Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus

Antiviral Research

Volumn 86, Issue 3, 2010, Pages 246-252

  Sauerbrei, A ^a   Deinhardt, S ^a   Zell, R ^a   Wutzler, P ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

DNA polymerase; Genotypic resistance; Herpes simplex virus; Phenotypic resistance; Thymidine kinase

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACICLOVIR; CIDOFOVIR; DNA POLYMERASE; FOSCARNET; PENCICLOVIR; THYMIDINE KINASE;

ANIMAL CELL; ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; DNA POLYMORPHISM; FRAMESHIFT MUTATION; GENE MUTATION; GENOTYPE; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VIRUS RESISTANCE; VIRUS STRAIN;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; BROMODEOXYURIDINE; CELL SURVIVAL; CELLS, CULTURED; CYTOSINE; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, VIRAL; EXODEOXYRIBONUCLEASES; FOSCARNET; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; OXIDATION-REDUCTION; PHOSPHONIC ACIDS; SEQUENCE ANALYSIS, DNA; STAINING AND LABELING; TETRAZOLIUM SALTS; THYMIDINE KINASE; VIRAL PROTEINS;

HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 77952668445     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2010.03.002     Document Type: Article

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