Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors

Journal of Neuroscience

Volumn 34, Issue 18, 2014, Pages 6352-6366

  Zhong, Peng ^a   Liu, Xiaojie ^a   Zhang, Zhen ^a,b   Hu, Ying ^a   Liu, Sarah J ^a   Lezama Ruiz, Martha ^a   Joksimovic, Milan ^a   Liu, Qing Song ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b Key Laboratory of Cardiovascular Proteomics of Shandong Province   (China)

Author keywords

cAMP; Cdk5; Depression; Dopamine; DREADD; Tyrosine hydroxylase

Indexed keywords

CYCLIC AMP; CYCLIN DEPENDENT KINASE 5; TYROSINE 3 MONOOXYGENASE;

ADULT; ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; CYCLIC POTENTIOMETRY; DEPRESSION; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; ELEVATED PLUS MAZE TEST; ENZYME LINKED IMMUNOSORBENT ASSAY; FORCED SWIM TEST; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; NOVELTY SUPPRESSED FEEDING TEST; NUCLEUS ACCUMBENS; OPEN FIELD TEST; PHOSPHORYLATION; PRIORITY JOURNAL; SUCROSE PREFERENCE TEST; VENTRAL TEGMENTUM; WESTERN BLOTTING;

CAMP; CDK5; DEPRESSION; DOPAMINE; DREADD; TYROSINE HYDROXYLASE;

ANIMALS; ANTIPSYCHOTIC AGENTS; CLOZAPINE; CREB-BINDING PROTEIN; CYCLIC AMP; CYCLIN-DEPENDENT KINASE 5; DEPRESSION; DISEASE MODELS, ANIMAL; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; EXPLORATORY BEHAVIOR; FOOD PREFERENCES; GREEN FLUORESCENT PROTEINS; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, UNTRANSLATED; SERINE; VENTRAL TEGMENTAL AREA;

EID: 84899637787     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3673-13.2014     Document Type: Article

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