메뉴 건너뛰기




Volumn 6, Issue 4, 2014, Pages 1397-1418

Immunogenicity of a west nile virus DIII-cholera toxin A2/B chimera after intranasal delivery

Author keywords

Cholera toxin; Mucosal adjuvant; Vaccine; West Nile virus

Indexed keywords

CHOLERA TOXIN B SUBUNIT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M ANTIBODY; CHOLERA TOXIN; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; RECOMBINANT VACCINE; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN; WEST NILE VACCINE;

EID: 84899625132     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins6041397     Document Type: Article
Times cited : (16)

References (97)
  • 1
    • 0001609777 scopus 로고
    • A neuotropic virus isolated from the blood of a native of Uganda
    • Smithburn, K.C.; Hughes, T.P.; Burke, A.W.; Paul, K.C. A neuotropic virus isolated from the blood of a native of Uganda. Am. J. Trop. Med. 1940, 20, 471-492.
    • (1940) Am. J. Trop. Med. , vol.20 , pp. 471-492
    • Smithburn, K.C.1    Hughes, T.P.2    Burke, A.W.3    Paul, K.C.4
  • 4
    • 84877864025 scopus 로고    scopus 로고
    • Resurgence of West Nile neurologic disease in the United States in 2012: What happened? What needs to be done?
    • Beasley, D.W.; Barrett, A.D.; Tesh, R.B. Resurgence of West Nile neurologic disease in the United States in 2012: What happened? What needs to be done? Antiviral Res. 2013, 99, 1-5.
    • (2013) Antiviral Res. , vol.99 , pp. 1-5
    • Beasley, D.W.1    Barrett, A.D.2    Tesh, R.B.3
  • 6
    • 0037031280 scopus 로고    scopus 로고
    • West Nile virus: A primer for the clinician
    • Petersen, L.R.; Marfin, A.A. West Nile virus: A primer for the clinician. Ann. Intern. Med. 2002, 137, 173-179.
    • (2002) Ann. Intern. Med. , vol.137 , pp. 173-179
    • Petersen, L.R.1    Marfin, A.A.2
  • 8
    • 84863756875 scopus 로고    scopus 로고
    • Medical risk factors for severe west nile virus disease, United States, 2008-2010
    • Lindsey, N.P.; Staples, J.E.; Lehman, J.A.; Fischer, M. Medical risk factors for severe west nile virus disease, United States, 2008-2010. Am. J. Trop. Med. Hyg. 2012, 87, 179-184.
    • (2012) Am. J. Trop. Med. Hyg. , vol.87 , pp. 179-184
    • Lindsey, N.P.1    Staples, J.E.2    Lehman, J.A.3    Fischer, M.4
  • 9
    • 84859803374 scopus 로고    scopus 로고
    • Delayed mortality in a cohort of persons hospitalized with West Nile virus disease in Colorado in 2003
    • Lindsey, N.P.; Sejvar, J.J.; Bode, A.V.; Pape, W.J.; Campbell, G.L. Delayed mortality in a cohort of persons hospitalized with West Nile virus disease in Colorado in 2003. Vector Borne Zoonotic Dis. 2012, 12, 230-235.
    • (2012) Vector Borne Zoonotic Dis. , vol.12 , pp. 230-235
    • Lindsey, N.P.1    Sejvar, J.J.2    Bode, A.V.3    Pape, W.J.4    Campbell, G.L.5
  • 10
    • 0037319970 scopus 로고    scopus 로고
    • B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus
    • Diamond, M.S.; Shrestha, B.; Marri, A.; Mahan, D.; Engle, M. B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus. J. Virol. 2003, 77, 2578-2586.
    • (2003) J. Virol. , vol.77 , pp. 2578-2586
    • Diamond, M.S.1    Shrestha, B.2    Marri, A.3    Mahan, D.4    Engle, M.5
  • 11
    • 0034740861 scopus 로고    scopus 로고
    • Interleukin-1beta but not tumor necrosis factor is involved in West Nile virus-induced Langerhans cell migration from the skin in C57BL/6 mice
    • Byrne, S.N.; Halliday, G.M.; Johnston, L.J.; King, N.J. Interleukin-1beta but not tumor necrosis factor is involved in West Nile virus-induced Langerhans cell migration from the skin in C57BL/6 mice. J. Invest. Dermatol. 2001, 117, 702-709.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 702-709
    • Byrne, S.N.1    Halliday, G.M.2    Johnston, L.J.3    King, N.J.4
  • 12
    • 0034097874 scopus 로고    scopus 로고
    • Langerhans cells migrate to local lymph nodes following cutaneous infection with an arbovirus
    • Johnston, L.J.; Halliday, G.M.; King, N.J. Langerhans cells migrate to local lymph nodes following cutaneous infection with an arbovirus. J. Invest. Dermatol. 2000, 114, 560-568.
    • (2000) J. Invest. Dermatol. , vol.114 , pp. 560-568
    • Johnston, L.J.1    Halliday, G.M.2    King, N.J.3
  • 13
    • 0141925650 scopus 로고    scopus 로고
    • Innate and adaptive immune responses determine protection against disseminated infection by West Nile encephalitis virus
    • Diamond, M.S.; Shrestha, B.; Mehlhop, E.; Sitati, E.; Engle, M. Innate and adaptive immune responses determine protection against disseminated infection by West Nile encephalitis virus. Viral Immunol. 2003, 16, 259-278.
    • (2003) Viral Immunol. , vol.16 , pp. 259-278
    • Diamond, M.S.1    Shrestha, B.2    Mehlhop, E.3    Sitati, E.4    Engle, M.5
  • 14
    • 0347593991 scopus 로고    scopus 로고
    • A critical role for induced IgM in the protection against West Nile virus infection
    • Diamond, M.S.; Sitati, E.M.; Friend, L.D.; Higgs, S.; Shrestha, B.; Engle, M. A critical role for induced IgM in the protection against West Nile virus infection. J. Exp. Med. 2003, 198, 1853-1862.
    • (2003) J. Exp. Med. , vol.198 , pp. 1853-1862
    • Diamond, M.S.1    Sitati, E.M.2    Friend, L.D.3    Higgs, S.4    Shrestha, B.5    Engle, M.6
  • 16
    • 33748933523 scopus 로고    scopus 로고
    • Pathogenesis of West Nile Virus infection: A balance between virulence, innate and adaptive immunity, and viral evasion
    • Samuel, M.A.; Diamond, M.S. Pathogenesis of West Nile Virus infection: A balance between virulence, innate and adaptive immunity, and viral evasion. J. Virol. 2006, 80, 9349-9360.
    • (2006) J. Virol. , vol.80 , pp. 9349-9360
    • Samuel, M.A.1    Diamond, M.S.2
  • 17
    • 40849107822 scopus 로고    scopus 로고
    • The relative contribution of antibody and CD8+ T cells to vaccine immunity against West Nile encephalitis virus
    • Shrestha, B.; Ng, T.; Chu, H.J.; Noll, M.; Diamond, M.S. The relative contribution of antibody and CD8+ T cells to vaccine immunity against West Nile encephalitis virus. Vaccine 2008, 26, 2020-2033.
    • (2008) Vaccine , vol.26 , pp. 2020-2033
    • Shrestha, B.1    Ng, T.2    Chu, H.J.3    Noll, M.4    Diamond, M.S.5
  • 18
    • 52049125010 scopus 로고    scopus 로고
    • The structural immunology of antibody protection against West Nile virus
    • Diamond, M.S.; Pierson, T.C.; Fremont, D.H. The structural immunology of antibody protection against West Nile virus. Immunol. Rev. 2008, 225, 212-225.
    • (2008) Immunol. Rev. , vol.225 , pp. 212-225
    • Diamond, M.S.1    Pierson, T.C.2    Fremont, D.H.3
  • 19
    • 13644262812 scopus 로고    scopus 로고
    • Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein
    • Chu, J.J.; Rajamanonmani, R.; Li, J.; Bhuvanakantham, R.; Lescar, J.; Ng, M.L. Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein. J. Gen. Virol. 2005, 86, 405-412.
    • (2005) J. Gen. Virol. , vol.86 , pp. 405-412
    • Chu, J.J.1    Rajamanonmani, R.2    Li, J.3    Bhuvanakantham, R.4    Lescar, J.5    Ng, M.L.6
  • 21
    • 26944454471 scopus 로고    scopus 로고
    • Structural basis of West Nile virus neutralization by a therapeutic antibody
    • Nybakken, G.E.; Oliphant, T.; Johnson, S.; Burke, S.; Diamond, M.S.; Fremont, D.H. Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature 2005, 437, 764-769.
    • (2005) Nature , vol.437 , pp. 764-769
    • Nybakken, G.E.1    Oliphant, T.2    Johnson, S.3    Burke, S.4    Diamond, M.S.5    Fremont, D.H.6
  • 22
    • 0036891872 scopus 로고    scopus 로고
    • Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein
    • Beasley, D.W.; Barrett, A.D. Identification of neutralizing epitopes within structural domain III of the West Nile virus envelope protein. J. Virol. 2002, 76, 13097-13100.
    • (2002) J. Virol. , vol.76 , pp. 13097-13100
    • Beasley, D.W.1    Barrett, A.D.2
  • 24
    • 79951766069 scopus 로고    scopus 로고
    • Vaccines and immunotherapeutics for the prevention and treatment of infections with West Nile virus
    • Beasley, D.W. Vaccines and immunotherapeutics for the prevention and treatment of infections with West Nile virus. Immunotherapy 2011, 3, 269-285.
    • (2011) Immunotherapy , vol.3 , pp. 269-285
    • Beasley, D.W.1
  • 26
    • 84884936666 scopus 로고    scopus 로고
    • Vaccines in development against West Nile virus
    • Brandler, S.; Tangy, F. Vaccines in development against West Nile virus. Viruses 2013, 5, 2384-2409.
    • (2013) Viruses , vol.5 , pp. 2384-2409
    • Brandler, S.1    Tangy, F.2
  • 28
    • 79957592934 scopus 로고    scopus 로고
    • Safety and immunogenicity of a chimeric vaccine for West Nile virus in aged subjects
    • Beasley, D.W. Safety and immunogenicity of a chimeric vaccine for West Nile virus in aged subjects. Expert Rev. Vaccines 2011, 10, 601-604.
    • (2011) Expert Rev. Vaccines , vol.10 , pp. 601-604
    • Beasley, D.W.1
  • 29
    • 79851504695 scopus 로고    scopus 로고
    • Phase II, randomized, double-blind, placebo-controlled, multicenter study to investigate the immunogenicity and safety of a West Nile virus vaccine in healthy adults
    • Biedenbender, R.; Bevilacqua, J.; Gregg, A.M.; Watson, M.; Dayan, G. Phase II, randomized, double-blind, placebo-controlled, multicenter study to investigate the immunogenicity and safety of a West Nile virus vaccine in healthy adults. J. Infect. Dis. 2011, 203, 75-84.
    • (2011) J. Infect. Dis. , vol.203 , pp. 75-84
    • Biedenbender, R.1    Bevilacqua, J.2    Gregg, A.M.3    Watson, M.4    Dayan, G.5
  • 30
    • 84862870419 scopus 로고    scopus 로고
    • Measles vaccine expressing the secreted form of West Nile virus envelope glycoprotein induces protective immunity in squirrel monkeys, a new model of West Nile virus infection
    • Brandler, S.; Marianneau, P.; Loth, P.; Lacote, S.; Combredet, C.; Frenkiel, M.P.; Despres, P.; Contamin, H.; Tangy, F. Measles vaccine expressing the secreted form of West Nile virus envelope glycoprotein induces protective immunity in squirrel monkeys, a new model of West Nile virus infection. J. Infect. Dis. 2012, 206, 212-219.
    • (2012) J. Infect. Dis. , vol.206 , pp. 212-219
    • Brandler, S.1    Marianneau, P.2    Loth, P.3    Lacote, S.4    Combredet, C.5    Frenkiel, M.P.6    Despres, P.7    Contamin, H.8    Tangy, F.9
  • 32
    • 34948848718 scopus 로고    scopus 로고
    • Complex adenovirus-mediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses
    • Schepp-Berglind, J.; Luo, M.; Wang, D.; Wicker, J.A.; Raja, N.U.; Hoel, B.D.; Holman, D.H.; Barrett, A.D.; Dong, J.Y. Complex adenovirus-mediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses. Clin. Vaccine Immunol. 2007, 14, 1117-1126.
    • (2007) Clin. Vaccine Immunol. , vol.14 , pp. 1117-1126
    • Schepp-Berglind, J.1    Luo, M.2    Wang, D.3    Wicker, J.A.4    Raja, N.U.5    Hoel, B.D.6    Holman, D.H.7    Barrett, A.D.8    Dong, J.Y.9
  • 33
    • 33746271035 scopus 로고    scopus 로고
    • Production and characterization of vaccines based on flaviviruses defective in replication
    • Mason, P.W.; Shustov, A.V.; Frolov, I. Production and characterization of vaccines based on flaviviruses defective in replication. Virology 2006, 351, 432-443.
    • (2006) Virology , vol.351 , pp. 432-443
    • Mason, P.W.1    Shustov, A.V.2    Frolov, I.3
  • 34
    • 0035500283 scopus 로고    scopus 로고
    • Immunization of mice against West Nile virus with recombinant envelope protein
    • Wang, T.; Anderson, J.F.; Magnarelli, L.A.; Wong, S.J.; Koski, R.A.; Fikrig, E. Immunization of mice against West Nile virus with recombinant envelope protein. J. Immunol. 2001, 167, 5273-5277.
    • (2001) J. Immunol. , vol.167 , pp. 5273-5277
    • Wang, T.1    Anderson, J.F.2    Magnarelli, L.A.3    Wong, S.J.4    Koski, R.A.5    Fikrig, E.6
  • 35
    • 37449008696 scopus 로고    scopus 로고
    • Immunization with West Nile virus envelope domain III protects mice against lethal infection with homologous and heterologous virus
    • Martina, B.E.; Koraka, P.; van den Doel, P.; van Amerongen, G.; Rimmelzwaan, G.F.; Osterhaus, A.D. Immunization with West Nile virus envelope domain III protects mice against lethal infection with homologous and heterologous virus. Vaccine 2008, 26, 153-157.
    • (2008) Vaccine , vol.26 , pp. 153-157
    • Martina, B.E.1    Koraka, P.2    van den Doel, P.3    van Amerongen, G.4    Rimmelzwaan, G.F.5    Osterhaus, A.D.6
  • 36
    • 33847420827 scopus 로고    scopus 로고
    • Immunization of flavivirus West Nile recombinant envelope domain III protein induced specific immune response and protection against West Nile virus infection
    • Chu, J.H.; Chiang, C.C.; Ng, M.L. Immunization of flavivirus West Nile recombinant envelope domain III protein induced specific immune response and protection against West Nile virus infection. J. Immunol. 2007, 178, 2699-2705.
    • (2007) J. Immunol. , vol.178 , pp. 2699-2705
    • Chu, J.H.1    Chiang, C.C.2    Ng, M.L.3
  • 37
    • 79551707739 scopus 로고    scopus 로고
    • Immunodominance and functional activities of antibody responses to inactivated West Nile virus and recombinant subunit vaccines in mice
    • Zlatkovic, J.; Stiasny, K.; Heinz, F.X. Immunodominance and functional activities of antibody responses to inactivated West Nile virus and recombinant subunit vaccines in mice. J. Virol. 2011, 85, 1994-2003.
    • (2011) J. Virol. , vol.85 , pp. 1994-2003
    • Zlatkovic, J.1    Stiasny, K.2    Heinz, F.X.3
  • 43
    • 84885714579 scopus 로고    scopus 로고
    • Subcutaneous cholera toxin exposure induces potent CD103(+) dermal dendritic cell activation and migration
    • Apte, S.H.; Redmond, A.M.; Groves, P.L.; Schussek, S.; Pattinson, D.J.; Doolan, D.L. Subcutaneous cholera toxin exposure induces potent CD103(+) dermal dendritic cell activation and migration. Eur. J. Immunol. 2013, 43, 2707-2717.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 2707-2717
    • Apte, S.H.1    Redmond, A.M.2    Groves, P.L.3    Schussek, S.4    Pattinson, D.J.5    Doolan, D.L.6
  • 44
    • 0031296660 scopus 로고    scopus 로고
    • The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression
    • Cong, Y.; Weaver, C.T.; Elson, C.O. The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression. J. Immunol. 1997, 159, 5301-5308.
    • (1997) J. Immunol. , vol.159 , pp. 5301-5308
    • Cong, Y.1    Weaver, C.T.2    Elson, C.O.3
  • 45
    • 33644815406 scopus 로고    scopus 로고
    • Immunomodulation with enterotoxins for the generation of secretory immunity or tolerance: Applications for oral infections
    • Hajishengallis, G.; Arce, S.; Gockel, C.M.; Connell, T.D.; Russell, M.W. Immunomodulation with enterotoxins for the generation of secretory immunity or tolerance: Applications for oral infections. J. Dent. Res. 2005, 84, 1104-1116.
    • (2005) J. Dent. Res. , vol.84 , pp. 1104-1116
    • Hajishengallis, G.1    Arce, S.2    Gockel, C.M.3    Connell, T.D.4    Russell, M.W.5
  • 46
    • 0037378940 scopus 로고    scopus 로고
    • Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development
    • Eriksson, K.; Fredriksson, M.; Nordstrom, I.; Holmgren, J. Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development. Infect. Immun. 2003, 71, 1740-1747.
    • (2003) Infect. Immun. , vol.71 , pp. 1740-1747
    • Eriksson, K.1    Fredriksson, M.2    Nordstrom, I.3    Holmgren, J.4
  • 47
    • 34249866843 scopus 로고    scopus 로고
    • Induction of cell signaling events by the cholera toxin B subunit in antigen-presenting cells
    • Schnitzler, A.C.; Burke, J.M.; Wetzler, L.M. Induction of cell signaling events by the cholera toxin B subunit in antigen-presenting cells. Infect. Immun. 2007, 75, 3150-3159.
    • (2007) Infect. Immun. , vol.75 , pp. 3150-3159
    • Schnitzler, A.C.1    Burke, J.M.2    Wetzler, L.M.3
  • 48
    • 0028244301 scopus 로고
    • Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant
    • Holmgren, J.; Czerkinsky, C.; Lycke, N.; Svennerholm, A.M. Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant. Am. J. Trop. Med. Hyg. 1994, 50, 42-54.
    • (1994) Am. J. Trop. Med. Hyg. , vol.50 , pp. 42-54
    • Holmgren, J.1    Czerkinsky, C.2    Lycke, N.3    Svennerholm, A.M.4
  • 49
    • 77955005217 scopus 로고    scopus 로고
    • Cholera toxin B subunit modulation of mucosal vaccines for infectious and autoimmune diseases
    • Langridge, W.; Denes, B.; Fodor, I. Cholera toxin B subunit modulation of mucosal vaccines for infectious and autoimmune diseases. Curr. Opin. Investig. Drugs 2010, 11, 919-928.
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , pp. 919-928
    • Langridge, W.1    Denes, B.2    Fodor, I.3
  • 50
    • 0034873558 scopus 로고    scopus 로고
    • Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells
    • George-Chandy, A.; Eriksson, K.; Lebens, M.; Nordstrom, I.; Schon, E.; Holmgren, J. Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells. Infect. Immun. 2001, 69, 5716-5725.
    • (2001) Infect. Immun. , vol.69 , pp. 5716-5725
    • George-Chandy, A.1    Eriksson, K.2    Lebens, M.3    Nordstrom, I.4    Schon, E.5    Holmgren, J.6
  • 51
    • 0026489949 scopus 로고
    • Fusion proteins containing the A2 domain of cholera toxin assemble with B polypeptides of cholera toxin to form immunoreactive and functional holotoxin-like chimeras
    • Jobling, M.G.; Holmes, R.K. Fusion proteins containing the A2 domain of cholera toxin assemble with B polypeptides of cholera toxin to form immunoreactive and functional holotoxin-like chimeras. Infect. Immun. 1992, 60, 4915-4924.
    • (1992) Infect. Immun. , vol.60 , pp. 4915-4924
    • Jobling, M.G.1    Holmes, R.K.2
  • 52
    • 0029036648 scopus 로고
    • Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B subunits
    • Hajishengallis, G.; Hollingshead, S.K.; Koga, T.; Russell, M.W. Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B subunits. J. Immunol. 1995, 154, 4322-4332.
    • (1995) J. Immunol. , vol.154 , pp. 4322-4332
    • Hajishengallis, G.1    Hollingshead, S.K.2    Koga, T.3    Russell, M.W.4
  • 53
    • 28244463329 scopus 로고    scopus 로고
    • Induction and recall of immune memory by mucosal immunization with a non-toxic recombinant enterotoxin-based chimeric protein
    • Gockel, C.M.; Russell, M.W. Induction and recall of immune memory by mucosal immunization with a non-toxic recombinant enterotoxin-based chimeric protein. Immunology 2005, 116, 477-486.
    • (2005) Immunology , vol.116 , pp. 477-486
    • Gockel, C.M.1    Russell, M.W.2
  • 54
    • 0030052078 scopus 로고    scopus 로고
    • Persistence of serum and salivary antibody responses after oral immunization with a bacterial protein antigen genetically linked to the A2/B subunits of cholera toxin
    • Hajishengallis, G.; Michalek, S.M.; Russell, M.W. Persistence of serum and salivary antibody responses after oral immunization with a bacterial protein antigen genetically linked to the A2/B subunits of cholera toxin. Infect. Immun. 1996, 64, 665-667.
    • (1996) Infect. Immun. , vol.64 , pp. 665-667
    • Hajishengallis, G.1    Michalek, S.M.2    Russell, M.W.3
  • 55
    • 0037381690 scopus 로고    scopus 로고
    • Mucosal immunization with a genetically engineered pertussis toxin S1 fragment-cholera toxin subunit B chimeric protein
    • Lee, S.F.; Halperin, S.A.; Salloum, D.F.; MacMillan, A.; Morris, A. Mucosal immunization with a genetically engineered pertussis toxin S1 fragment-cholera toxin subunit B chimeric protein. Infect. Immun. 2003, 71, 2272-2275.
    • (2003) Infect. Immun. , vol.71 , pp. 2272-2275
    • Lee, S.F.1    Halperin, S.A.2    Salloum, D.F.3    McMillan, A.4    Morris, A.5
  • 56
    • 80052447250 scopus 로고    scopus 로고
    • Mucosal immunization with a Staphylococcus aureus IsdA-cholera toxin A2/B chimera induces antigen-specific Th2-type responses in mice
    • Arlian, B.M.; Tinker, J.K. Mucosal immunization with a Staphylococcus aureus IsdA-cholera toxin A2/B chimera induces antigen-specific Th2-type responses in mice. Clin. Vaccine Immunol. 2011, 18, 1543-1551.
    • (2011) Clin. Vaccine Immunol. , vol.18 , pp. 1543-1551
    • Arlian, B.M.1    Tinker, J.K.2
  • 57
    • 19744375740 scopus 로고    scopus 로고
    • Characterization of fluorescent chimeras of cholera toxin and Escherichia coli heat-labile enterotoxins produced by use of the twin arginine translocation system
    • Tinker, J.K.; Erbe, J.L.; Holmes, R.K. Characterization of fluorescent chimeras of cholera toxin and Escherichia coli heat-labile enterotoxins produced by use of the twin arginine translocation system. Infect. Immun. 2005, 73, 3627-3635.
    • (2005) Infect. Immun. , vol.73 , pp. 3627-3635
    • Tinker, J.K.1    Erbe, J.L.2    Holmes, R.K.3
  • 58
    • 77957862166 scopus 로고    scopus 로고
    • Purification and characterization of Yersinia enterocolitica and Yersinia pestis LcrV-cholera toxin A(2)/B chimeras
    • Tinker, J.K.; Davis, C.T.; Arlian, B.M. Purification and characterization of Yersinia enterocolitica and Yersinia pestis LcrV-cholera toxin A(2)/B chimeras. Protein Expr. Purif. 2010, 74, 16-23.
    • (2010) Protein Expr. Purif. , vol.74 , pp. 16-23
    • Tinker, J.K.1    Davis, C.T.2    Arlian, B.M.3
  • 59
    • 0029898287 scopus 로고    scopus 로고
    • Transport of an external Lys-Asp-Glu-Leu (KDEL) protein from the plasma membrane to the endoplasmic reticulum: Studies with cholera toxin in Vero cells
    • Majoul, I.V.; Bastiaens, P.I.; Soling, H.D. Transport of an external Lys-Asp-Glu-Leu (KDEL) protein from the plasma membrane to the endoplasmic reticulum: studies with cholera toxin in Vero cells. J. Cell. Biol. 1996, 133, 777-789.
    • (1996) J. Cell. Biol. , vol.133 , pp. 777-789
    • Majoul, I.V.1    Bastiaens, P.I.2    Soling, H.D.3
  • 61
    • 44849126376 scopus 로고    scopus 로고
    • Cholera toxin E. coli heat-labile toxin, and non-toxic derivatives induce dendritic cell migration into the follicle-associated epithelium of Peyer's patches
    • Anosova, N.G.; Chabot, S.; Shreedhar, V.; Borawski, J.A.; Dickinson, B.L.; Neutra, M.R. Cholera toxin, E. coli heat-labile toxin, and non-toxic derivatives induce dendritic cell migration into the follicle-associated epithelium of Peyer's patches. Mucosal Immunol. 2008, 1, 59-67.
    • (2008) Mucosal Immunol. , vol.1 , pp. 59-67
    • Anosova, N.G.1    Chabot, S.2    Shreedhar, V.3    Borawski, J.A.4    Dickinson, B.L.5    Neutra, M.R.6
  • 63
    • 0029741379 scopus 로고    scopus 로고
    • Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin
    • Bastiaens, P.I.; Majoul, I.V.; Verveer, P.J.; Soling, H.D.; Jovin, T.M. Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin. Embo J. 1996, 15, 4246-4253.
    • (1996) Embo J. , vol.15 , pp. 4246-4253
    • Bastiaens, P.I.1    Majoul, I.V.2    Verveer, P.J.3    Soling, H.D.4    Jovin, T.M.5
  • 64
    • 9244255836 scopus 로고    scopus 로고
    • Use of translational fusion of the MrpH fimbrial adhesin-binding domain with the cholera toxin A2 domain, coexpressed with the cholera toxin B subunit, as an intranasal vaccine to prevent experimental urinary tract infection by Proteus mirabilis
    • Li, X.; Erbe, J.L.; Lockatell, C.V.; Johnson, D.E.; Jobling, M.G.; Holmes, R.K.; Mobley, H.L. Use of translational fusion of the MrpH fimbrial adhesin-binding domain with the cholera toxin A2 domain, coexpressed with the cholera toxin B subunit, as an intranasal vaccine to prevent experimental urinary tract infection by Proteus mirabilis. Infect. Immun. 2004, 72, 7306-7310.
    • (2004) Infect. Immun. , vol.72 , pp. 7306-7310
    • Li, X.1    Erbe, J.L.2    Lockatell, C.V.3    Johnson, D.E.4    Jobling, M.G.5    Holmes, R.K.6    Mobley, H.L.7
  • 65
    • 0031908219 scopus 로고    scopus 로고
    • Mucosal immunogenicity of a holotoxin-like molecule containing the serine-rich Entamoeba histolytica protein (SREHP) fused to the A2 domain of cholera toxin
    • Sultan, F.; Jin, L.L.; Jobling, M.G.; Holmes, R.K.; Stanley, S.L., Jr. Mucosal immunogenicity of a holotoxin-like molecule containing the serine-rich Entamoeba histolytica protein (SREHP) fused to the A2 domain of cholera toxin. Infect. Immun. 1998, 66, 462-468.
    • (1998) Infect. Immun. , vol.66 , pp. 462-468
    • Sultan, F.1    Jin, L.L.2    Jobling, M.G.3    Holmes, R.K.4    Stanley Jr., S.L.5
  • 69
    • 46349102408 scopus 로고    scopus 로고
    • Multi-epitope DNA vaccine linked to the A2/B subunit of cholera toxin protect mice against Toxoplasma gondii
    • Cong, H.; Gu, Q.M.; Yin, H.E.; Wang, J.W.; Zhao, Q.L.; Zhou, H.Y.; Li, Y.; Zhang, J.Q. Multi-epitope DNA vaccine linked to the A2/B subunit of cholera toxin protect mice against Toxoplasma gondii. Vaccine 2008, 26, 3913-3921.
    • (2008) Vaccine , vol.26 , pp. 3913-3921
    • Cong, H.1    Gu, Q.M.2    Yin, H.E.3    Wang, J.W.4    Zhao, Q.L.5    Zhou, H.Y.6    Li, Y.7    Zhang, J.Q.8
  • 70
    • 60049093592 scopus 로고    scopus 로고
    • A Vibrio cholerae ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin
    • Ekong, E.E.; Okenu, D.N.; Mania-Pramanik, J.; He, Q.; Igietseme, J.U.; Ananaba, G.A.; Lyn, D.; Black, C.; Eko, F.O. A Vibrio cholerae ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin. FEMS Immunol. Med. Microbiol. 2009, 55, 280-291.
    • (2009) FEMS Immunol. Med. Microbiol. , vol.55 , pp. 280-291
    • Ekong, E.E.1    Okenu, D.N.2    Mania-Pramanik, J.3    He, Q.4    Igietseme, J.U.5    Ananaba, G.A.6    Lyn, D.7    Black, C.8    Eko, F.O.9
  • 71
    • 19944405462 scopus 로고    scopus 로고
    • Complement activation is required for induction of a protective antibody response against West Nile virus infection
    • Mehlhop, E.; Whitby, K.; Oliphant, T.; Marri, A.; Engle, M.; Diamond, M.S. Complement activation is required for induction of a protective antibody response against West Nile virus infection. J. Virol. 2005, 79, 7466-7477.
    • (2005) J. Virol. , vol.79 , pp. 7466-7477
    • Mehlhop, E.1    Whitby, K.2    Oliphant, T.3    Marri, A.4    Engle, M.5    Diamond, M.S.6
  • 74
    • 33644973069 scopus 로고    scopus 로고
    • Quantifying the specific binding between West Nile virus envelope domain III protein and the cellular receptor alphaVbeta3 integrin
    • Lee, J.W.; Chu, J.J.; Ng, M.L. Quantifying the specific binding between West Nile virus envelope domain III protein and the cellular receptor alphaVbeta3 integrin. J. Biol. Chem. 2006, 281, 1352-1360.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1352-1360
    • Lee, J.W.1    Chu, J.J.2    Ng, M.L.3
  • 75
    • 11144227268 scopus 로고    scopus 로고
    • Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells
    • Chu, J.J.; Ng, M.L. Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells. J. Biol. Chem. 2004, 279, 54533-54541.
    • (2004) J. Biol. Chem. , vol.279 , pp. 54533-54541
    • Chu, J.J.1    Ng, M.L.2
  • 77
    • 43949122204 scopus 로고    scopus 로고
    • West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of alphavbeta3 integrin
    • Medigeshi, G.R.; Hirsch, A.J.; Streblow, D.N.; Nikolich-Zugich, J.; Nelson, J.A. West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of alphavbeta3 integrin. J. Virol. 2008, 82, 5212-5219.
    • (2008) J. Virol. , vol.82 , pp. 5212-5219
    • Medigeshi, G.R.1    Hirsch, A.J.2    Streblow, D.N.3    Nikolich-Zugich, J.4    Nelson, J.A.5
  • 79
    • 33646951039 scopus 로고    scopus 로고
    • Centrifugation enhances integrin-mediated transduction of dendritic cells by conventional and RGD-modified adenoviral vectors
    • Harui, A.; Roth, M.D.; Sanghvi, M.; Vira, D.; Mizuguchi, H.; Basak, S.K. Centrifugation enhances integrin-mediated transduction of dendritic cells by conventional and RGD-modified adenoviral vectors. J. Immunol. Methods 2006, 312, 94-104.
    • (2006) J. Immunol. Methods , vol.312 , pp. 94-104
    • Harui, A.1    Roth, M.D.2    Sanghvi, M.3    Vira, D.4    Mizuguchi, H.5    Basak, S.K.6
  • 80
    • 84857871177 scopus 로고    scopus 로고
    • AlphaVbeta3-integrin relocalizes nectin1 and routes herpes simplex virus to lipid rafts
    • Gianni, T.; Campadelli-Fiume, G. AlphaVbeta3-integrin relocalizes nectin1 and routes herpes simplex virus to lipid rafts. J. Virol. 2012, 86, 2850-2855.
    • (2012) J. Virol. , vol.86 , pp. 2850-2855
    • Gianni, T.1    Campadelli-Fiume, G.2
  • 81
    • 78650663541 scopus 로고    scopus 로고
    • AlphaVbeta3-integrin routes herpes simplex virus to an entry pathway dependent on cholesterol-rich lipid rafts and dynamin2
    • Gianni, T.; Gatta, V.; Campadelli-Fiume, G. AlphaVbeta3-integrin routes herpes simplex virus to an entry pathway dependent on cholesterol-rich lipid rafts and dynamin2. Proc. Natl. Acad. Sci. USA 2010, 107, 22260-22265.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 22260-22265
    • Gianni, T.1    Gatta, V.2    Campadelli-Fiume, G.3
  • 82
    • 79953005700 scopus 로고    scopus 로고
    • Cholera toxin-A foe & a friend
    • Sanchez, J.; Holmgren, J. Cholera toxin-A foe & a friend. Indian J. Med. Res. 2011, 133, 153-163.
    • (2011) Indian J. Med. Res. , vol.133 , pp. 153-163
    • Sanchez, J.1    Holmgren, J.2
  • 83
    • 72349096793 scopus 로고    scopus 로고
    • Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit
    • Sun, J.B.; Czerkinsky, C.; Holmgren, J. Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit. Scand. J. Immunol. 2010, 71, 1-11.
    • (2010) Scand. J. Immunol. , vol.71 , pp. 1-11
    • Sun, J.B.1    Czerkinsky, C.2    Holmgren, J.3
  • 84
    • 0035825573 scopus 로고    scopus 로고
    • Effects of intranasal administration of cholera toxin (or Escherichia coli heat-labile enterotoxin) B subunits supplemented with a trace amount of the holotoxin on the brain
    • Hagiwara, Y.; Iwasaki, T.; Asanuma, H.; Sato, Y.; Sata, T.; Aizawa, C.; Kurata, T.; Tamura, S. Effects of intranasal administration of cholera toxin (or Escherichia coli heat-labile enterotoxin) B subunits supplemented with a trace amount of the holotoxin on the brain. Vaccine 2001, 19, 1652-1660.
    • (2001) Vaccine , vol.19 , pp. 1652-1660
    • Hagiwara, Y.1    Iwasaki, T.2    Asanuma, H.3    Sato, Y.4    Sata, T.5    Aizawa, C.6    Kurata, T.7    Tamura, S.8
  • 85
    • 0034327167 scopus 로고    scopus 로고
    • Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues
    • Van Ginkel, F.W.; Jackson, R.J.; Yuki, Y.; McGhee, J.R. Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues. J. Immunol. 2000, 165, 4778-4782.
    • (2000) J. Immunol. , vol.165 , pp. 4778-4782
    • Van Ginkel, F.W.1    Jackson, R.J.2    Yuki, Y.3    McGhee, J.R.4
  • 87
    • 70349621646 scopus 로고    scopus 로고
    • Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin
    • Lewis, D.J.; Huo, Z.; Barnett, S.; Kromann, I.; Giemza, R.; Galiza, E.; Woodrow, M.; Thierry-Carstensen, B.; Andersen, P.; Novicki, D.; et al. Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin. PLoS ONE 2009, 4, e6999.
    • (2009) PLoS ONE , vol.4
    • Lewis, D.J.1    Huo, Z.2    Barnett, S.3    Kromann, I.4    Giemza, R.5    Galiza, E.6    Woodrow, M.7    Thierry-Carstensen, B.8    Andersen, P.9    Novicki, D.10
  • 88
    • 1342268100 scopus 로고    scopus 로고
    • Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland
    • Mutsch, M.; Zhou, W.; Rhodes, P.; Bopp, M.; Chen, R.T.; Linder, T.; Spyr, C.; Steffen, R. Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland. N. Engl. J. Med. 2004, 350, 896-903.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 896-903
    • Mutsch, M.1    Zhou, W.2    Rhodes, P.3    Bopp, M.4    Chen, R.T.5    Linder, T.6    Spyr, C.7    Steffen, R.8
  • 90
    • 85158991207 scopus 로고    scopus 로고
    • Elsievier: Philadelphia, PA, USA
    • Tacket, C.O.; Sack, D.A. Cholera Vaccines; Elsievier: Philadelphia, PA, USA, 2008; Volume 5, pp. 127-138.
    • (2008) Cholera Vaccines , vol.5 , pp. 127-138
    • Tacket, C.O.1    Sack, D.A.2
  • 92
    • 0037309156 scopus 로고    scopus 로고
    • Transcutaneous immunization with cholera toxin B subunit adjuvant suppresses IgE antibody responses via selective induction of Th1 immune responses
    • Anjuere, F.; George-Chandy, A.; Audant, F.; Rousseau, D.; Holmgren, J.; Czerkinsky, C. Transcutaneous immunization with cholera toxin B subunit adjuvant suppresses IgE antibody responses via selective induction of Th1 immune responses. J. Immunol. 2003, 170, 1586-1592.
    • (2003) J. Immunol. , vol.170 , pp. 1586-1592
    • Anjuere, F.1    George-Chandy, A.2    Audant, F.3    Rousseau, D.4    Holmgren, J.5    Czerkinsky, C.6
  • 93
    • 0842326199 scopus 로고    scopus 로고
    • Transcutaneous immunization with combined cholera toxin and CpG adjuvant protects against Chlamydia muridarum genital tract infection
    • Berry, L.J.; Hickey, D.K.; Skelding, K.A.; Bao, S.; Rendina, A.M.; Hansbro, P.M.; Gockel, C.M.; Beagley, K.W. Transcutaneous immunization with combined cholera toxin and CpG adjuvant protects against Chlamydia muridarum genital tract infection. Infect. Immun. 2004, 72, 1019-1028.
    • (2004) Infect. Immun. , vol.72 , pp. 1019-1028
    • Berry, L.J.1    Hickey, D.K.2    Skelding, K.A.3    Bao, S.4    Rendina, A.M.5    Hansbro, P.M.6    Gockel, C.M.7    Beagley, K.W.8
  • 94
    • 0024565465 scopus 로고
    • Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues
    • Czerkinsky, C.; Russell, M.W.; Lycke, N.; Lindblad, M.; Holmgren, J. Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. Infect. Immun. 1989, 57, 1072-1077.
    • (1989) Infect. Immun. , vol.57 , pp. 1072-1077
    • Czerkinsky, C.1    Russell, M.W.2    Lycke, N.3    Lindblad, M.4    Holmgren, J.5
  • 95
    • 77955049326 scopus 로고    scopus 로고
    • Sublingual immunization with an HIV subunit vaccine induces antibodies and cytotoxic T cells in the mouse female genital tract
    • Hervouet, C.; Luci, C.; Cuburu, N.; Cremel, M.; Bekri, S.; Vimeux, L.; Maranon, C.; Czerkinsky, C.; Hosmalin, A.; Anjuere, F. Sublingual immunization with an HIV subunit vaccine induces antibodies and cytotoxic T cells in the mouse female genital tract. Vaccine 2010, 28, 5582-5590.
    • (2010) Vaccine , vol.28 , pp. 5582-5590
    • Hervouet, C.1    Luci, C.2    Cuburu, N.3    Cremel, M.4    Bekri, S.5    Vimeux, L.6    Maranon, C.7    Czerkinsky, C.8    Hosmalin, A.9    Anjuere, F.10
  • 96
    • 79954535010 scopus 로고    scopus 로고
    • Characterization of a mutant Escherichia coli heat-labile toxin, LT(R192G/L211A), as a safe and effective oral adjuvant
    • Norton, E.B.; Lawson, L.B.; Freytag, L.C.; Clements, J.D. Characterization of a mutant Escherichia coli heat-labile toxin, LT(R192G/L211A), as a safe and effective oral adjuvant. Clin. Vaccine Immunol. 2011, 18, 546-551.
    • (2011) Clin. Vaccine Immunol. , vol.18 , pp. 546-551
    • Norton, E.B.1    Lawson, L.B.2    Freytag, L.C.3    Clements, J.D.4
  • 97
    • 84879464595 scopus 로고    scopus 로고
    • Transcutaneous immunization of healthy volunteers with an attenuated Listeria monocytogenes vaccine strain and cholera toxin adjuvant
    • Eypper, E.H.; Johnson, P.V.; Purro, E.I.; Hohmann, E.L. Transcutaneous immunization of healthy volunteers with an attenuated Listeria monocytogenes vaccine strain and cholera toxin adjuvant. Vaccine 2013, 31, 3257-3261.
    • (2013) Vaccine , vol.31 , pp. 3257-3261
    • Eypper, E.H.1    Johnson, P.V.2    Purro, E.I.3    Hohmann, E.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.