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Volumn 355, Issue 3, 2014, Pages 485-514

Experimental tools to monitor the dynamics of endothelial barrier function: A survey of in vitro approaches

Author keywords

Electric cell substrate impedance sensing; Endothelium; Impedance analysis; Permeability; Transendothelial electrical resistance

Indexed keywords

BLOOD BRAIN BARRIER; CELL CULTURE; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM CELL; HUMAN; IMPEDANCE; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

EID: 84899459123     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-014-1810-3     Document Type: Review
Times cited : (51)

References (184)
  • 1
    • 33846798106 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium. I. Structure, function, and mechanisms
    • 17272818
    • Aird WC (2007a) Phenotypic heterogeneity of the endothelium. I. Structure, function, and mechanisms. Circ Res 100:158-173
    • (2007) Circ Res , vol.100 , pp. 158-173
    • Aird, W.C.1
  • 2
    • 33846849237 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium. II. Representative vascular beds
    • 17272819
    • Aird WC (2007b) Phenotypic heterogeneity of the endothelium. II. Representative vascular beds. Circ Res 100:174-190
    • (2007) Circ Res , vol.100 , pp. 174-190
    • Aird, W.C.1
  • 5
    • 84880034935 scopus 로고    scopus 로고
    • Atherosclerotic plaques: Is endothelial shear stress the only factor?
    • 23688740
    • Anssari-Benam A, Korakianitis T (2013) Atherosclerotic plaques: is endothelial shear stress the only factor? Med Hypotheses 81:235-239
    • (2013) Med Hypotheses , vol.81 , pp. 235-239
    • Anssari-Benam, A.1    Korakianitis, T.2
  • 6
    • 0346996456 scopus 로고    scopus 로고
    • Bioelectrical impedance assay to monitor changes in cell shape during apoptosis
    • 14683642
    • Arndt S, Seebach J, Psathaki K, Galla HJ, Wegener J (2004) Bioelectrical impedance assay to monitor changes in cell shape during apoptosis. Biosens Bioelectron 19:583-594
    • (2004) Biosens Bioelectron , vol.19 , pp. 583-594
    • Arndt, S.1    Seebach, J.2    Psathaki, K.3    Galla, H.J.4    Wegener, J.5
  • 8
    • 0028910024 scopus 로고
    • Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers
    • 7733381
    • Barbee KA, Mundel T, Lal R, Davies PF (1995) Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers. Am J Physiol 268:H1765-H1772
    • (1995) Am J Physiol , vol.268
    • Barbee, K.A.1    Mundel, T.2    Lal, R.3    Davies, P.F.4
  • 10
    • 77954333963 scopus 로고    scopus 로고
    • Vascular endothelial growth factors and vascular permeability
    • 2895541 20400620
    • Bates DO (2010) Vascular endothelial growth factors and vascular permeability. Cardiovasc Res 87:262-271
    • (2010) Cardiovasc Res , vol.87 , pp. 262-271
    • Bates, D.O.1
  • 11
    • 78649327676 scopus 로고    scopus 로고
    • Endothelial glycocalyx and coronary vascular permeability: The fringe benefit
    • 20859744
    • Becker BF, Chappell D, Jacob M (2010) Endothelial glycocalyx and coronary vascular permeability: the fringe benefit. Basic Res Cardiol 105:687-701
    • (2010) Basic Res Cardiol , vol.105 , pp. 687-701
    • Becker, B.F.1    Chappell, D.2    Jacob, M.3
  • 12
    • 70349514839 scopus 로고    scopus 로고
    • Stretch and shear interactions affect intercellular junction protein expression and turnover in endothelial cells
    • Berardi DE, Tarbell JM (2009) Stretch and shear interactions affect intercellular junction protein expression and turnover in endothelial cells. Cel Mol Bioeng 2:320-331
    • (2009) Cel Mol Bioeng , vol.2 , pp. 320-331
    • Berardi, D.E.1    Tarbell, J.M.2
  • 13
    • 84876468081 scopus 로고    scopus 로고
    • Recent advances in high resolution scanning electrochemical microscopy of living cells - A review
    • 23601970
    • Bergner S, Vatsyayan P, Matysik FM (2013) Recent advances in high resolution scanning electrochemical microscopy of living cells - a review. Anal Chim Acta 775:1-13
    • (2013) Anal Chim Acta , vol.775 , pp. 1-13
    • Bergner, S.1    Vatsyayan, P.2    Matysik, F.M.3
  • 15
    • 80053344681 scopus 로고    scopus 로고
    • Acute laminar shear stress reversibly increases human glomerular endothelial cell permeability via activation of endothelial nitric oxide synthase
    • 3191806 21775480
    • Bevan HS, Slater SC, Clarke H, Cahill PA, Mathieson PW, Welsh GI, Satchell SC (2011) Acute laminar shear stress reversibly increases human glomerular endothelial cell permeability via activation of endothelial nitric oxide synthase. Am J Physiol Renal Physiol 301:F733-F742
    • (2011) Am J Physiol Renal Physiol , vol.301
    • Bevan, H.S.1    Slater, S.C.2    Clarke, H.3    Cahill, P.A.4    Mathieson, P.W.5    Welsh, G.I.6    Satchell, S.C.7
  • 18
    • 33646525704 scopus 로고    scopus 로고
    • Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch
    • 1606576 16651639
    • Birukova AA, Chatchavalvanich S, Rios A, Kawkitinarong K, Garcia JG, Birukov KG (2006) Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch. Am J Pathol 168:1749-1761
    • (2006) Am J Pathol , vol.168 , pp. 1749-1761
    • Birukova, A.A.1    Chatchavalvanich, S.2    Rios, A.3    Kawkitinarong, K.4    Garcia, J.G.5    Birukov, K.G.6
  • 19
    • 33947151568 scopus 로고    scopus 로고
    • Scanning ion conductance microscopy with distance-modulated shear force control
    • Böcker M, Anczykowski B, Wegener JTS (2007) Scanning ion conductance microscopy with distance-modulated shear force control. Nanotechnology 18:145505
    • (2007) Nanotechnology , vol.18 , pp. 145505
    • Böcker, M.1    Anczykowski, B.2    Wegener, J.T.S.3
  • 21
    • 77952316102 scopus 로고    scopus 로고
    • Lymphatic endothelial cells adapt their barrier function in response to changes in shear stress
    • 2883493 20143922
    • Breslin JW, Kurtz KM (2009) Lymphatic endothelial cells adapt their barrier function in response to changes in shear stress. Lymphat Res Biol 7:229-237
    • (2009) Lymphat Res Biol , vol.7 , pp. 229-237
    • Breslin, J.W.1    Kurtz, K.M.2
  • 22
    • 77951074809 scopus 로고    scopus 로고
    • High glucose-mediated loss of cell surface heparan sulfate proteoglycan impairs the endothelial shear stress response
    • 20217676
    • Brower JB, Targovnik JH, Caplan MR, Massia SP (2010) High glucose-mediated loss of cell surface heparan sulfate proteoglycan impairs the endothelial shear stress response. Cytoskeleton 67:135-141
    • (2010) Cytoskeleton , vol.67 , pp. 135-141
    • Brower, J.B.1    Targovnik, J.H.2    Caplan, M.R.3    Massia, S.P.4
  • 23
    • 15944403522 scopus 로고    scopus 로고
    • Analysis of flow in a cone-and-plate apparatus with respect to spatial and temporal effects on endothelial cells
    • 15648084
    • Buschmann MH, Dieterich P, Adams NA, Schnittler HJ (2005) Analysis of flow in a cone-and-plate apparatus with respect to spatial and temporal effects on endothelial cells. Biotechnol Bioeng 89:493-502
    • (2005) Biotechnol Bioeng , vol.89 , pp. 493-502
    • Buschmann, M.H.1    Dieterich, P.2    Adams, N.A.3    Schnittler, H.J.4
  • 24
    • 34547094104 scopus 로고    scopus 로고
    • In vitro study of LDL transport under pressurized (convective) conditions
    • 17322415
    • Cancel LM, Fitting A, Tarbell JM (2007) In vitro study of LDL transport under pressurized (convective) conditions. Am J Physiol Heart Circ Physiol 293:H126-H132
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Cancel, L.M.1    Fitting, A.2    Tarbell, J.M.3
  • 25
    • 0023875392 scopus 로고
    • Comparison of transcellular and transepithelial water osmotic permeabilities (Pos) in the isolated proximal straight tubule (PST) of the rabbit kidney
    • 2845357
    • Carpi-Medina P, Whittembury G (1988) Comparison of transcellular and transepithelial water osmotic permeabilities (Pos) in the isolated proximal straight tubule (PST) of the rabbit kidney. Pflugers Arch 412:66-74
    • (1988) Pflugers Arch , vol.412 , pp. 66-74
    • Carpi-Medina, P.1    Whittembury, G.2
  • 26
    • 0033956824 scopus 로고    scopus 로고
    • Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism
    • 10634798
    • Chang YS, Yaccino JA, Lakshminarayanan S, Frangos JA, Tarbell JM (2000) Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism. Arterioscler Thromb Vasc Biol 20:35-42
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 35-42
    • Chang, Y.S.1    Yaccino, J.A.2    Lakshminarayanan, S.3    Frangos, J.A.4    Tarbell, J.M.5
  • 28
    • 40949093622 scopus 로고    scopus 로고
    • Effects of disturbed flow on endothelial cells
    • 3718045 18172767
    • Chien S (2008) Effects of disturbed flow on endothelial cells. Ann Biomed Eng 36:554-562
    • (2008) Ann Biomed Eng , vol.36 , pp. 554-562
    • Chien, S.1
  • 29
    • 33947588287 scopus 로고    scopus 로고
    • An endothelial cell compatible biosensor fabricated using optically thin indium tin oxide silicon nitride electrodes
    • 17113768
    • Choi CK, English AE, Jun SI, Kihm KD, Rack PD (2007) An endothelial cell compatible biosensor fabricated using optically thin indium tin oxide silicon nitride electrodes. Biosens Bioelectron 22:2585-2590
    • (2007) Biosens Bioelectron , vol.22 , pp. 2585-2590
    • Choi, C.K.1    English, A.E.2    Jun, S.I.3    Kihm, K.D.4    Rack, P.D.5
  • 30
    • 0017855840 scopus 로고
    • Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens
    • 641977
    • Claude P (1978) Morphological factors influencing transepithelial permeability: a model for the resistance of the zonula occludens. J Membr Biol 39:219-232
    • (1978) J Membr Biol , vol.39 , pp. 219-232
    • Claude, P.1
  • 31
    • 0032713547 scopus 로고    scopus 로고
    • VEGF stimulates tyrosine phosphorylation of beta-catenin and small-pore endothelial barrier dysfunction
    • Cohen AW, Carbajal JM, Schaeffer RC (1999) VEGF stimulates tyrosine phosphorylation of beta-catenin and small-pore endothelial barrier dysfunction. Am J Physiol Heart Circ Physiol 277:H2038-H2049
    • (1999) Am J Physiol Heart Circ Physiol , vol.277
    • Cohen, A.W.1    Carbajal, J.M.2    Schaeffer, R.C.3
  • 33
    • 84878611663 scopus 로고    scopus 로고
    • Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1
    • 23684974
    • Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA (2013) Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol 23:1024-1030
    • (2013) Curr Biol , vol.23 , pp. 1024-1030
    • Conway, D.E.1    Breckenridge, M.T.2    Hinde, E.3    Gratton, E.4    Chen, C.S.5    Schwartz, M.A.6
  • 34
    • 79955752356 scopus 로고    scopus 로고
    • The role of shear stress in blood-brain barrier endothelial physiology
    • 3103473 21569296
    • Cucullo L, Hossain M, Puvenna V, Marchi N, Janigro D (2011) The role of shear stress in blood-brain barrier endothelial physiology. BMC Neurosci 12:40
    • (2011) BMC Neurosci , vol.12 , pp. 40
    • Cucullo, L.1    Hossain, M.2    Puvenna, V.3    Marchi, N.4    Janigro, D.5
  • 37
    • 0024371272 scopus 로고
    • Response of cultured endothelial cells to mechanical stimulation
    • 2764859
    • Dartsch PC, Betz E (1989) Response of cultured endothelial cells to mechanical stimulation. Basic Res Cardiol 84:268-281
    • (1989) Basic Res Cardiol , vol.84 , pp. 268-281
    • Dartsch, P.C.1    Betz, E.2
  • 38
    • 0026164818 scopus 로고
    • Mechanical sensing mechanisms: Shear stress and endothelial cells
    • 2027217
    • Davies PF (1991) Mechanical sensing mechanisms: shear stress and endothelial cells. J Vasc Surg 13:729-731
    • (1991) J Vasc Surg , vol.13 , pp. 729-731
    • Davies, P.F.1
  • 39
    • 0030966201 scopus 로고    scopus 로고
    • Overview: Temporal and spatial relationships in shear stress-mediated endothelial signalling
    • 9226302
    • Davies PF (1997) Overview: temporal and spatial relationships in shear stress-mediated endothelial signalling. J Vasc Res 34:208-211
    • (1997) J Vasc Res , vol.34 , pp. 208-211
    • Davies, P.F.1
  • 40
    • 0021253310 scopus 로고
    • Influence of hemodynamic forces on vascular endothelial function. in vitro studies of shear stress and pinocytosis in bovine aortic cells
    • 425126 6707208
    • Davies PF, Dewey CF Jr, Bussolari SR, Gordon EJ, Gimbrone MA Jr (1984) Influence of hemodynamic forces on vascular endothelial function. In vitro studies of shear stress and pinocytosis in bovine aortic cells. J Clin Invest 73:1121-1129
    • (1984) J Clin Invest , vol.73 , pp. 1121-1129
    • Davies, P.F.1    Dewey, Jr.C.F.2    Bussolari, S.R.3    Gordon, E.J.4    Gimbrone, Jr.M.A.5
  • 42
    • 0037423813 scopus 로고    scopus 로고
    • Spatial microstimuli in endothelial mechanosignaling
    • 12623874
    • Davies PF, Zilberberg J, Helmke BP (2003) Spatial microstimuli in endothelial mechanosignaling. Circ Res 92:359-370
    • (2003) Circ Res , vol.92 , pp. 359-370
    • Davies, P.F.1    Zilberberg, J.2    Helmke, B.P.3
  • 44
    • 84879860325 scopus 로고    scopus 로고
    • Endothelial adherens junctions at a glance
    • 23781019
    • Dejana E, Orsenigo F (2013) Endothelial adherens junctions at a glance. J Cell Sci 126:2545-2549
    • (2013) J Cell Sci , vol.126 , pp. 2545-2549
    • Dejana, E.1    Orsenigo, F.2
  • 47
  • 50
    • 84873835618 scopus 로고    scopus 로고
    • Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury
    • 3668557 23212101
    • Dubrovskyi O, Birukova AA, Birukov KG (2013) Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury. Lab Invest 93:254-263
    • (2013) Lab Invest , vol.93 , pp. 254-263
    • Dubrovskyi, O.1    Birukova, A.A.2    Birukov, K.G.3
  • 51
    • 0035074497 scopus 로고    scopus 로고
    • The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle
    • 11259444
    • Dvorak AM, Feng D (2001) The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle. J Histochem Cytochem 49:419-432
    • (2001) J Histochem Cytochem , vol.49 , pp. 419-432
    • Dvorak, A.M.1    Feng, D.2
  • 52
    • 84869887642 scopus 로고    scopus 로고
    • TNF-alpha and TGF-beta synergistically stimulate elongation of human endothelial cells without transdifferentiation to smooth muscle cell phenotype
    • 23116662
    • Emmanuel C, Huynh M, Matthews J, Kelly E, Zoellner H (2013) TNF-alpha and TGF-beta synergistically stimulate elongation of human endothelial cells without transdifferentiation to smooth muscle cell phenotype. Cytokine 61:38-40
    • (2013) Cytokine , vol.61 , pp. 38-40
    • Emmanuel, C.1    Huynh, M.2    Matthews, J.3    Kelly, E.4    Zoellner, H.5
  • 53
    • 0028848523 scopus 로고
    • Electrical resistance measurements on cerebral capillary endothelial cells - A new technique to study small surface areas
    • 8621882
    • Erben M, Decker S, Franke H, Galla HJ (1995) Electrical resistance measurements on cerebral capillary endothelial cells - a new technique to study small surface areas. J Biochem Biophys Methods 30:227-238
    • (1995) J Biochem Biophys Methods , vol.30 , pp. 227-238
    • Erben, M.1    Decker, S.2    Franke, H.3    Galla, H.J.4
  • 54
    • 0032559597 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces endothelial fenestrations in vitro
    • 2141756 9472045
    • Esser S, Wolburg K, Wolburg H, Breier G, Kurzchalia T, Risau W (1998) Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol 140:947-959
    • (1998) J Cell Biol , vol.140 , pp. 947-959
    • Esser, S.1    Wolburg, K.2    Wolburg, H.3    Breier, G.4    Kurzchalia, T.5    Risau, W.6
  • 55
    • 0015881585 scopus 로고
    • Determination of the impedance locus of rabbit corneal endothelium
    • 1484284 4714448
    • Fischbarg J, Lim JJ (1973) Determination of the impedance locus of rabbit corneal endothelium. Biophys J 13:595-599
    • (1973) Biophys J , vol.13 , pp. 595-599
    • Fischbarg, J.1    Lim, J.J.2
  • 56
    • 0023183304 scopus 로고
    • Quantitative studies of human monokine-induced endothelial cell elongation
    • 3471830
    • FitzGerald OM, Hess EV, Chance A, Highsmith RF (1987) Quantitative studies of human monokine-induced endothelial cell elongation. J Leukoc Biol 41:421-428
    • (1987) J Leukoc Biol , vol.41 , pp. 421-428
    • Fitzgerald, O.M.1    Hess, E.V.2    Chance, A.3    Highsmith, R.F.4
  • 57
    • 70049093482 scopus 로고    scopus 로고
    • PKCdelta influences p190 phosphorylation and activity: Events independent of PKCdelta-mediated regulation of endothelial cell stress fiber and focal adhesion formation and barrier function
    • 2759355 19632305
    • Fordjour AK, Harrington EO (2009) PKCdelta influences p190 phosphorylation and activity: events independent of PKCdelta-mediated regulation of endothelial cell stress fiber and focal adhesion formation and barrier function. Biochim Biophys Acta 1790:1179-1190
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 1179-1190
    • Fordjour, A.K.1    Harrington, E.O.2
  • 60
    • 84876075461 scopus 로고    scopus 로고
    • Mechano-sensing and transduction by endothelial surface glycocalyx: Composition, structure, and function
    • Fu BM, Tarbell JM (2013) Mechano-sensing and transduction by endothelial surface glycocalyx: composition, structure, and function. Wiley Interdisc Rev Syst Biol Med 5:381-390
    • (2013) Wiley Interdisc Rev Syst Biol Med , vol.5 , pp. 381-390
    • Fu, B.M.1    Tarbell, J.M.2
  • 61
    • 0141679456 scopus 로고    scopus 로고
    • Mechanical stresses keep endothelial cells healthy: Beneficial effects of a physiological level of cyclic stretch on endothelial barrier function
    • 12959924
    • Fujiwara K (2003) Mechanical stresses keep endothelial cells healthy: beneficial effects of a physiological level of cyclic stretch on endothelial barrier function. Am J Physiol Lung Cell Mol Physiol 285:L782-L784
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Fujiwara, K.1
  • 62
    • 2142846185 scopus 로고
    • Monitoring fibroblast behavior in tissue culture with an applied electric field
    • 345299 6587391
    • Giaever I, Keese CR (1984) Monitoring fibroblast behavior in tissue culture with an applied electric field. Proc Natl Acad Sci U S A 81:3761-3764
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 3761-3764
    • Giaever, I.1    Keese, C.R.2
  • 63
    • 0025916059 scopus 로고
    • Micromotion of mammalian cells measured electrically
    • 52411 1881923
    • Giaever I, Keese CR (1991) Micromotion of mammalian cells measured electrically. Proc Natl Acad Sci U S A 88:7896-7900
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 7896-7900
    • Giaever, I.1    Keese, C.R.2
  • 64
    • 0031425656 scopus 로고    scopus 로고
    • Measurement of paracellular epithelial conductivity by conductance scanning
    • 9306019
    • Gitter AH, Bertog M, Schulzke J, Fromm M (1997) Measurement of paracellular epithelial conductivity by conductance scanning. Pflugers Arch 434:830-840
    • (1997) Pflugers Arch , vol.434 , pp. 830-840
    • Gitter, A.H.1    Bertog, M.2    Schulzke, J.3    Fromm, M.4
  • 65
    • 0035210487 scopus 로고    scopus 로고
    • Epithelial barrier defects in ulcerative colitis: Characterization and quantification by electrophysiological imaging
    • 11729111
    • Gitter AH, Wullstein F, Fromm M, Schulzke JD (2001) Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology 121:1320-1328
    • (2001) Gastroenterology , vol.121 , pp. 1320-1328
    • Gitter, A.H.1    Wullstein, F.2    Fromm, M.3    Schulzke, J.D.4
  • 68
    • 65949112498 scopus 로고    scopus 로고
    • Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling
    • 19489925
    • Grab DJ, Nyarko E, Nikolskaia OV, Kim YV, Dumler JS (2009) Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling. Clin Microbiol Infect 15:422-426
    • (2009) Clin Microbiol Infect , vol.15 , pp. 422-426
    • Grab, D.J.1    Nyarko, E.2    Nikolskaia, O.V.3    Kim, Y.V.4    Dumler, J.S.5
  • 69
    • 0022380016 scopus 로고
    • Prostacyclin production by cultured endothelial cell monolayers exposed to step increases in shear stress
    • 3918129
    • Grabowski EF, Jaffe EA, Weksler BB (1985) Prostacyclin production by cultured endothelial cell monolayers exposed to step increases in shear stress. J Lab Clin Med 105:36-43
    • (1985) J Lab Clin Med , vol.105 , pp. 36-43
    • Grabowski, E.F.1    Jaffe, E.A.2    Weksler, B.B.3
  • 71
    • 77954644230 scopus 로고    scopus 로고
    • Biophysical methods to study tight junction permeability
    • Gunzel D, Krug SM, Rosenthal R, Fromm M (2010) Biophysical methods to study tight junction permeability. Curr Top Membr 65:39-78
    • (2010) Curr Top Membr , vol.65 , pp. 39-78
    • Gunzel, D.1    Krug, S.M.2    Rosenthal, R.3    Fromm, M.4
  • 73
    • 33947723274 scopus 로고    scopus 로고
    • The impact of glia-derived extracellular matrices on the barrier function of cerebral endothelial cells: An in vitro study
    • 17346702
    • Hartmann C, Zozulya A, Wegener J, Galla HJ (2007) The impact of glia-derived extracellular matrices on the barrier function of cerebral endothelial cells: an in vitro study. Exp Cell Res 313:1318-1325
    • (2007) Exp Cell Res , vol.313 , pp. 1318-1325
    • Hartmann, C.1    Zozulya, A.2    Wegener, J.3    Galla, H.J.4
  • 74
    • 0027971133 scopus 로고
    • Alterations in human endothelial cell morphology, proliferation and function by a macrophage-derived factor
    • 8002260
    • Heffernan M, Chance A, Hess EV, Highsmith RF, FitzGerald O (1994) Alterations in human endothelial cell morphology, proliferation and function by a macrophage-derived factor. Irish J Med Sci 163:359-365
    • (1994) Irish J Med Sci , vol.163 , pp. 359-365
    • Heffernan, M.1    Chance, A.2    Hess, E.V.3    Highsmith, R.F.4    Fitzgerald, O.5
  • 76
    • 0032776062 scopus 로고    scopus 로고
    • Vascular-endothelial-cadherin modulates endothelial monolayer permeability
    • 10341210
    • Hordijk PL, Anthony E, Mul FP, Rientsma R, Oomen LC, Roos D (1999) Vascular-endothelial-cadherin modulates endothelial monolayer permeability. J Cell Sci 112:1915-1923
    • (1999) J Cell Sci , vol.112 , pp. 1915-1923
    • Hordijk, P.L.1    Anthony, E.2    Mul, F.P.3    Rientsma, R.4    Oomen, L.C.5    Roos, D.6
  • 77
    • 38349124475 scopus 로고    scopus 로고
    • Regulation of endothelial permeability by Src kinase signaling: Vascular leakage versus transcellular transport of drugs and macromolecules
    • 3001132 17897637
    • Hu G, Place AT, Minshall RD (2008) Regulation of endothelial permeability by Src kinase signaling: vascular leakage versus transcellular transport of drugs and macromolecules. Chem Biol Interact 171:177-189
    • (2008) Chem Biol Interact , vol.171 , pp. 177-189
    • Hu, G.1    Place, A.T.2    Minshall, R.D.3
  • 79
    • 0031569517 scopus 로고    scopus 로고
    • Fluid shear stress-mediated signal transduction: How do endothelial cells transduce mechanical force into biological responses?
    • 9186580
    • Ishida T, Takahashi M, Corson MA, Berk BC (1997) Fluid shear stress-mediated signal transduction: how do endothelial cells transduce mechanical force into biological responses? Ann N Y Acad Sci 811:12-23
    • (1997) Ann N y Acad Sci , vol.811 , pp. 12-23
    • Ishida, T.1    Takahashi, M.2    Corson, M.A.3    Berk, B.C.4
  • 80
    • 84880916877 scopus 로고    scopus 로고
    • Reappraising Starling: The physiology of the microcirculation
    • 23743590
    • Jacob M, Chappell D (2013) Reappraising Starling: the physiology of the microcirculation. Curr Opin Crit Care 19:282-289
    • (2013) Curr Opin Crit Care , vol.19 , pp. 282-289
    • Jacob, M.1    Chappell, D.2
  • 81
    • 0030472464 scopus 로고    scopus 로고
    • Double-mode impedance analysis of epithelial cell monolayers cultured on shear wave resonators
    • 9035374
    • Janshoff A, Wegener J, Sieber M, Galla HJ (1996) Double-mode impedance analysis of epithelial cell monolayers cultured on shear wave resonators. Eur Biophys J 25:93-103
    • (1996) Eur Biophys J , vol.25 , pp. 93-103
    • Janshoff, A.1    Wegener, J.2    Sieber, M.3    Galla, H.J.4
  • 82
    • 0025817706 scopus 로고
    • Endothelial albumin permeability is shear dependent, time dependent, and reversible
    • 1905493
    • Jo H, Dull RO, Hollis TM, Tarbell JM (1991) Endothelial albumin permeability is shear dependent, time dependent, and reversible. Am J Physiol 260:H1992-H1996
    • (1991) Am J Physiol , vol.260
    • Jo, H.1    Dull, R.O.2    Hollis, T.M.3    Tarbell, J.M.4
  • 83
    • 0026316477 scopus 로고
    • A spectroscopic method for assessing confluence of epithelial cell cultures
    • 1767820
    • Jovov B, Wills NK, Lewis SA (1991) A spectroscopic method for assessing confluence of epithelial cell cultures. Am J Physiol 261:C1196-C1203
    • (1991) Am J Physiol , vol.261
    • Jovov, B.1    Wills, N.K.2    Lewis, S.A.3
  • 84
    • 33646498294 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase activation in endothelial cell is implicated in cell alignment and elongation induced by fluid shear stress
    • 16885066
    • Kadohama T, Akasaka N, Nishimura K, Hoshino Y, Sasajima T, Sumpio BE (2006) p38 Mitogen-activated protein kinase activation in endothelial cell is implicated in cell alignment and elongation induced by fluid shear stress. Endothelium 13:43-50
    • (2006) Endothelium , vol.13 , pp. 43-50
    • Kadohama, T.1    Akasaka, N.2    Nishimura, K.3    Hoshino, Y.4    Sasajima, T.5    Sumpio, B.E.6
  • 85
    • 18744381818 scopus 로고    scopus 로고
    • Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion
    • 137769 12434019
    • Kataoka N, Iwaki K, Hashimoto K, Mochizuki S, Ogasawara Y, Sato M, Tsujioka K, Kajiya F (2002) Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion. Proc Natl Acad Sci U S A 99:15638-15643
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15638-15643
    • Kataoka, N.1    Iwaki, K.2    Hashimoto, K.3    Mochizuki, S.4    Ogasawara, Y.5    Sato, M.6    Tsujioka, K.7    Kajiya, F.8
  • 86
    • 0036795547 scopus 로고    scopus 로고
    • Real-time impedance assay to follow the invasive activities of metastatic cells in culture
    • 12398193
    • Keese CR, Bhawe K, Wegener J, Giaever I (2002) Real-time impedance assay to follow the invasive activities of metastatic cells in culture. Biotechniques 33:842-850
    • (2002) Biotechniques , vol.33 , pp. 842-850
    • Keese, C.R.1    Bhawe, K.2    Wegener, J.3    Giaever, I.4
  • 88
    • 84878999383 scopus 로고    scopus 로고
    • Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO
    • 3681474 23640037
    • Keil JM, Liu X, Antonetti DA (2013) Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO. Invest Ophthalmol Vis Sci 54:4007-4015
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 4007-4015
    • Keil, J.M.1    Liu, X.2    Antonetti, D.A.3
  • 89
    • 77951697920 scopus 로고    scopus 로고
    • Regulation of endothelial permeability via paracellular and transcellular transport pathways
    • 20148685
    • Komarova Y, Malik AB (2010) Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol 72:463-493
    • (2010) Annu Rev Physiol , vol.72 , pp. 463-493
    • Komarova, Y.1    Malik, A.B.2
  • 91
    • 0021723174 scopus 로고
    • Rapid determination of intraepithelial resistance barriers by alternating current spectroscopy. I. Experimental procedures
    • 6522248
    • Kottra G, Fromter E (1984a) Rapid determination of intraepithelial resistance barriers by alternating current spectroscopy. I. Experimental procedures. Pflugers Arch 402:409-420
    • (1984) Pflugers Arch , vol.402 , pp. 409-420
    • Kottra, G.1    Fromter, E.2
  • 92
    • 0021709829 scopus 로고
    • Rapid determination of intraepithelial resistance barriers by alternating current spectroscopy. II. Test of model circuits and quantification of results
    • 6522249
    • Kottra G, Fromter E (1984b) Rapid determination of intraepithelial resistance barriers by alternating current spectroscopy. II. Test of model circuits and quantification of results. Pflugers Arch 402:421-432
    • (1984) Pflugers Arch , vol.402 , pp. 421-432
    • Kottra, G.1    Fromter, E.2
  • 93
    • 70449107587 scopus 로고    scopus 로고
    • Two-path impedance spectroscopy for measuring paracellular and transcellular epithelial resistance
    • 2764069 19843452
    • Krug SM, Fromm M, Gunzel D (2009) Two-path impedance spectroscopy for measuring paracellular and transcellular epithelial resistance. Biophys J 97:2202-2211
    • (2009) Biophys J , vol.97 , pp. 2202-2211
    • Krug, S.M.1    Fromm, M.2    Gunzel, D.3
  • 94
    • 0026557260 scopus 로고
    • Mechanical deformation of vessel wall and shear stress determine the basal release of endothelium-derived relaxing factor in the intact rabbit coronary vascular bed
    • 1345777
    • Lamontagne D, Pohl U, Busse R (1992) Mechanical deformation of vessel wall and shear stress determine the basal release of endothelium-derived relaxing factor in the intact rabbit coronary vascular bed. Circ Res 70:123-130
    • (1992) Circ Res , vol.70 , pp. 123-130
    • Lamontagne, D.1    Pohl, U.2    Busse, R.3
  • 95
    • 0022160653 scopus 로고
    • The elongation and orientation of cultured endothelial cells in response to shear stress
    • 4079361
    • Levesque MJ, Nerem RM (1985) The elongation and orientation of cultured endothelial cells in response to shear stress. J Biomech Eng 107:341-347
    • (1985) J Biomech Eng , vol.107 , pp. 341-347
    • Levesque, M.J.1    Nerem, R.M.2
  • 96
    • 0033560932 scopus 로고    scopus 로고
    • Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
    • 408275 10207166
    • Li S, Chen BP, Azuma N, Hu YL, Wu SZ, Sumpio BE, Shyy JY, Chien S (1999) Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress. J Clin Invest 103:1141-1150
    • (1999) J Clin Invest , vol.103 , pp. 1141-1150
    • Li, S.1    Chen, B.P.2    Azuma, N.3    Hu, Y.L.4    Wu, S.Z.5    Sumpio, B.E.6    Shyy, J.Y.7    Chien, S.8
  • 97
    • 0019857035 scopus 로고
    • Electrical properties of rabbit corneal endothelium as determined from impedance measurements
    • 1327652 7326329
    • Lim JJ, Fischbarg J (1981) Electrical properties of rabbit corneal endothelium as determined from impedance measurements. Biophys J 36:677-695
    • (1981) Biophys J , vol.36 , pp. 677-695
    • Lim, J.J.1    Fischbarg, J.2
  • 98
    • 84879782688 scopus 로고    scopus 로고
    • Molecular angiogenic events of a two-herb wound healing formula involving MAPK and Akt signaling pathways in human vascular endothelial cells
    • 23755905
    • Liu CL, Tam JC, Sanders AJ, Ko CH, Fung KP, Leung PC, Harding KG, Jiang WG, Lau CB (2013) Molecular angiogenic events of a two-herb wound healing formula involving MAPK and Akt signaling pathways in human vascular endothelial cells. Wound Repair Regen 21:579-587
    • (2013) Wound Repair Regen , vol.21 , pp. 579-587
    • Liu, C.L.1    Tam, J.C.2    Sanders, A.J.3    Ko, C.H.4    Fung, K.P.5    Leung, P.C.6    Harding, K.G.7    Jiang, W.G.8    Lau, C.B.9
  • 100
    • 0028124554 scopus 로고
    • 2 incubators cause periodic changes in cell morphology
    • 8050495
    • 2 incubators cause periodic changes in cell morphology. Exp Cell Res 213:391-397
    • (1994) Exp Cell Res , vol.213 , pp. 391-397
    • Lo, C.M.1    Keese, C.R.2    Giaever, I.3
  • 101
    • 0033179025 scopus 로고    scopus 로고
    • Cell-substrate contact: Another factor may influence transepithelial electrical resistance of cell layers cultured on permeable filters
    • 10413610
    • Lo CM, Keese CR, Giaever I (1999) Cell-substrate contact: another factor may influence transepithelial electrical resistance of cell layers cultured on permeable filters. Exp Cell Res 250:576-580
    • (1999) Exp Cell Res , vol.250 , pp. 576-580
    • Lo, C.M.1    Keese, C.R.2    Giaever, I.3
  • 102
    • 0035984809 scopus 로고    scopus 로고
    • Predicting blood-brain barrier permeability of drugs: Evaluation of different in vitro assays
    • 12164375
    • Lohmann C, Huwel S, Galla HJ (2002) Predicting blood-brain barrier permeability of drugs: evaluation of different in vitro assays. J Drug Target 10:263-276
    • (2002) J Drug Target , vol.10 , pp. 263-276
    • Lohmann, C.1    Huwel, S.2    Galla, H.J.3
  • 104
    • 80053558294 scopus 로고    scopus 로고
    • The ABC of the blood-brain barrier - Regulation of drug efflux pumps
    • 21827407
    • Mahringer A, Ott M, Reimold I, Reichel V, Fricker G (2011) The ABC of the blood-brain barrier - regulation of drug efflux pumps. Curr Pharm Des 17:2762-2770
    • (2011) Curr Pharm des , vol.17 , pp. 2762-2770
    • Mahringer, A.1    Ott, M.2    Reimold, I.3    Reichel, V.4    Fricker, G.5
  • 105
    • 0038617335 scopus 로고    scopus 로고
    • Functional analysis of tight junctions
    • 12798137
    • Matter K, Balda MS (2003) Functional analysis of tight junctions. Methods 30:228-234
    • (2003) Methods , vol.30 , pp. 228-234
    • Matter, K.1    Balda, M.S.2
  • 106
    • 34548478100 scopus 로고    scopus 로고
    • Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability
    • 17476691
    • McKenzie JA, Ridley AJ (2007) Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability. J Cell Physiol 213:221-228
    • (2007) J Cell Physiol , vol.213 , pp. 221-228
    • McKenzie, J.A.1    Ridley, A.J.2
  • 107
    • 19944431688 scopus 로고    scopus 로고
    • Effects of flow patterns on the localization and expression of VE-cadherin at vascular endothelial cell junctions: In vivo and in vitro investigations
    • 15637443
    • Miao H, Hu YL, Shiu YT, Yuan S, Zhao Y, Kaunas R, Wang Y, Jin G, Usami S, Chien S (2005) Effects of flow patterns on the localization and expression of VE-cadherin at vascular endothelial cell junctions: in vivo and in vitro investigations. J Vasc Res 42:77-89
    • (2005) J Vasc Res , vol.42 , pp. 77-89
    • Miao, H.1    Hu, Y.L.2    Shiu, Y.T.3    Yuan, S.4    Zhao, Y.5    Kaunas, R.6    Wang, Y.7    Jin, G.8    Usami, S.9    Chien, S.10
  • 109
    • 84878349555 scopus 로고    scopus 로고
    • Label-free monitoring of cell-based assays: Combining impedance analysis with SPR for multiparametric cell profiling
    • 23711901
    • Michaelis S, Wegener J, Robelek R (2013) Label-free monitoring of cell-based assays: combining impedance analysis with SPR for multiparametric cell profiling. Biosens Bioelectron 49:63-70
    • (2013) Biosens Bioelectron , vol.49 , pp. 63-70
    • Michaelis, S.1    Wegener, J.2    Robelek, R.3
  • 110
    • 84896694765 scopus 로고    scopus 로고
    • Signaling pathways that regulate basal ABC transporter activity at the blood-brain barrier
    • (in press)
    • Miller DS, Cannon RE (2013) Signaling pathways that regulate basal ABC transporter activity at the blood-brain barrier. Curr Pharm Des (in press)
    • (2013) Curr Pharm des
    • Miller, D.S.1    Cannon, R.E.2
  • 112
    • 84872310637 scopus 로고    scopus 로고
    • Laminar shear stress induces the expression of aquaporin 1 in endothelial cells involved in wound healing
    • 23220481
    • Mun GI, Jang SI, Boo YC (2013) Laminar shear stress induces the expression of aquaporin 1 in endothelial cells involved in wound healing. Biochem Biophys Res Commun 430:554-559
    • (2013) Biochem Biophys Res Commun , vol.430 , pp. 554-559
    • Mun, G.I.1    Jang, S.I.2    Boo, Y.C.3
  • 113
    • 33750812262 scopus 로고    scopus 로고
    • Involvement of SA channels in orienting response of cultured endothelial cells to cyclic stretch
    • 9612360
    • Naruse K, Yamada T, Sokabe M (1998) Involvement of SA channels in orienting response of cultured endothelial cells to cyclic stretch. Am J Physiol 274:H1532-H1538
    • (1998) Am J Physiol , vol.274
    • Naruse, K.1    Yamada, T.2    Sokabe, M.3
  • 114
    • 39849099174 scopus 로고    scopus 로고
    • Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1
    • 3071982 18285569
    • Nauli SM, Kawanabe Y, Kaminski JJ, Pearce WJ, Ingber DE, Zhou J (2008) Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation 117:1161-1171
    • (2008) Circulation , vol.117 , pp. 1161-1171
    • Nauli, S.M.1    Kawanabe, Y.2    Kaminski, J.J.3    Pearce, W.J.4    Ingber, D.E.5    Zhou, J.6
  • 116
    • 0033578742 scopus 로고    scopus 로고
    • Transient and steady-state effects of shear stress on endothelial cell adherens junctions
    • 10488053
    • Noria S, Cowan DB, Gotlieb AI, Langille BL (1999) Transient and steady-state effects of shear stress on endothelial cell adherens junctions. Circ Res 85:504-514
    • (1999) Circ Res , vol.85 , pp. 504-514
    • Noria, S.1    Cowan, D.B.2    Gotlieb, A.I.3    Langille, B.L.4
  • 118
    • 62649107805 scopus 로고    scopus 로고
    • Use of electric cell-substrate impedance sensing to assess in vitro cytotoxicity
    • 2668605 19230649
    • Opp D, Wafula B, Lim J, Huang E, Lo JC, Lo CM (2009) Use of electric cell-substrate impedance sensing to assess in vitro cytotoxicity. Biosens Bioelectron 24:2625-2629
    • (2009) Biosens Bioelectron , vol.24 , pp. 2625-2629
    • Opp, D.1    Wafula, B.2    Lim, J.3    Huang, E.4    Lo, J.C.5    Lo, C.M.6
  • 120
    • 0001706901 scopus 로고
    • Impedance of rough capacitive electrodes
    • Pajkossy T (1994) Impedance of rough capacitive electrodes. J Electroanal Chem 364:111-125
    • (1994) J Electroanal Chem , vol.364 , pp. 111-125
    • Pajkossy, T.1
  • 121
    • 29144473613 scopus 로고    scopus 로고
    • Shear stress regulates HUVEC hydraulic conductivity by occludin phosphorylation
    • 16341921
    • Pang Z, Antonetti DA, Tarbell JM (2005) Shear stress regulates HUVEC hydraulic conductivity by occludin phosphorylation. Ann Biomed Eng 33:1536-1545
    • (2005) Ann Biomed Eng , vol.33 , pp. 1536-1545
    • Pang, Z.1    Antonetti, D.A.2    Tarbell, J.M.3
  • 123
    • 0034844297 scopus 로고    scopus 로고
    • Update on pulmonary edema: The role and regulation of endothelial barrier function
    • 11572478
    • Patterson CE, Lum H (2001) Update on pulmonary edema: the role and regulation of endothelial barrier function. Endothelium 8:75-105
    • (2001) Endothelium , vol.8 , pp. 75-105
    • Patterson, C.E.1    Lum, H.2
  • 124
    • 0034012304 scopus 로고    scopus 로고
    • Spatial variations in endothelial barrier function in disturbed flows in vitro
    • 10666077
    • Phelps JE, DePaola N (2000) Spatial variations in endothelial barrier function in disturbed flows in vitro. Am J Physiol Heart Circ Physiol 278:H469-H476
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Phelps, J.E.1    Depaola, N.2
  • 126
    • 0019631483 scopus 로고
    • Barrier function of epithelia
    • 7032321
    • Powell DW (1981) Barrier function of epithelia. Am J Physiol 241:G275-G288
    • (1981) Am J Physiol , vol.241
    • Powell, D.W.1
  • 127
    • 35348872064 scopus 로고    scopus 로고
    • Molecular determinants of endothelial transcytosis and their role in endothelial permeability
    • 17644753
    • Predescu SA, Predescu DN, Malik AB (2007) Molecular determinants of endothelial transcytosis and their role in endothelial permeability. Am J Physiol Lung Cell Mol Physiol 293:L823-L842
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Predescu, S.A.1    Predescu, D.N.2    Malik, A.B.3
  • 128
    • 21144457363 scopus 로고    scopus 로고
    • Roles of hemodynamic forces in vascular cell differentiation
    • 16078617
    • Riha GM, Lin PH, Lumsden AB, Yao Q, Chen C (2005) Roles of hemodynamic forces in vascular cell differentiation. Ann Biomed Eng 33:772-779
    • (2005) Ann Biomed Eng , vol.33 , pp. 772-779
    • Riha, G.M.1    Lin, P.H.2    Lumsden, A.B.3    Yao, Q.4    Chen, C.5
  • 129
    • 71849102692 scopus 로고    scopus 로고
    • Label-free and time-resolved measurements of cell volume changes by surface plasmon resonance (SPR) spectroscopy
    • 19818594
    • Robelek R, Wegener J (2010) Label-free and time-resolved measurements of cell volume changes by surface plasmon resonance (SPR) spectroscopy. Biosens Bioelectron 25:1221-1224
    • (2010) Biosens Bioelectron , vol.25 , pp. 1221-1224
    • Robelek, R.1    Wegener, J.2
  • 130
    • 34047237922 scopus 로고    scopus 로고
    • Real-time measurement of PMA-induced cellular alterations by microelectrode array-based impedance spectroscopy
    • 17068960
    • Rothermel A, Nieber M, Muller J, Wolf P, Schmidt M, Robitzki AA (2006) Real-time measurement of PMA-induced cellular alterations by microelectrode array-based impedance spectroscopy. Biotechniques 41:445-450
    • (2006) Biotechniques , vol.41 , pp. 445-450
    • Rothermel, A.1    Nieber, M.2    Muller, J.3    Wolf, P.4    Schmidt, M.5    Robitzki, A.A.6
  • 131
    • 77955275646 scopus 로고    scopus 로고
    • Role of p120-catenin in the morphological changes of endothelial cells exposed to fluid shear stress
    • 20599710
    • Sakamoto N, Segawa K, Kanzaki M, Ohashi T, Sato M (2010) Role of p120-catenin in the morphological changes of endothelial cells exposed to fluid shear stress. Biochem Biophys Res Commun 398:426-432
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 426-432
    • Sakamoto, N.1    Segawa, K.2    Kanzaki, M.3    Ohashi, T.4    Sato, M.5
  • 132
    • 67049160811 scopus 로고    scopus 로고
    • New aspects of glomerular filtration barrier structure and function: Five layers (at least) not three
    • 19365184
    • Salmon AH, Neal CR, Harper SJ (2009) New aspects of glomerular filtration barrier structure and function: five layers (at least) not three. Curr Opin Nephrol Hypertens 18:197-205
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , pp. 197-205
    • Salmon, A.H.1    Neal, C.R.2    Harper, S.J.3
  • 133
    • 0032437543 scopus 로고    scopus 로고
    • Structural and functional aspects of intercellular junctions in vascular endothelium
    • 9879442
    • Schnittler HJ (1998) Structural and functional aspects of intercellular junctions in vascular endothelium. Basic Res Cardiol 93 (Suppl 3):30-39
    • (1998) Basic Res Cardiol , vol.93 , Issue.SUPPL.. 3 , pp. 30-39
    • Schnittler, H.J.1
  • 134
    • 0027218134 scopus 로고
    • Improved in vitro rheological system for studying the effect of fluid shear stress on cultured cells
    • 8338136
    • Schnittler HJ, Franke RP, Akbay U, Mrowietz C, Drenckhahn D (1993) Improved in vitro rheological system for studying the effect of fluid shear stress on cultured cells. Am J Physiol 265:C289-C298
    • (1993) Am J Physiol , vol.265
    • Schnittler, H.J.1    Franke, R.P.2    Akbay, U.3    Mrowietz, C.4    Drenckhahn, D.5
  • 136
    • 77956486698 scopus 로고    scopus 로고
    • Label-free whole-cell assays: Expanding the scope of GPCR screening
    • 20601093
    • Scott CW, Peters MF (2010) Label-free whole-cell assays: expanding the scope of GPCR screening. Drug Discov Today 15:704-716
    • (2010) Drug Discov Today , vol.15 , pp. 704-716
    • Scott, C.W.1    Peters, M.F.2
  • 139
    • 13544264582 scopus 로고    scopus 로고
    • Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells
    • 15707572
    • Shikata Y, Rios A, Kawkitinarong K, DePaola N, Garcia JG, Birukov KG (2005) Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells. Exp Cell Res 304:40-49
    • (2005) Exp Cell Res , vol.304 , pp. 40-49
    • Shikata, Y.1    Rios, A.2    Kawkitinarong, K.3    Depaola, N.4    Garcia, J.G.5    Birukov, K.G.6
  • 140
    • 0000468258 scopus 로고
    • Albumin permeability and electrical resistance as means of assessing endothelial monolayer integrity in vitro
    • Sill H, Butler C, Hollis T, Tarbell J (1992) Albumin permeability and electrical resistance as means of assessing endothelial monolayer integrity in vitro. J Tissue Cult Methods 14:253-257
    • (1992) J Tissue Cult Methods , vol.14 , pp. 253-257
    • Sill, H.1    Butler, C.2    Hollis, T.3    Tarbell, J.4
  • 142
    • 33846882646 scopus 로고    scopus 로고
    • Brain oedema in focal ischaemia: Molecular pathophysiology and theoretical implications
    • 2725365 17303532
    • Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V (2007) Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol 6:258-268
    • (2007) Lancet Neurol , vol.6 , pp. 258-268
    • Simard, J.M.1    Kent, T.A.2    Chen, M.3    Tarasov, K.V.4    Gerzanich, V.5
  • 143
    • 0016724876 scopus 로고
    • Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature
    • 1202025
    • Simionescu M, Simionescu N, Palade GE (1975) Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature. J Cell Biol 67:863-885
    • (1975) J Cell Biol , vol.67 , pp. 863-885
    • Simionescu, M.1    Simionescu, N.2    Palade, G.E.3
  • 144
    • 0017229099 scopus 로고
    • Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins
    • 1030708
    • Simionescu M, Simionescu N, Palade GE (1976) Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins. J Cell Biol 68:705-723
    • (1976) J Cell Biol , vol.68 , pp. 705-723
    • Simionescu, M.1    Simionescu, N.2    Palade, G.E.3
  • 145
    • 0031453573 scopus 로고    scopus 로고
    • Impedance and shear wave resonance analysis of ligand-receptor interactions at functionalized surfaces and of cell monolayers
    • 9421888
    • Steinem C, Janshoff A, Wegener J, Ulrich WP, Willenbrink W, Sieber M, Galla HJ (1997) Impedance and shear wave resonance analysis of ligand-receptor interactions at functionalized surfaces and of cell monolayers. Biosens Bioelectron 12:787-808
    • (1997) Biosens Bioelectron , vol.12 , pp. 787-808
    • Steinem, C.1    Janshoff, A.2    Wegener, J.3    Ulrich, W.P.4    Willenbrink, W.5    Sieber, M.6    Galla, H.J.7
  • 146
    • 0022553592 scopus 로고
    • Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers
    • 1888144 2421578
    • Stolpen AH, Guinan EC, Fiers W, Pober JS (1986) Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers. Am J Pathol 123:16-24
    • (1986) Am J Pathol , vol.123 , pp. 16-24
    • Stolpen, A.H.1    Guinan, E.C.2    Fiers, W.3    Pober, J.S.4
  • 147
    • 79960439320 scopus 로고    scopus 로고
    • Impedance analysis of adherent cells after in situ electroporation: Non-invasive monitoring during intracellular manipulations
    • 21684144
    • Stolwijk JA, Hartmann C, Balani P, Albermann S, Keese CR, Giaever I, Wegener J (2011) Impedance analysis of adherent cells after in situ electroporation: non-invasive monitoring during intracellular manipulations. Biosens Bioelectron 26:4720-4727
    • (2011) Biosens Bioelectron , vol.26 , pp. 4720-4727
    • Stolwijk, J.A.1    Hartmann, C.2    Balani, P.3    Albermann, S.4    Keese, C.R.5    Giaever, I.6    Wegener, J.7
  • 148
    • 79960367186 scopus 로고    scopus 로고
    • Nonmuscle myosin light-chain kinase deficiency attenuates atherosclerosis in apolipoprotein E-deficient mice via reduced endothelial barrier dysfunction and monocyte migration
    • 3136817 21670231
    • Sun C, Wu MH, Yuan SY (2011) Nonmuscle myosin light-chain kinase deficiency attenuates atherosclerosis in apolipoprotein E-deficient mice via reduced endothelial barrier dysfunction and monocyte migration. Circulation 124:48-57
    • (2011) Circulation , vol.124 , pp. 48-57
    • Sun, C.1    Wu, M.H.2    Yuan, S.Y.3
  • 149
    • 84866625277 scopus 로고    scopus 로고
    • A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity
    • 3482138 22904271
    • Sun C, Wu MH, Lee ES, Yuan SY (2012) A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity. Arterioscler Thromb Vasc Biol 32:2444-2451
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2444-2451
    • Sun, C.1    Wu, M.H.2    Lee, E.S.3    Yuan, S.Y.4
  • 152
    • 0031001489 scopus 로고    scopus 로고
    • Mechanotransduction in endothelial cells: Temporal signaling events in response to shear stress
    • 9226303
    • Takahashi M, Ishida T, Traub O, Corson MA, Berk BC (1997) Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress. J Vasc Res 34:212-219
    • (1997) J Vasc Res , vol.34 , pp. 212-219
    • Takahashi, M.1    Ishida, T.2    Traub, O.3    Corson, M.A.4    Berk, B.C.5
  • 153
    • 77954341974 scopus 로고    scopus 로고
    • Shear stress and the endothelial transport barrier
    • 2915475 20543206
    • Tarbell JM (2010) Shear stress and the endothelial transport barrier. Cardiovasc Res 87:320-330
    • (2010) Cardiovasc Res , vol.87 , pp. 320-330
    • Tarbell, J.M.1
  • 154
    • 84872596894 scopus 로고    scopus 로고
    • Effect of the glycocalyx layer on transmission of interstitial flow shear stress to embedded cells
    • 3394897 22411016
    • Tarbell JM, Shi ZD (2013) Effect of the glycocalyx layer on transmission of interstitial flow shear stress to embedded cells. Biomech Model Mechanobiol 12:111-121
    • (2013) Biomech Model Mechanobiol , vol.12 , pp. 111-121
    • Tarbell, J.M.1    Shi, Z.D.2
  • 155
    • 0032788446 scopus 로고    scopus 로고
    • Effect of pressure on hydraulic conductivity of endothelial monolayers: Role of endothelial cleft shear stress
    • 10409584
    • Tarbell JM, Demaio L, Zaw MM (1999) Effect of pressure on hydraulic conductivity of endothelial monolayers: role of endothelial cleft shear stress. J Appl Physiol 87:261-268
    • (1999) J Appl Physiol , vol.87 , pp. 261-268
    • Tarbell, J.M.1    Demaio, L.2    Zaw, M.M.3
  • 156
    • 84884777032 scopus 로고    scopus 로고
    • Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system
    • 3715459 23874198
    • Taylor SL, Wahl-Jensen V, Copeland AM, Jahrling PB, Schmaljohn CS (2013) Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system. PLoS Pathogens 9:e1003470
    • (2013) PLoS Pathogens , vol.9 , pp. 1003470
    • Taylor, S.L.1    Wahl-Jensen, V.2    Copeland, A.M.3    Jahrling, P.B.4    Schmaljohn, C.S.5
  • 157
    • 53249156455 scopus 로고    scopus 로고
    • What underlies endothelial shear sensing? the matrix, of course
    • 2732584 18796640
    • Terada LS (2008) What underlies endothelial shear sensing? The matrix, of course. Circ Res 103:562-564
    • (2008) Circ Res , vol.103 , pp. 562-564
    • Terada, L.S.1
  • 159
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
    • 9598824
    • Traub O, Berk BC (1998) Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 18:677-685
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 160
    • 0034717271 scopus 로고    scopus 로고
    • Role of nitric oxide in human pulmonary microvascular endothelial cell adhesion
    • 10896023
    • Tsukahara H, Noiri E, Jiang MZ, Hiraoka M, Mayumi M (2000) Role of nitric oxide in human pulmonary microvascular endothelial cell adhesion. Life Sci 67:1-11
    • (2000) Life Sci , vol.67 , pp. 1-11
    • Tsukahara, H.1    Noiri, E.2    Jiang, M.Z.3    Hiraoka, M.4    Mayumi, M.5
  • 161
    • 0026581885 scopus 로고
    • Flows of liquid and electrical current through monolayers of cultured bovine arterial endothelium
    • 1176064
    • Turner MR (1992) Flows of liquid and electrical current through monolayers of cultured bovine arterial endothelium. J Physiol (Lond) 449:1-20
    • (1992) J Physiol (Lond) , vol.449 , pp. 1-20
    • Turner, M.R.1
  • 162
    • 0036060369 scopus 로고    scopus 로고
    • Regulation of VE-cadherin linkage to the cytoskeleton in endothelial cells exposed to fluid shear stress
    • 11822879
    • Ukropec JA, Hollinger MK, Woolkalis MJ (2002) Regulation of VE-cadherin linkage to the cytoskeleton in endothelial cells exposed to fluid shear stress. Exp Cell Res 273:240-247
    • (2002) Exp Cell Res , vol.273 , pp. 240-247
    • Ukropec, J.A.1    Hollinger, M.K.2    Woolkalis, M.J.3
  • 163
    • 77955661133 scopus 로고    scopus 로고
    • Visualizing vascular permeability and lymphatic drainage using labeled serum albumin
    • 2921845 20512410
    • Vandoorne K, Addadi Y, Neeman M (2010) Visualizing vascular permeability and lymphatic drainage using labeled serum albumin. Angiogenesis 13:75-85
    • (2010) Angiogenesis , vol.13 , pp. 75-85
    • Vandoorne, K.1    Addadi, Y.2    Neeman, M.3
  • 164
    • 0036319341 scopus 로고    scopus 로고
    • Aquaporin water channels and endothelial cell function
    • 1570747 12162729
    • Verkman AS (2002) Aquaporin water channels and endothelial cell function. J Anat 200:617-627
    • (2002) J Anat , vol.200 , pp. 617-627
    • Verkman, A.S.1
  • 165
    • 33645512266 scopus 로고    scopus 로고
    • Aquaporins in endothelia
    • 16508658
    • Verkman AS (2006) Aquaporins in endothelia. Kidney Int 69:1120-1123
    • (2006) Kidney Int , vol.69 , pp. 1120-1123
    • Verkman, A.S.1
  • 166
    • 38549128935 scopus 로고    scopus 로고
    • VE-cadherin: The major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
    • 18162609
    • Vestweber D (2008) VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler Thromb Vasc Biol 28:223-232
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 223-232
    • Vestweber, D.1
  • 167
    • 39849104321 scopus 로고    scopus 로고
    • Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis
    • 17961505
    • Wallez Y, Huber P (2008) Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. Biochim Biophys Acta 1778:794-809
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 794-809
    • Wallez, Y.1    Huber, P.2
  • 168
    • 80051931770 scopus 로고    scopus 로고
    • Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels
    • 21302304
    • Walsh TG, Murphy RP, Fitzpatrick P, Rochfort KD, Guinan AF, Murphy A, Cummins PM (2011) Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels. J Cell Physiol 226:3053-3063
    • (2011) J Cell Physiol , vol.226 , pp. 3053-3063
    • Walsh, T.G.1    Murphy, R.P.2    Fitzpatrick, P.3    Rochfort, K.D.4    Guinan, A.F.5    Murphy, A.6    Cummins, P.M.7
  • 169
    • 77952616790 scopus 로고    scopus 로고
    • Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules
    • 2886649 20363882
    • Warboys CM, Eric Berson R, Mann GE, Pearson JD, Weinberg PD (2010) Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules. Am J Physiol Heart Circ Physiol 298:H1850-H1856
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Warboys, C.M.1    Eric Berson, R.2    Mann, G.E.3    Pearson, J.D.4    Weinberg, P.D.5
  • 170
  • 171
    • 0030578217 scopus 로고    scopus 로고
    • Impedance analysis of epithelial and endothelial cell monolayers cultured on gold surfaces
    • 8844323
    • Wegener J, Sieber M, Galla HJ (1996) Impedance analysis of epithelial and endothelial cell monolayers cultured on gold surfaces. J Biochem Biophys Methods 32:151-170
    • (1996) J Biochem Biophys Methods , vol.32 , pp. 151-170
    • Wegener, J.1    Sieber, M.2    Galla, H.J.3
  • 172
    • 1242281564 scopus 로고    scopus 로고
    • Use of electrochemical impedance measurements to monitor beta-adrenergic stimulation of bovine aortic endothelial cells
    • 10370072
    • Wegener J, Zink S, Rosen P, Galla H (1999) Use of electrochemical impedance measurements to monitor beta-adrenergic stimulation of bovine aortic endothelial cells. Pflugers Arch 437:925-934
    • (1999) Pflugers Arch , vol.437 , pp. 925-934
    • Wegener, J.1    Zink, S.2    Rosen, P.3    Galla, H.4
  • 173
    • 0033981418 scopus 로고    scopus 로고
    • Barrier function of porcine choroid plexus epithelial cells is modulated by cAMP-dependent pathways in vitro
    • 10627315
    • Wegener J, Hakvoort A, Galla HJ (2000a) Barrier function of porcine choroid plexus epithelial cells is modulated by cAMP-dependent pathways in vitro. Brain Res 853:115-124
    • (2000) Brain Res , vol.853 , pp. 115-124
    • Wegener, J.1    Hakvoort, A.2    Galla, H.J.3
  • 174
    • 0034714440 scopus 로고    scopus 로고
    • Electric cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces
    • 10942588
    • Wegener J, Keese CR, Giaever I (2000b) Electric cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces. Exp Cell Res 259:158-166
    • (2000) Exp Cell Res , vol.259 , pp. 158-166
    • Wegener, J.1    Keese, C.R.2    Giaever, I.3
  • 175
    • 6344282698 scopus 로고    scopus 로고
    • Automated multi-well device to measure transepithelial electrical resistances under physiological conditions
    • 15517971
    • Wegener J, Abrams D, Willenbrink W, Galla HJ, Janshoff A (2004) Automated multi-well device to measure transepithelial electrical resistances under physiological conditions. Biotechniques 37:590-597
    • (2004) Biotechniques , vol.37 , pp. 590-597
    • Wegener, J.1    Abrams, D.2    Willenbrink, W.3    Galla, H.J.4    Janshoff, A.5
  • 176
    • 74249124138 scopus 로고    scopus 로고
    • Different pathways with distinct properties conduct dilations in the microcirculation in vivo
    • Wit C de (2010) Different pathways with distinct properties conduct dilations in the microcirculation in vivo. Cardiovasc Res 85:604-613
    • (2010) Cardiovasc Res , vol.85 , pp. 604-613
    • De Wit, C.1
  • 177
    • 0037731922 scopus 로고    scopus 로고
    • Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases
    • 2172912 12719476
    • Wojciak-Stothard B, Ridley AJ (2003) Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J Cell Biol 161:429-439
    • (2003) J Cell Biol , vol.161 , pp. 429-439
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 178
    • 77649108609 scopus 로고    scopus 로고
    • Disturbed flow-enhanced endothelial turnover in atherosclerosis
    • 20211434
    • Xu Q (2009) Disturbed flow-enhanced endothelial turnover in atherosclerosis. Trends Cardiovasc Med 19:191-195
    • (2009) Trends Cardiovasc Med , vol.19 , pp. 191-195
    • Xu, Q.1
  • 179
    • 34547899189 scopus 로고    scopus 로고
    • Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress
    • 17468337
    • Yao Y, Rabodzey A, Dewey CF Jr (2007) Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress. Am J Physiol Heart Circ Physiol 293:H1023-H1030
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Yao, Y.1    Rabodzey, A.2    Dewey, Jr.C.F.3
  • 180
    • 22144480136 scopus 로고    scopus 로고
    • LPA and S1P increase corneal epithelial and endothelial cell transcellular resistance
    • 15914605
    • Yin F, Watsky MA (2005) LPA and S1P increase corneal epithelial and endothelial cell transcellular resistance. Invest Ophthalmol Vis Sci 46:1927-1933
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 1927-1933
    • Yin, F.1    Watsky, M.A.2
  • 182
    • 80053265913 scopus 로고    scopus 로고
    • Impedance-based surveillance of transient permeability changes in coronary endothelial monolayers after exposure to ionizing radiation
    • 21861763
    • Young EF, Smilenov LB (2011) Impedance-based surveillance of transient permeability changes in coronary endothelial monolayers after exposure to ionizing radiation. Radiat Res 176:415-424
    • (2011) Radiat Res , vol.176 , pp. 415-424
    • Young, E.F.1    Smilenov, L.B.2
  • 183
    • 76149138872 scopus 로고    scopus 로고
    • Technique for real-time measurements of endothelial permeability in a microfluidic membrane chip using laser-induced fluorescence detection
    • 20050596
    • Young EW, Watson MW, Srigunapalan S, Wheeler AR, Simmons CA (2010) Technique for real-time measurements of endothelial permeability in a microfluidic membrane chip using laser-induced fluorescence detection. Anal Chem 82:808-816
    • (2010) Anal Chem , vol.82 , pp. 808-816
    • Young, E.W.1    Watson, M.W.2    Srigunapalan, S.3    Wheeler, A.R.4    Simmons, C.A.5
  • 184
    • 0027168741 scopus 로고
    • Regulation of endothelial permeability by beta-adrenoceptor agonists: Contribution of beta 1- and beta 2-adrenoceptors
    • 8103357
    • Zink S, Rosen P, Sackmann B, Lemoine H (1993) Regulation of endothelial permeability by beta-adrenoceptor agonists: contribution of beta 1- and beta 2-adrenoceptors. Biochim Biophys Acta 1178:286-298
    • (1993) Biochim Biophys Acta , vol.1178 , pp. 286-298
    • Zink, S.1    Rosen, P.2    Sackmann, B.3    Lemoine, H.4


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