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Volumn 15, Issue 6, 2012, Pages 795-809

Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behaviour in rats

Author keywords

Butyrolactone; Cdk5; chronic mild stress; depression; p35

Indexed keywords

ARIPIPRAZOLE; CYCLIN DEPENDENT KINASE 5; MIRTAZAPINE; PROTEIN P35; VENLAFAXINE;

EID: 84862125015     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145711000915     Document Type: Article
Times cited : (45)

References (63)
  • 1
    • 33846040831 scopus 로고    scopus 로고
    • Trekking across the Brain: The Journey of Neuronal Migration
    • DOI 10.1016/j.cell.2006.12.021, PII S0092867406016485
    • Ayala R, Shu T, Tsai LH (2007). Trekking across the brain : the journey of neuronal migration. Cell 128, 29-43. (Pubitemid 46055273)
    • (2007) Cell , vol.128 , Issue.1 , pp. 29-43
    • Ayala, R.1    Shu, T.2    Tsai, L.-H.3
  • 2
    • 0033167050 scopus 로고    scopus 로고
    • Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS
    • DOI 10.1016/S0278-5846(99)00044-5, PII S0278584699000445
    • Bajaj NP, al-Sarraj ST, Leigh PN, Anderson V, et al. (1999). Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS. Progress in Neuro-Psychopharmacology and Biological Psychiatry 23, 833-850. (Pubitemid 29416758)
    • (1999) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.23 , Issue.5 , pp. 833-850
    • Bajaj, N.P.S.1    Al-Sarraj, S.T.2    Leigh, P.N.3    Anderson, V.4    Miller, C.C.J.5
  • 4
    • 0028828550 scopus 로고
    • Cortical and brainstem-type Lewy bodies are immunoreactive for the cyclin-dependent kinase 5
    • Brion JP, Couck AM (1995). Cortical and brainstem-type Lewy bodies are immunoreactive for the cyclin-dependent kinase 5. American Journal of Pathology 147, 1465-1476.
    • (1995) American Journal of Pathology , vol.147 , pp. 1465-1476
    • Brion, J.P.1    Couck, A.M.2
  • 5
    • 1842481232 scopus 로고    scopus 로고
    • Lower Hippocampal Volume in Patients Suffering from depression: A Meta-Analysis
    • DOI 10.1176/appi.ajp.161.4.598
    • Campbell S, Marriott M, Nahmias C, MacQueenGM(2004). Lower hippocampal volume in patients suffering from depression: a meta-analysis. American Journal of Psychiatry 161, 598-607. (Pubitemid 38445502)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.4 , pp. 598-607
    • Campbell, S.1    Marriott, M.2    Nahmias, C.3    MacQueen, G.M.4
  • 6
    • 0035338399 scopus 로고    scopus 로고
    • Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect
    • DOI 10.1016/S0006-3223(00)01114-8, PII S0006322300011148
    • Chen AC, Shirayama Y, Shin KH, Neve RL, et al. (2001a). Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect. Biological Psychiatry 49, 753-762. (Pubitemid 32452296)
    • (2001) Biological Psychiatry , vol.49 , Issue.9 , pp. 753-762
    • Chen, A.C.-H.1    Shirayama, Y.2    Shin, K.-H.3    Neve, R.L.4    Duman, R.S.5
  • 7
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • DOI 10.1016/S0006-3223(01)01083-6, PII S0006322301010836
    • Chen B, Dowlatshahi D, MacQueen GM, Wang JF, et al. (2001b). Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biological Psychiatry 50, 260-265. (Pubitemid 32778442)
    • (2001) Biological Psychiatry , vol.50 , Issue.4 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3    Wang, J.-F.4    Young L.Trevor5
  • 8
    • 0034671284 scopus 로고    scopus 로고
    • Induction of cyclin-dependent kinase 5 in the hippocampus by chronic electroconvulsive seizures: Role of δFosB
    • Chen J, Zhang Y, Kelz MB, Steffen C, et al. (2000). Induction of cyclin-dependent kinase 5 in the hippocampus by chronic electroconvulsive seizures : role of [Delta]FosB. Journal of Neuroscience 20, 8965-8971. (Pubitemid 32042896)
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 8965-8971
    • Chen, J.1    Zhang, Y.2    Kelz, M.B.3    Steffen, C.4    Ang, E.S.5    Zeng, L.6    Nestler, E.J.7
  • 9
    • 13944249205 scopus 로고    scopus 로고
    • Enhanced Cdk5 activity and p35 translocation in the ventral striatum of acute and chronic methamphetamine-treated rats
    • Chen PC, Chen JC (2005). Enhanced Cdk5 activity and p35 translocation in the ventral striatum of acute and chronic methamphetamine-treated rats. Neuropsychopharmacology 30, 538-549.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 538-549
    • Chen, P.C.1    Chen, J.C.2
  • 10
    • 60849109938 scopus 로고    scopus 로고
    • Chronic stress-induced hippocampal vulnerability : The glucocorticoid vulnerability hypothesis
    • Conrad CD (2008). Chronic stress-induced hippocampal vulnerability : the glucocorticoid vulnerability hypothesis. Reviews in the Neurosciences 19, 395-411.
    • (2008) Reviews in the Neurosciences , vol.19 , pp. 395-411
    • Conrad, C.D.1
  • 11
    • 0345405447 scopus 로고    scopus 로고
    • Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
    • DOI 10.1016/S0896-6273(03)00627-5
    • Cruz JC, Tseng HC, Goldman JA, Shih H, et al. (2003). Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron 40, 471-483. (Pubitemid 37494698)
    • (2003) Neuron , vol.40 , Issue.3 , pp. 471-483
    • Cruz, J.C.1    Tseng, H.-C.2    Goldman, J.A.3    Shih, H.4    Tsai, L.-H.5
  • 13
    • 1642307557 scopus 로고    scopus 로고
    • Role of neurotrophic factors in the etiology and treatment of mood disorders
    • Duman RS (2004). Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Medicine 5, 11-25. (Pubitemid 38391953)
    • (2004) NeuroMolecular Medicine , vol.5 , Issue.1 , pp. 11-25
    • Duman, R.S.1
  • 14
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman RS, Monteggia LM (2006). A neurotrophic model for stress-related mood disorders. Biological Psychiatry 59, 1116-1127.
    • (2006) Biological Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 15
    • 28744449248 scopus 로고    scopus 로고
    • Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory
    • DOI 10.1016/j.neuron.2005.10.033, PII S0896627305009517
    • Fischer A, Sananbenesi F, Pang PT, Lu B, et al. (2005). Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron 48, 825-838. (Pubitemid 41759432)
    • (2005) Neuron , vol.48 , Issue.5 , pp. 825-838
    • Fischer, A.1    Sananbenesi, F.2    Pang, P.T.3    Lu, B.4    Tsai, L.-H.5
  • 18
    • 0037431130 scopus 로고    scopus 로고
    • Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis
    • DOI 10.1016/S0896-6273(03)00191-0
    • Gong X, Tang X, Wiedmann M, Wang X, et al. (2003). Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis. Neuron 38, 33-46. (Pubitemid 36423351)
    • (2003) Neuron , vol.38 , Issue.1 , pp. 33-46
    • Gong, X.1    Tang, X.2    Wiedmann, M.3    Wang, X.4    Peng, J.5    Zheng, D.6    Blair, L.A.C.7    Marshall, J.8    Mao, Z.9
  • 19
    • 0035798093 scopus 로고    scopus 로고
    • The neurobiology of slow synaptic transmission
    • DOI 10.1126/science.294.5544.1024
    • Greengard P (2001). The neurobiology of slow synaptic transmission. Science 294, 1024-1030. (Pubitemid 33041850)
    • (2001) Science , vol.294 , Issue.5544 , pp. 1024-1030
    • Greengard, P.1
  • 20
    • 0028175963 scopus 로고
    • The apoptotic suppressor P35 is required early during baculovirus replication and is targeted to the cytosol of infected cells
    • Hershberger PA, LaCount DJ, Friesen PD (1994). The apoptotic suppressor P35 is required early during baculovirus replication and is targeted to the cytosol of infected cells. Journal of Virology 68, 3467-3477.
    • (1994) Journal of Virology , vol.68 , pp. 3467-3477
    • Hershberger, P.A.1    Lacount, D.J.2    Friesen, P.D.3
  • 21
    • 0027990255 scopus 로고
    • A cyclin-dependent kinase inhibitor, butyrolactone I, inhibits phosphorylation of RB protein and cell cycle progression
    • Kitagawa M, Higashi H, Takahashi IS, Okabe T, et al. (1994). A cyclin-dependent kinase inhibitor, butyrolactone I, inhibits phosphorylation of RB protein and cell cycle progression. Oncogene 9, 2549-2557. (Pubitemid 24254030)
    • (1994) Oncogene , vol.9 , Issue.9 , pp. 2549-2557
    • Kitagawa, M.1    Higashi, H.2    Takahashi, I.S.3    Okabe, T.4    Ogino, H.5    Taya, Y.6    Nishimura, S.7    Okuyama, A.8
  • 23
    • 0034682414 scopus 로고    scopus 로고
    • Neurotoxicity induces cleavage of p35 to p25 by calpain
    • DOI 10.1038/35012636
    • Lee M, Kwon YT, Li M, Peng J, et al. (2000). Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 405, 360-364. (Pubitemid 30337070)
    • (2000) Nature , vol.405 , Issue.6784 , pp. 360-364
    • Lee, M.-S.1    Kwon, Y.T.2    Li, M.3    Peng, J.4    Friedlander, R.M.5    Tsai, L.-H.6
  • 25
    • 0036469286 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3
    • DOI 10.1093/emboj/21.3.324
    • Li BS, Zhang L, Takahashi S, Ma W, et al. (2002). Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3. EMBO Journal 21, 324-333. (Pubitemid 34137294)
    • (2002) EMBO Journal , vol.21 , Issue.3 , pp. 324-333
    • Li, B.-S.1    Zhang, L.2    Takahashi, S.3    Ma, W.4    Jaffe, H.5    Kulkarni, A.B.6    Pant, H.C.7
  • 26
    • 77955361715 scopus 로고    scopus 로고
    • Basolateral amygdala cdk5 activity mediates consolidation and reconsolidation of memories for cocaine cues
    • Li FQ, Xue YX, Wang JS, Fang Q, et al. (2010). Basolateral amygdala cdk5 activity mediates consolidation and reconsolidation of memories for cocaine cues. Journal of Neuroscience 30, 10351-10359.
    • (2010) Journal of Neuroscience , vol.30 , pp. 10351-10359
    • Li, F.Q.1    Xue, Y.X.2    Wang, J.S.3    Fang, Q.4
  • 27
    • 58149390176 scopus 로고    scopus 로고
    • Central amygdala extracellular signal-regulated kinase signaling pathway is critical to incubation of opiate craving
    • Li YQ, Li FQ, Wang XY, Wu P, et al. (2008). Central amygdala extracellular signal-regulated kinase signaling pathway is critical to incubation of opiate craving. Journal of Neuroscience 28, 13248-13257.
    • (2008) Journal of Neuroscience , vol.28 , pp. 13248-13257
    • Li, Y.Q.1    Li, F.Q.2    Wang, X.Y.3    Wu, P.4
  • 28
    • 26944458498 scopus 로고    scopus 로고
    • Effect of chronic unpredictable mild stress on brain-pancreas relative protein in rat brain and pancreas
    • DOI 10.1016/j.bbr.2005.06.034, PII S0166432805002810
    • Lin YH, Liu AH, Xu Y, Tie L, et al. (2005). Effect of chronic unpredictable mild stress on brain-pancreas relative protein in rat brain and pancreas. Behavioural Brain Research 165, 63-71. (Pubitemid 41476205)
    • (2005) Behavioural Brain Research , vol.165 , Issue.1 , pp. 63-71
    • Lin, Y.-H.1    Liu, A.-H.2    Xu, Y.3    Tie, L.4    Yu, H.-M.5    Li, X.-J.6
  • 30
    • 0028878537 scopus 로고
    • Detection of a Cdc2-related kinase associated with Alzheimer paired helical filaments
    • Liu WK, Williams RT, Hall FL, Dickson DW, et al. (1995). Detection of a Cdc2-related kinase associated with Alzheimer paired helical filaments. American Journal of Pathology 146, 228-238.
    • (1995) American Journal of Pathology , vol.146 , pp. 228-238
    • Liu, W.K.1    Williams, R.T.2    Hall, F.L.3    Dickson, D.W.4
  • 31
    • 13244275191 scopus 로고    scopus 로고
    • Central amygdala ERK signaling pathway is critical to incubation of cocaine craving
    • DOI 10.1038/nn1383
    • Lu L, Hope BT, Dempsey J, Liu SY, et al. (2005). Central amygdala ERK signaling pathway is critical to incubation of cocaine craving. Nature Neuroscience 8, 212-219. (Pubitemid 40194052)
    • (2005) Nature Neuroscience , vol.8 , Issue.2 , pp. 212-219
    • Lu, L.1    Hope, B.T.2    Dempsey, J.3    Liu, S.Y.4    Bessert, J.M.5    Shaham, Y.6
  • 32
    • 51749098425 scopus 로고    scopus 로고
    • Involvement of hippocampal serotonin and neuropeptide y in depression induced by chronic unpredicted mild stress
    • Luo DD, An SC, Zhang X (2008). Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain Research Bulletin 77, 8-12.
    • (2008) Brain Research Bulletin , vol.77 , pp. 8-12
    • Luo, D.D.1    An, S.C.2    Zhang, X.3
  • 33
    • 0032912252 scopus 로고    scopus 로고
    • Stress and hippocampal plasticity
    • DOI 10.1146/annurev.neuro.22.1.105
    • McEwen BS (1999). Stress and hippocampal plasticity. Annual Review of Neuroscience 22, 105-122. (Pubitemid 29144882)
    • (1999) Annual Review of Neuroscience , vol.22 , pp. 105-122
    • McEwen, B.S.1
  • 34
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
    • DOI 10.1016/S0140-6736(96)07492-2
    • Murray CJ, Lopez AD (1997). Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504. (Pubitemid 27216360)
    • (1997) Lancet , vol.349 , Issue.9064 , pp. 1498-1504
    • Murray, C.J.L.1    Lopez, A.D.2
  • 35
    • 0031842931 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 and mitogen-activated protein kinase in glial cytoplasmic inclusions in multiple system atrophy
    • Nakamura S, Kawamoto Y, Nakano S, Akiguchi I, et al. (1998). Cyclin-dependent kinase 5 and mitogen-activated protein kinase in glial cytoplasmic inclusions in multiple system atrophy. Journal of Neuropathology and Experimental Neurology 57, 690-698. (Pubitemid 28335058)
    • (1998) Journal of Neuropathology and Experimental Neurology , vol.57 , Issue.7 , pp. 690-698
    • Nakamura, S.1    Kawamoto, Y.2    Nakano, S.3    Akiguchi, I.4    Kimura, J.5
  • 36
    • 0031019362 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 in Lewy body-like inclusions in anterior horn cells of a patient with sporadic amyotrophic lateral sclerosis
    • Nakamura S, Kawamoto Y, Nakano S, Ikemoto A, et al. (1997). Cyclin-dependent kinase 5 in Lewy body-like inclusions in anterior horn cells of a patient with sporadic amyotrophic lateral sclerosis. Neurology 48, 267-270. (Pubitemid 27039555)
    • (1997) Neurology , vol.48 , Issue.1 , pp. 267-270
    • Nakamura, S.1    Kawamoto, Y.2    Nakano, S.3    Ikemoto, A.4    Akiguchi, I.5    Kimura, J.6
  • 37
    • 17744368458 scopus 로고    scopus 로고
    • Deregulation of Cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
    • DOI 10.1016/S0896-6273(01)00268-9
    • Nguyen MD, Lariviere RC, Julien JP (2001). Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 30, 135-147. (Pubitemid 32441682)
    • (2001) Neuron , vol.30 , Issue.1 , pp. 135-147
    • Nguyen, M.D.1    Lariviere, R.C.2    Julien, J.-P.3
  • 38
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M, Morinobu S, Duman RS (1995). Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. Journal of Neuroscience 15, 7539-7547.
    • (1995) Journal of Neuroscience , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 40
    • 0025909324 scopus 로고
    • An animal model of anhedonia: Attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress
    • Papp M, Willner P, Muscat R (1991). An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress. Psychopharmacology (Berlin) 104, 255-259.
    • (1991) Psychopharmacology (Berlin) , vol.104 , pp. 255-259
    • Papp, M.1    Willner, P.2    Muscat, R.3
  • 41
    • 0033540060 scopus 로고    scopus 로고
    • Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
    • Patrick GN, Zukerberg L, Nikolic M, de la Monte S, et al. (1999). Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 402, 615-622. (Pubitemid 129516324)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 615-622
    • Patrick, G.N.1    Zukerberg, L.2    Nikolic, M.3    De La Monte, S.4    Dikkes, P.5    Tsai, L.-H.6
  • 42
    • 0019293220 scopus 로고
    • AChE-stained horizontal sections of the rat brain in stereotaxis coordinates
    • DOI 10.1016/0165-0270(80)90021-7
    • Paxinos G, Watson CR, Emson PC (1980). AChE-stained horizontal sections of the rat brain in stereotaxic coordinates. Journal of Neuroscience Methods 3, 129-149. (Pubitemid 11162950)
    • (1980) Journal of Neuroscience Methods , vol.3 , Issue.2 , pp. 129-149
    • Paxinos, G.1    Watson, C.2    Emson, P.C.3
  • 43
    • 0035906522 scopus 로고    scopus 로고
    • Neuroprotection with herpes simplex vectors expressing virally derived anti-apoptotic agents
    • DOI 10.1016/S0006-8993(01)02034-0, PII S0006899301020340
    • Roy M, Hom J, Sapolsky RM (2001). Neuroprotection with herpes simplex vectors expressing virally derived antiapoptotic agents. Brain Research 901, 12-22. (Pubitemid 32718800)
    • (2001) Brain Research , vol.901 , Issue.1-2 , pp. 12-22
    • Roy, M.1    Hom, J.2    Sapolsky, R.M.3
  • 44
    • 0036184826 scopus 로고    scopus 로고
    • HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic discruption
    • DOI 10.1038/sj/gt/3301642
    • Roy M, Hom JJ, Sapolsky RM (2002). HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic disruption. Gene Therapy 9, 214-219. (Pubitemid 34189582)
    • (2002) Gene Therapy , vol.9 , Issue.3 , pp. 214-219
    • Roy, M.1    Hom, J.J.2    Sapolsky, R.M.3
  • 45
    • 0041833483 scopus 로고    scopus 로고
    • The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult
    • DOI 10.1016/S0969-9961(03)00083-4
    • Roy M, Sapolsky RM (2003). The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult. Neurobiology of Disease 14, 1-9. (Pubitemid 37103174)
    • (2003) Neurobiology of Disease , vol.14 , Issue.1 , pp. 1-9
    • Roy, M.1    Sapolsky, R.M.2
  • 47
    • 34548395111 scopus 로고    scopus 로고
    • The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
    • DOI 10.1097/FBP.0b013e3282ee2aa8, PII 0000887720070900000008
    • Schmidt HD, Duman RS (2007). The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behavioural Pharmacology 18, 391-418. (Pubitemid 47356367)
    • (2007) Behavioural Pharmacology , vol.18 , Issue.5-6 , pp. 391-418
    • Schmidt, H.D.1    Duman, R.S.2
  • 48
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y, Chen AC, Nakagawa S, Russell DS, et al. (2002). Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. Journal of Neuroscience 22, 3251-3261. (Pubitemid 35379212)
    • (2002) Journal of Neuroscience , vol.22 , Issue.8 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.-H.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 49
    • 0036169172 scopus 로고    scopus 로고
    • Cdk5 behind the wheel: A role in trafficking and transport?
    • DOI 10.1016/S0962-8924(01)02181-X, PII S096289240102181X
    • Smith DS, Tsai LH (2002). Cdk5 behind the wheel: a role in trafficking and transport? Trends in Cell Biology 12, 28-36. (Pubitemid 34164154)
    • (2002) Trends in Cell Biology , vol.12 , Issue.1 , pp. 28-36
    • Smith, D.S.1    Tsai, L.-H.2
  • 51
    • 0033987059 scopus 로고    scopus 로고
    • Cdk5 and munc-18/p67 co-localization in early stage neurofibrillary tangles-bearing neurons in Alzheimer type dementia brains
    • DOI 10.1016/S0022-510X(99)00291-9, PII S0022510X99002919
    • Takahashi M, Iseki E, Kosaka K (2000). Cdk5 and munc-18/p67 co-localization in early stage neurofibrillary tangles-bearing neurons in Alzheimer type dementia brains. Journal of Neuroscience 172, 63-69. (Pubitemid 30006983)
    • (2000) Journal of the Neurological Sciences , vol.172 , Issue.1 , pp. 63-69
    • Takahashi, M.1    Iseki, E.2    Kosaka, K.3
  • 53
    • 0027978170 scopus 로고
    • P35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
    • DOI 10.1038/371419a0
    • Tsai LH, Delalle I, Caviness VS, Chae T, et al. (1994). p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature 371, 419-423. (Pubitemid 24302556)
    • (1994) Nature , vol.371 , Issue.6496 , pp. 419-423
    • Teai, L.-H.1    Delalle, I.2    Cavness Jr., V.S.3    Chae, T.4    Harlow, E.5
  • 54
    • 33749389928 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity
    • DOI 10.1074/jbc.M604690200
    • Ubeda M, Rukstalis JM, Habener JF (2006). Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity. Journal of Biological Chemistry 281, 28858-28864. (Pubitemid 44507029)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.39 , pp. 28858-28864
    • Ubeda, M.1    Rukstalis, J.M.2    Habener, J.F.3
  • 55
    • 0043268822 scopus 로고    scopus 로고
    • Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons
    • DOI 10.1016/S0306-4522(03)00355-5
    • Van Riel E, Meijer OC, Steenbergen PJ, Joels M (2003). Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons. Neuroscience 120, 649-658. (Pubitemid 36928063)
    • (2003) Neuroscience , vol.120 , Issue.3 , pp. 649-658
    • Van Riel, E.1    Meijer, O.C.2    Steenbergen, P.J.3    Joels, M.4
  • 56
    • 7444255996 scopus 로고    scopus 로고
    • Hippocampal volume and depression: A meta-analysis of MRI studies
    • DOI 10.1176/appi.ajp.161.11.1957
    • Videbech P, Ravnkilde B (2004). Hippocampal volume and depression: a meta-analysis of MRI studies. American Journal of Psychiatry 161, 1957-1966. (Pubitemid 39441394)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.11 , pp. 1957-1966
    • Videbech, P.1    Ravnkilde, B.2
  • 57
    • 58849095405 scopus 로고    scopus 로고
    • CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits
    • Wallace DL, Han MH, Graham DL, Green TA, et al. (2009). CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits. Nature Neuroscience 12, 200-209.
    • (2009) Nature Neuroscience , vol.12 , pp. 200-209
    • Wallace, D.L.1    Han, M.H.2    Graham, D.L.3    Green, T.A.4
  • 58
    • 39149100296 scopus 로고    scopus 로고
    • Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor
    • Wang D, An SC, Zhang X (2008). Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor. Neuroscience Letters 433, 59-64.
    • (2008) Neuroscience Letters , vol.433 , pp. 59-64
    • Wang, D.1    An, S.C.2    Zhang, X.3
  • 59
    • 20344388665 scopus 로고    scopus 로고
    • Kainic acid-mediated excitotoxicity as a model for neurodegeneration
    • Wang Q, Yu S, Simonyi A, Sun GY, et al. (2005). Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Molecular Neurobiology 31, 3-16. (Pubitemid 41271190)
    • (2005) Molecular Neurobiology , vol.31 , Issue.1-3 , pp. 3-16
    • Wang, Q.1    Yu, S.2    Simonyi, A.3    Sun, G.Y.4    Sun, A.Y.5
  • 60
    • 77957193584 scopus 로고    scopus 로고
    • Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats
    • Wang X, Luo YX, He YY, Li FQ, et al. (2010). Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats. Journal of Neuroscience 30, 12632-12641.
    • (2010) Journal of Neuroscience , vol.30 , pp. 12632-12641
    • Wang, X.1    Luo, Y.X.2    He, Y.Y.3    Li, F.Q.4
  • 61
    • 33645109592 scopus 로고    scopus 로고
    • Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment
    • Warner-Schmidt JL, Duman RS (2006). Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 16, 239-249.
    • (2006) Hippocampus , vol.16 , pp. 239-249
    • Warner-Schmidt, J.L.1    Duman, R.S.2
  • 62
    • 0031440325 scopus 로고    scopus 로고
    • Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation
    • DOI 10.1007/s002130050456
    • Willner P (1997). Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berlin) 134, 319-329. (Pubitemid 28023396)
    • (1997) Psychopharmacology , vol.134 , Issue.4 , pp. 319-329
    • Willner, P.1
  • 63
    • 0023636527 scopus 로고
    • Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
    • Willner P, Towell A, Sampson D, Sophokleous S, et al. (1987). Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology (Berlin) 93, 358-364. (Pubitemid 17160661)
    • (1987) Psychopharmacology , vol.93 , Issue.3 , pp. 358-364
    • Willner, P.1    Towell, A.2    Sampson, D.3    Sophokleous, S.4    Muscat, R.5


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