Cell cycle inhibitors for the treatment of NSCLC

Expert Opinion on Pharmacotherapy

Volumn 15, Issue 7, 2014, Pages 991-1004

  Shcherba, Marina ^a   Liang, Yuanxin ^a   Fernandes, David ^a   Perez Soler, Roman ^a   Cheng, Haiying ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Aurora kinase; Cell cycle inhibitor; Cyclin dependent kinase; Lung cancer; Polo like kinase

Indexed keywords

4 (3 DIMETHYLAMINOPROPYLAMINO) 2 (4 METHOXYSTYRYL)QUINAZOLINE; 4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE; 5 (3 FLUOROPHENYL) N (3 PIPERIDINYL) 3 UREIDO 2 THIOPHENECARBOXAMIDE; ALISERTIB; ANTINEOPLASTIC AGENT; AURORA KINASE; AURORA KINASE INHIBITOR; AZD 5438; AZD 6738; BIOLOGICAL MARKER; CELL CYCLE INHIBITOR; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; DINACICLIB; ENMD 2076; FLAVOPIRIDOL; INDISULAM; LY 2606368; MILCICLIB; PALBOCICLIB; PF 00477736; POLO LIKE KINASE; RABUSERTIB; ROSCOVITINE; SCH 900776; TAK 901; TOZASERTIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOLASERTIB;

ANOREXIA; ANTINEOPLASTIC ACTIVITY; ASTHENIA; ATAXIA; BONE MARROW SUPPRESSION; BRADYCARDIA; CANCER CONTROL; CARDIOMYOPATHY; CELL CYCLE REGULATION; CELL DIVISION; DECREASED APPETITE; DEHYDRATION; DIARRHEA; DRUG TARGETING; DRUG TOLERABILITY; ELECTROLYTE DISTURBANCE; FATIGUE; FEBRILE NEUTROPENIA; HEART ATRIUM FIBRILLATION; HEART INFARCTION; HUMAN; HYPERTENSION; HYPERURICEMIA; HYPOKALEMIA; LEUKOPENIA; LUNG NON SMALL CELL CANCER; MUCOSA INFLAMMATION; NAUSEA; NEUTROPENIA; PATIENT SELECTION; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PNEUMONIA; RASH; REVIEW; SIDE EFFECT; SUPRAVENTRICULAR TACHYCARDIA; THROMBOCYTOPENIA; TREMOR; VEIN THROMBOSIS; VOMITING;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; DRUG DISCOVERY; HUMANS; LUNG; LUNG NEOPLASMS; MOLECULAR TARGETED THERAPY; PROTEIN KINASE INHIBITORS;

EID: 84899451284     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2014.902935     Document Type: Review

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