Significance of amino acid substitutions in the thymidine kinase gene of herpes simplex virus type 1 for resistance

Antiviral Research

Volumn 96, Issue 2, 2012, Pages 105-107

  Sauerbrei, Andreas ^a   Liermann, Kristin ^a   Bohn, Kathrin ^a   Henke, Andreas ^a   Zell, Roland ^a   Gronowitz, Simon ^b   Wutzler, Peter ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b Biovica International AB   (Sweden)

Author keywords

HSV 1; Resistance; Site directed mutagenesis; Thymidine kinase

Indexed keywords

AMINO ACID; BROXURIDINE; THYMIDINE KINASE;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SEQUENCE; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; VIRUS RESISTANCE;

AMINO ACID SUBSTITUTION; ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; HERPESVIRUS 1, HUMAN; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; THYMIDINE KINASE;

HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 84867236135     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2012.08.001     Document Type: Article

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