Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Nature

Volumn 508, Issue 7497, 2014, Pages 541-545

  Liu, Pengda ^a   Begley, Michael ^a,b   Michowski, Wojciech ^a   Inuzuka, Hiroyuki ^a   Ginzberg, Miriam ^a   Gao, Daming ^a   Tsou, Peiling ^a,b   Gan, Wenjian ^a   Papa, Antonella ^a,b   Kim, Byeong Mo ^b   Wan, Lixin ^a   Singh, Amrik ^c   Zhai, Bo ^a   Yuan, Min ^b   Wang, Zhiwei ^a,d   Gygi, Steven P ^a   Lee, Tae Ho ^b   Lu, Kun Ping ^b   Toker, Alex ^a   Pandolfi, Pier Paolo ^a,b   Asara, John M ^b   Kirschner, Marc W ^a   Sicinski, Piotr ^a   Cantley, Lewis ^a,b,e   Wei, Wenyi ^a   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c CELL SIGNALING TECHNOLOGY   (United States)

^d SOOCHOW UNIVERSITY   (China)

^e NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN A2; CYCLIN DEPENDENT KINASE 2; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B;

ALLELE; APOPTOSIS; CANCER; CARBOXYLIC ACID; CELL ORGANELLE; ENZYME ACTIVITY; FACILITATION; METABOLISM; PHOSPHORUS;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CYCLIN A2; CYCLIN-DEPENDENT KINASE 2; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; MALE; MICE; MULTIPROTEIN COMPLEXES; NEOPLASMS; OLFACTORY BULB; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTHREONINE; PROTO-ONCOGENE PROTEINS C-AKT; TOR SERINE-THREONINE KINASES;

EID: 84899484738     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13079     Document Type: Article

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