Tnfaip8 l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model

Journal of Neurochemistry

Volumn 129, Issue 3, 2014, Pages 527-538

  Ha, Ji Young ^a   Kim, Ji Soo ^a   Kang, Young Hee ^a   Bok, Eugene ^b   Kim, Yoon Seong ^b   Son, Jin H ^a,c  

^a Seoul National University   (South Korea)

^b UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^c Ewha Womans University   (South Korea)

Author keywords

autophagy; dopamine neuron; mTOR; oxidative stress; Parkinson's disease; TSC2

Indexed keywords

F BOX PROTEIN; FBXW5 PROTEIN, HUMAN; SIGNAL PEPTIDE; TIPE1 PROTEIN, HUMAN; TUBERIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; ARTICLE; AUTOPHAGY; CELL LINE; CONFOCAL MICROSCOPY; DISEASE MODEL; DNA MICROARRAY; DOPAMINERGIC NERVE CELL; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; MTOR; OXIDATIVE STRESS; PARKINSON DISEASE; PARKINSONISM; PHYSIOLOGY; PROTEIN BINDING; RAT; TSC2; WESTERN BLOTTING;

AUTOPHAGY; DOPAMINE NEURON; MTOR; OXIDATIVE STRESS; PARKINSON'S DISEASE; TSC2;

ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; F-BOX PROTEINS; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; PROTEIN BINDING; RATS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84899423719     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12643     Document Type: Article

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