B-type suppression: A role played by "regulatory B cells" or "regulatory plasma cells"?

European Journal of Immunology

Volumn 44, Issue 5, 2014, Pages 1251-1257

  Ries, Stefanie ^a   Hilgenberg, Ellen ^a   Lampropoulou, Vicky ^a   Shen, Ping ^a   Dang, Van Duc ^a   Wilantri, Siska ^a   Sakwa, Imme ^a   Fillatreau, Simon ^a  

^a DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

Autoimmune disease; B cells; Infection; Interleukin 10; Plasma cells; Regulation

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD19 ANTIGEN; CD40 ANTIGEN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 10; INTERLEUKIN 35; INTERLEUKIN 6; KIDNEY INJURY MOLECULE 1; SYNDECAN 1;

ANTIBODY PRODUCTION; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMORAL IMMUNE DEFICIENCY; HUMORAL IMMUNITY; IMMUNOPATHOGENESIS; IMMUNOPHENOTYPING; IN VIVO STUDY; MOLECULAR MECHANICS; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; REGULATORY PLASMA CELL; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE SUBPOPULATION;

AUTOIMMUNE DISEASE; B CELLS; INFECTION; INTERLEUKIN-10; PLASMA CELLS; REGULATION;

ANIMALS; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES, REGULATORY; HUMANS; IMMUNITY, HUMORAL; IMMUNITY, INNATE; INTERLEUKIN-10; MICE; MULTIPLE SCLEROSIS; PLASMA CELLS;

EID: 84899570518     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343683     Document Type: Review

References (59)

1. Mizoguchi, A., Mizoguchi, E., Takedatsu, H., Blumberg, R. S. and Bhan, A. K., Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 2002. 16: 219-230.
2. Fillatreau, S., Sweenie, C. H., McGeachy, M. J., Gray, D. and Anderton, S. M., B cells regulate autoimmunity by provision of IL-10. Nat. Immunol. 2002. 3: 944-950.
3. Mauri, C., Gray, D., Mushtaq, N. and Londei, M., Prevention of arthritis by interleukin 10-producing B cells. J. Exp. Med. 2003. 197: 489-501.
4. Mombaerts, P., Mizoguchi, E., Grusby, M. J., Glimcher, L. H., Bhan, A. K. and Tonegawa, S., Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell 1993. 75: 274-282.
5. Mizoguchi, A., Mizoguchi, E., Chiba, C., Spiekermann, G. M., Tonegawa, S., Nagler-Anderson, C. and Bhan, A. K., Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease. J. Exp. Med. 1996. 183: 847-856.
6. Mizoguchi, A., Mizoguchi, E. and Bhan, A. K., The critical role of interleukin 4 but not interferon gamma in the pathogenesis of colitis in T-cell receptor alpha mutant mice. Gastroenterology 1999. 116: 320-326.
7. Mizoguchi, A., Mizoguchi, E., Smith, R. N., Preffer, F. I. and Bhan, A. K., Suppressive role of B cells in chronic colitis of T cell receptor alpha mutant mice. J. Exp. Med. 1997. 186: 1749-1756.
8. Hoehlig, K., Shen, P., Lampropoulou, V., Roch, T., Malissen, B., O'Connor, R., Ries, S. et al., Activation of CD4(+) Foxp3(+) regulatory T cells proceeds normally in the absence of B cells during EAE. Eur. J. Immunol. 2012. 42: 1164-1173.
9. Barr, T. A., Shen, P., Brown, S., Lampropoulou, V., Roch, T., Lawrie, S., Fan, B. et al., B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6-producing B cells. J. Exp. Med. 2012. 209: 1001-1010.
10. Ding, Q., Yeung, M., Camirand, G., Zeng, Q., Akiba, H., Yagita, H., Chalasani, G. et al., Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J. Clin. Invest. 2011. 121: 3645-3656.
11. Neves, P., Lampropoulou, V., Calderon-Gomez, E., Roch, T., Stervbo, U., Shen, P., Kuhl, A. A. et al., Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection. Immunity 2010. 33: 777-790.
12. Horikawa, M., Weimer, E. T., DiLillo, D. J., Venturi, G. M., Spolski, R., Leonard, W. J., Heise, M. T. and Tedder, T. F., Regulatory B cell (B10 cell) expansion during Listeria infection governs innate and cellular immune responses in mice. J. Immunol. 2013. 190: 1158-1168.
13. Hussaarts, L., van der Vlugt, L. E., Yazdanbakhsh, M. and Smits, H. H., Regulatory B-cell induction by helminths: implications for allergic disease. J. Allergy Clin. Immunol. 2011. 128: 733-739.
14. Offner, H. and Hurn, P. D., A novel hypothesis: regulatory B lymphocytes shape outcome from experimental stroke. Transl. Stroke Res. 2012. 3: 324-330.
15. Matsushita, T., Fujimoto, M., Hasegawa, M., Komura, K., Takehara, K., Tedder, T. F. and Sato, S., Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response. Am. J. Pathol. 2006. 168: 812-821.
16. Yanaba, K., Bouaziz, J. D., Haas, K. M., Poe, J. C., Fujimoto, M. and Tedder, T. F., A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity 2008. 28: 639-650.
17. Grewal, I. S., Foellmer, H. G., Grewal, K. D., Xu, J., Hardardottir, F., Baron, J. L., Janeway, C. A., Jr. and Flavell, R. A., Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis. Science 1996. 273: 1864-1867.
18. Lougaris, V., Badolato, R., Ferrari, S. and Plebani, A., Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features. Immunol. Rev. 2005. 203: 48-66.
19. Lampropoulou, V., Hoehlig, K., Roch, T., Neves, P., Calderon Gomez, E., Sweenie, C. H., Hao, Y. et al., TLR-activated B cells suppress T cell-mediated autoimmunity. J. Immunol. 2008. 180: 4763-4773.
20. Krieg, A. M., Yi, A. K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A. and Klinman, D. M., CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995. 374: 546-549.
21. Lampropoulou, V., Calderon-Gomez, E., Roch, T., Neves, P., Shen, P., Stervbo, U., Boudinot, P. et al., Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll-like receptors in immunity. Immunol. Rev. 2010. 233: 146-161.
22. Matsumoto, M., Fujii, Y., Baba, A., Hikida, M., Kurosaki, T. and Baba, Y., The calcium sensors STIM1 and STIM2 control B cell regulatory function through interleukin-10 production. Immunity 2011. 34: 703-714.
23. Lechouane, F., Bonaud, A., Delpy, L., Casola, S., Oruc, Z., Chemin, G., Cogne, M. and Sirac, C., B-cell receptor signal strength influences terminal differentiation. Eur. J. Immunol. 2013. 43: 619-628.
24. Yoshizaki, A., Miyagaki, T., DiLillo, D. J., Matsushita, T., Horikawa, M., Kountikov, E. I., Spolski, R. et al., Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. Nature 2012. 491: 264-268.
25. Kallies, A., Hasbold, J., Fairfax, K., Pridans, C., Emslie, D., McKenzie, B. S., Lew, A. M. et al., Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. Immunity 2007. 26: 555-566.
26. Ozaki, K., Spolski, R., Ettinger, R., Kim, H. P., Wang, G., Qi, C. F., Hwu, P. et al., Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J. Immunol. 2004. 173: 5361-5371.
27. Ettinger, R., Sims, G. P., Fairhurst, A. M., Robbins, R., da Silva, Y. S., Spolski, R., Leonard, W. J. and Lipsky, P. E., IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J. Immunol. 2005. 175: 7867-7879.
28. Yoshida, T., Mei, H., Dorner, T., Hiepe, F., Radbruch, A., Fillatreau, S. and Hoyer, B. F., Memory B and memory plasma cells. Immunol. Rev. 2010. 237: 117-139.
29. Yanaba, K., Bouaziz, J. D., Matsushita, T., Tsubata, T. and Tedder, T. F., The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J. Immunol. 2009. 182: 7459-7472.
30. Bouaziz, J. D., Yanaba, K. and Tedder, T. F., Regulatory B cells as inhibitors of immune responses and inflammation. Immunol. Rev. 2008. 224: 201-214.
31. Shen, P., Roch, T., Lampropoulou, V., O'Connor, R. A., Stervbo, U., Hilgenberg, E., Ries, S. et al., IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature 2014. 507: 366-370.
32. Calderon-Gomez, E., Lampropoulou, V., Shen, P., Neves, P., Roch, T., Stervbo, U., Rutz, S., Kuhl, A. A. et al., Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis. Eur. J. Immunol. 2011. 41: 1696-1708.
33. Sun, C. M., Deriaud, E., Leclerc, C. and Lo-Man, R., Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs. Immunity 2005. 22: 467-477.
34. O'Garra, A., Chang, R., Go, N., Hastings, R., Haughton, G. and Howard, M., Ly-1 B (B-1) cells are the main source of B cell-derived interleukin 10. Eur. J. Immunol. 1992. 22: 711-717.
35. Evans, J. G., Chavez-Rueda, K. A., Eddaoudi, A., Meyer-Bahlburg, A., Rawlings, D. J., Ehrenstein, M. R. and Mauri, C., Novel suppressive function of transitional 2 B cells in experimental arthritis. J. Immunol. 2007. 178: 7868-7878.
36. Martin, F. and Kearney, J. F., B1 cells: similarities and differences with other B cell subsets. Curr. Opin. Immunol. 2001. 13: 195-201.
37. Ueda, Y., Liao, D., Yang, K., Patel, A. and Kelsoe, G., T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. J. Immunol. 2007. 178: 3593-3601.
38. Capolunghi, F., Cascioli, S., Giorda, E., Rosado, M. M., Plebani, A., Auriti, C., Seganti, G. et al., CpG drives human transitional B cells to terminal differentiation and production of natural antibodies. J. Immunol. 2008. 180: 800-808.
39. Forza, G., Buja, A., Tognazzo, F., Vinelli, A., Baldo, V. and Amadori, A., Smoking in early and mid-adolescence. J. Dev. Behav. Pediatr. 2012. 33: 449-455.
40. Freeman, G. J., Casasnovas, J. M., Umetsu, D. T. and DeKruyff, R. H., TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol. Rev. 2010. 235: 172-189.
41. Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J. J., Bratton, D. L. and Henson, P. M., Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 1992. 148: 2207-2216.
42. Gray, M., Miles, K., Salter, D., Gray, D. and Savill, J., Apoptotic cells protect mice from autoimmune inflammation by the induction of regulatory B cells. Proc. Natl. Acad. Sci. USA 2007. 104: 14080-14085.
43. Puga, I., Cols, M., Barra, C. M., He, B., Cassis, L., Gentile, M., Comerma, L. et al., B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat. Immunol. 2012. 13: 170-180.
44. Rousset, F., Garcia, E., Defrance, T., Peronne, C., Vezzio, N., Hsu, D. H., Kastelein, R. et al., Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad Sci. USA 1992. 89: 1890-1893.
45. Teichmann, L. L., Kashgarian, M., Weaver, C. T., Roers, A., Muller, W. and Shlomchik, M. J., B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice. J. Immunol. 2012. 188: 678-685.
46. Chun, H. Y., Chung, J. W., Kim, H. A., Yun, J. M., Jeon, J. Y., Ye, Y. M., Kim, S. H. et al., Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus. J. Clin. Immunol. 2007. 27: 461-466.
47. Emilie, D., [Interleukin 10 in disseminated lupus erythematosus]. J. Soc. Biol. 2002. 196: 19-21.
48. Llorente, L., Richaud-Patin, Y., Garcia-Padilla, C., Claret, E., Jakez-Ocampo, J., Cardiel, M. H., Alcocer-Varela, J. et al., Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus. Arthritis Rheum. 2000. 43: 1790-1800.
49. Maseda, D., Smith, S. H., DiLillo, D. J., Bryant, J. M., Candando, K. M., Weaver, C. T. and Tedder, T. F., Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. J. Immunol. 2012. 188: 1036-1048.
50. Rauch, P. J., Chudnovskiy, A., Robbins, C. S., Weber, G. F., Etzrodt, M., Hilgendorf, I., Tiglao, E. et al., Innate response activator B cells protect against microbial sepsis. Science 2012. 335: 597-601.
51. Fritz, J. H., Rojas, O. L., Simard, N., McCarthy, D. D., Hapfelmeier, S., Rubino, S., Robertson, S. J. et al., Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature 2012. 481: 199-203.
52. Duddy, M., Niino, M., Adatia, F., Hebert, S., Freedman, M., Atkins, H., Kim, H. J. and Bar-Or, A., Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis. J. Immunol. 2007. 178: 6092-6099.
53. Jagannathan, M., McDonnell, M., Liang, Y., Hasturk, H., Hetzel, J., Rubin, D., Kantarci, A. et al., Toll-like receptors regulate B cell cytokine production in patients with diabetes. Diabetologia 2010. 53: 1461-1471.
54. Goetz, M., Atreya, R., Ghalibafian, M., Galle, P. R. and Neurath, M. F., Exacerbation of ulcerative colitis after rituximab salvage therapy. Inflamm. Bowel. Dis. 2007. 13: 1365-1368.
55. Correale, J., Farez, M. and Razzitte, G., Helminth infections associated with multiple sclerosis induce regulatory B cells. Ann. Neurol. 2008. 64: 187-199.
56. Correale, J. and Farez, M., Association between parasite infection and immune responses in multiple sclerosis. Ann. Neurol. 2007. 61: 97-108.
57. Balazs, M., Martin, F., Zhou, T. and Kearney, J., Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 2002. 17: 341-352.
58. O'Connor, B. P., Raman, V. S., Erickson, L. D., Cook, W. J., Weaver, L. K., Ahonen, C., Lin, L. L. et al., BCMA is essential for the survival of long-lived bone marrow plasma cells. J. Exp. Med. 2004. 199: 91-98.
59. Hartung, H. P. and Kieseier, B. C., Atacicept: targeting B cells in multiple sclerosis. Ther. Adv. Neurol. Disord. 2010. 3: 205-216.