메뉴 건너뛰기




Volumn 183, Issue 1, 2009, Pages 411-420

Neutrophil elastase represses IL-8/CXCL8 synthesis in human airway smooth muscle cells through induction of NF-κB repressing factor

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LEUKOCYTE ELASTASE; MESSENGER RNA; NUCLEAR FACTOR KAPPA B REPRESSING FACTOR; RNA POLYMERASE II; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; NKRF PROTEIN, HUMAN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR RELA;

EID: 68949136953     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803729     Document Type: Article
Times cited : (26)

References (44)
  • 1
    • 0034109665 scopus 로고    scopus 로고
    • Airway smooth muscle cells: Contributing to and regulating airway mucosal inflammation?
    • Chung, K. F. 2000. Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation? Eur. Respir. J. 15: 961-968.
    • (2000) Eur. Respir. J. , vol.15 , pp. 961-968
    • Chung, K.F.1
  • 3
    • 0032168268 scopus 로고    scopus 로고
    • Bradykinin stimulates IL-8 production in cultured human airway smooth muscle cells: Role of cyclooxygenase products
    • Pang, L., and A. J. Knox. 1998. Bradykinin stimulates IL-8 production in cultured human airway smooth muscle cells: role of cyclooxygenase products. J. Immunol. 161: 2509-2515.
    • (1998) J. Immunol. , vol.161 , pp. 2509-2515
    • Pang, L.1    Knox, A.J.2
  • 5
    • 0031568394 scopus 로고    scopus 로고
    • Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: Regulation by T helper 2 cytokines and corticosteroids
    • John, M., S. J. Hirst, P. J. Jose, A. Robichaud, N. Berkman, C. Witt, C. H. Twort, P. J. Barnes, and K. F. Chung. 1997. Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: regulation by T helper 2 cytokines and corticosteroids. J. Immunol. 158: 1841-1847.
    • (1997) J. Immunol. , vol.158 , pp. 1841-1847
    • John, M.1    Hirst, S.J.2    Jose, P.J.3    Robichaud, A.4    Berkman, N.5    Witt, C.6    Twort, C.H.7    Barnes, P.J.8    Chung, K.F.9
  • 6
    • 0031039525 scopus 로고    scopus 로고
    • Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: Suppression by dexamethasone
    • Saunders, M. A., J. A. Mitchell, P. M. Seldon, M. H. Yacoub, P. J. Barnes, M. A. Giembycz, and M. G. Belvisi. 1997. Release of granulocyte- macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone. Br. J. Pharmacol. 120: 545-546.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 545-546
    • Saunders, M.A.1    Mitchell, J.A.2    Seldon, P.M.3    Yacoub, M.H.4    Barnes, P.J.5    Giembycz, M.A.6    Belvisi, M.G.7
  • 7
    • 53149123285 scopus 로고    scopus 로고
    • Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: Cooperative roles for CADM1, stem cell factor, and IL-6
    • Hollins, F., D. Kaur, W. Yang, G. Cruse, R. Saunders, A. Sutcliffe, P. Berger, A. Ito, C. E. Brightling, and P. Bradding. 2008. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J. Immunol. 181: 2772-2780.
    • (2008) J. Immunol. , vol.181 , pp. 2772-2780
    • Hollins, F.1    Kaur, D.2    Yang, W.3    Cruse, G.4    Saunders, R.5    Sutcliffe, A.6    Berger, P.7    Ito, A.8    Brightling, C.E.9    Bradding, P.10
  • 8
    • 0028917927 scopus 로고
    • Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion
    • Panettieri, R. A., Jr., A. L. Lazaar, E. Pure, and S. M. Albelda. 1995. Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion. J. Immunol. 154: 2358-2365.
    • (1995) J. Immunol. , vol.154 , pp. 2358-2365
    • Panettieri Jr., R.A.1    Lazaar, A.L.2    Pure, E.3    Albelda, S.M.4
  • 9
    • 0030927344 scopus 로고    scopus 로고
    • Effect of interleukin 1β, tumour necrosis factor α and interferon γ on the induction of cyclooxygenase-2 in cultured human airway smooth muscle cells
    • Pang, L., and A. J. Knox. 1997. Effect of interleukin 1β, tumour necrosis factor α and interferon γ on the induction of cyclooxygenase-2 in cultured human airway smooth muscle cells. Br. J. Pharmacol. 121: 579-587.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 579-587
    • Pang, L.1    Knox, A.J.2
  • 10
    • 0030843864 scopus 로고    scopus 로고
    • Synthetic functions of airway smooth muscle in asthma
    • Johnson, S. R., and A. J. Knox. 1997. Synthetic functions of airway smooth muscle in asthma. Trends Pharmacol. Sci. 18: 288-292.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 288-292
    • Johnson, S.R.1    Knox, A.J.2
  • 11
    • 34247500507 scopus 로고    scopus 로고
    • New molecular targets for the treatment of neutrophilic diseases
    • Barnes, P. J. 2007. New molecular targets for the treatment of neutrophilic diseases. J. Allergy Clin. Immunol. 119: 1055-1062.
    • (2007) J. Allergy Clin. Immunol. , vol.119 , pp. 1055-1062
    • Barnes, P.J.1
  • 12
    • 0031836105 scopus 로고    scopus 로고
    • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
    • Belaaouaj, A., R. McCarthy, M. Baumann, Z. Gao, T. J. Ley, S. N. Abraham, and S. D. Shapiro. 1998. Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat. Med. 4: 615-618.
    • (1998) Nat. Med. , vol.4 , pp. 615-618
    • Belaaouaj, A.1    McCarthy, R.2    Baumann, M.3    Gao, Z.4    Ley, T.J.5    Abraham, S.N.6    Shapiro, S.D.7
  • 13
    • 33748422072 scopus 로고    scopus 로고
    • Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-κB activation via EGFR transactivation in a lung epithelial cell line
    • Kuwahara, I., E. P. Lillehoj, W. Lu, I. S. Singh, Y. Isohama, T. Miyata, and K. C. Kim. 2006. Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-κB activation via EGFR transactivation in a lung epithelial cell line. Am. J. Physiol. 291: L407-L416.
    • (2006) Am. J. Physiol. , vol.291
    • Kuwahara, I.1    Lillehoj, E.P.2    Lu, W.3    Singh, I.S.4    Isohama, Y.5    Miyata, T.6    Kim, K.C.7
  • 14
    • 0035929634 scopus 로고    scopus 로고
    • Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium
    • Walsh, D. E., C. M. Greene, T. P. Carroll, C. C. Taggart, P. M. Gallagher, S. J. O'Neill, and N. G. McElvaney. 2001. Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium. J. Biol. Chem. 276: 35494-35499.
    • (2001) J. Biol. Chem. , vol.276 , pp. 35494-35499
    • Walsh, D.E.1    Greene, C.M.2    Carroll, T.P.3    Taggart, C.C.4    Gallagher, P.M.5    O'Neill, S.J.6    McElvaney, N.G.7
  • 16
    • 1542328799 scopus 로고    scopus 로고
    • Human neutrophil-derived elastase induces airway smooth muscle cell proliferation
    • Huang, C. D., H. H. Chen, C. H. Wang, C. L. Chou, S. M. Lin, H. C. Lin, and H. P. Kuo. 2004. Human neutrophil-derived elastase induces airway smooth muscle cell proliferation. Life Sci. 74: 2479-2492.
    • (2004) Life Sci. , vol.74 , pp. 2479-2492
    • Huang, C.D.1    Chen, H.H.2    Wang, C.H.3    Chou, C.L.4    Lin, S.M.5    Lin, H.C.6    Kuo, H.P.7
  • 18
    • 0026681802 scopus 로고
    • Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line
    • Nakamura, H., K. Yoshimura, N. G. McElvaney, and R. G. Crystal. 1992. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. J. Clin. Invest. 89: 1478-1484.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1478-1484
    • Nakamura, H.1    Yoshimura, K.2    McElvaney, N.G.3    Crystal, R.G.4
  • 19
    • 24744464353 scopus 로고    scopus 로고
    • Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-α-converting enzyme
    • Shao, M. X., and J. A. Nadel. 2005. Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-α-converting enzyme. J. Immunol. 175: 4009-4016.
    • (2005) J. Immunol. , vol.175 , pp. 4009-4016
    • Shao, M.X.1    Nadel, J.A.2
  • 20
    • 0942300674 scopus 로고    scopus 로고
    • Neutrophil elastase induces IL-8 synthesis by lung epithelial cells via the mitogen-activated protein kinase pathway
    • Chen, H. C., H. C. Lin, C. Y. Liu, C. H. Wang, T. Hwang, T. T. Huang, C. H. Lin, and H. P. Kuo. 2004. Neutrophil elastase induces IL-8 synthesis by lung epithelial cells via the mitogen-activated protein kinase pathway. J. Biomed. Sci. 11: 49-58.
    • (2004) J. Biomed. Sci. , vol.11 , pp. 49-58
    • Chen, H.C.1    Lin, H.C.2    Liu, C.Y.3    Wang, C.H.4    Hwang, T.5    Huang, T.T.6    Lin, C.H.7    Kuo, H.P.8
  • 22
    • 0026474443 scopus 로고
    • Modulation of airway inflammation in cystic fibrosis: In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor
    • McElvaney, N. G., H. Nakamura, P. Birrer, C. A. Hebert, W. L. Wong, M. Alphonso, J. B. Baker, M. A. Catalano, and R. G. Crystal. 1992. Modulation of airway inflammation in cystic fibrosis: in vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor. J. Clin. Invest. 90: 1296-1301.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1296-1301
    • McElvaney, N.G.1    Nakamura, H.2    Birrer, P.3    Hebert, C.A.4    Wong, W.L.5    Alphonso, M.6    Baker, J.B.7    Catalano, M.A.8    Crystal, R.G.9
  • 23
    • 0033570917 scopus 로고    scopus 로고
    • Constitutive silencing of IFN-β promoter is mediated by NRF (NF-κB-repressing factor), a nuclear inhibitor of NF-κB
    • Nourbakhsh, M., and H. Hauser. 1999. Constitutive silencing of IFN-β promoter is mediated by NRF (NF-κB-repressing factor), a nuclear inhibitor of NF-κB. EMBO J. 18: 6415-6425.
    • (1999) EMBO J. , vol.18 , pp. 6415-6425
    • Nourbakhsh, M.1    Hauser, H.2
  • 24
    • 0035830875 scopus 로고    scopus 로고
    • The NF-κB repressing factor is involved in basal repression and interleukin (IL)-1-induced activation of IL-8 transcription by binding to a conserved NF-κB-flanking sequence element
    • Nourbakhsh, M., S. Kalble, A. Dorrie, H. Hauser, K. Resch, and M. Kracht. 2001. The NF-κB repressing factor is involved in basal repression and interleukin (IL)-1-induced activation of IL-8 transcription by binding to a conserved NF-κB-flanking sequence element. J. Biol. Chem. 276: 4501-4508.
    • (2001) J. Biol. Chem. , vol.276 , pp. 4501-4508
    • Nourbakhsh, M.1    Kalble, S.2    Dorrie, A.3    Hauser, H.4    Resch, K.5    Kracht, M.6
  • 25
    • 0037195139 scopus 로고    scopus 로고
    • Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role of NF-κB-repressing factor (NRF) in basal repression of the hiNOS gene
    • Feng, X., Z. Guo, M. Nourbakhsh, H. Hauser, R. Ganster, L. Shao, and D. A. Geller. 2002. Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: the role of NF-κB-repressing factor (NRF) in basal repression of the hiNOS gene. Proc. Natl. Acad. Sci. USA 99: 14212-14217.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14212-14217
    • Feng, X.1    Guo, Z.2    Nourbakhsh, M.3    Hauser, H.4    Ganster, R.5    Shao, L.6    Geller, D.A.7
  • 26
    • 23844501059 scopus 로고    scopus 로고
    • NF-κB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor
    • Dreikhausen, U., K. Hiebenthal-Millow, M. Bartels, K. Resch, and M. Nourbakhsh. 2005. NF-κB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor. Mol. Cell. Biol. 25: 7473-7483.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7473-7483
    • Dreikhausen, U.1    Hiebenthal-Millow, K.2    Bartels, M.3    Resch, K.4    Nourbakhsh, M.5
  • 27
    • 0034779037 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 protein by lipoteichoic acid from Staphylococcus aureus in human pulmonary epithelial cells: Involvement of a nuclear factor κB-dependent pathway
    • Lin, C. H., I. H. Kuan, H. M. Lee, W. S. Lee, J. R. Sheu, Y. S. Ho, C. H. Wang, and H. P. Kuo. 2001. Induction of cyclooxygenase-2 protein by lipoteichoic acid from Staphylococcus aureus in human pulmonary epithelial cells: involvement of a nuclear factor κB-dependent pathway. Br. J. Pharmacol. 134: 543-552.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 543-552
    • Lin, C.H.1    Kuan, I.H.2    Lee, H.M.3    Lee, W.S.4    Sheu, J.R.5    Ho, Y.S.6    Wang, C.H.7    Kuo, H.P.8
  • 28
    • 29644441714 scopus 로고    scopus 로고
    • NF-κB and activator protein 1 response elements and the role of histone modifications in IL-1β-induced TGF-β1 gene transcription
    • Lee, K. Y., K. Ito, R. Hayashi, E. P. Jazrawi, P. J. Barnes, and I. M. Adcock. 2006. NF-κB and activator protein 1 response elements and the role of histone modifications in IL-1β-induced TGF-β1 gene transcription. J. Immunol. 176: 603-615.
    • (2006) J. Immunol. , vol.176 , pp. 603-615
    • Lee, K.Y.1    Ito, K.2    Hayashi, R.3    Jazrawi, E.P.4    Barnes, P.J.5    Adcock, I.M.6
  • 29
    • 33750821379 scopus 로고    scopus 로고
    • IL-1βand TNF-α regulation of the adenosine receptor (A2A) expression: Differential requirement for NF-κB binding to the proximal promoter
    • Morello, S., K. Ito, S. Yamamura, K. Y. Lee, E. Jazrawi, P. Desouza, P. Barnes, C. Cicala, and I. M. Adcock. 2006. IL-1βand TNF-α regulation of the adenosine receptor (A2A) expression: differential requirement for NF-κB binding to the proximal promoter. J. Immunol. 177: 7173-7183.
    • (2006) J. Immunol. , vol.177 , pp. 7173-7183
    • Morello, S.1    Ito, K.2    Yamamura, S.3    Lee, K.Y.4    Jazrawi, E.5    Desouza, P.6    Barnes, P.7    Cicala, C.8    Adcock, I.M.9
  • 30
    • 0027384590 scopus 로고
    • NF-κB subunit-specific regulation of the interleukin-8 promoter
    • Kunsch, C., and C. A. Rosen. 1993. NF-κB subunit-specific regulation of the interleukin-8 promoter. Mol. Cell. Biol. 13: 6137-6146.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6137-6146
    • Kunsch, C.1    Rosen, C.A.2
  • 31
    • 0025601628 scopus 로고
    • Cooperative interaction of nuclear factor κB- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines
    • Mukaida, N., Y. Mahe, and K. Matsushima. 1990. Cooperative interaction of nuclear factor κB- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J. Biol. Chem. 265: 21128-21133.
    • (1990) J. Biol. Chem. , vol.265 , pp. 21128-21133
    • Mukaida, N.1    Mahe, Y.2    Matsushima, K.3
  • 32
    • 0035908126 scopus 로고    scopus 로고
    • Two waves of nuclear factor κB recruitment to target promoters
    • Saccani, S., S. Pantano, and G. Natoli. 2001. Two waves of nuclear factor κB recruitment to target promoters. J. Exp. Med. 193: 1351-1359.
    • (2001) J. Exp. Med. , vol.193 , pp. 1351-1359
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 35
    • 43549103121 scopus 로고    scopus 로고
    • Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells
    • Issa, R., R. Sorrentino, M. B. Sukkar, S. Sriskandan, K. F. Chung, and J. A. Mitchell. 2008. Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells. Respir. Res. 9: 30.
    • (2008) Respir. Res. , vol.9 , pp. 30
    • Issa, R.1    Sorrentino, R.2    Sukkar, M.B.3    Sriskandan, S.4    Chung, K.F.5    Mitchell, J.A.6
  • 37
    • 0030755027 scopus 로고    scopus 로고
    • Transendothelial neutrophil migration: Role of neutrophil-derived proteases and relationship to transendothelial protein movement
    • Cepinskas, G., R. Noseworthy, and P. R. Kvietys. 1997. Transendothelial neutrophil migration: role of neutrophil-derived proteases and relationship to transendothelial protein movement. Circ. Res. 81: 618-626.
    • (1997) Circ. Res. , vol.81 , pp. 618-626
    • Cepinskas, G.1    Noseworthy, R.2    Kvietys, P.R.3
  • 38
    • 0031854869 scopus 로고    scopus 로고
    • Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherins
    • Carden, D., F. Xiao, C. Moak, B. H. Willis, S. Robinson-Jackson, and S. Alexander. 1998. Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherins. Am. J. Physiol. 275: H385-H392.
    • (1998) Am. J. Physiol. , vol.275
    • Carden, D.1    Xiao, F.2    Moak, C.3    Willis, B.H.4    Robinson-Jackson, S.5    Alexander, S.6
  • 41
    • 0025992671 scopus 로고
    • Human neutrophil elastase and elastase/α1-antiprotease complex in cystic fibrosis: Comparison with interstitial lung disease and evaluation of the effect of intravenously administered antibiotic therapy
    • Meyer, K. C., J. R. Lewandoski, J. J. Zimmerman, D. Nunley, W. J. Calhoun, and G. A. Dopico. 1991. Human neutrophil elastase and elastase/α1-antiprotease complex in cystic fibrosis: comparison with interstitial lung disease and evaluation of the effect of intravenously administered antibiotic therapy. Am. Rev. Respir. Dis. 144: 580-585.
    • (1991) Am. Rev. Respir. Dis. , vol.144 , pp. 580-585
    • Meyer, K.C.1    Lewandoski, J.R.2    Zimmerman, J.J.3    Nunley, D.4    Calhoun, W.J.5    Dopico, G.A.6
  • 43
    • 77954067378 scopus 로고    scopus 로고
    • Neutrophil-derived elastase induces NF-κB repressing factor (NRF) expression in airway smooth muscle: The role of NF-κB
    • Lee, K. Y., S. C. Ho, Y. F. Chan, and H. P. Kuo. 2007. Neutrophil-derived elastase induces NF-κB repressing factor (NRF) expression in airway smooth muscle: the role of NF-κB. Am. J. Respir. Crit. Care Med. 175: A664.
    • (2007) Am. J. Respir. Crit. Care Med. , vol.175
    • Lee, K.Y.1    Ho, S.C.2    Chan, Y.F.3    Kuo, H.P.4
  • 44
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin, M. 1995. The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270: 16483-16486.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16483-16486
    • Karin, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.