-
1
-
-
0038421037
-
Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids
-
Bestman-Smith, J., and G. Boivin. 2003. Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids. J. Virol. 77:7820-7829.
-
(2003)
J. Virol.
, vol.77
, pp. 7820-7829
-
-
Bestman-Smith, J.1
Boivin, G.2
-
2
-
-
0035103886
-
Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues
-
Bestman-Smith, J., I. Schmit, B. Papadopoulou, and G. Boivin. 2001. Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues. J. Virol. 75:3105-3110.
-
(2001)
J. Virol.
, vol.75
, pp. 3105-3110
-
-
Bestman-Smith, J.1
Schmit, I.2
Papadopoulou, B.3
Boivin, G.4
-
3
-
-
0027514853
-
A cosmid-based system for constructing mutants of herpes simplex virus type 1
-
Cunningham, C., and A. J. Davison. 1993. A cosmid-based system for constructing mutants of herpes simplex virus type 1. Virology 197:116-124.
-
(1993)
Virology
, vol.197
, pp. 116-124
-
-
Cunningham, C.1
Davison, A.J.2
-
4
-
-
0022550413
-
Evidence that the "active centre" of the herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide
-
Darby, G., B. A. Larder, and M. M. Inglis. 1986. Evidence that the "active centre" of the herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide. J. Gen. Virol. 67:753-758.
-
(1986)
J. Gen. Virol.
, vol.67
, pp. 753-758
-
-
Darby, G.1
Larder, B.A.2
Inglis, M.M.3
-
5
-
-
0024492496
-
Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome
-
Erlich, K. E., J. Mills, P. Chatis, G. J. Mertz, B. F. Busch, S. E. Follansbee, R. M. Grant, and C. S. Crumpacker. 1989. Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 320:293-296.
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 293-296
-
-
Erlich, K.E.1
Mills, J.2
Chatis, P.3
Mertz, G.J.4
Busch, B.F.5
Follansbee, S.E.6
Grant, R.M.7
Crumpacker, C.S.8
-
6
-
-
0031821936
-
Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients
-
Gaudreau, A., E. Hill, H. H. Balfour, Jr., A. Erice, and G. Boivin. 1998. Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients. J. Infect. Dis. 178:297-303.
-
(1998)
J. Infect. Dis.
, vol.178
, pp. 297-303
-
-
Gaudreau, A.1
Hill, E.2
Balfour Jr., H.H.3
Erice, A.4
Boivin, G.5
-
7
-
-
0036527281
-
Resistance of herpesviruses to antiviral drugs: Clinical impacts and molecular mechanisms
-
Gilbert, C., J. Bestman-Smith, and G. Boivin. 2002. Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms. Drug Resist. Updates 5:88-114.
-
(2002)
Drug Resist. Updates
, vol.5
, pp. 88-114
-
-
Gilbert, C.1
Bestman-Smith, J.2
Boivin, G.3
-
8
-
-
0028898550
-
An altered spectrum of herpes simplex virus mutations mediated by an antimutator DNA polymerase
-
Hwang, C. B., and H. J. Chen. 1995. An altered spectrum of herpes simplex virus mutations mediated by an antimutator DNA polymerase. Gene 152:191-193.
-
(1995)
Gene
, vol.152
, pp. 191-193
-
-
Hwang, C.B.1
Chen, H.J.2
-
9
-
-
0024205276
-
The herpes simplex virus DNA polymerase: Analysis of the functional domains
-
Knopf, C. W., and K. Weisshart. 1988. The herpes simplex virus DNA polymerase: analysis of the functional domains. Biochim. Biophys. Acta 951:298-314.
-
(1988)
Biochim. Biophys. Acta
, vol.951
, pp. 298-314
-
-
Knopf, C.W.1
Weisshart, K.2
-
10
-
-
0031656502
-
Polymorphisms of thymidine kinase gene in herpes simplex virus type 1: Analysis of clinical isolates from herpetic keratitis patients and laboratory strains
-
Kudo, E., H. Shiota, T. Naito, K. Satake, and M. Itakura. 1998. Polymorphisms of thymidine kinase gene in herpes simplex virus type 1: analysis of clinical isolates from herpetic keratitis patients and laboratory strains. J. Med. Virol. 56:151-158.
-
(1998)
J. Med. Virol.
, vol.56
, pp. 151-158
-
-
Kudo, E.1
Shiota, H.2
Naito, T.3
Satake, K.4
Itakura, M.5
-
11
-
-
0032831823
-
Role of genotypic analysis of the thymidine kinase gene of herpes simplex virus for determination of neurovirulence and resistance to acyclovir
-
Lee, N. Y., Y. Tang, M. J. Espy, C. P. Kolbert, P. N. Rys, P. S. Mitchell, S. P. Day, S. L. Henry, D. H. Persing, and T. F. Smith. 1999. Role of genotypic analysis of the thymidine kinase gene of herpes simplex virus for determination of neurovirulence and resistance to acyclovir. J. Clin. Microbiol. 37:3171-3174.
-
(1999)
J. Clin. Microbiol.
, vol.37
, pp. 3171-3174
-
-
Lee, N.Y.1
Tang, Y.2
Espy, M.J.3
Kolbert, C.P.4
Rys, P.N.5
Mitchell, P.S.6
Day, S.P.7
Henry, S.L.8
Persing, D.H.9
Smith, T.F.10
-
12
-
-
0023988582
-
Site-directed mutagenesis of a nucleotide-binding domain in HSV-1 thymidine kinase: Effects on catalytic activity
-
Liu, Q., and W. C. Summers. 1988. Site-directed mutagenesis of a nucleotide-binding domain in HSV-1 thymidine kinase: effects on catalytic activity. Virology 163:638-642.
-
(1988)
Virology
, vol.163
, pp. 638-642
-
-
Liu, Q.1
Summers, W.C.2
-
13
-
-
0033913918
-
Genetic characterization of thymidine kinase from acyclovir-resistant and susceptible herpes simplex virus type 1 isolated from bone marrow transplant recipients
-
Morfin, F., G. Souillet, K. Bilger, T. Ooka, M. Aymard, and D. Thouvenot. 2000. Genetic characterization of thymidine kinase from acyclovir-resistant and susceptible herpes simplex virus type 1 isolated from bone marrow transplant recipients. J. Infect. Dis. 182:290-293.
-
(2000)
J. Infect. Dis.
, vol.182
, pp. 290-293
-
-
Morfin, F.1
Souillet, G.2
Bilger, K.3
Ooka, T.4
Aymard, M.5
Thouvenot, D.6
-
14
-
-
0024354415
-
Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity?
-
Sacks, S. L., R. J. Wanklin, D. E. Reece, K. A. Hicks, K. L. Tyler, and D. M. Coen. 1989. Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity? Ann. Intern. Med. 111:893-899.
-
(1989)
Ann. Intern. Med.
, vol.111
, pp. 893-899
-
-
Sacks, S.L.1
Wanklin, R.J.2
Reece, D.E.3
Hicks, K.A.4
Tyler, K.L.5
Coen, D.M.6
-
15
-
-
0028118607
-
Foscarnet-resistant herpes simplex virus infection in patients with AIDS
-
Safrin, S., S. Kemmerly, B. Plotkin, T. Smith, N. Weissbach, D. De Veranez, L. D. Phan, and D. Cohn. 1994. Foscarnet-resistant herpes simplex virus infection in patients with AIDS. J. Infect. Dis. 169:193-196.
-
(1994)
J. Infect. Dis.
, vol.169
, pp. 193-196
-
-
Safrin, S.1
Kemmerly, S.2
Plotkin, B.3
Smith, T.4
Weissbach, N.5
De Veranez, D.6
Phan, L.D.7
Cohn, D.8
-
16
-
-
0030901540
-
Homopolymer mutational hot spots mediate herpes simplex virus resistance to acyclovir
-
Sasadeusz, J. J., F. Tufaro, S. Safrin, K. Schubert, M. M. Hubinette, P. K. Cheung, and S. L. Sacks. 1997. Homopolymer mutational hot spots mediate herpes simplex virus resistance to acyclovir. J. Virol. 71:3872-3878.
-
(1997)
J. Virol.
, vol.71
, pp. 3872-3878
-
-
Sasadeusz, J.J.1
Tufaro, F.2
Safrin, S.3
Schubert, K.4
Hubinette, M.M.5
Cheung, P.K.6
Sacks, S.L.7
-
17
-
-
0033495719
-
Characterization of the DNA polymerase and thymidine kinase genes of herpes simplex virus isolates from AIDS patients in whom acyclovir and foscarnet therapy sequentially failed
-
Schmit, I., and G. Boivin. 1999. Characterization of the DNA polymerase and thymidine kinase genes of herpes simplex virus isolates from AIDS patients in whom acyclovir and foscarnet therapy sequentially failed. J. Infect. Dis. 180:487-490.
-
(1999)
J. Infect. Dis.
, vol.180
, pp. 487-490
-
-
Schmit, I.1
Boivin, G.2
-
18
-
-
10744231664
-
Differential mutation patterns in thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 clones passaged in the presence of acyclovir or penciclovir
-
Suzutani, T., K. Ishioka, E. De Clercq, K. Ishibashi, H. Kaneko, T. Kira, K. Hashimoto, M. Ogasawara, K. Ohtani, N. Wakamiya, and M. Sago. 2003. Differential mutation patterns in thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 clones passaged in the presence of acyclovir or penciclovir. Antimicrob. Agents Chemother. 47:1707-1713.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 1707-1713
-
-
Suzutani, T.1
Ishioka, K.2
De Clercq, E.3
Ishibashi, K.4
Kaneko, H.5
Kira, T.6
Hashimoto, K.7
Ogasawara, M.8
Ohtani, K.9
Wakamiya, N.10
Sago, M.11
-
19
-
-
0027472269
-
Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS
-
Talarico, C. L., W. C. Phelps, and K. K. Biron. 1993. Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS. J. Virol. 67:1024-1033.
-
(1993)
J. Virol.
, vol.67
, pp. 1024-1033
-
-
Talarico, C.L.1
Phelps, W.C.2
Biron, K.K.3
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