Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Khan, Younis M ^a   Kirkham, Paul ^b   Barnes, Peter J ^a   Adcock, Ian M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BROMODOMAIN CONTAINING PROTEIN 2; BROMODOMAIN CONTAINING PROTEIN 4; CHEMICAL COMPOUND; HOMEODOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; JQ1; PFI 1; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG; (+)-JQ1 COMPOUND; AZEPINE DERIVATIVE; BRD2 PROTEIN, HUMAN; BRD4 PROTEIN, HUMAN; HYDROGEN PEROXIDE; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR; TRIAZOLE DERIVATIVE;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTONE ACETYLATION; HUMAN; HUMAN CELL; INFLAMMATION; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM; RESPIRATORY EPITHELIUM CELL; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; EPITHELIUM CELL; IMMUNOLOGY; METABOLISM;

AZEPINES; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; TRIAZOLES;

EID: 84899725329     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095051     Document Type: Article

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