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Volumn 9, Issue 4, 2014, Pages

Synthesis and propagation of complement C3 by microglia/monocytes in the aging retina

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; COMPLEMENT COMPONENT C3; CXCL11 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLIAL FIBRILLARY ACIDIC PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; PLASMA PROTEIN; PROTEIN IBA1; UNCLASSIFIED DRUG; CHEMOKINE;

EID: 84899420731     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093343     Document Type: Article
Times cited : (44)

References (76)
  • 3
    • 0038708118 scopus 로고    scopus 로고
    • Age-related macular degeneration: Etiology, pathogenesis, and therapeutic strategies
    • DOI 10.1016/S0039-6257(03)00030-4
    • Ambati J, Ambati BK, Yoo SH, Ianchulev S, Adamis AP (2003) Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies. Surv Ophthalmol 48: 257-293. (Pubitemid 36553096)
    • (2003) Survey of Ophthalmology , vol.48 , Issue.3 , pp. 257-293
    • Ambati, J.1    Ambati, B.K.2    Yoo, S.H.3    Ianchulev, S.4    Adamis, A.P.5
  • 4
    • 79956053371 scopus 로고    scopus 로고
    • Age-related macular degeneration and the other double helix. The Cogan Lecture
    • Ambati J (2011) Age-related macular degeneration and the other double helix. The Cogan Lecture. Invest Ophthalmol Vis Sci 52: 2165-2169.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 2165-2169
    • Ambati, J.1
  • 5
    • 65249101367 scopus 로고    scopus 로고
    • Forecasting age-related macular degeneration through the year 2050: The potential impact of new treatments
    • Rein DB, Wittenborn JS, Zhang X, Honeycutt AA, Lesesne SB, et al. (2009) Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments. Arch Ophthalmol 127: 533-540.
    • (2009) Arch Ophthalmol , vol.127 , pp. 533-540
    • Rein, D.B.1    Wittenborn, J.S.2    Zhang, X.3    Honeycutt, A.A.4    Lesesne, S.B.5
  • 7
    • 0022871473 scopus 로고
    • Age-related macular degeneration: Ultrastructural studies of the relationship of leucocytes to angiogenesis
    • DOI 10.1007/BF02155808
    • Penfold PL, Provis JM, Billson FA (1987) Age-related macular degeneration: ultrastructural studies of the relationship of leucocytes to angiogenesis. Graefes Arch Clin Exp Ophthalmol 225: 70-76. (Pubitemid 17017857)
    • (1986) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.225 , Issue.1 , pp. 70-76
    • Penfold, P.L.1    Provis, J.M.2    Billson, F.A.3
  • 9
    • 0021187070 scopus 로고
    • An ultrastructural study of the role of leucocytes and fibroblasts in the breakdown of Bruch's membrane
    • Penfold P, Killingsworth M, Sarks S (1984) An ultrastructural study of the role of leucoytes and fibroblasts in the breakdown of Bruch's membrane. Aust J Ophthalmol 12: 23-31. (Pubitemid 14056546)
    • (1984) Australian Journal of Ophthalmology , vol.12 , Issue.1 , pp. 23-31
    • Penfold, P.1    Killingsworth, M.2    Sarks, S.3
  • 10
    • 0037375042 scopus 로고    scopus 로고
    • Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration
    • DOI 10.1016/S0014-4835(02)00332-9
    • Gupta N, Brown KE, Milam AH (2003) Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration. Exp Eye Res 76: 463-471. (Pubitemid 36299058)
    • (2003) Experimental Eye Research , vol.76 , Issue.4 , pp. 463-471
    • Gupta, N.1    Brown, K.E.2    Milam, A.H.3
  • 11
    • 77954278649 scopus 로고    scopus 로고
    • Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration
    • Cherepanoff S, McMenamin P, Gillies MC, Kettle E, Sarks SH (2009) Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration. Br J Ophthalmol 94: 918-925.
    • (2009) Br J Ophthalmol , vol.94 , pp. 918-925
    • Cherepanoff, S.1    McMenamin, P.2    Gillies, M.C.3    Kettle, E.4    Sarks, S.H.5
  • 12
    • 77249147331 scopus 로고    scopus 로고
    • The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
    • Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, et al. (2010) The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 29: 95-112.
    • (2010) Prog Retin Eye Res , vol.29 , pp. 95-112
    • Anderson, D.H.1    Radeke, M.J.2    Gallo, N.B.3    Chapin, E.A.4    Johnson, P.T.5
  • 13
    • 33144459399 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis of age-related macular degeneration
    • DOI 10.1016/j.survophthal.2005.12.001, PII S0039625705002067
    • Donoso LA, Kim D, Frost A, Callahan A, Hageman G (2006) The role of inflammation in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 51: 137-152. (Pubitemid 43269939)
    • (2006) Survey of Ophthalmology , vol.51 , Issue.2 , pp. 137-152
    • Donoso, L.A.1    Kim, D.2    Frost, A.3    Callahan, A.4    Hageman, G.5
  • 14
    • 42149156053 scopus 로고    scopus 로고
    • C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition
    • Paidassi H, Tacnet-Delorme P, Garlatti V, Darnault C, Ghebrehiwet B, et al. (2008) C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition. J Immunol 180: 2329-2338.
    • (2008) J Immunol , vol.180 , pp. 2329-2338
    • Paidassi, H.1    Tacnet-Delorme, P.2    Garlatti, V.3    Darnault, C.4    Ghebrehiwet, B.5
  • 15
    • 0035849176 scopus 로고    scopus 로고
    • Complement. Second of two parts
    • Walport MJ (2001) Complement. Second of two parts. N Engl J Med 344: 1140-1144.
    • (2001) N Engl J Med , vol.344 , pp. 1140-1144
    • Walport, M.J.1
  • 16
    • 17244379811 scopus 로고    scopus 로고
    • Complement factor H polymorphism and age-related macular degeneration
    • DOI 10.1126/science.1110189
    • Edwards AO, Ritter R, 3rd, Abel KJ, Manning A, Panhuysen C, et al. (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308: 421-424. (Pubitemid 40530082)
    • (2005) Science , vol.308 , Issue.5720 , pp. 421-424
    • Edwards, A.O.1    Ritter III, R.2    Abel, K.J.3    Manning, A.4    Panhuysen, C.5    Farrer, L.A.6
  • 20
    • 48249096770 scopus 로고    scopus 로고
    • C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes
    • Jakobsdottir J, Conley YP, Weeks DE, Ferrell RE, Gorin MB (2008) C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes. PLoS One 3: e2199.
    • (2008) PLoS One , vol.3
    • Jakobsdottir, J.1    Conley, Y.P.2    Weeks, D.E.3    Ferrell, R.E.4    Gorin, M.B.5
  • 22
    • 67649946249 scopus 로고    scopus 로고
    • Complement component 3 (C3) haplotypes and risk of advanced age-related macular degeneration
    • Park KH, Fridley BL, Ryu E, Tosakulwong N, Edwards AO (2009) Complement component 3 (C3) haplotypes and risk of advanced age-related macular degeneration. Invest Ophthalmol Vis Sci 50: 3386-3393.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 3386-3393
    • Park, K.H.1    Fridley, B.L.2    Ryu, E.3    Tosakulwong, N.4    Edwards, A.O.5
  • 23
    • 34748819371 scopus 로고    scopus 로고
    • Variation in complement factor 3 is associated with risk of age-related macular degeneration
    • DOI 10.1038/ng2131, PII NG2131
    • Maller JB, Fagerness JA, Reynolds RC, Neale BM, Daly MJ, et al. (2007) Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet 39: 1200-1201. (Pubitemid 47482689)
    • (2007) Nature Genetics , vol.39 , Issue.10 , pp. 1200-1201
    • Maller, J.B.1    Fagerness, J.A.2    Reynolds, R.C.3    Neale, B.M.4    Daly, M.J.5    Seddon, J.M.6
  • 27
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454: 428-435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 29
    • 79956028114 scopus 로고    scopus 로고
    • Early focal expression of the chemokine Ccl2 by Müller cells during exposure to damage-inducing bright continuous light
    • Rutar M, Natoli R, Valter K, Provis JM (2011) Early focal expression of the chemokine Ccl2 by Müller cells during exposure to damage-inducing bright continuous light. Invest Ophthalmol Vis Sci 52 (5): 2379-2388.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.5 , pp. 2379-2388
    • Rutar, M.1    Natoli, R.2    Valter, K.3    Provis, J.M.4
  • 30
    • 80052920397 scopus 로고    scopus 로고
    • Analysis of complement expression in light-induced retinal degeneration: Synthesis and deposition of C3 by microglia/macrophages is associated with focal photoreceptor degeneration
    • Rutar M, Natoli R, Valter K, Provis JM (2011) Analysis of complement expression in light-induced retinal degeneration: Synthesis and deposition of C3 by microglia/macrophages is associated with focal photoreceptor degeneration. Invest Ophthalmol Vis Sci 52 (8): 5347-5358.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.8 , pp. 5347-5358
    • Rutar, M.1    Natoli, R.2    Valter, K.3    Provis, J.M.4
  • 31
    • 77954390103 scopus 로고    scopus 로고
    • Brief exposure to damaging light causes focal recruitment of macrophages, and long-term destabilization of photoreceptors in the albino rat retina
    • Rutar M, Provis JM, Valter K (2010) Brief exposure to damaging light causes focal recruitment of macrophages, and long-term destabilization of photoreceptors in the albino rat retina. Curr Eye Res 35: 631-643.
    • (2010) Curr Eye Res , vol.35 , pp. 631-643
    • Rutar, M.1    Provis, J.M.2    Valter, K.3
  • 32
    • 84866272970 scopus 로고    scopus 로고
    • Small interfering RNA-mediated suppression of Ccl2 in Muller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration
    • Rutar MV, Natoli RC, Provis JM (2012) Small interfering RNA-mediated suppression of Ccl2 in Muller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration. J Neuroinflammation 9: 221.
    • (2012) J Neuroinflammation , vol.9 , pp. 221
    • Rutar, M.V.1    Natoli, R.C.2    Provis, J.M.3
  • 33
    • 56149112559 scopus 로고    scopus 로고
    • Gene regulation induced in the C57BL/6J mouse retina by hyperoxia: A temporal microarray study
    • Natoli R, Provis J, Valter K, Stone J (2008) Gene regulation induced in the C57BL/6J mouse retina by hyperoxia: a temporal microarray study. Mol Vis 14: 1983-1994.
    • (2008) Mol Vis , vol.14 , pp. 1983-1994
    • Natoli, R.1    Provis, J.2    Valter, K.3    Stone, J.4
  • 35
    • 0025305837 scopus 로고
    • Messenger RNA levels and methation patterns of GAPDH and beta-actin genes in rat liver, spleen and brain in relation to aging
    • DOI 10.1016/0047-6374(90)90042-E
    • Slagboom PE, de Leeuw WJ, Vijg J (1990) Messenger RNA levels and methylation patterns of GAPDH and beta-actin genes in rat liver, spleen and brain in relation to aging. Mech Ageing Dev 53: 243-257. (Pubitemid 20150564)
    • (1990) Mechanisms of Ageing and Development , vol.53 , Issue.3 , pp. 243-257
    • Slagboom, P.E.1    De Leeuw, W.J.F.2    Vijg, J.3
  • 36
    • 32544457871 scopus 로고    scopus 로고
    • Gradients of cone differentiation and FGF expression during development of the foveal depression in macaque retina
    • DOI 10.1017/S0952523805224069, PII S0952523805224069
    • Cornish EE, Madigan MC, Natoli R, Hales A, Hendrickson AE, et al. (2005) Gradients of cone differentiation and FGF expression during development of the foveal depression in macaque retina. Vis Neurosci 22: 447-459. (Pubitemid 43237769)
    • (2005) Visual Neuroscience , vol.22 , Issue.4 , pp. 447-459
    • Cornish, E.E.1    Madigan, M.C.2    Natoli, R.3    Hales, A.4    Hendrickson, A.E.5    Provis, J.M.6
  • 37
    • 84879881897 scopus 로고    scopus 로고
    • Gene expression changes in aging retinal microglia: Relationship to microglial support functions and regulation of activation
    • Ma W, Cojocaru R, Gotoh N, Gieser L, Villasmil R, et al. (2013) Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation. Neurobiol Aging 34: 2310-2321.
    • (2013) Neurobiol Aging , vol.34 , pp. 2310-2321
    • Ma, W.1    Cojocaru, R.2    Gotoh, N.3    Gieser, L.4    Villasmil, R.5
  • 38
    • 0003113359 scopus 로고
    • Morphological and biochemical comparisons between retinal regions having differing susceptibility to photoreceptor degeneration
    • LaVail MM, Hollyfield JG, Anderson RE, editors. Liss Alan R Inc.
    • Rapp L, Naash M, Wiegand R, et al. (1985) Morphological and biochemical comparisons between retinal regions having differing susceptibility to photoreceptor degeneration. In: LaVail MM, Hollyfield JG, Anderson RE, editors. Retinal Degeneration: Experimental and Clinical Studies: Liss Alan R Inc. 421-437.
    • (1985) Retinal Degeneration: Experimental and Clinical Studies , pp. 421-437
    • Rapp, L.1    Naash, M.2    Wiegand, R.3
  • 39
    • 0019379810 scopus 로고
    • Aging and degeneration of the human macula. I. Outer nuclear layer and photoreceptors
    • Gartner S, Henkind P (1981) Aging and degeneration of the human macula. 1. Outer nuclear layer and photoreceptors. Br J Ophthalmol 65: 23-28. (Pubitemid 11168928)
    • (1981) British Journal of Ophthalmology , vol.65 , Issue.1 , pp. 23-28
    • Gartner, S.1    Henkind, P.2
  • 40
    • 0026502611 scopus 로고
    • Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells
    • Gao H, Hollyfield JG (1992) Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 33: 1-17.
    • (1992) Invest Ophthalmol Vis Sci , vol.33 , pp. 1-17
    • Gao, H.1    Hollyfield, J.G.2
  • 41
    • 0041356894 scopus 로고    scopus 로고
    • Differential expression of GFAP in early v late AMD: A quantitative analysis
    • DOI 10.1136/bjo.87.9.1159
    • Wu KHC, Madigan MC, Billson F, Penfold PL (2003) Differential expression of GFAP in early v late AMD: a quantitative analysis. Br J Ophthalmol 87: 1159-1166. (Pubitemid 37064896)
    • (2003) British Journal of Ophthalmology , vol.87 , Issue.9 , pp. 1159-1166
    • Wu, K.H.C.1    Madigan, M.C.2    Billson, F.A.3    Penfold, P.L.4
  • 42
    • 34249679205 scopus 로고    scopus 로고
    • C1q binding and complement activation by prions and amyloids
    • DOI 10.1016/j.imbio.2007.04.001, PII S0171298507000484
    • Sim RB, Kishore U, Villiers CL, Marche PN, Mitchell DA (2007) C1q binding and complement activation by prions and amyloids. Immunobiology 212: 355-362. (Pubitemid 46825245)
    • (2007) Immunobiology , vol.212 , Issue.4-5 , pp. 355-362
    • Sim, R.B.1    Kishore, U.2    Villiers, C.L.3    Marche, P.N.4    Mitchell, D.A.5
  • 43
    • 5144222255 scopus 로고    scopus 로고
    • Complement: A unique innate immune sensor for danger signals
    • Gasque P (2004) Complement: a unique innate immune sensor for danger signals. Mol Immunol 41: 1089-1098.
    • (2004) Mol Immunol , vol.41 , pp. 1089-1098
    • Gasque, P.1
  • 44
    • 0033921540 scopus 로고    scopus 로고
    • Complement components of the innate immune system in health and disease in the CNS
    • PII S0162310900002186
    • Gasque P, Dean YD, McGreal EP, VanBeek J, Morgan BP (2000) Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology 49: 171-186. (Pubitemid 30445228)
    • (2000) Immunopharmacology , vol.49 , Issue.1-2 , pp. 171-186
    • Gasque, P.1    Dean, Y.D.2    McGreal, E.P.3    Vanbeek, J.4    Morgan, B.P.5
  • 46
    • 0032462810 scopus 로고    scopus 로고
    • C1q knock-out mice for the study of complement deficiency in autoimmune disease
    • Botto M (1998) C1q knock-out mice for the study of complement deficiency in autoimmune disease. Exp Clin Immunogenet 15: 231-234.
    • (1998) Exp Clin Immunogenet , vol.15 , pp. 231-234
    • Botto, M.1
  • 47
    • 0033054390 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and complement deficiency: Clues to a novel role for the classical complement pathway in the maintenance of immune tolerance
    • DOI 10.1016/S0162-3109(99)00018-1, PII S0162310999000181
    • Navratil JS, Korb LC, Ahearn JM (1999) Systemic lupus erythematosus and complement deficiency: clues to a novel role for the classical complement pathway in the maintenance of immune tolerance. Immunopharmacology 42: 47-52. (Pubitemid 29322287)
    • (1999) Immunopharmacology , vol.42 , Issue.1-3 , pp. 47-52
    • Navratil, J.S.1    Korb, L.C.2    Ahearn, J.M.3
  • 48
    • 0031569975 scopus 로고    scopus 로고
    • C1q Binds Directly and Specifically to Surface Blebs of Apoptotic Human Keratinocytes: Complement Deficiency and Systemic Lupus Erythematosus Revisited
    • Korb LC, Ahearn JM (1997) C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited. J Immunol 158: 4525-4528. (Pubitemid 127483768)
    • (1997) Journal of Immunology , vol.158 , Issue.10 , pp. 4525-4528
    • Korb, L.C.1    Ahearn, J.M.2
  • 50
    • 37349079469 scopus 로고    scopus 로고
    • Role of complement and complement regulators in the removal of apoptotic cells
    • DOI 10.1016/j.molimm.2007.09.008, PII S0161589007007390
    • Trouw LA, Blom AM, Gasque P (2008) Role of complement and complement regulators in the removal of apoptotic cells. Mol Immunol 45: 1199-1207. (Pubitemid 350299480)
    • (2008) Molecular Immunology , vol.45 , Issue.5 , pp. 1199-1207
    • Trouw, L.A.1    Blom, A.M.2    Gasque, P.3
  • 51
    • 64649093433 scopus 로고    scopus 로고
    • Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells
    • Gullstrand B, Martensson U, Sturfelt G, Bengtsson AA, Truedsson L (2009) Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells. Clin Exp Immunol 156: 303-311.
    • (2009) Clin Exp Immunol , vol.156 , pp. 303-311
    • Gullstrand, B.1    Martensson, U.2    Sturfelt, G.3    Bengtsson, A.A.4    Truedsson, L.5
  • 52
    • 84875968524 scopus 로고    scopus 로고
    • Complement in immune and inflammatory disorders: Pathophysiological mechanisms
    • Ricklin D, Lambris JD (2013) Complement in immune and inflammatory disorders: pathophysiological mechanisms. J Immunol 190: 3831-3838.
    • (2013) J Immunol , vol.190 , pp. 3831-3838
    • Ricklin, D.1    Lambris, J.D.2
  • 54
    • 80051563642 scopus 로고    scopus 로고
    • Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina
    • Cashman SM, Desai A, Ramo K, Kumar-Singh R (2011) Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina. Invest Ophthalmol Vis Sci 52: 3436-3445.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 3436-3445
    • Cashman, S.M.1    Desai, A.2    Ramo, K.3    Kumar-Singh, R.4
  • 56
    • 67049114123 scopus 로고    scopus 로고
    • Cooperative phagocytes: Resident microglia and bone marrow immigrants remove dead photoreceptors in retinal lesions
    • Joly S, Francke M, Ulbricht E, Beck S, Seeliger M, et al. (2009) Cooperative phagocytes: resident microglia and bone marrow immigrants remove dead photoreceptors in retinal lesions. Am J Pathol 174: 2310-2323.
    • (2009) Am J Pathol , vol.174 , pp. 2310-2323
    • Joly, S.1    Francke, M.2    Ulbricht, E.3    Beck, S.4    Seeliger, M.5
  • 59
    • 77949890579 scopus 로고    scopus 로고
    • Age-related macular degeneration: The molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: The Proctor lecture
    • Hollyfield JG (2010) Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture. Invest Ophthalmol Vis Sci 51: 1275-1281.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1275-1281
    • Hollyfield, J.G.1
  • 61
    • 33947160639 scopus 로고    scopus 로고
    • Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments
    • DOI 10.1016/j.exer.2006.11.015, PII S001448350600457X
    • Chen M, Forrester JV, Xu H (2007) Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments. Exp Eye Res 84: 635-645. (Pubitemid 46400631)
    • (2007) Experimental Eye Research , vol.84 , Issue.4 , pp. 635-645
    • Chen, M.1    Forrester, J.V.2    Xu, H.3
  • 62
    • 80055078031 scopus 로고    scopus 로고
    • The effect of photo-oxidative stress and inflammatory cytokine on complement factor H expression in retinal pigment epithelial cells
    • Lau LI, Chiou SH, Liu CJ, Yen MY, Wei YH (2011) The effect of photo-oxidative stress and inflammatory cytokine on complement factor H expression in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 52: 6832-6841.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 6832-6841
    • Lau, L.I.1    Chiou, S.H.2    Liu, C.J.3    Yen, M.Y.4    Wei, Y.H.5
  • 63
    • 0029562829 scopus 로고
    • Lipofuscin of the retinal pigment epithelium: A review
    • Kennedy CJ, Rakoczy PE, Constable IJ (1995) Lipofuscin of the retinal pigment epithelium: a review. Eye (Lond) 9 (Pt 6): 763-771. (Pubitemid 26018204)
    • (1995) Eye , vol.9 , Issue.6 , pp. 763-771
    • Kennedy, C.J.1    Rakoczy, P.E.2    Constable, I.J.3
  • 64
    • 84899412796 scopus 로고    scopus 로고
    • A2E accumulation influences retinal microglial activation and complement regulation
    • Ma W, Coon S, Zhao L, Fariss RN, Wong WT (2012) A2E accumulation influences retinal microglial activation and complement regulation. Neurobiol Aging.
    • (2012) Neurobiol Aging
    • Ma, W.1    Coon, S.2    Zhao, L.3    Fariss, R.N.4    Wong, W.T.5
  • 65
    • 84862815733 scopus 로고    scopus 로고
    • Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent
    • Chen M, Zhao J, Luo C, Pandi SP, Penalva RG, et al. (2012) Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent. Glia 60: 833-842.
    • (2012) Glia , vol.60 , pp. 833-842
    • Chen, M.1    Zhao, J.2    Luo, C.3    Pandi, S.P.4    Penalva, R.G.5
  • 66
    • 34247121167 scopus 로고    scopus 로고
    • Epidemiology of Age-related macular degeneration
    • Penfold P, Provis J, editors. Berlin: Springer-Verlag
    • Klein R (2005) Epidemiology of Age-related macular degeneration. In: Penfold P, Provis J, editors. Macular Degeneration. Berlin: Springer-Verlag.
    • (2005) Macular Degeneration
    • Klein, R.1
  • 67
    • 79952115892 scopus 로고    scopus 로고
    • The case for complement and inflammation in AMD: Open questions
    • Karagianni N, Adamis AP The case for complement and inflammation in AMD: open questions. Adv Exp Med Biol 703: 1-7.
    • Adv Exp Med Biol , vol.703 , pp. 1-7
    • Karagianni, N.1    Adamis, A.P.2
  • 68
    • 85027939027 scopus 로고    scopus 로고
    • Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks
    • Newman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, et al. (2012) Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. Genome Med 4: 16.
    • (2012) Genome Med , vol.4 , pp. 16
    • Newman, A.M.1    Gallo, N.B.2    Hancox, L.S.3    Miller, N.J.4    Radeke, C.M.5
  • 69
    • 42449105692 scopus 로고    scopus 로고
    • Immunopathological aspects of age-related macular degeneration
    • Patel M, Chan CC (2008) Immunopathological aspects of age-related macular degeneration. Semin Immunopathol 30: 97-110.
    • (2008) Semin Immunopathol , vol.30 , pp. 97-110
    • Patel, M.1    Chan, C.C.2
  • 71
    • 0022590076 scopus 로고
    • Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium
    • Penfold PL, Killingsworth MC, Sarks SH (1986) Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium. Invest Ophthalmol Vis Sci 27: 364-271.
    • (1986) Invest Ophthalmol Vis Sci , vol.27 , pp. 364-1271
    • Penfold, P.L.1    Killingsworth, M.C.2    Sarks, S.H.3
  • 72
    • 77954397594 scopus 로고    scopus 로고
    • Quantification of leukocyte common antigen (CD45) expression in macular degeneration
    • Wong J, Madigan M, Billson F, Penfold P (2001) Quantification of leukocyte common antigen (CD45) expression in macular degeneration. Invest Ophthalmol Vis Sci 42: S227.
    • (2001) Invest Ophthalmol Vis Sci , vol.42
    • Wong, J.1    Madigan, M.2    Billson, F.3    Penfold, P.4
  • 75
    • 84887096324 scopus 로고    scopus 로고
    • CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice
    • Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, et al. (2013) CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. EMBO Mol Med 5: 1775-1793.
    • (2013) EMBO Mol Med , vol.5 , pp. 1775-1793
    • Sennlaub, F.1    Auvynet, C.2    Calippe, B.3    Lavalette, S.4    Poupel, L.5
  • 76
    • 73349097249 scopus 로고    scopus 로고
    • The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages
    • Luhmann UF, Robbie S, Munro PM, Barker SE, Duran Y, et al. (2009) The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages. Invest Ophthalmol Vis Sci 50: 5934-5943.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 5934-5943
    • Luhmann, U.F.1    Robbie, S.2    Munro, P.M.3    Barker, S.E.4    Duran, Y.5


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