Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes

Antiviral Research

Volumn 107, Issue 1, 2014, Pages 16-22

  Schubert, Axel ^a   Gentner, Eva ^a   Bohn, Kathrin ^b   Schwarz, Maximilian ^b   Mertens, Thomas ^a   Sauerbrei, Andreas ^b  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

HSCT; HSV 1; Resistance genotype; Resistance phenotype

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACICLOVIR; DNA POLYMERASE; FOSCARNET; NUCLEOSIDE ANALOG; PENCICLOVIR; THYMIDINE KINASE; VIRUS DNA; ANTIVIRUS AGENT; BROXURIDINE; DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE, SIMPLEXVIRUS; EXODEOXYRIBONUCLEASE; VIRUS PROTEIN;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; FRAMESHIFT MUTATION; GENE INSERTION; GENE MUTATION; GENOTYPE; HERPES SIMPLEX VIRUS 1; HUMAN; MALE; NONHUMAN; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURAL GENE; VIRUS GENE; VIRUS ISOLATION; VIRUS STRAIN; ADOLESCENT; AGED; ANALOGS AND DERIVATIVES; ANTIVIRAL RESISTANCE; CHEMISTRY; CHILD; DNA SEQUENCE; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HERPES SIMPLEX; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MIDDLE AGED; MISSENSE MUTATION; POINT MUTATION; VIROLOGY; YOUNG ADULT;

ACYCLOVIR; ADOLESCENT; ADULT; AGED; ANTIVIRAL AGENTS; BROMODEOXYURIDINE; CHILD; DNA, VIRAL; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, VIRAL; EXODEOXYRIBONUCLEASES; FEMALE; FRAMESHIFT MUTATION; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; MUTATION, MISSENSE; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; THYMIDINE KINASE; VIRAL PROTEINS; YOUNG ADULT;

EID: 84899540353     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.03.015     Document Type: Article

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