Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lungs

European Respiratory Journal

Volumn 36, Issue 5, 2010, Pages 1131-1142

  Gaschler, G J ^a   Zavitz, C C J ^a   Bauer, C M T ^a   Stampfli M R ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Bacteria; Chronic obstructive pulmonary disease; Cigarette smoke; Exacerbation; Inflammation; Mice

Indexed keywords

CIGARETTE SMOKE; IMMUNOGLOBULIN A;

AMBIENT AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CELL FREE SYSTEM; CELL HYPERPLASIA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; GOBLET CELL; HAEMOPHILUS INFECTION; HAEMOPHILUS INFLUENZAE; LUNG CLEARANCE; LUNG LAVAGE; MOUSE; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, BACTERIAL; B-LYMPHOCYTES; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; GOBLET CELLS; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; LUNG; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUCUS; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING;

EID: 78349300621     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00113909     Document Type: Article

References (42)

1. Barnes PJ. Chronic obstructive pulmonary disease: a growing but neglected global epidemic. PLoS Med 2007; 4: e112.
2. Murray CJ, Lopez AD. Evidence-based health policy - lessons from the Global Burden of Disease Study. Science 1996; 274: 740-743.
3. Harber P, Tashkin DP, Simmons M, et al. Effect of occupational exposures on decline of lung function in early chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 176: 994-1000.
4. Eisner MD, Balmes J, Katz PP, et al. Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease. Environ Health 2005; 4: 7.
5. Barnes PJ. Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 2008; 8: 183-192.
6. Stämpfli MR, Anderson GP. How cigarette smoke skews immune responses to promote infection, lung disease and cancer. Nat Rev Immunol 2009; 9: 377-384.
7. Aaron SD, Angel JB, Lunau M, et al. Granulocyte inflammatory markers and airway infection during acute exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 163: 349-355.
8. Papi A, Bellettato CM, Braccioni F, et al. Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations. Am J Respir Crit Care Med 2006; 173: 1114-1121. (Pubitemid 43726892)
9. Wilkinson TM, Hurst JR, Perera WR, et al. Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD. Chest 2006; 129: 317-324.
10. Murphy TF, Brauer AL, Eschberger K, et al. Pseudomonas aeruginosa in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008; 177: 853-860.
11. Murphy TF, Brauer AL, Grant BJ, et al. Moraxella catarrhalis in chronic obstructive pulmonary disease: burden of disease and immune response. Am J Respir Crit Care Med 2005; 172: 195-199.
12. Sethi S, Evans N, Grant BJ, et al. New strains of bacteria and exacerbations of chronic obstructive pulmonary disease. N Engl J Med 2002; 347: 465-471. (Pubitemid 34879333)
13. Sethi S, Wrona C, Eschberger K, et al. Inflammatory profile of new bacterial strain exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008; 177: 491-497.
14. Sethi S, Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease. New Engl J Med 2008; 359: 2355-2365.
15. Gaschler GJ, Skrtic M, Zavitz CC, et al. Bacteria challenge in smoke exposed mice exacerbates inflammation and skews the inflammatory profile. Am J Respir Crit Care Med 2009; 179: 666-675.
16. Chen J, Trounstine M, Alt FW, et al. Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus. Int Immunol 1993; 5: 647-656.
17. Gaschler GJ, Zavitz CC, Bauer CM, et al. Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages. Am J Respir Cell Mol Biol 2008; 38: 218-226.
18. Fernaays MM, Lesse AJ, Cai X, et al. Characterization of igaB, a second immunoglobulin A1 protease gene in nontypeable Haemophilus influenzae. Infect Immun 2006; 74: 5860-5870.
19. Yi K, Sethi S, Murphy TF. Human immune response to nontypeable Haemophilus influenzae in chronic bronchitis. J Infect Dis 1997; 176: 1247-1252.
20. Sethi S, Muscarella K, Evans N, et al. Airway inflammation and etiology of acute exacerbations of chronic bronchitis. Chest 2000; 118: 1557-1565. (Pubitemid 32001777)
21. Stämpfli MR, Wiley RE, Neigh GS, et al. GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. J Clin Invest 1998; 102: 1704-1714.
22. Ellis R, Leigh R, Southam D, et al. Morphometric analysis of mouse airways after chronic allergen challenge. Lab Invest 2003; 83: 1285-1291.
23. Robbins CS, Bauer CM, Vujicic N, et al. Cigarette smoke impacts immune inflammatory responses to influenza in mice. Am J Respir Crit Care Med 2006; 174: 1342-1351.
24. Burge S, Wedzicha JA. COPD exacerbations: definitions and classifications. Eur Respir J 2003; 21: Suppl. 41, 46s-53s.
25. Stevenson CS, Coote K, Webster R, et al. Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect. Am J Physiol 2005; 288: L514-L522.
26. Johnson JR, Wiley RE, Fattouh R, et al. Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Respir Crit Care Med 2004; 169: 378-385. (Pubitemid 38134818)
27. Wright JL, Cosio M, Churg A. Animal models of chronic obstructive pulmonary disease. Am J Physiol 2008; 295: L1-L15.
28. Keatings VM, Collins PD, Scott DM, et al. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996; 153: 530-534.
29. Prescott E, Lange P, Vestbo J. Chronic mucus hypersecretion in COPD and death from pulmonary infection. Eur Respir J 1995; 8: 1333-1338.
30. Moghaddam SJ, Clement CG, De la Garza MM, et al. Haemophilus influenzae lysate induces aspects of the chronic obstructive pulmonary disease phenotype. Am J Respir Cell Mol Biol 2008; 38: 629-638.
31. Evans SE, Scott BL, Clement CG, et al. Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi. Am J Respir Cell Mol Biol 2010; 42: 40-50.
32. Atis S, Tutluoglu B, Salepci B, et al. Serum IgA and secretory IgA levels in bronchial lavages from patients with a variety of respiratory diseases. J Investig Allergol Clin Immunol 2001; 11: 112-117.
33. Stockley RA, Burnett D. Local IgA production in patients with chronic bronchitis: effect of acute respiratory infection. Thorax 1980; 35: 202-206.
34. Bennet KR, Reade PC. Salivary immunoglobulin A levels in normal subjects, tobacco smokers, and patients with minor aphthous ulceration. Oral Surg Oral Med Oral Pathol 1982; 53: 461-465.
35. Demoor T, Bracke KR, Maes T, et al. Role of lymphotoxin-α in cigarette smoke-induced inflammation and lymphoid neogenesis. Eur Respir J 2009; 34: 405-416.
36. Zola TA, Lysenko ES, Weiser JN. Natural antibody to conserved targets of Haemophilus influenzae limits colonization of the murine nasopharynx. Infect Immun 2009; 77: 3458-3465.
37. Lund FE, Schuer K, Hollifield M, et al. Clearance of Pneumocystis carinii in mice is dependent on B cells but not on P. carinii-specific antibody. J Immunol 2003; 171: 1423-1430.
38. Barnes PJ. Alveolar macrophages as orchestrators of COPD. COPD 2004; 1: 59-70.
39. Drannik AG, Pouladi MA, Robbins CS, et al. Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection. Am J Respir Crit Care Med 2004; 170: 1164-1171.
40. Rylander R. Lung clearance of particles and bacteria. Effects of cigarette smoke exposure. Arch Environ Health 1971; 23: 321-326.
41. Inoue S, Nakamura H, Otake K, et al. Impaired pulmonary inflammatory responses are a prominent feature of streptococcal pneumonia in mice with experimental emphysema. Am J Respir Crit Care Med 2003; 167: 764-770.
42. Tokairin Y, Shibata Y, Sata M, et al. Enhanced immediate inflammatory response to Streptococcus pneumoniae in the lungs of mice with pulmonary emphysema. Respirology 2008; 13: 324-332.