Analysis of complement expression in light-induced retinal degeneration: Synthesis and deposition of C3 by microglia/macrophages is associated with focal photoreceptor degeneration

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 8, 2011, Pages 5347-5358

  Rutar, Matt ^a   Natoli, Riccardo ^a,b   Kozulin, Peter ^a   Valter, Krisztina ^a   Gatenby, Paul ^b   Provis, Jan M ^a,b  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b Canberra Hospital   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C1R; COMPLEMENT COMPONENT C1S; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3 RECEPTOR; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C4A; COMPLEMENT COMPONENT C4B; DECAY ACCELERATING FACTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MEMBRANE COFACTOR PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; COMPLEMENT SYSTEM; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIGHT EXPOSURE; MACROPHAGE; MICROARRAY ANALYSIS; MICROGLIA; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C JUN; PHOTORECEPTOR; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA DEGENERATION; ANIMAL; APOPTOSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LIGHT; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RADIATION EXPOSURE; RADIATION INJURY; RETINA; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; COMPLEMENT C3; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; IN SITU NICK-END LABELING; LIGHT; MACROPHAGES; MICROGLIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; RADIATION INJURIES, EXPERIMENTAL; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL DEGENERATION; RNA, MESSENGER;

EID: 80052920397     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-7119     Document Type: Article

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