A Gα;s DREADD mouse for selective modulation of cAMP production in striatopallidal neurons

Neuropsychopharmacology

Volumn 38, Issue 5, 2013, Pages 854-862

  Farrell, Martilias S ^a   Pei, Ying ^a   Wan, Yehong ^b   Yadav, Prem N ^a   Daigle, Tanya L ^b   Urban, Daniel J ^a   Lee, Hyeong Min ^a   Sciaky, Noah ^a   Simmons, Arkeen ^c   Nonneman, Randal J ^a   Huang, Xi Ping ^a   Hufeisen, Sandy J ^a   Guettier, Jean Marc ^d   Moy, Sheryl S ^a   Wess, Jürgen ^d   Caron, Marc G ^b   Calakos, Nicole ^b   Roth, Bryan L ^a,e  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c ELIZABETH CITY STATE UNIVERSITY   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

amphetamine; DREADD; G alpha s; Gs; striatopallidal; striatum

Indexed keywords

AMPHETAMINE; CLOZAPINE N OXIDE; COCAINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DESIGNER DRUG; DESIGNER RECEPTOR EXCLUSIVELY ACTIVATED BY DESIGNER DRUG; PHOSPHOPROTEIN DARPP 32; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENOTYPE; IN VITRO STUDY; IN VIVO STUDY; LOCOMOTION; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SENSITIZATION; SIGNAL TRANSDUCTION; STRIATE CORTEX; SYNAPTIC TRANSMISSION; TRANSGENE; TRANSGENIC MOUSE;

ADRENERGIC UPTAKE INHIBITORS; AMPHETAMINE; ANIMALS; ANIMALS, NEWBORN; CLOZAPINE; COCAINE; CORPUS STRIATUM; CYCLIC AMP; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; DOPAMINE UPTAKE INHIBITORS; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; LOCOMOTION; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; PHOSPHORYLATION; RECEPTOR, ADENOSINE A2A; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, MUSCARINIC;

EID: 84875210398     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.251     Document Type: Article

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