In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762

Clinical Cancer Research

Volumn 16, Issue 7, 2010, Pages 2076-2084

  Mitchell, James B ^a   Choudhuri, Rajani ^a   Fabre, Kristin ^a   Sowers, Anastasia L ^a   Citrin, Deborah ^a   Zabludoff, Sonya D ^b   Cook, John A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AZD 7762; CYCLIN B; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIZATION; TUMOR CELL; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; CELLS, CULTURED; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; G2 PHASE; HT29 CELLS; HUMANS; MICE; MICE, NUDE; MITOTIC INDEX; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; THIOPHENES; UREA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77950650401     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-3277     Document Type: Article

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