A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

Immunity

Volumn 28, Issue 5, 2008, Pages 639-650

  Yanaba, Koichi ^a   Bouaziz, Jean David ^a   Haas, Karen M ^a   Poe, Jonathan C ^a   Fujimoto, Manabu ^b   Tedder, Thomas F ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

CELLIMMUNO

Indexed keywords

CD1 ANTIGEN; CD19 ANTIBODY; CD20 ANTIBODY; CD45 ANTIGEN; CD5 ANTIGEN; INTERLEUKIN 10;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; GENE OVEREXPRESSION; INFLAMMATION; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; WILD TYPE;

ANIMALS; ANTIGENS, CD1; ANTIGENS, CD5; B-LYMPHOCYTE SUBSETS; CYTOKINES; IMMUNOPHENOTYPING; INFLAMMATION; INTERLEUKIN-10; LYMPHOCYTE DEPLETION; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; PERITONEAL CAVITY; PHENOTYPE; SPLEEN; T-LYMPHOCYTES;

EID: 43049156086     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2008.03.017     Document Type: Article

References (46)

1. Asadullah K., Sterry W., and Volk H.D. Interleukin-10 therapy-review of a new approach. Pharmacol. Rev. 55 (2003) 241-269
2. Berg D.J., Leach M.W., Kuhn R., Rajewsky K., Muller W., Davidson N.J., and Rennick D. Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J. Exp. Med. 182 (1995) 99-108
3. + T cell activation in mice. Proc. Natl. Acad. Sci. USA 104 (2007) 20882-20887
4. Brummel R., and Lenert P. Activation of marginal zone B cells from lupus mice with type A(D) CpG-oligodeoxynucleotides. J. Immunol. 174 (2005) 2429-2434
5. + dendritic cells. J. Exp. Med. 204 (2007) 3147-3156
6. + T cells to protein antigens in vivo. J. Immunol. 155 (1995) 3734-3741
7. Dass S., Vital E.M., and Emery P. Development of psoriasis after B cell depletion with rituximab. Arthritis Rheum. 56 (2007) 2715-2718
8. DiLillo D.J., Hamaguchi Y., Ueda Y., Yang K., Uchida J., Haas K.M., Kelsoe G., and Tedder T.F. Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. J. Immunol. 180 (2008) 361-371
9. Duan B., Croker B.P., and Morel L. Lupus resistance is associated with marginal zone abnormalities in an NZM murine model. Lab. Invest. 87 (2007) 14-28
10. Edwards J.C., and Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat. Rev. Immunol. 6 (2006) 394-403
11. Evans J.G., Chavez-Rueda K.A., Eddaoudi A., Meyer-Bahlburg A., Rawlings D.J., Ehrenstein M.R., and Mauri C. Novel suppressive function of transitional 2 B cells in experimental arthritis. J. Immunol. 178 (2007) 7868-7878
12. Ferguson T.A., Dube P., and Griffith T.S. Regulation of contact hypersensitivity by interleukin 10. J. Exp. Med. 179 (1994) 1597-1604
13. Fillatreau S., Sweenie C.H., McGeachy M.J., Gray D., and Anderton S.M. B cells regulate autoimmunity by provision of IL-10. Nat. Immunol. 3 (2002) 944-950
14. Goetz M., Atreya R., Ghalibafian M., Galle P.R., and Neurath M.F. Exacerbation of ulcerative colitis after rituximab salvage therapy. Inflamm. Bowel Dis. 13 (2007) 1365-1368
15. Haas K.M., Poe J.C., Steeber D.A., and Tedder T.F. B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. Immunity 23 (2005) 7-18
16. Hamaguchi Y., Uchida J., Cain D.W., Venturi G.M., Poe J.C., Haas K.M., and Tedder T.F. The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. J. Immunol. 174 (2005) 4389-4399
17. Harris D.P., Haynes L., Sayles P.C., Duso D.K., Eaton S.M., Lepak N.M., Johnson L.L., Swain S.L., and Lund F.E. Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat. Immunol. 1 (2000) 475-482
18. Hasegawa M., Hamaguchi Y., Yanaba K., Bouaziz J.-D., Uchida J., Fujimoto M., Matsushita T., Matsushita Y., Horikawa M., Komura K., et al. B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. Am. J. Pathol. 169 (2006) 954-966
19. Hauser S.L., Waubant E., Arnold D.L., Vollmer T., Antel J., Fox R.J., Bar-Or A., Panzara M., Sarkar N., Agarwal S., et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N. Engl. J. Med. 358 (2008) 676-688
20. Inaoki M., Sato S., Weintraub B.C., Goodnow C.C., and Tedder T.F. CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J. Exp. Med. 186 (1997) 1923-1931
21. Itakura A., Szczepanik M., Campos R.A., Paliwal V., Majewska M., Matsuda H., Takatsu K., and Askenase P.W. An hour after immunization peritoneal B-1 cells are activated to migrate to lymphoid organs where within 1 day they produce IgM antibodies that initiate elicitation of contact sensitivity. J. Immunol. 175 (2005) 7170-7178
22. Kripke M.L., Munn C.G., Jeevan A., Tang J.M., and Bucana C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J. Immunol. 145 (1990) 2833-2838
23. Kuhn R., Lohler J., Rennick D., Rajewsky K., and Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75 (1993) 263-274
24. Linton P.J., Bautista B., Biederman E., Bradley E.S., Harbertson J., Kondrack R.M., Padrick R.C., and Bradley L.M. Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo. J. Exp. Med. 197 (2003) 875-883
25. + T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis. J. Immunol. 178 (2007) 3447-3456
26. Martin F., Oliver A.M., and Kearney J.F. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14 (2001) 617-629
27. Matsushita T., Fujimoto M., Hasegawa M., Komura K., Takehara K., Tedder T.F., and Sato S. Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response. Am. J. Pathol. 168 (2006) 812-821
28. Mauri C., Gray D., Mushtaq N., and Londei M. Prevention of arthritis by interleukin 10-producing B cells. J. Exp. Med. 197 (2003) 489-501
29. + regulatory cells within the central nervous system. J. Immunol. 175 (2005) 3025-3032
30. Mizoguchi A., and Bhan A.K. A case for regulatory B cells. J. Immunol. 176 (2006) 705-710
31. Mizoguchi A., Mizoguchi E., Takedatsu H., Blumberg R.S., and Bhan A.K. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16 (2002) 219-230
32. Sato S., Ono N., Steeber D.A., Pisetsky D.S., and Tedder T.F. CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity. J. Immunol. 157 (1996) 4371-4378
33. Sato S., Steeber D.A., Jansen P.J., and Tedder T.F. CD19 expression levels regulate B lymphocyte development: Human CD19 restores normal function in mice lacking endogenous CD19. J. Immunol. 158 (1997) 4662-4669
34. Sato S., Steeber D.A., and Tedder T.F. The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation. Proc. Natl. Acad. Sci. USA 92 (1995) 11558-11562
35. Schwarz A., Grabbe S., Riemann H., Aragane Y., Simon M., Manon S., Andrade S., Luger T.A., Zlotnik A., and Schwarz T. In vivo effects of interleukin-10 on contact hypersensitivity and delayed-type hypersensitivity reactions. J. Invest. Dermatol. 103 (1994) 211-216
36. - B cells: Possible involvement in age-associated cytokine dysregulation. Int. Immunol. 9 (1997) 745-754
37. Tedder T.F. Response-regulators of B lymphocyte signaling thresholds provide a context for antigen receptor signal transduction. Semin. Immunol. 10 (1998) 259-265
38. Tedder T.F., Steeber D.A., and Pizcueta P. L-selectin deficient mice have impaired leukocyte recruitment into inflammatory sites. J. Exp. Med. 181 (1995) 2259-2264
39. Uchida J., Hamaguchi Y., Oliver J.A., Ravetch J.V., Poe J.C., Haas K.M., and Tedder T.F. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J. Exp. Med. 199 (2004) 1659-1669
40. Uchida J., Lee Y., Hasegawa M., Liang Y., Bradney A., Oliver J.A., Bowen K., Steeber D.A., Haas K.M., Poe J.C., and Tedder T.F. Mouse CD20 expression and function. Int. Immunol. 16 (2004) 119-129
41. Venturi G.M., Tu L., Kadono T., Khan A.I., Fujimoto Y., Oshel P., Bock C.B., Miller A.S., Albrecht R.M., Kubes P., et al. Leukocyte migration is regulated by L-selectin endoproteolytic release. Immunity 19 (2003) 713-724
42. + type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity. J. Immunol. 165 (2000) 6783-6790
43. Watanabe R., Fujimoto M., Ishiura N., Kuwano Y., Nakashima H., Yazawa N., Okochi H., Sato S., Tedder T.F., and Tamaki K. CD19 expression in B cells is important for suppression of contact hypersensitivity. Am. J. Pathol. 171 (2007) 560-570
44. Xiu Y., Wong C.P., Hamaguchi Y., Wang Y., Pop S., Tisch R.M., and Tedder T.F. B lymphocytes depletion by CD20 monoclonal antibody prevents diabetes in NOD mice despite isotype-specific differences in FcγR effector functions. J. Immunol. 180 (2008) 2863-2875
45. Yanaba K., Hamaguchi Y., Venturi G.M., Steeber D.A., St.Clair E.W., and Tedder T.F. B cell depletion delays collagen-induced arthritis in mice: Arthritis induction requires synergy between humoral and cell-mediated immunity. J. Immunol. 179 (2007) 1369-1380
46. Yazawa N., Hamaguchi Y., Poe J.C., and Tedder T.F. Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease. Proc. Natl. Acad. Sci. USA 102 (2005) 15178-15183