Impact of cigarette smoke on the human and mouse lungs: A gene-expression comparison study

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Morissette, Mathieu C ^a   Lamontagne, Maxime ^b   Bérubé, Jean Christophe ^b   Gaschler, Gordon ^a   Williams, Andrew ^e   Yauk, Carole ^e   Couture, Christian ^b   Laviolette, Michel ^b   Hogg, James C ^c   Timens, Wim ^d   Halappanavar, Sabina ^e   Stampfli, Martin R ^a,f   Bossé, Yohan ^b,g  

^a MCMASTER UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^e HEALTH CANADA   (Canada)

^f MCMASTER UNIVERSITY   (Canada)

^g UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; CYTOCHROME P450 1B1; GLUTATHIONE TRANSFERASE A2; GROWTH DIFFERENTIATION FACTOR 15; MACROPHAGE ELASTASE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; OSTEOPONTIN; PHOSPHOLIPID; SMOKE; TRANSCRIPTOME;

ACP5 GENE; ADULT; AHRR GENE; ALDH3A1 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATP6V0D2 GENE; BHLHE41 GENE; BIOLOGICAL FUNCTIONS; CLEC5A GENE; COMPARATIVE STUDY; CONTROLLED STUDY; CYP1B1 GENE; FEMALE; GDF15 GENE; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC ASSOCIATION; GSTA2 GENE; HEALTH IMPACT ASSESSMENT; HUMAN; HUMAN TISSUE; LCN2 GENE; LIPID DEGRADATION; LUNG; LUNG CANCER; MALE; MMP12 GENE; MOUSE; NEK6 GENE; NONHUMAN; NQO1 GENE; NUCLEOTIDE SEQUENCE; PHOSPHOLIPID METABOLISM; PLA2G7 GENE; SIGNAL TRANSDUCTION; SMOKING; SPP1 GENE; TM7SF4 GENE; TREM2 GENE; ANIMAL; DRUG EFFECTS; METABOLISM; MIDDLE AGED; SMOKE; SPECIES DIFFERENCE; TOBACCO;

ANIMALS; FEMALE; HUMANS; LUNG; MALE; MICE; MIDDLE AGED; PHOSPHOLIPIDS; SMOKE; SPECIES SPECIFICITY; TOBACCO PRODUCTS; TRANSCRIPTOME;

EID: 84899737699     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092498     Document Type: Article

References (46)

1. Jha P (2009) Avoidable global cancer deaths and total deaths from smoking. Nat Rev Cancer 9: 655-664.
2. Churg A, Sin DD, Wright JL (2011) Everything Prevents Emphysema: Are Animal Models of Cigarette Smoke-Induced COPD Any Use? Am J Respir Cell Mol Biol.
3. Bosse Y, Postma DS, Sin DD, Lamontagne M, Couture C et al. (2012) Molecular signature of smoking in human lung tissues. Cancer Res 72: 3753-3763.
4. Botelho FM, Gaschler GJ, Kianpour S, Zavitz CC, Trimble NJ et al. (2010) Innate immune processes are sufficient for driving cigarette smoke-induced inflammation in mice. Am J Respir Cell Mol Biol 42: 394-403.
5. Gaschler GJ, Zavitz CC, Bauer CM, Stampfli MR (2010) Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lungs1. Eur Respir J.
6. Bauer CM, Zavitz CC, Botelho FM, Lambert KN, Brown EG, et al. (2010) Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection. PLoS One 5: e13251.
7. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-15550. (Pubitemid 41528093)
8. Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, et al. (2009) Lineage-specific biology revealed by a finished genome assembly of the mouse. PLoS Biol 7: e1000112.
9. Churg A, Wang RD, Tai H, Wang X, Xie C, et al. (2003) Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. Am J Respir Crit Care Med 167: 1083-1089. (Pubitemid 36459653)
10. Lagente V, Le Quement C, Boichot E (2009) Macrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases. Expert Opin Ther Targets 13: 287-295.
11. Shan M, Yuan X, Song LZ, Roberts L, Zarinkamar N, et al. (2012) Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema. Sci Transl Med 4: 117ra9.
12. Thatcher TH, Maggirwar SB, Baglole CJ, Lakatos HF, Gasiewicz TA, et al. (2007) Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB. Am J Pathol 170: 855-864. (Pubitemid 47339355)
13. Rico de Souza A, Zago M, Pollock SJ, Sime PJ, Phipps RP, et al. (2011) Genetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosis. J Biol Chem 286: 43214-43228.
14. Agundez JA (2004) Cytochrome P450 gene polymorphism and cancer. Curr Drug Metab 5: 211-224.
15. Zhang H, Forman HJ (2009) Signaling pathways involved in phase II gene induction by alpha, beta-unsaturated aldehydes. Toxicol Ind Health 25: 269-278.
16. Bakker AB, Baker E, Sutherland GR, Phillips JH, Lanier LL (1999) Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. Proc Natl Acad Sci U S A 96: 9792-9796. (Pubitemid 29398811)
17. Sharif O, Knapp S (2008) From expression to signaling: roles of TREM-1 and TREM-2 in innate immunity and bacterial infection. Immunobiology 213: 701-713.
18. Hayes JD, Flanagan JU, Jowsey IR (2005) Glutathione transferases. Annu Rev Pharmacol Toxicol 45: 51-88. (Pubitemid 40261798)
19. Strelau J, Bottner M, Lingor P, Suter-Crazzolara C, Galter D, et al. (2000) GDF-15/MIC-1 a novel member of the TGF-beta superfamily. J Neural Transm Suppl 273-276. (Pubitemid 32037199)
20. Fairlie WD, Moore AG, Bauskin AR, Russell PK, Zhang HP, et al. (1999) MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation. J Leukoc Biol 65: 2-5. (Pubitemid 29024911)
21. Khaled YS, Elkord E, Ammori BJ (2012) Macrophage inhibitory cytokine-1: a review of its pleiotropic actions in cancer. Cancer Biomark 11: 183-190.
22. de Jager SC, Bermudez B, Bot I, Koenen RR, Bot M, et al. (2011) Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. J Exp Med 208: 217-225.
23. Hochholzer W, Morrow DA, Giugliano RP (2010) Novel biomarkers in cardiovascular disease: update 2010. Am Heart J 160: 583-594.
24. Tsai VW, Macia L, Johnen H, Kuffner T, Manadhar R, et al. (2013) TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One 8: e55174.
25. Wu Q, Jiang D, Chu HW (2012) Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: implication in mucin overexpression. Innate Immun 18: 617-626.
26. Arai H, Koizumi H, Aoki J, Inoue K (2002) Platelet-activating factor acetylhydrolase (PAF-AH). J Biochem 131: 635-640. (Pubitemid 34535029)
27. Toth PP, McCullough PA, Wegner MS, Colley KJ (2010) Lipoprotein- associated phospholipase A2: role in atherosclerosis and utility as a cardiovascular biomarker. Expert Rev Cardiovasc Ther 8: 425-438.
28. Singh U, Zhong S, Xiong M, Li TB, Sniderman A, et al. (2004) Increased plasma non-esterified fatty acids and platelet-activating factor acetylhydrolase are associated with susceptibility to atherosclerosis in mice. Clin Sci (Lond) 106: 421-432. (Pubitemid 38559066)
29. Imaizumi T, Satoh K, Yoshida H, Kawamura Y, Hiramoto M, et al. (1990) Activity of platelet-activating factor (PAF) acetylhydrolase in plasma from healthy habitual cigarette smokers. Heart Vessels 5: 81-86. (Pubitemid 20212058)
30. Yamada K, Miyamoto K (2005) Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli. Front Biosci 10: 3151-3171. (Pubitemid 40910554)
31. Fry AM, O'Regan L, Sabir SR, Bayliss R (2012) Cell cycle regulation by the NEK family of protein kinases. J Cell Sci 125: 4423-4433.
32. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, et al. (2007) Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol 18: 407-413. (Pubitemid 46193306)
33. Wu H, Xu G, Li YP (2009) Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption. J Bone Miner Res 24: 871-885.
34. Kim T, Ha HI, Kim N, Yi O, Lee SH, et al. (2009) Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation. Biochem Biophys Res Commun 390: 585-590.
35. Lee SH, Rho J, Jeong D, Sul JY, Kim T, et al. (2006) v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med 12: 1403-1409. (Pubitemid 44924499)
36. Kim T, Ha H, Kim N, Park ES, Rho J, et al. (2010) ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss. Biochem Biophys Res Commun 403: 73-78.
37. Hayman AR (2008) Tartrate-resistant acid phosphatase (TRAP) and the osteoclast/immune cell dichotomy. Autoimmunity 41: 218-223.
38. Suter A, Everts V, Boyde A, Jones SJ, Lullmann-Rauch R, et al. (2001) Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice. Development 128: 4899-4910. (Pubitemid 33138599)
39. Yagi M, Miyamoto T, Sawatani Y, Iwamoto K, Hosogane N, et al. (2005) DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med 202: 345-351. (Pubitemid 41126951)
40. Korashy HM, El-Kadi AO (2006) The role of aryl hydrocarbon receptor in the pathogenesis of cardiovascular diseases. Drug Metab Rev 38: 411-450.
41. Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, et al. (2002) Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 21: 7435-7451. (Pubitemid 35305599)
42. Esser C, Rannug A, Stockinger B (2009) The aryl hydrocarbon receptor in immunity. Trends Immunol 30: 447-454.
43. Church DF, Pryor WA (1985) Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 64: 111-126. (Pubitemid 16135783)
44. Wymann MP, Schneiter R (2008) Lipid signalling in disease. Nat Rev Mol Cell Biol 9: 162-176. (Pubitemid 351158917)
45. Rahman I, van Schadewijk AA, Crowther AJ, Hiemstra PS, Stolk J, et al. (2002) 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 166: 490-495.
46. Thimmulappa RK, Gang X, Kim JH, Sussan TE, Witztum JL, et al. (2012) Oxidized phospholipids impair pulmonary antibacterial defenses: evidence in mice exposed to cigarette smoke. Biochem Biophys Res Commun 426: 253-259.