano F ^c   Vidal Cantu G ^d   Delgado, J M ^a   Jimenez Capdeville M E ^a  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

^c NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^d DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Arsenic neurotoxicity; Nitric oxide; Nitric oxide synthase

Indexed keywords

ARSENIC; DRINKING WATER; KAINIC ACID; LIPID PEROXIDASE; MARKER; MESSENGER RNA; NEURONAL NITRIC OXIDE SYNTHASE; NITRATE; NITRIC OXIDE; NITRITE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN TISSUE; CELL SHAPE; CELL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROL GROUP; CONTROLLED STUDY; CORPUS STRIATUM; DEVELOPMENTAL STAGE; FEMALE; IMMUNOREACTIVITY; LACTATION; LIPID PEROXIDATION; MALE; MICROSCOPY; NERVE CELL; NERVE CELL LESION; NERVE FIBER; NERVE TRACT; NONHUMAN; OXIDATIVE STRESS; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; TISSUE INJURY; WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 66049164410     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.04.055     Document Type: Article

References (57)

1. Ali S.F., LeBel C.P., and Bondy S.C. Reactive oxygen species formation as a biomarker of methylmercury and trimethylin neurotoxicity. Neurotoxicology 13 (1992) 637-648
2. Bancroft J.D., and Stevens A. Theory and Practice of Histological Techniques. 2nd ed. (1982), Churchill Livingstone, Edinburgh/London/Melbourne/New York pp. 109-114, 217-223
3. Bliss T.V.P., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
4. Bredt D.S., Glatt C.E., Hwang P.M., Fotuhi M., Dawson T.M., and Snyder S.H. Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron 7 4 (1991) 615-624
5. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52 (1978) 302-310
6. Calderón J., Navarro M.E., Jimenez-Capdeville M.E., Santos-Diaz M.A., Golden A., Rodriguez-Leyva I., Borja-Aburto V., and Díaz-Barriga F. Exposure to arsenic and lead and neuropsychological development in Mexican children. Environ. Res. 85 (2001) 69-76
7. Chattopadhyay S., Ghosh S., Chaki S., Debnath J., and Ghosh D. Effect of sodium arsenite on plasma levels of gonadotrophins and ovarian steroidogenesis in mature albino rats: duration-dependent response. J. Toxicol. Sci. 24 (1999) 425-431
8. Chen C.J., Hsu L.I., Wang C.H., Shih W.L., Hsu Y.H., Tseng M.P., Lin Y.C., Chou W.L., Chen C.Y., Lee C.Y., Wang L.H., Cheng Y.C., Chen C.L., Chen S.Y., Wang Y.H., Hsueh Y.M., Chiou H.Y., and Wu M.M. Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan. Toxicol. Appl. Pharmacol. 206 (2005) 198-206
9. Concha G., Vogler G., Lezcano D., Nermell B., and Vahter M. Exposure to inorganic arsenic metabolites during early human development. Toxicol. Sci. 44 (1998) 185-190
10. Dakeishi M., Murata K., and Grandjean P. Long-term consequences of arsenic poisoning during infancy due to contaminated milk powder. Environ. Health 5 (2006) 31-37
11. Dhar P., Mohari N., and Mehra R. Preliminary morphological and morphometric study of rat cerebellum following sodium arsenite exposure during rapid brain growth (RBG) period. Toxicology 234 (2007) 10-20
12. Diaz-Barriga F., Hernandez J.M., Carrizales L., Dominguez M.C., Yañez L., Palmer E., and Saborio J.L. Interactions of cadmium with actin microfilaments. Toxicol. In Vitro 3 (1989) 277-284
13. Edelman G.M., and Gally J.A. Nitric oxide: linking space and time in the brain. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 11651-11652
14. Engel R.R., Hopenhayn-Rich C., Receveur O., and Smith A.H. Vascular effects of chronic arsenic exposure: a review. Epidemiol. Rev. 16 (1994) 184-209
15. Flora S.J., Bhadauria S., Pant S.C., and Dhaked R.K. Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats. Life Sci. 77 (2005) 2324-2337
16. Gally J.A., Montague P.R., Reeke G.N., and Edelman G.M. The NO hypothesis: possible effects of a short-lived, rapidly diffusible signal in the development and function of the nervous system. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 3547-3555
17. García-Chávez E., Segura B., Merchant H., Jiménez I., and Del Razo L.M. Functional and morphological effects of repeated sodium arsenite exposure in rat peripheral sensory nerves. J. Neurol. Sci. 258 (2007) 104-110
18. Gonzalez-Barrios J.A., Escalante B., Valdés J., León-Chávez B.A., and Martínez-Fong D. Nitric oxide and nitric oxide synthases in the fetal cerebral cortex of rats following transient uteroplacental ischemia. Brain Res. 945 (2002) 114-122
19. Gridley M.F. Manual of Histology and Special Staining Techniques. 2nd ed. (1960), McGraw Hill, New York
20. Hsieh F.I., Hwang T.S., Hsieh Y.C., Lo H.C., Su C.T., Hsu H.S., Chiou H.Y., and Chen C.J. Risk of erectile dysfunction induced by arsenic exposure through well water consumption in Taiwan. Environ. Health Perspect. 116 (2008) 532-536
21. Hughes M. Arsenic toxicity and potential mechanism of action. Toxicol. Lett. 133 (2002) 1-16
22. Jin Y., Sun G., Li X., Chunwei L., and Qu L. Study on the toxic effects induced by different arsenicals in primary culture rat astroglia. Toxicol. Appl. Pharmacol. 196 (2004) 396-403
23. Kamada Y., Jenkins G.J., Lau M., Dunbar A.Y., Lowe E.R., and Osawa Y. Tetrahydrobiopterin depletion and ubiquitylation of neuronal nitric oxide synthase. Brain Res. Mol. Brain Res. 142 (2005) 19-27
24. Klüver H., and Barrera E. A method for the combined staining of cells and fibers in the nervous system. J. Neuropathol. Exp. Neurol. 12 (1953) 400-403
25. Krüger K., Repges H., Hippler J., Hartmann L.M., Hirner A.V., Straub H., Binding N., and Mußhoff U. Effects of dimethylarsinic and dimethylarsinous acid on evoked synaptic potentials in hippocampal slices of young and adults rats. Toxicol. Appl. Pharmacol. 225 (2007) 40-46
26. Lee C., Surtees R., and Duchen L.W. Distal motor axonopathy and central nervous system myelin vacuolation caused by cycloleucine, and inhibitor of methionine adenosyltransferase. Brain 115 (1992) 935-955
27. Lee M.Y., Jung B.I., Chung S.M., Bae O.N., Lee J.Y., Park J.D., Yang J.S., Lee H., and Chung J.H. Environ. Health Perspect. 111 4 (2003) 513-517
28. Likert R. A technique for the measurement of attitudes. Arch. Psychol. 140 (1932) 1-55
29. Lowry O.H., Rosenbrough N.J., Farr L., and Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
30. Mittal M., and Flora S.J.S. Effects of individual and combined exposure to sodium arsenite and sodium fluoride on tissue oxidative stress, arsenic and fluoride levels in male mice. Chem. Biol. Interact. 162 2 (2006) 128-139
31. Mallory F.B. Pathology Techniques (1961), Hafner Publishing, New York pp. 158-180
32. Miranda K.M., Espey M.G., and Wink D.A. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide: Biol. Chem. 5 (2001) 62-71
33. National Research Council of the National Academies. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research (2003), The National Academies Press, Washington, DC
34. Nott A., Watson P.M., Robinson J.D., Crepaldi L., and Riccio A. S-nitrosylation of histone deacetylase 2 induces chromatin remodeling in neurons. Nature 455 (2008) 411-415
35. Paxinos G., and Watson C. The Rat Brain Stereotaxic Coordinates (2004), Academic Press, New York
36. Perez-Severiano F., Escalante B., Vergara P., Ríos C., and Segovia J. Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation. Brain Res. 951 (2002) 36-42
37. Pérez-Severiano F., Santamaría A., Pedraza-Chaverri J., Medina-Campos O.N., Ríos C., and Segovia J. Increased formation of reactive oxygen species, but no changes in glutathione peroxidase activity, in striata of mice transgenic for the Huntington's disease mutation. Neurochem. Res. 29 (2004) 729-733
38. Piao F.N., Hiraku Y., Murata M., Oikawa S., Cheng F., Zhong L., Yamauchi T., Kawanishi S., and Yokoyama K. Oxidative DNA damage in relation to neurotoxicity in the brain of mice exposed to arsenic at environmentally relevant levels. J. Occup. Health 47 (2005) 445-449
39. Pi J., Horiguchi S., Sun Y., Nikaido M., Shimojo N., Hayashi T., Yamauchi H., Itoh K., Yamamoto M., Sun G., Waalkes M.P., and Kumagai Y. A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits. Free Radic. Biol. Med. 35 (2003) 102-113
40. Pi J., Kumagai Y., Sun G., Yamauchi H., Yoshida T., Iso H., Endo A., Yu L., Yuki K., Miyauchi T., and Shimojo N. Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia. Free Radic. Biol. Med. 28 (2000) 1137-1142
41. Pi J., Yamauchi H., Kumagai Y., Sun G., Yoshida T., Aikawa H., Hopenhayn-Rich C., and Shimojo N. Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water. Environ. Health Perspect. 110 (2002) 331-336
42. Ramirez T., Stopper H., Fisher T., Hock R., and Herrera L.A. S-adenosyl l-methionine counteracts mitotic disturbances and cytostatic effects induced by sodium arsenite in HeLa cells. Mutat. Res. 637 (2008) 152-160
43. Richardson K.C., Jarret E.H., and Finke E.H. Embedding in epoxic resins for ultrathin sectioning in electron microscopy. Stain Technol. 35 (1960) 313-323
44. Rodríguez V.M., Carrizales L., Jiménez-Capdeville M.E., Dufour L., and Giordano M. The effects of sodium arsenite exposure on behavioral parameters in the rat. Brain Res. Bull. 55 (2001) 301-308
45. Rosado J.L., Ronquillo D., Kordas K., Rojas O., Alatorre J., Lopez P., Garcia-Vargas G., Del Carmen Caamaño M., Cebrián M.E., and Stoltzfus R.J. Arsenic exposure and cognitive performance in Mexican schoolchildren. Environ. Health Perspect. 115 (2007) 1371-1375
46. Santoyo M.E., Sepúlveda-Saavedra J., Zarazúa S., Pérez-Severiano F., Romero-Díaz V., Ceballos F., Juárez B., and Jiménez-Capdeville M.E. Neurochemical and morphological alterations in the rat brain associated with chronic arsenic exposure. In: Santamaría A., and Jiménez-Capdeville M.E. (Eds). New Perspectives on Brain Damage, Neurodegeneration and Neuroprotective Strategies (2007), Research Signpost, Kerala, India pp. 189-201
47. Shi H., Shi X., and Liu K.J. Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol. Cell. Biochem. 255 (2004) 67-78
48. Shila S., Kokilavani V., Subathara M., and Panneerselvam C. Brain regional responses in antioxidant system to α-lipoic acid in arsenic intoxicated rat. Toxicology 210 (2005) 25-36
49. Sumi D., Taguchi K., Sun Y., Shinkai Y., and Kumagai Y. Monomethylarsonous acid inhibits endothelial nitric oxide synthase activity. J. Health Sci. 51 (2005) 728-730
50. Tsou T.C., Tsai F.Y., Hsieh Y.W., Li L.A., Yeh S.C., and Chang L.W. Arsenite induces endothelial cytotoxicity by down-regulation of vascular endothelial nitric oxide synthase. Toxicol. Appl. Pharmacol. 208 (2005) 277-284
51. Vahidnia A., Romijn F., van der Voet G.B., and de Wolff F.A. Arsenic-induced neurotoxicity in relation to toxicokinetics: effects on sciatic nerve proteins. Chem. Biol. Interact. 176 (2008) 188-195
52. Vahidnia A., Romijn F., Tiller M., van der Voet G.B., and de Wolff F.A. Arsenic-induced toxicity: effect on protein composition in sciatic nerve. Hum. Exp. Toxicol. 25 (2006) 667-674
53. Vahter M. Health effects of early life exposure to arsenic. Basic Clin. Pharmacol. Toxicol. 102 (2007) 204-211
54. Wasserman G.A., Liu X., Parvez F., Ahsan H., Factor-Litvak P., van Geen A., Slavkovich V., LoIacono N.J., Cheng Z., Hussain I., Momotaj H., and Graziano J.H. Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ. Health Perspect. 112 (2004) 1329-1333
55. Wasserman G.A., Liu X., Parvez F., Ahsan H., Factor-Litvak P., Kline J., Van Geen A., Slavkovich V., Lolacono N.J., Levy D., Cheng Z., and Graziano J.H. Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh. Environ. Health Perspect. 115 (2007) 285-289
56. Yang H.T., Chou H.J., Han B.C., and Huang S.Y. Lifelong inorganic arsenic compounds consumption affected blood pressure in rats. Food Chem. Toxicol. 45 (2007) 2479-2487
57. Zarazua S., Perez-Severiano F., Delgado J.M., Martínez L.M., Ortiz-Perez D., and Jimenez-Capdeville M.E. Decreased nitric oxide production in the rat brain alter chronic arsenic exposure. Neurochem. Res. 31 (2006) 1069-1077